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  • William K Scott
2020

A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration

International AMD Genomics Consortium (IAMDGC), Dec 1 2020, In : Scientific reports. 10, 1, 1584.

Research output: Contribution to journalArticle

Open Access

Spectrum of genetic variants associated with anterior segment dysgenesis in South Florida

Thanikachalam, S., Hodapp, E. A., Chang, T. C., Swols, D. M., Cengiz, F. B., Guo, S., Zafeer, M. F., Seyhan, S., Bademci, G., Scott, W. K., Grajewski, A. & Tekin, M., Apr 2020, In : Genes. 11, 4, 350.

Research output: Contribution to journalArticle

Open Access
2017

A chromosome 5q31.1 locus associates with tuberculin skin test reactivity in HIV-positive individuals from tuberculosis hyper-endemic regions in east Africa

Sobota, R. S., Stein, C. M., Kodaman, N., Maro, I., Wieland-Alter, W., Igo, R. P., Magohe, A., Malone, L. S. L., Chervenak, K., Hall, N. B., Matee, M., Mayanja-Kizza, H., Joloba, M., Moore, J. H., Scott, W. K., Lahey, T., Boom, W. H., von Reyn, C. F., Williams, S. M. & Sirugo, G., 2017, In : PLoS genetics. 13, 6, e1006710.

Research output: Contribution to journalArticle

6 Scopus citations

Age at natural menopause genetic risk score in relation to age at natural menopause and primary open-angle glaucoma in a US-based sample

Pasquale, L. R., Aschard, H., Kang, J. H., Bailey, J. N. C., Lindström, S., Chasman, D. I., Christen, W. G., Allingham, R. R., Ashley-Koch, A., Lee, R. K., Moroi, S. E., Brilliant, M. H., Wollstein, G., Schuman, J. S., Fingert, J., Budenz, D. L., Realini, T., Gaasterland, T., Gaasterland, D., Scott, W. K. & 21 others, Singh, K., Sit, A. J., Igo, R. P., Song, Y. E., Hark, L., Ritch, R., Rhee, D. J., Gulati, V., Havens, S., Vollrath, D., Zack, D. J., Medeiros, F., Weinreb, R. N., Pericak-Vance, M. A., Liu, Y., Kraft, P., Richards, J. E., Rosner, B. A., Hauser, M. A., Haines, J. L. & Wiggs, J. L., Jan 1 2017, In : Menopause. 24, 2, p. 150-156 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

A population-specific reference panel empowers genetic studies of Anabaptist populations

Hou, L., Kember, R. L., Roach, J. C., O'Connell, J. R., Craig, D. W., Bucan, M., Scott, W. K., Pericak-Vance, M. A., Haines, J. L., Crawford, M. H., Shuldiner, A. R. & McMahon, F. J., Dec 1 2017, In : Scientific Reports. 7, 1, 6079.

Research output: Contribution to journalArticle

5 Scopus citations

Candidate genes on murine chromosome 8 are associated with susceptibility to Staphylococcus aureus infection in mice and are involved with Staphylococcus aureus septicemia in humans

Yan, Q., Ahn, S. H., Medie, F. M., Sharma-Kuinkel, B. K., Park, L. P., Scott, W. K., Deshmukh, H., Tsalik, E. L., Cyr, D. D., Woods, C. W., Yu, C. H. A., Adams, C., Qi, R., Hansen, B. & Fowler, V. G., Jun 2017, In : PloS one. 12, 6, e0179033.

Research output: Contribution to journalArticle

2 Scopus citations

Evaluating genetic susceptibility to Staphylococcus aureus bacteremia in African Americans using admixture mapping

Cyr, D. D., Allen, A. S., Du, G. J., Ruffin, F., Adams, C., Thaden, J. T., Maskarinec, S. A., Souli, M., Guo, S., Dykxhoorn, D. M., Scott, W. K. & Fowler, V. G., Mar 23 2017, (Accepted/In press) In : Genes and Immunity.

Research output: Contribution to journalArticle

11 Scopus citations

Generation of disease-specific autopsy-confirmed iPSCs lines from postmortem isolated Peripheral Blood Mononuclear Cells

Belle, K., Shabazz, F. S., Nuytemans, K., Davis, D. A., Ali, A., Young, J., Scott, W. K., Mash, D. C., Vance, J. M. & Dykxhoorn, D. M., Jan 10 2017, In : Neuroscience Letters. 637, p. 201-206 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Genetic correlations between intraocular pressure, blood pressure and primary open-angle glaucoma: A multi-cohort analysis

Aschard, H., Kang, J. H., Iglesias, A. I., Hysi, P., Cooke Bailey, J. N., Khawaja, A. P., Allingham, R. R., Ashley-Koch, A., Lee, R. K., Moroi, S. E., Brilliant, M. H., Wollstein, G., Schuman, J. S., Fingert, J. H., Budenz, D. L., Realini, T., Gaasterland, T., Scott, W. K., Singh, K., Sit, A. J. & 25 others, Igo, R. P., Song, Y. E., Hark, L., Ritch, R., Rhee, D. J., Gulati, V., Haven, S., Vollrath, D., Zack, D. J., Medeiros, F., Weinreb, R. N., Cheng, C. Y., Chasman, D. I., Christen, W. G., Pericak-Vance, M. A., Liu, Y., Kraft, P., Richards, J. E., Rosner, B. A., Hauser, M. A., Klaver, C. C. W., Vanduijn, C. M., Haines, J., Wiggs, J. L. & Pasquale, L. R., Nov 1 2017, In : European Journal of Human Genetics. 25, 11, p. 1261-1267 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits

International AMD Genomics Consortium (IAMDGC), Mar 27 2017, In : Genome Medicine. 9, 1, 29.

Research output: Contribution to journalArticle

27 Scopus citations

Joint Analysis of Nuclear and Mitochondrial Variants in Age-Related Macular Degeneration Identifies Novel Loci TRPM1 and ABHD2/RLBP1

for the International Age-Related Macular Degeneration Genomics Consortium (IAMDGC), Aug 1 2017, In : Investigative ophthalmology & visual science. 58, 10, p. 4027-4038 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Recombinant haplotypes narrow the ARMS2/HTRA1 association signal for age-related macular degeneration

International AMD Genomics Consortium (IAMDGC), Feb 2017, In : Genetics. 205, 2, p. 919-924 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility

Chintalapudi, S. R., Maria, D., Di Wang, X., Bailey, J. N. C., Allingham, R., Brilliant, M., Budenz, D., Fingert, J., Gaasterland, D., Gaasterland, T., Haines, J. L., Hark, L., Hauser, M., Igo, R., Hee Kang, J., Kraft, P., Lee, R., Lichter, P., Liu, Y., Moroi, S. & 43 others, Pasquale, L. R., Pericak-Vance, M., Realini, A., Rhee, D., Richards, J. R., Ritch, R., Schuman, J., Scott, W. K., Singh, K., Sit, A., Vollrath, D., Wollstein, G., Zack, D., Aung, T., Bonnemaijer, P., Cheng, C. Y., Craig, J., Van Duijn, C., Gharahkhani, P., Iglesias Gonzalez, A., Hammond, C. J., Hewitt, A., Hoehn, R., Jonansson, F., Khawaja, A., Chuen Khor, C., Klaver, C. C. W., Lotery, A., MacKey, D., MacGregor, S., Pang, C., Pasutto, F., Stefansson, K., Thorleifsson, G., Thorsteinsdottir, U., Vitart, V., Vithana, E., Young, T., Zeller, T., Hysi, P. G., Wiggs, J. L., Williams, R. W. & Jablonski, M. M., Dec 1 2017, In : Nature communications. 8, 1, 1755.

Research output: Contribution to journalArticle

8 Scopus citations
2016

A common variant in MIR182 is associated with primary open-angle glaucoma in the NEIGHBORHOOD consortium

Liu, Y., Bailey, J. C., Helwa, I., Dismuke, W. M., Cai, J., Drewry, M., Brilliant, M. H., Budenz, D. L., Christen, W. G., Chasman, D. I., Fingert, J. H., Gaasterland, D., Gaasterland, T., Gordon, M. O., Igo, R. P., Kang, J. H., Kass, M. A., Kraft, P., Lee, R. K., Lichter, P. & 25 others, Moroi, S. E., Realini, A., Richards, J. E., Ritch, R., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Song, Y. E., Vollrath, D., Weinreb, R., Medeiros, F., Wollstein, G., Zack, D. J., Zhang, K., Pericak-Vance, M. A., Gonzalez, P., Stamer, W. D., Kuchtey, J., Kuchtey, R. W., Allingham, R. R., Hauser, M. A., Pasquale, L. R., Haines, J. L. & Wiggs, J. L., Aug 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 10, p. 4528-4535 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

Fritsche, L. G., Igl, W., Bailey, J. N. C., Grassmann, F., Sengupta, S., Bragg-Gresham, J. L., Burdon, K. P., Hebbring, S. J., Wen, C., Gorski, M., Kim, I. K., Cho, D., Zack, D., Souied, E., Scholl, H. P. N., Bala, E., ELee, K., Hunter, D. J., Sardell, R. J., Mitchell, P. & 142 others, Merriam, J. E., Cipriani, V., Hoffman, J. D., Schick, T., Lechanteur, Y. T. E., Guymer, R. H., Johnson, M. P., Jiang, Y., Stanton, C. M., Buitendijk, G. H. S., Zhan, X., Kwong, A. M., Boleda, A., Brooks, M., Gieser, L., Ratnapriya, R., Branham, K. E., Foerster, J. R., Heckenlively, J. R., Othman, M. I., Vote, B. J., Liang, H. H., Souzeau, E., McAllister, I. L., Isaacs, T., Hall, J., Lake, S., Mackey, D. A., Constable, I. J., Craig, J. E., Kitchner, T. E., Yang, Z., Su, Z., Luo, H., Chen, D., Ouyang, H., Flagg, K., Lin, D., Mao, G., Ferreyra, H., Stark, K., Von Strachwitz, C. N., Wolf, A., Brandl, C., Rudolph, G., Olden, M., Morrison, M. A., Morgan, D. J., Schu, M., Ahn, J., Silvestri, G., Tsironi, E. E., Park, K. H., Farrer, L. A., Orlin, A., Brucker, A., Li, M., Curcio, C. A., Mohand-Sa'd, S., Sahel, J. A., Audo, I., Benchaboune, M., Cree, A. J., Rennie, C. A., Goverdhan, S. V., Grunin, M., Hagbi-Levi, S., Campochiaro, P., Katsanis, N., Holz, F. G., Blond, F., Blanché, H., Deleuze, J. F. O., Igo, R. P., Truitt, B., Peachey, N. S., Meuer, S. M., Myers, C. E., Moore, E. L., Klein, R., Hauser, M. A., Postel, E. A., Courtenay, M. D., Schwartz, S. G., Kovach, J. L., Scott, W. K., Liew, G., Tan, A. G., Gopinath, B., Merriam, J. C., Smith, R. T., Khan, J. C., Shahid, H., Moore, A. T., McGrath, J. A., Laux, R., Brantley, M. A., Agarwal, A., Ersoy, L., Caramoy, A., Langmann, T., Saksens, N. T. M., Jong, E. K., Hoyng, C. B., Cain, M. S., Richardson, A. J., Martin, T. M., Blangero, J., Weeks, D. E., Dhillon, B., Van Duijn, C. M., Doheny, K. F., Romm, J., Klaver, C. C. W., Hayward, C., Gorin, M. B., Klein, M. L., Baird, P. N., Den Hollander, A. I., Fauser, S., WYates, J. R., Allikmets, R., Wang, J. J., Schaumberg, D. A., Klein, B. E. K., Hagstrom, S. A., Chowers, I., Lotery, A. J., Léveillard, T., Zhang, K., Brilliant, M. H., Hewitt, A. W., Swaroop, A., Chew, E. Y., Pericak-Vance, M. A., DeAngelis, M., Stambolian, D., Haines, J. L., Iyengar, S. K., Weber, B. H. F., Abecasis, G. R. & Heid, I. M., Feb 1 2016, In : Nature genetics. 48, 2, p. 134-143 10 p.

Research output: Contribution to journalArticle

394 Scopus citations

A Locus at 5q33.3 Confers Resistance to Tuberculosis in Highly Susceptible Individuals

Sobota, R. S., Stein, C. M., Kodaman, N., Scheinfeldt, L. B., Maro, I., Wieland-Alter, W., Igo, R. P., Magohe, A., Malone, L. L., Chervenak, K., Hall, N. B., Modongo, C., Zetola, N., Matee, M., Joloba, M., Froment, A., Nyambo, T. B., Moore, J. H., Scott, W. K., Lahey, T. & 5 others, Boom, W. H., Von Reyn, C. F., Tishkoff, S. A., Sirugo, G. & Williams, S. M., Mar 3 2016, In : American journal of human genetics. 98, 3, p. 514-524 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

Assessing the association of mitochondrial genetic variation with primary open-angle glaucoma using gene-set analyses

Khawaja, A. P., Cooke Bailey, J. N., Kang, J. H., Rand Allingham, R., Hauser, M. A., Brilliant, M., Budenz, D. L., Christen, W. G., Fingert, J., Gaasterland, D., Gaasterland, T., Kraft, P., Lee, R. K., Lichter, P. R., Liu, Y., Medeiros, F., Moroi, S. E., Richards, J. E., Realini, T., Ritch, R. & 13 others, Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Vollrath, D., Wollstein, G., Zack, D. J., Zhang, K., Pericak-Vance, M., Weinreb, R. N., Haines, J. L., Pasquale, L. R. & Wiggs, J. L., Sep 2016, In : Investigative Ophthalmology and Visual Science. 57, 11, p. 5046-5052 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

DNA variants in CACNA1C modify Parkinson disease risk only when Vitamin D level is deficient

Wang, L., Maldonado, L., Beecham, G. W., Martin, E. R., Evatt, M. L., Ritchie, J. C., Haines, J. L., Zabetian, C. P., Payami, H., Pericak-Vance, M. A., Vance, J. M. & Scott, W. K., Jun 1 2016, In : Neurology: Genetics. 2, 3, e72.

Research output: Contribution to journalArticle

5 Scopus citations

Genetic association analysis of drusen progression

Hoffman, J. D., Van Grinsven, M. J. J. P., Li, C., Brantley, M., McGrath, J., Agarwal, A., Scott, W. K., Schwartz, S. G., Kovach, J., Pericak-Vance, M., Sanchez, C. I. & Haines, J. L., Apr 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 4, p. 2225-2231 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

Bailey, J. N. C., Loomis, S. J., Kang, J. H., Allingham, R. R., Gharahkhani, P., Khor, C. C., Burdon, K. P., Aschard, H., Chasman, D. I., Igo, R. P., Hysi, P. G., Glastonbury, C. A., Ashley-Koch, A., Brilliant, M., Brown, A. A., Budenz, D. L., Buil, A., Cheng, C. Y., Choi, H., Christen, W. G. & 60 others, Curhan, G., De Vivo, I., Fingert, J. H., Foster, P. J., Fuchs, C., Gaasterland, D., Gaasterland, T., Hewitt, A. W., Hu, F., Hunter, D. J., Khawaja, A. P., Lee, R. K., Li, Z., Lichter, P. R., Mackey, D. A., McGuffin, P., Mitchell, P., Moroi, S. E., Perera, S. A., Pepper, K. W., Qi, Q., Realini, T., Richards, J. E., Ridker, P. M., Rimm, E., Ritch, R., Ritchie, M., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Song, Y. E., Tamimi, R. M., Topouzis, F., Viswanathan, A. C., Verma, S. S., Vollrath, D., Wang, J. J., Weisschuh, N., Wissinger, B., Wollstein, G., Wong, T. Y., Yaspan, B. L., Zack, D. J., Zhang, K., Weinreb, R. N., Pericak-Vance, M. A., Small, K., Hammond, C. J., Aung, T., Liu, Y., Vithana, E. N., MacGregor, S., Craig, J. E., Kraft, P., Howell, G., Hauser, M. A., Pasquale, L. R., Haines, J. L. & Wiggs, J. L., Feb 1 2016, In : Nature genetics. 48, 2, p. 189-194 6 p.

Research output: Contribution to journalArticle

105 Scopus citations

Heritability of Choroidal Thickness in the Amish

Sardell, R. J., Nittala, M. G., Adams, L. D., Laux, R. A., Cooke Bailey, J. N., Fuzzell, D., Fuzzell, S., Reinhart-Mercer, L., Caywood, L. J., Horst, V., Mackay, T., Dana, D., Sadda, S. V. R., Scott, W. K., Stambolian, D., Haines, J. L. & Pericak-Vance, M. A., Dec 1 2016, In : Ophthalmology. 123, 12, p. 2537-2544 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Linkage of familial essential tremor to chromosome 5q35

Hicks, J. E., Konidari, I., Scott, B. L., Stajich, J. M., Ashley-Koch, A. E., Gilbert, J. & Scott, W. K., Jul 1 2016, In : Movement Disorders. 31, 7, p. 1059-1062 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Overlap between Parkinson disease and Alzheimer disease in ABCA7 functional variants

Nuytemans, K., Maldonado, L., Ali, A., John-Williams, K., Beecham, G. W., Martin, E., Scott, W. K. & Vance, J. M., Feb 1 2016, In : Neurology: Genetics. 2, 1, e44.

Research output: Contribution to journalArticle

12 Scopus citations

Progression rate from intermediate to advanced age-related macular degeneration is correlated with the number of risk alleles at the CFH locus

Sardell, R. J., Persad, P. J., Pan, S. S., Whitehead, P., Adams, L. D., Laux, R. A., Fortun, J. A., Brantley, M. A., Kovach, J. L., Schwartz, S. G., Agarwal, A., Haines, J. L., Scott, W. K. & Pericak-Vance, M. A., Nov 2016, In : Investigative Ophthalmology and Visual Science. 57, 14, p. 6107-6115 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Whole exome sequencing of extreme age-related macular degeneration phenotypes

Sardell, R. J., Bailey, J. N. C., Courtenay, M. D., Whitehead, P., Laux, R. A., Adams, L. D., Fortun, J., Brantley, M. A., Kovach, J., Schwartz, S., Agarwal, A., Scott, W. K., Haines, J. L. & Pericak-Vance, M. A., Aug 29 2016, In : Molecular Vision. 22, p. 1062-1076 15 p.

Research output: Contribution to journalArticle

9 Scopus citations
2015

Estimating cumulative pathway effects on risk for age-related macular degeneration using mixed linear models

Hall, J. B., Cooke Bailey, J. N., Hoffman, J. D., Pericak-Vance, M. A., Scott, W. K., Kovach, J. L., Schwartz, S. G., Agarwal, A., Brantley, M. A., Haines, J. L. & Bush, W. S., Oct 14 2015, In : BMC Bioinformatics. 16, 1, 329.

Research output: Contribution to journalArticle

7 Scopus citations

Examination of candidate exonic variants for association to alzheimer disease in the Amish

D'Aoust, L. N., Cummings, A. C., Laux, R., Fuzzell, D., Caywood, L., Reinhart-Mercer, L., Scott, W. K., Pericak-Vance, M. A. & Haines, J. L., Feb 10 2015, In : PloS one. 10, 2, e0118043.

Research output: Contribution to journalArticle

4 Scopus citations

Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology

NEIGHBORHOOD Consortium, Mar 1 2015, In : Genetic Epidemiology. 39, 3, p. 207-216 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease

Beecham, G. W., Dickson, D. W., Scott, W. K., Martin, E. R., Schellenberg, G., Nuytemans, K., Larson, E. B., Buxbaum, J. D., Trojanowski, J. Q., Van Deerlin, V. M., Hurtig, H. I., Mash, D. C., Beach, T. G., Troncoso, J. C., Pletnikova, O., Frosch, M. P., Ghetti, B., Foroud, T. M., Honig, L. S., Marder, K. & 12 others, Vonsattel, J. P., Goldman, S. M., Vinters, H. V., Ross, O. A., Wszolek, Z. K., Wang, L., Dykxhoorn, D. M., Pericak-Vance, M. A., Montine, T. J., Leverenz, J. B., Dawson, T. M. & Vance, J. M., Mar 10 2015, In : Neurology. 84, 10, p. 972-980 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Polymorphisms in HLA class II genes are associated with susceptibility to staphylococcus aureus infection in a white population

DeLorenze, G. N., Nelson, C. L., Scott, W. K., Allen, A. S., Ray, G. T., Tsai, A. L., Quesenberry, C. P. & Fowler, V. G., Jan 1 2015, In : Journal of Infectious Diseases. 212, 11, p. 816-823 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

The relationship between obsessive-compulsive symptoms and PARKIN genotype: The CORE-PD study

Sharp, M. E., Caccappolo, E., Mejia-Santana, H., Tang, M. X., Rosado, L., Orbe Reilly, M., Ruiz, D., Louis, E. D., Comella, C., Nance, M., Bressman, S., Scott, W. K., Tanner, C., Waters, C., Fahn, S., Cote, L., Ford, B., Rezak, M., Novak, K., Friedman, J. H. & 12 others, Pfeiffer, R., Payami, H., Molho, E., Factor, S. A., Nutt, J., Serrano, C., Arroyo, M., Pauciulo, M. W., Nichols, W. C., Clark, L. N., Alcalay, R. N. & Marder, K. S., Feb 1 2015, In : Movement Disorders. 30, 2, p. 278-283 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

The Relationship Between Reticular Pseudodrusen and Severity of AMD

Kovach, J., Schwartz, S., Agarwal, A., Brantley, M. A., Pan, S. S., Haines, J. L., Scott, W. K. & Pericak-Vance, M. A., Oct 6 2015, (Accepted/In press) In : Ophthalmology.

Research output: Contribution to journalArticle

10 Scopus citations

Vitamin D from different sources is inversely associated with Parkinson disease

Wang, L., Evatt, M. L., Maldonado, L. G., Perry, W. R., Ritchie, J. C., Beecham, G. W., Martin, E. R., Haines, J. L., Pericak-Vance, M. A., Vance, J. M. & Scott, W. K., Apr 1 2015, In : Movement Disorders. 30, 4, p. 560-566 7 p.

Research output: Contribution to journalArticle

31 Scopus citations
2013

C9orf72 intermediate repeat copies are a significant risk factor for parkinson disease

Nuytemans, K., Bademci, G., Kohli, M. M., Beecham, G. W., Wang, L., Young, J. I., Nahab, F., Martin, E. R., Gilbert, J. R., Benatar, M., Haines, J. L., Scott, W. K., Züchner, S., Pericak-Vance, M. A. & Vance, J. M., Sep 2013, In : Annals of Human Genetics. 77, 5, p. 351-363 13 p.

Research output: Contribution to journalArticle

46 Scopus citations

Coding variants in ARMS2 and the risk of age-related macular degeneration

Wang, G., Scott, W. K., Agarwal, A., Haines, J. L. & Pericak-Vance, M. A., Jun 1 2013, In : JAMA ophthalmology. 131, 6, p. 804-805 2 p.

Research output: Contribution to journalLetter

6 Scopus citations

Estrogen pathway polymorphisms in relation to primary open angle glaucoma: An analysis accounting for gender from the United States

Pasquale, L. R., Loomis, S. J., Weinreb, R. N., Kang, J. H., Yaspan, B. L., Cooke Bailey, J., Gaasterland, D., Gaasterland, T., Lee, R. K., Scott, W. K., Lichter, P. R., Budenz, D. L., Liu, Y., Realini, T., Friedman, D. S., McCarty, C. A., Moroi, S. E., Olson, L., Schuman, J. S., Singh, K. & 15 others, Vollrath, D., Wollstein, G., Zack, D. J., Brilliant, M., Sit, A. J., Christen, W. G., Fingert, J., Kraft, P., Zhang, K., Allingham, R. R., Pericak-Vance, M. A., Richards, J. E., Hauser, M. A., Haines, J. L. & Wiggs, J. L., Jul 12 2013, In : Molecular vision. 19, p. 1471-1481 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Evaluating Power and Type 1 Error in Large Pedigree Analyses of Binary Traits

Cummings, A. C., Torstenson, E., Davis, M. F., D'Aoust, L. N., Scott, W. K., Pericak-Vance, M. A., Bush, W. S. & Haines, J. L., May 3 2013, In : PloS one. 8, 5, e62615.

Research output: Contribution to journalArticle

4 Scopus citations

Functional genomics identifies type i interferon pathway as central for host defense against Candida albicans

Smeekens, S. P., Ng, A., Kumar, V., Johnson, M. D., Plantinga, T. S., Van Diemen, C., Arts, P., Verwiel, E. T. P., Gresnigt, M. S., Fransen, K., Van Sommeren, S., Oosting, M., Cheng, S. C., Joosten, L. A. B., Hoischen, A., Kullberg, B. J., Scott, W. K., Perfect, J. R., Van Der Meer, J. W. M., Wijmenga, C. & 2 others, Netea, M. G. & Xavier, R. J., 2013, In : Nature communications. 4, 1342.

Research output: Contribution to journalArticle

93 Scopus citations

Genetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis

Naj, A. C., Scott, W. K., Courtenay, M. D., Cade, W. H., Schwartz, S. G., Kovach, J. L., Agarwal, A., Wang, G., Haines, J. L. & Pericak-Vance, M. A., May 1 2013, In : Annals of Human Genetics. 77, 3, p. 215-231 17 p.

Research output: Contribution to journalArticle

29 Scopus citations
12 Scopus citations

Linkage and association of successful aging to the 6q25 region in large Amish kindreds

Edwards, D. R. V., Gilbert, J. R., Hicks, J. E., Myers, J. L., Jiang, L., Cummings, A. C., Guo, S., Gallins, P. J., Konidari, I., Caywood, L., Reinhart-Mercer, L., Fuzzell, D., Knebusch, C., Laux, R., Jackson, C. E., Pericak-Vance, M. A., Haines, J. L. & Scott, W. K., Aug 1 2013, In : AGE. 35, 4, p. 1467-1477 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Parkinson disease loci in the mid-western Amish

Davis, M. F., Cummings, A. C., D'Aoust, L. N., Jiang, L., Velez Edwards, D. R., Laux, R., Reinhart-Mercer, L., Fuzzell, D., Scott, W. K., Pericak-Vance, M. A., Lee, S. L. & Haines, J. L., Nov 1 2013, In : Human genetics. 132, 11, p. 1213-1221 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Seven new loci associated with age-related macular degeneration

Fritsche, L. G., Chen, W., Schu, M., Yaspan, B. L., Yu, Y., Thorleifsson, G., Zack, D. J., Arakawa, S., Cipriani, V., Ripke, S., Igo, R. P., Buitendijk, G. H. S., Sim, X., Weeks, D. E., Guymer, R. H., Merriam, J. E., Francis, P. J., Hannum, G., Agarwal, A., Armbrecht, A. M. & 136 others, Audo, I., Aung, T., Barile, G. R., Benchaboune, M., Bird, A. C., Bishop, P. N., Branham, K. E., Brooks, M., Brucker, A. J., Cade, W. H., Cain, M. S., Campochiaro, P. A., Chan, C. C., Cheng, C. Y., Chew, E. Y., Chin, K. A., Chowers, I., Clayton, D. G., Cojocaru, R., Conley, Y. P., Cornes, B. K., Daly, M. J., Dhillon, B., Edwards, A. O., Evangelou, E., Fagerness, J., Ferreyra, H. A., Friedman, J. S., Geirsdottir, A., George, R. J., Gieger, C., Gupta, N., Hagstrom, S. A., Harding, S. P., Haritoglou, C., Heckenlively, J. R., Holz, F. G., Hughes, G., Ioannidis, J. P. A., Ishibashi, T., Joseph, P., Jun, G., Kamatani, Y., Katsanis, N., N Keilhauer, C., Khan, J. C., Kim, I. K., Kiyohara, Y., Klein, B. E. K., Klein, R., Kovach, J. L., Kozak, I., Lee, C. J., Lee, K. E., Lichtner, P., Lotery, A. J., Meitinger, T., Mitchell, P., Mohand-Saïd, S., Moore, A. T., Morgan, D. J., Morrison, M. A., Myers, C. E., Naj, A. C., Nakamura, Y., Okada, Y., Orlin, A., Ortube, M. C., Othman, M. I., Pappas, C., Park, K. H., Pauer, G. J. T., Peachey, N. S., Poch, O., Priya, R. R., Reynolds, R., Richardson, A. J., Ripp, R., Rudolph, G., Ryu, E., Sahel, J. A., Schaumberg, D. A., Scholl, H. P. N., Schwartz, S. G., Scott, W. K., Shahid, H., Sigurdsson, H., Silvestri, G., Sivakumaran, T. A., Smith, R. T., Sobrin, L., Souied, E. H., Stambolian, D. E., Stefansson, H., Sturgill-Short, G. M., Takahashi, A., Tosakulwong, N., Truitt, B. J., Tsironi, E. E., Uitterlinden, A. G., Van Duijn, C. M., Vijaya, L., Vingerling, J. R., Vithana, E. N., Webster, A. R., Wichmann, H. E., Winkler, T. W., Wong, T. Y., Wright, A. F., Zelenika, D., Zhang, M., Zhao, L., Zhang, K., Klein, M. L., Hageman, G. S., Lathrop, G. M., Stefansson, K., Allikmets, R., Baird, P. N., Gorin, M. B., Wang, J. J., Klaver, C. C. W., Seddon, J. M., Pericak-Vance, M. A., Iyengar, S. K., Yates, J. R. W., Swaroop, A., Weber, B. H. F., Kubo, M., Deangelis, M. M., Léveillard, T., Thorsteinsdottir, U., Haines, J. L., Farrer, L. A., Heid, I. M. & Abecasis, G. R., Apr 2013, In : Nature genetics. 45, 4, p. 433-439 7 p.

Research output: Contribution to journalArticle

483 Scopus citations

Variants at chromosome 10q26 locus and the expression of HTRA1 in the retina

Wang, G., Dubovy, S. R., Kovach, J. L., Schwartz, S. G., Agarwal, A., Scott, W. K., Haines, J. L. & Pericak-Vance, M. A., Jul 1 2013, In : Experimental Eye Research. 112, p. 102-105 4 p.

Research output: Contribution to journalArticle

15 Scopus citations

Whole exome sequencing of rare variants in EIF4G1 and VPS35 in Parkinson disease

Nuytemans, K., Bademci, G., Inchausti, V., Dressen, A., Kinnamon, D. D., Mehta, A., Wang, L., Züchner, S., Beecham, G. W., Martin, E. R., Scott, W. K. & Vance, J. M., Mar 12 2013, In : Neurology. 80, 11, p. 982-989 8 p.

Research output: Contribution to journalArticle

51 Scopus citations
2012

A novel ARMS2 splice variant is identified in human retina

Wang, G., Scott, W. K., Whitehead, P., Court, B. L., Kovach, J. L., Schwartz, S. G., Agarwal, A., Dubovy, S., Haines, J. L. & Pericak-Vance, M. A., Jan 1 2012, In : Experimental Eye Research. 94, 1, p. 187-191 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Cognitive performance of GBA mutation carriers with early-onset PD The CORE-PD study

Alcalay, R. N., Caccappolo, E., Mejia-Santana, H., Tang, M. X., Rosado, L., Reilly, M. O., Ruiz, D., Ross, B., Verbitsky, M., Kisselev, S., Louis, E., Comella, C., Colcher, A., Jennings, D., Nance, M., Bressman, S., Scott, W. K., Tanner, C., Mickel, S., Andrews, H. & 18 others, Waters, C., Fahn, S., Cote, L., Frucht, S., Ford, B., Rezak, M., Novak, K., Friedman, J. H., Pfeiffer, R., Marsh, L., Hiner, B., Siderowf, A., Payami, H., Molho, E., Factor, S., Ottman, R., Clark, L. N. & Marder, K., May 1 2012, In : Neurology. 78, 18, p. 1434-1440 7 p.

Research output: Contribution to journalArticle

140 Scopus citations

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDgene database

Lill, C. M., Roehr, J. T., McQueen, M. B., Kavvoura, F. K., Bagade, S., Schjeide, B. M. M., Schjeide, L. M., Meissner, E., Zauft, U., Allen, N. C., Liu, T., Schilling, M., Anderson, K. J., Beecham, G., Berg, D., Biernacka, J. M., Brice, A., DeStefano, A. L., Do, C. B., Eriksson, N. & 34 others, Factor, S. A., Farrer, M. J., Foroud, T., Gasser, T., Hamza, T., Hardy, J. A., Heutink, P., Hill-Burns, E. M., Klein, C., Latourelle, J. C., Maraganore, D. M., Martin, E. R., Martinez, M., Myers, R. H., Nalls, M. A., Pankratz, N., Payami, H., Satake, W., Scott, W. K., Sharma, M., Singleton, A. B., Stefansson, K., Toda, T., Tung, J. Y., Vance, J., Wood, N. W., Zabetian, C. P., Young, P., Tanzi, R. E., Khoury, M. J., Zipp, F., Lehrach, H., Ioannidis, J. P. A. & Bertram, L., Mar 2012, In : PLoS genetics. 8, 3, e1002548.

Research output: Contribution to journalArticle

367 Scopus citations

Cytokine gene polymorphisms and the outcome of invasive candidiasis: A prospective cohort study

Johnson, M. D., Plantinga, T. S., Van De Vosse, E., Velez Edwards, D. R., Smith, P. B., Alexander, B. D., Yang, J. C., Kremer, D., Laird, G. M., Oosting, M., Joosten, L. A. B., Van Der Meer, J. W. M., Van Dissel, J. T., Walsh, T. J., Perfect, J. R., Kullberg, B. J., Scott, W. K. & Netea, M. G., Feb 15 2012, In : Clinical Infectious Diseases. 54, 4, p. 502-510 9 p.

Research output: Contribution to journalArticle

49 Scopus citations

Genome-Wide Association and Linkage Study in the Amish Detects a Novel Candidate Late-Onset Alzheimer Disease Gene

Cummings, A. C., Jiang, L., Velez Edwards, D. R., Mccauley, J. L., Laux, R., Mcfarland, L. L., Fuzzell, D., Knebusch, C., Caywood, L., Reinhart-Mercer, L., Nations, L., Gilbert, J. R., Konidari, I., Tramontana, M., Cuccaro, M. L., Scott, W. K., Pericak-Vance, M. A. & Haines, J. L., Sep 1 2012, In : Annals of Human Genetics. 76, 5, p. 342-351 10 p.

Research output: Contribution to journalArticle

21 Scopus citations