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  • Ralph L Sacco
2020

Antithrombotic Treatment of Embolic Stroke of Undetermined Source: RE-SPECT ESUS Elderly and Renally Impaired Subgroups

Diener, H. C., Sacco, R. L., Easton, J. D., Granger, C. B., Bar, M., Bernstein, R. A., Brainin, M., Brueckmann, M., Cronin, L., Donnan, G., Gdovinová, Z., Grauer, C., Kleine, E., Kleinig, T. J., Lyrer, P., Martins, S., Meyerhoff, J., Milling, T., Pfeilschifter, W., Poli, S. & 4 others, Reif, M., Rose, D. Z., Šaňák, D. & Schäbitz, W. R., 2020, (Accepted/In press) In : Stroke. p. 1758-1765 8 p.

Research output: Contribution to journalArticle

Open Access

Association between Blood Pressure and Later-Life Cognition among Black and White Individuals

Levine, D. A., Gross, A. L., Briceño, E. M., Tilton, N., Kabeto, M. U., Hingtgen, S. M., Giordani, B. J., Sussman, J. B., Hayward, R. A., Burke, J. F., Elkind, M. S. V., Manly, J. J., Moran, A. E., Kulick, E. R., Gottesman, R. F., Walker, K. A., Yano, Y., Gaskin, D. J., Sidney, S., Yaffe, K. & 5 others, Sacco, R. L., Wright, C. B., Roger, V. L., Allen, N. B. & Galecki, A. T., Jan 1 2020, (Accepted/In press) In : JAMA Neurology.

Research output: Contribution to journalArticle

2 Scopus citations

Association between Central Blood Pressure and Subclinical Cerebrovascular Disease in Older Adults

Matsumoto, K., Jin, Z., Homma, S., Elkind, M. S. V., Rundek, T., Mannina, C., Lee, T. C., Yoshita, M., Decarli, C., Wright, C. B., Sacco, R. L. & Di Tullio, M. R., Feb 1 2020, In : Hypertension. p. 580-587 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Association between PNPLA3 rs738409 G variant and MRI cerebrovascular disease biomarkers

Parikh, N. S., Dueker, N., Varela, D., Del Brutto, V. J., Rundek, T., Wright, C. B., Sacco, R. L., Elkind, M. S. V. & Gutierrez, J., Sep 15 2020, In : Journal of the Neurological Sciences. 416, 116981.

Research output: Contribution to journalArticle

Brain Volume: An Important Determinant of Functional Outcome After Acute Ischemic Stroke

MRI-GENIE and GISCOME Investigators and the International Stroke Genetics Consortium, May 2020, In : Mayo Clinic Proceedings. 95, 5, p. 955-965 11 p.

Research output: Contribution to journalArticle

Cholinergic White Matter Lesions, AD-Signature Cortical Thickness, and Change in Cognition: The Northern Manhattan Study

Caunca, M. R., Siedlecki, K., Cheung, Y. K., Alperin, N., Lee, S. H., Elkind, M. S. V., Sacco, R. L., Wright, C. B. & Rundek, T., Jul 13 2020, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 75, 8, p. 1508-1515 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Classification of Covert Brain Infarct Subtype and Risk of Death and Vascular Events

Gutierrez, J., Gil-Guevara, A., Ramaswamy, S., DeRosa, J., Di Tullio, M. R., Cheung, K., Rundek, T., Sacco, R. L., Wright, C. B. & Elkind, M. S. V., Jan 1 2020, In : Stroke. 51, 1, p. 90-98 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Creatinine versus cystatin C for renal function-based mortality prediction in an elderly cohort: The Northern Manhattan study

Willey, J. Z., Moon, Y. P., Ali Husain, S., Elkind, M. S. V., Sacco, R. L., Wolf, M., Cheung, K., Wright, C. B. & Mohan, S., Jan 1 2020, In : PloS one. 15, 1, e0226509.

Research output: Contribution to journalArticle

Open Access

De novo EIF2AK1 and EIF2AK2 Variants Are Associated with Developmental Delay, Leukoencephalopathy, and Neurologic Decompensation

Undiagnosed Diseases Network, Apr 2 2020, In : American journal of human genetics. 106, 4, p. 570-583 14 p.

Research output: Contribution to journalArticle

Detailed phenotyping of posterior vs. anterior circulation ischemic stroke: a multi-center MRI study

the Stroke Genetics Network (SiGN), the International Stroke Genetics Consortium (ISGC), and the MRI-Genetics Interface Exploration (MRI-GENIE) Study, Mar 1 2020, In : Journal of Neurology. 267, 3, p. 649-658 10 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Diastolic Blood Pressure Is Associated with Regional White Matter Lesion Load: The Northern Manhattan Study

Caunca, M. R., Simonetto, M., Cheung, Y. K., Alperin, N., Lee, S. H., Elkind, M. S. V., Sacco, R. L., Rundek, T. & Wright, C. B., Feb 1 2020, In : Stroke. p. 372-378 7 p.

Research output: Contribution to journalArticle

Global Vascular Risk Score and CAIDE Dementia Risk Score Predict Cognitive Function in the Northern Manhattan Study

Rundek, T., Gardener, H., Dias Saporta, A. S., Loewenstein, D. A., Duara, R., Wright, C. B., Dong, C., Levin, B., Elkind, M. S. V. & Sacco, R. L., Jan 1 2020, In : Journal of Alzheimer's disease : JAD. 73, 3, p. 1221-1231 11 p.

Research output: Contribution to journalArticle

Long-term exposure to air pollution and trajectories of cognitive decline among older adults

Kulick, E. R., Wellenius, G. A., Boehme, A. K., Joyce, N. R., Schupf, N., Kaufman, J. D., Mayeux, R., Sacco, R. L., Manly, J. J. & Elkind, M. S. V., Apr 28 2020, In : Neurology. 94, 17, p. E1782-E1792

Research output: Contribution to journalArticle

5 Scopus citations

Machine learning-based estimation of cognitive performance using regional brain MRI markers: the Northern Manhattan Study

Caunca, M. R., Wang, L., Cheung, Y. K., Alperin, N., Lee, S. H., Elkind, M. S. V., Sacco, R. L., Wright, C. B. & Rundek, T., 2020, (Accepted/In press) In : Brain Imaging and Behavior.

Research output: Contribution to journalArticle

Multiple Faces of Cerebral Small Vessel Diseases

Gurol, M. E., Sacco, R. L. & McCullough, L. D., Jan 1 2020, In : Stroke. 51, 1, p. 9-11 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Progression of conventional cardiovascular risk factors and vascular disease risk in individuals: insights from the PROG-IMT consortium

on behalf of the PROG-IMT study group, Feb 1 2020, In : European Journal of Preventive Cardiology. 27, 3, p. 234-243 10 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Race and Ethnic Disparities in Stroke Incidence in the Northern Manhattan Study

Gardener, H., Sacco, R. L., Rundek, T., Battistella, V., Cheung, Y. K. & Elkind, M. S. V., Apr 1 2020, In : Stroke. p. 1064-1069 6 p.

Research output: Contribution to journalArticle

Open Access

Randomized Trial of Combined Aerobic, Resistance, and Cognitive Training to Improve Recovery From Stroke: Feasibility and Safety

Koch, S., Tiozzo, E., Simonetto, M., Loewenstein, D., Wright, C. B., Dong, C., Bustillo, A., Perez-Pinzon, M., Dave, K. R., Gutierrez, C. M., Lewis, J. E., Flothmann, M., Mendoza-Puccini, M. C., Junco, B., Rodriguez, Z., Gomes-Osman, J., Rundek, T. & Sacco, R. L., May 18 2020, In : Journal of the American Heart Association. 9, 10, p. e015377

Research output: Contribution to journalArticle

Open Access

Response by Gutierrez et al to Letter Regarding Article, "classification of Covert Brain Infarct Subtype and Risk of Death and Vascular Events"

Gutierrez, J., Di Tullio, M. R., Rundek, T., Sacco, R. L., Wright, C. B. & Elkind, M. S. V., 2020, (Accepted/In press) In : Stroke. p. E82

Research output: Contribution to journalLetter

Rising Incidence of Stroke in Pregnancy: A Call for Enhanced Screening and Prevention

Sacco, R. L. & Sur, N. B., Jan 21 2020, In : Journal of the American College of Cardiology. 75, 2, p. 191-193 3 p.

Research output: Contribution to journalEditorial

Sleep quality mediates the relationship between frailty and cognitive dysfunction in non-demented middle aged to older adults

Kaur, S., Banerjee, N., Miranda, M., Slugh, M., Suslow, N. S., McInerney, K. F., Sun, X., Ramos, A., Rundek, T., Sacco, R. L. & Levin, B. E., Jan 1 2020, (Accepted/In press) In : International Psychogeriatrics.

Research output: Contribution to journalLetter

Open Access

Stroke Vision 2020: Creating a roadmap for the next decade

Sacco, R. L., Mar 1 2020, In : Stroke. p. 1040-1046 7 p.

Research output: Contribution to journalReview article

Open Access

The american heart association 2030 impact goal: A presidential advisory from the american heart association

Angell, S. Y., Mcconnell, M. V., Anderson, C. A. M., Bibbins-Domingo, K., Boyle, D. S., Capewell, S., Ezzati, M., De Ferranti, S., Gaskin, D. J., Goetzel, R. Z., Huffman, M. D., Jones, M., Khan, Y. M., Kim, S., Kumanyika, S. K., Mccray, A. T., Merritt, R. K., Milstein, B., Mozaffarian, D., Norris, T. & 7 others, Roth, G. A., Sacco, R. L., Saucedo, J. F., Shay, C. M., Siedzik, D., Saha, S. & Warner, J. J., Mar 3 2020, In : Circulation. p. E120-E138

Research output: Contribution to journalReview article

6 Scopus citations
2018

Adjudication of Transient Ischemic Attack and Stroke in the Multi-Ethnic Study of Atherosclerosis

Longstreth, W. T., Gasca, N. C., Gottesman, R. F., Pearce, J. B. & Sacco, R. L., Mar 1 2018, In : Neuroepidemiology. 50, 1-2, p. 23-28 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Apolipoprotein E Gene Polymorphism and Subclinical Carotid Atherosclerosis: The Northern Manhattan Study

Doliner, B., Dong, C., Blanton, S. H., Gardener, H., Elkind, M. S. V., Sacco, R. L., Demmer, R. T., Desvarieux, M. & Rundek, T., Mar 2018, In : Journal of Stroke and Cerebrovascular Diseases. 27, 3, p. 645-652 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Association between carotid artery function and structure in the Northern Manhattan Study

Della-Morte, D., Gardener, H., Dong, C., Markert, M., Cabral, D., Elkind, M. S. V., Sacco, R. L. & Rundek, T., Apr 16 2018, In : Frontiers in Neurology. 9, APR, 246.

Research output: Contribution to journalArticle

3 Scopus citations

Association between heart rate and subclinical cerebrovascular disease in the elderly

Nakanishi, K., Jin, Z., Homma, S., Elkind, M. S. V., Rundek, T., Lee, S. C., Tugcu, A., Yoshita, M., DeCarli, C., Wright, C. B., Sacco, R. L. & Di Tullio, M. R., 2018, In : Stroke. 49, 2, p. 319-324 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Association Between Subclinical Brain Infarcts and Functional Decline Trajectories

Dhamoon, M. S., Cheung, Y. K., DeRosa, J. T., Gutierrez, J., Moon, Y. P., Sacco, R. L., Elkind, M. S. V. & Wright, C. B., Nov 2018, In : Journal of the American Geriatrics Society. 66, 11, p. 2144-2150 7 p.

Research output: Contribution to journalArticle

Association of body size metrics with left atrial phasic volumes and reservoir function in the elderly

Tugcu, A., Russo, C., Jin, Z., Homma, S., Nakanishi, K., Elkind, M. S. V., Rundek, T., Sacco, R. L. & Di Tullio, M. R., Oct 1 2018, In : European Heart Journal Cardiovascular Imaging. 19, 10, p. 1157-1164 8 p.

Research output: Contribution to journalArticle

Brain arterial diameters and cognitive performance: The Northern Manhattan study

Gutierrez, J., Kulick, E., Park Moon, Y., Dong, C., Cheung, K., Ahmet, B., Stern, Y., Alperin, N., Rundek, T., Sacco, R. L., Wright, C. B. & Elkind, M. S. V., Apr 1 2018, In : Journal of the International Neuropsychological Society. 24, 4, p. 335-346 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Carotid intima-media thickness is associated with white matter hyperintensities the Northern Manhattan Study

Della-Morte, D., Dong, C., Markert, M. S., Elkind, M. S. V., Sacco, R. L., Wright, C. B. & Rundek, T., 2018, In : Stroke. 49, 2, p. 304-311 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Cerebral white matter disease and functional decline in older adults from the Northern Manhattan Study: A longitudinal cohort study

Dhamoon, M. S., Cheung, Y. K., Moon, Y., DeRosa, J., Sacco, R., Elkind, M. S. V. & Wright, C. B., Mar 2018, In : PLoS Medicine. 15, 3, e1002529.

Research output: Contribution to journalArticle

4 Scopus citations

Coronary artery calcium and carotid artery intima-media thickness for the prediction of stroke and benefit from statins

Osawa, K., Trejo, M. E. P., Nakanishi, R., McClelland, R. L., Blaha, M. J., Blankstein, R., McEvoy, J. W., Ceponiene, I., Stein, J. H., Sacco, R. L., Polak, J. F. & Budoff, M. J., Dec 1 2018, In : European Journal of Preventive Cardiology. 25, 18, p. 1980-1987 8 p.

Research output: Contribution to journalArticle

12 Scopus citations
1 Scopus citations

Cox model with interval-censored covariate in cohort studies

Ahn, S., Lim, J., Paik, M. C., Sacco, R. L. & Elkind, M. S., Jul 2018, In : Biometrical Journal. 60, 4, p. 797-814 18 p.

Research output: Contribution to journalArticle

1 Scopus citations

Creatinine-versus cystatin C-based renal function assessment in the Northern Manhattan Study

Husain, S. A., Willey, J. Z., Moon, Y. P., Elkind, M. S. V., Sacco, R. L., Wolf, M., Cheung, K., Wright, C. B. & Mohan, S., Nov 2018, In : PloS one. 13, 11, e0206839.

Research output: Contribution to journalArticle

3 Scopus citations

Diet soda and sugar-sweetened soda consumption in relation to incident diabetes in the Northern Manhattan Study

Gardener, H., Moon, Y. P., Rundek, T., Elkind, M. S. V. & Sacco, R. L., May 1 2018, In : Current Developments in Nutrition. 2, 5, nzy008.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Electrocardiographic left atrial abnormality and silent vascular brain injury: The Northern Manhattan Study

Hunter, M. D., Moon, Y. P., DeCarli, C., Gutierrez, J., Wright, C. B., Tullio, M. R. D., Sacco, R. L., Kamel, H. & Elkind, M. S. V., Oct 2018, In : PloS one. 13, 10, e0203774.

Research output: Contribution to journalArticle

1 Scopus citations

Functional trajectories, cognition, and subclinical cerebrovascular disease

Dhamoon, M. S., Cheung, Y. K., Gutierrez, J., Moon, Y. P., Sacco, R. L., Elkind, M. S. V. & Wright, C. B., 2018, In : Stroke. 49, 3, p. 549-555 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Greater depressive symptoms, cognition, and markers of brain aging: Northern Manhattan Study

Zeki Al Hazzouri, A., Caunca, M. R., Nobrega, J. C., Elfassy, T., Cheung, Y. K., Alperin, N., Dong, C., Elkind, M. S. V., Sacco, R. L., DeCarli, C. & Wright, C. B., Jun 5 2018, In : Neurology. 90, 23, p. e2077-e2085

Research output: Contribution to journalArticle

2 Scopus citations

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

MEGASTROKE Consortium, Dec 1 2018, In : Nature communications. 9, 1, 5141.

Research output: Contribution to journalArticle

21 Scopus citations

Heart Failure Severity and Quality of Warfarin Anticoagulation Control (From the WARCEF Trial)

The WARCEF Investigators, Sep 1 2018, In : American Journal of Cardiology. 122, 5, p. 821-827 7 p.

Research output: Contribution to journalArticle

Hypertension in Florida: Data from the one Florida clinical data research network

Smith, S. M., McAuliffe, K., Hall, J. M., McDonough, C. W., Gurka, M. J., Robinson, T. O., Sacco, R. L., Pepine, C., Shenkman, E. & Cooper-DeHoff, R. M., Mar 1 2018, In : Preventing Chronic Disease. 15, 3, 170332.

Research output: Contribution to journalArticle

4 Scopus citations

Ideal cardiovascular health and biomarkers of subclinical brain aging: The northern Manhattan study

Gardener, H., Caunca, M., Dong, C., Cheung, Y. K., Alperin, N., Rundek, T., Elkind, M. S. V., Wright, C. B. & Sacco, R. L., Aug 1 2018, In : Journal of the American Heart Association. 7, 16, e009544.

Research output: Contribution to journalArticle

2 Scopus citations

Ischemic stroke/transient ischemic attack events and carotid artery disease in the absence of or with minimal coronary artery calcification: Results from the Multi-Ethnic Study of Atherosclerosis

Osawa, K., Nakanishi, R., McClelland, R. L., Polak, J. F., Bishop, W., Sacco, R. L., Ceponiene, I., Nezarat, N., Rahmani, S., Qi, H., Kanisawa, M. & Budoff, M. J., Aug 2018, In : Atherosclerosis. 275, p. 22-27 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Left atrial volume and cardiovascular outcomes in systolic heart failure: effect of antithrombotic treatment

for the WARCEF Investigators, Oct 2018, In : ESC Heart Failure. 5, 5, p. 800-808 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Neurology Working Group of the CHARGE Consortium, NINDS Stroke Genetics Network (SiGN), UK Young Lacunar DNA Study, MEGAST ROKE Consortium, AFGen Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, International Genomics of Blood Pressure (iGEN-BP) Consortium, INVENT Consortium, STA RNET BioBank Japan Cooperative Hospital Group, COMPASS Consortium, EPIC-CVD Consortium, EPIC-InterAct Consortium, International Stroke Genetics Consortium (ISGC) & METAST ROKE Consortium, Apr 1 2018, In : Nature genetics. 50, 4, p. 524-537 14 p.

Research output: Contribution to journalArticle

175 Scopus citations

Neurological Complications Following Aortic Valve Replacement: TAVR Better Than SAVR, But Room for Improvement

Rodés-Cabau, J. & Sacco, R. L., Oct 30 2018, In : Journal of the American College of Cardiology. 72, 18, p. 2120-2122 3 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Periventricular White Matter Hyperintensities and Functional Decline

Dhamoon, M. S., Cheung, Y. K., Bagci, A., Alperin, N., Sacco, R. L., Elkind, M. S. V. & Wright, C. B., Jan 2018, In : Journal of the American Geriatrics Society. 66, 1, p. 113-119 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
18 Scopus citations