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  • William K Scott
2020

A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration

International AMD Genomics Consortium (IAMDGC), Dec 1 2020, In : Scientific reports. 10, 1, 1584.

Research output: Contribution to journalArticle

Open Access
2019

AMISH EYE STUDY: Baseline Spectral Domain Optical Coherence Tomography Characteristics of Age-Related Macular Degeneration

Nittala, M. G., Song, Y. E., Sardell, R., Adams, L. D., Pan, S., Velaga, S. B., Horst, V., Dana, D., Caywood, L., Laux, R., Fuzzell, D., Fuzzell, S., Scott, W. K., Cooke Bailey, J. N., Igo, R. P., Haines, J., Pericak-Vance, M. A., Sadda, S. R. & Stambolian, D., Aug 1 2019, In : Retina. 39, 8, p. 1540-1550 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Association of a Primary Open-Angle Glaucoma Genetic Risk Score with Earlier Age at Diagnosis

Fan, B. J., Bailey, J. C., Igo, R. P., Kang, J. H., Boumenna, T., Brilliant, M. H., Budenz, D. L., Fingert, J. H., Gaasterland, T., Gaasterland, D., Hauser, M. A., Kraft, P., Lee, R. K., Lichter, P. R., Liu, Y., Moroi, S. E., Myers, J. S., Pericak-Vance, M. A., Realini, A., Rhee, D. J. & 13 others, Richards, J. E., Ritch, R., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Vollrath, D., Weinreb, R. N., Wollstein, G., Zack, D. J., Haines, J. L., Pasquale, L. R. & Wiggs, J. L., Oct 2019, In : JAMA ophthalmology. 137, 10, p. 1190-1194 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Erratum to: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases (Nature Communications, (2018), 9, 1, (1864), 10.1038/s41467-018-03646-6)

Blue Mountains Eye Study - GWAS group, Wellcome Trust Case Control Consortium 2 (WTCCC2) & NEIGHBORHOOD Consortium, Dec 1 2019, In : Nature communications. 10, 1, 155.

Research output: Contribution to journalComment/debate

Open Access

Genome-wide brain DNA methylation analysis suggests epigenetic reprogramming in Parkinson disease

Young, J. I., Sivasankaran, S. K., Wang, L., Ali, A., Mehta, A., Davis, D. A., Dykxhoorn, D. M., Petito, C. K., Beecham, G. W., Martin, E. R., Mash, D. C., Pericak-Vance, M., Scott, W. K., Montine, T. J. & Vance, J. M., Aug 1 2019, In : Neurology: Genetics. 5, 4, 342.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Motivations for participation in Parkinson disease genetic research among hispanics versus non-hispanics

Nuytemans, K., Manrique, C. P., Uhlenberg, A., Scott, W. K., Cuccaro, M. L., Luca, C., Singer, C. & Vance, J. M., Jan 1 2019, In : Frontiers in Genetics. 10, JUN, 658.

Research output: Contribution to journalComment/debate

Open Access

Multi-trait genome-wide association study identifies new loci associated with optic disc parameters

International Glaucoma Genetics Consortium, NEIGHBORHOOD Consortium & UK Biobank Eye and Vision Consortium, Dec 1 2019, In : Communications Biology. 2, 1, 435.

Research output: Contribution to journalArticle

Open Access

Rare variants and loci for age-related macular degeneration in the Ohio and Indiana Amish

Waksmunski, A. R., Igo, R. P., Song, Y. E., Cooke Bailey, J. N., Laux, R., Fuzzell, D., Fuzzell, S., Adams, L. D., Caywood, L., Prough, M., Stambolian, D., Scott, W. K., Pericak-Vance, M. A. & Haines, J. L., Oct 1 2019, In : Human genetics. 138, 10, p. 1171-1182 12 p.

Research output: Contribution to journalArticle

Open Access
2018

Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma

Gharahkhani, P., Burdon, K. P., Cooke Bailey, J. N., Hewitt, A. W., Law, M. H., Pasquale, L. R., Kang, J. H., Haines, J. L., Souzeau, E., Zhou, T., Siggs, O. M., Landers, J., Awadalla, M., Sharma, S., Mills, R. A., Ridge, B., Lynn, D., Casson, R., Graham, S. L., Goldberg, I. & 45 others, White, A., Healey, P. R., Grigg, J., Lawlor, M., Mitchell, P., Ruddle, J., Coote, M., Walland, M., Best, S., Vincent, A., Gale, J., Radfordsmith, G., Whiteman, D. C., Montgomery, G. W., Martin, N. G., MacKey, D. A., Wiggs, J. L., MacGregor, S., Craig, J. E., Allingham, R. R., Brilliant, M., Budenz, D. L., Fingert, J. H., Gaasterland, D., Gaasterland, T., Hark, L., Hauser, M., Igo, R. P., Kraft, P., Lee, R. K., Lichter, P. R., Liu, Y., Moroi, S., Pericak-Vance, M., Realini, A., Rhee, D., Richards, J. E., Ritch, R., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Vollrath, D., Wollstein, G. & Zack, D. J., Dec 1 2018, In : Scientific reports. 8, 1, 3124.

Research output: Contribution to journalArticle

6 Scopus citations

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases

Iglesias, A. I., Mishra, A., Vitart, V., Bykhovskaya, Y., Höhn, R., Springelkamp, H., Cuellar-Partida, G., Gharahkhani, P., Bailey, J. N. C., Willoughby, C. E., Li, X., Yazar, S., Nag, A., Khawaja, A. P., Polašek, O., Siscovick, D., Mitchell, P., Tham, Y. C., Haines, J. L., Kearns, L. S. & 124 others, Hayward, C., Shi, Y., Van Leeuwen, E. M., Taylor, K. D., Wang, J. J., Rochtchina, E., Attia, J., Scott, R., Holliday, E. G., Baird, P. N., Xie, J., Inouye, M., Viswanathan, A., Sim, X., Bonnemaijer, P., Rotter, J. I., Martin, N. G., Zeller, T., Mills, R. A., Staffieri, S. E., Jonas, J. B., Schmidtmann, I., Boutin, T., Kang, J. H., Lucas, S. E. M., Wong, T. Y., Beutel, M. E., Wilson, J. F., Allingham, R. R., Brilliant, M. H., Budenz, D. L., Christen, W. G., Fingert, J., Friedman, D. S., Gaasterland, D., Gaasterland, T., Hauser, M. A., Kraft, P., Lee, R. K., Lichter, P. R., Liu, Y., Loomis, S. J., Moroi, S. E., Pericak-Vance, M. A., Realini, A., Richards, J. E., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Vollrath, D., Weinreb, R. N., Wollstein, G., Zack, D. J., Zhang, K., Donnelly, P., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Deloukas, P., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S. J., Trembath, R. C., Wood, N. W., Spencer, C. C. A., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Pirinen, M., Pearson, R., Strange, A., Su, Z., Vukcevic, D., Langford, C., Hunt, S. E., Edkins, S., Gwilliam, R., Blackburn, H., Bumpstead, S. J., Dronov, S., Gillman, M., Gray, E., Hammond, N., Jayakumar, A., McCann, O. T., Liddle, J., Potter, S. C., Ravindrarajah, R., Ricketts, M., Waller, M., Weston, P., Widaa, S., Whittaker, P., Uitterlinden, A. G., Vithana, E. N., Foster, P. J., Hysi, P. G., Hewitt, A. W., Khor, C. C., Pasquale, L. R., Montgomery, G. W., Klaver, C. C. W., Aung, T., Pfeiffer, N., MacKey, D. A., Hammond, C. J., Cheng, C. Y., Craig, J. E., Rabinowitz, Y. S., Wiggs, J. L., Burdon, K. P., Van Duijn, C. M. & MacGregor, S., Dec 1 2018, In : Nature communications. 9, 1, 1864.

Research output: Contribution to journalArticle

9 Scopus citations

Erratum: Author Correction: A population-specific reference panel empowers genetic studies of Anabaptist populations (Scientific reports (2017) 7 1 (6079))

Hou, L., Kember, R. L., Roach, J. C., O'Connell, J. R., Craig, D. W., Bucan, M., Scott, W. K., Pericak-Vance, M., Haines, J. L., Crawford, M. H., Shuldiner, A. R. & McMahon, F. J., Apr 25 2018, In : Scientific reports. 8, 1, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Family-based genome-wide association study of south Indian pedigrees supports WNT7B as a central corneal thickness locus

Fan, B. J., Chen, X., Sondhi, N., Sharmila, P. F., Soumittra, N., Sripriya, S., Sacikala, S., Asokan, R., Friedman, D. S., Pasquale, L. R., Gao, X. R., Vijaya, L., Bailey, J. C., Vitart, V., Macgregor, S., Hammond, C. J., Khor, C. C., Haines, J. L., George, R., Wiggs, J. L. & 56 others, Allingham, R. R., Gauderman, J., Hauser, M., Rotter, J. I., Varma, R., Aung, T., Burdon, K. P., Cheng, C. Y., Craig, J. E., Cree, A. J., Gharahkhani, P., Hewitt, A. W., Höhn, R., Hysi, P., Iglesias Gonzalez, A. I., Jonas, J., Khawaja, A., Klaver, C. C. W., Pasutto, F., Mackey, D., Mitchell, P., Mishra, A., Pang, C., Springelkamp, H., Thorleifsson, G., Thorsteinsdottir, U., van Duijn, C. M., Viswanathan, A., Wojciechowski, R., Wong, T., Young, T. L., Zeller, T., Brilliant, M., Budenz, D., Fingert, J., Gaasterland, D., Gaasterland, T., Igo, R., Kang, J. H., Kraft, P., Lee, R., Lichter, P., Liu, Y., Moroi, S., Realini, A., Rhee, D., Richards, J. R., Ritch, R., Schuman, J., Scott, W. K., Singh, K., Sit, A., Vollrath, D., Weinreb, R. N., Wollstein, G. & Zack, D., May 1 2018, In : Investigative Ophthalmology and Visual Science. 59, 6, p. 2495-2502 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease

Hui, K. Y., Fernandez-Hernandez, H., Hu, J., Schaffner, A., Pankratz, N., Hsu, N. Y., Chuang, L. S., Carmi, S., Villaverde, N., Li, X., Rivas, M., Levine, A. P., Bao, X., Labrias, P. R., Haritunians, T., Ruane, D., Gettler, K., Chen, E., Li, D., Schiff, E. R. & 31 others, Pontikos, N., Barzilai, N., Brant, S. R., Bressman, S., Cheifetz, A. S., Clark, L. N., Daly, M. J., Desnick, R. J., Duerr, R. H., Katz, S., Lencz, T., Myers, R. H., Ostrer, H., Ozelius, L., Payami, H., Peter, Y., Rioux, J. D., Segal, A. W., Scott, W. K., Silverberg, M. S., Vance, J. M., Ubarretxena-Belandia, I., Foroud, T., Atzmon, G., Pe'er, I., Ioannou, Y., McGovern, D. P. B., Yue, Z., Schadt, E. E., Cho, J. H. & Peter, I., Jan 10 2018, In : Science Translational Medicine. 10, 423, eaai7795.

Research output: Contribution to journalArticle

67 Scopus citations

Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma

International Glaucoma Genetics Consortium & NEIGHBORHOOD Consortium, Jan 1 2018, In : PLoS genetics. 14, 1, e1007145.

Research output: Contribution to journalArticle

7 Scopus citations

Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia

Scott, W. K., Medie, F. M., Ruffin, F., Sharma-Kuinkel, B. K., Cyr, D. D., Guo, S., Dykxhoorn, D. M., Skov, R. L., Bruun, N. E., Dahl, A., Lerche, C. J., Petersen, A., Larsen, A. R., Lauridsen, T. K., Johansen, H. K., Ullum, H., Sørensen, E., Hassager, C., Bundgaard, H., Schønheyder, H. C. & 9 others, Torp-Pedersen, C., Østergaard, L. B., Arpi, M., Rosenvinge, F., Erikstrup, L. T., Chehri, M., Søgaard, P., Andersen, P. S. & Fowler, V. G., Oct 2018, In : PLoS genetics. 14, 10, e1007667.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Testosterone pathway genetic polymorphisms in relation to primary open-angle glaucoma: An analysis in two large datasets

Australian and New Zealand Registry of Advanced Glaucoma (ANZRAG) Consortium, Feb 2018, In : Investigative Ophthalmology and Visual Science. 59, 2, p. 629-636 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

The carnitine shuttle pathway is altered in patients with neovascular age-related macular degeneration

Mitchell, S. L., Uppal, K., Williamson, S. M., Liu, K., Goodwin Burgess, L., Tran, V., Umfress, A. C., Jarrell, K. L., Cooke Bailey, J. N., Agarwal, A., Pericak-Vance, M., Haines, J. L., Scott, W. K., Jones, D. P. & Brantley, M. A., Oct 1 2018, In : Investigative Ophthalmology and Visual Science. 59, 12, p. 4978-4985 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
2017

A chromosome 5q31.1 locus associates with tuberculin skin test reactivity in HIV-positive individuals from tuberculosis hyper-endemic regions in east Africa

Sobota, R. S., Stein, C. M., Kodaman, N., Maro, I., Wieland-Alter, W., Igo, R. P., Magohe, A., Malone, L. S. L., Chervenak, K., Hall, N. B., Matee, M., Mayanja-Kizza, H., Joloba, M., Moore, J. H., Scott, W. K., Lahey, T., Boom, W. H., von Reyn, C. F., Williams, S. M. & Sirugo, G., Jan 1 2017, In : PLoS genetics. 13, 6, e1006710.

Research output: Contribution to journalArticle

6 Scopus citations

Age at natural menopause genetic risk score in relation to age at natural menopause and primary open-angle glaucoma in a US-based sample

Pasquale, L. R., Aschard, H., Kang, J. H., Bailey, J. N. C., Lindström, S., Chasman, D. I., Christen, W. G., Allingham, R. R., Ashley-Koch, A., Lee, R. K., Moroi, S. E., Brilliant, M. H., Wollstein, G., Schuman, J. S., Fingert, J., Budenz, D. L., Realini, T., Gaasterland, T., Gaasterland, D., Scott, W. K. & 21 others, Singh, K., Sit, A. J., Igo, R. P., Song, Y. E., Hark, L., Ritch, R., Rhee, D. J., Gulati, V., Havens, S., Vollrath, D., Zack, D. J., Medeiros, F., Weinreb, R. N., Pericak-Vance, M. A., Liu, Y., Kraft, P., Richards, J. E., Rosner, B. A., Hauser, M. A., Haines, J. L. & Wiggs, J. L., Jan 1 2017, In : Menopause. 24, 2, p. 150-156 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

A population-specific reference panel empowers genetic studies of Anabaptist populations

Hou, L., Kember, R. L., Roach, J. C., O'Connell, J. R., Craig, D. W., Bucan, M., Scott, W. K., Pericak-Vance, M. A., Haines, J. L., Crawford, M. H., Shuldiner, A. R. & McMahon, F. J., Dec 1 2017, In : Scientific Reports. 7, 1, 6079.

Research output: Contribution to journalArticle

5 Scopus citations

Candidate genes on murine chromosome 8 are associated with susceptibility to Staphylococcus aureus infection in mice and are involved with Staphylococcus aureus septicemia in humans

Yan, Q., Ahn, S. H., Medie, F. M., Sharma-Kuinkel, B. K., Park, L. P., Scott, W. K., Deshmukh, H., Tsalik, E. L., Cyr, D. D., Woods, C. W., Yu, C. H. A., Adams, C., Qi, R., Hansen, B. & Fowler, V. G., Jun 2017, In : PloS one. 12, 6, e0179033.

Research output: Contribution to journalArticle

2 Scopus citations

Evaluating genetic susceptibility to Staphylococcus aureus bacteremia in African Americans using admixture mapping

Cyr, D. D., Allen, A. S., Du, G. J., Ruffin, F., Adams, C., Thaden, J. T., Maskarinec, S. A., Souli, M., Guo, S., Dykxhoorn, D. M., Scott, W. K. & Fowler, V. G., Mar 23 2017, (Accepted/In press) In : Genes and Immunity.

Research output: Contribution to journalArticle

10 Scopus citations

Generation of disease-specific autopsy-confirmed iPSCs lines from postmortem isolated Peripheral Blood Mononuclear Cells

Belle, K., Shabazz, F. S., Nuytemans, K., Davis, D. A., Ali, A., Young, J., Scott, W. K., Mash, D. C., Vance, J. M. & Dykxhoorn, D. M., Jan 10 2017, In : Neuroscience Letters. 637, p. 201-206 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Genetic correlations between intraocular pressure, blood pressure and primary open-angle glaucoma: A multi-cohort analysis

Aschard, H., Kang, J. H., Iglesias, A. I., Hysi, P., Cooke Bailey, J. N., Khawaja, A. P., Allingham, R. R., Ashley-Koch, A., Lee, R. K., Moroi, S. E., Brilliant, M. H., Wollstein, G., Schuman, J. S., Fingert, J. H., Budenz, D. L., Realini, T., Gaasterland, T., Scott, W. K., Singh, K., Sit, A. J. & 25 others, Igo, R. P., Song, Y. E., Hark, L., Ritch, R., Rhee, D. J., Gulati, V., Haven, S., Vollrath, D., Zack, D. J., Medeiros, F., Weinreb, R. N., Cheng, C. Y., Chasman, D. I., Christen, W. G., Pericak-Vance, M. A., Liu, Y., Kraft, P., Richards, J. E., Rosner, B. A., Hauser, M. A., Klaver, C. C. W., Vanduijn, C. M., Haines, J., Wiggs, J. L. & Pasquale, L. R., Nov 1 2017, In : European Journal of Human Genetics. 25, 11, p. 1261-1267 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits

International AMD Genomics Consortium (IAMDGC), Mar 27 2017, In : Genome Medicine. 9, 1, 29.

Research output: Contribution to journalArticle

27 Scopus citations

Joint Analysis of Nuclear and Mitochondrial Variants in Age-Related Macular Degeneration Identifies Novel Loci TRPM1 and ABHD2/RLBP1

for the International Age-Related Macular Degeneration Genomics Consortium (IAMDGC), Aug 1 2017, In : Investigative ophthalmology & visual science. 58, 10, p. 4027-4038 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Recombinant haplotypes narrow the ARMS2/HTRA1 association signal for age-related macular degeneration

International AMD Genomics Consortium (IAMDGC), Feb 2017, In : Genetics. 205, 2, p. 919-924 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility

Chintalapudi, S. R., Maria, D., Di Wang, X., Bailey, J. N. C., Allingham, R., Brilliant, M., Budenz, D., Fingert, J., Gaasterland, D., Gaasterland, T., Haines, J. L., Hark, L., Hauser, M., Igo, R., Hee Kang, J., Kraft, P., Lee, R., Lichter, P., Liu, Y., Moroi, S. & 43 others, Pasquale, L. R., Pericak-Vance, M., Realini, A., Rhee, D., Richards, J. R., Ritch, R., Schuman, J., Scott, W. K., Singh, K., Sit, A., Vollrath, D., Wollstein, G., Zack, D., Aung, T., Bonnemaijer, P., Cheng, C. Y., Craig, J., Van Duijn, C., Gharahkhani, P., Iglesias Gonzalez, A., Hammond, C. J., Hewitt, A., Hoehn, R., Jonansson, F., Khawaja, A., Chuen Khor, C., Klaver, C. C. W., Lotery, A., MacKey, D., MacGregor, S., Pang, C., Pasutto, F., Stefansson, K., Thorleifsson, G., Thorsteinsdottir, U., Vitart, V., Vithana, E., Young, T., Zeller, T., Hysi, P. G., Wiggs, J. L., Williams, R. W. & Jablonski, M. M., Dec 1 2017, In : Nature communications. 8, 1, 1755.

Research output: Contribution to journalArticle

6 Scopus citations
2015

Estimating cumulative pathway effects on risk for age-related macular degeneration using mixed linear models

Hall, J. B., Cooke Bailey, J. N., Hoffman, J. D., Pericak-Vance, M. A., Scott, W. K., Kovach, J. L., Schwartz, S. G., Agarwal, A., Brantley, M. A., Haines, J. L. & Bush, W. S., Oct 14 2015, In : BMC Bioinformatics. 16, 1

Research output: Contribution to journalArticle

7 Scopus citations

Examination of candidate exonic variants for association to alzheimer disease in the Amish

D'Aoust, L. N., Cummings, A. C., Laux, R., Fuzzell, D., Caywood, L., Reinhart-Mercer, L., Scott, W. K., Pericak-Vance, M. A. & Haines, J. L., Feb 10 2015, In : PLoS One. 10, 2, e0118043.

Research output: Contribution to journalArticle

4 Scopus citations

Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology

NEIGHBORHOOD Consortium, Mar 1 2015, In : Genetic Epidemiology. 39, 3, p. 207-216 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease

Beecham, G. W., Dickson, D. W., Scott, W. K., Martin, E. R., Schellenberg, G., Nuytemans, K., Larson, E. B., Buxbaum, J. D., Trojanowski, J. Q., Van Deerlin, V. M., Hurtig, H. I., Mash, D. C., Beach, T. G., Troncoso, J. C., Pletnikova, O., Frosch, M. P., Ghetti, B., Foroud, T. M., Honig, L. S., Marder, K. & 12 others, Vonsattel, J. P., Goldman, S. M., Vinters, H. V., Ross, O. A., Wszolek, Z. K., Wang, L., Dykxhoorn, D. M., Pericak-Vance, M. A., Montine, T. J., Leverenz, J. B., Dawson, T. M. & Vance, J. M., Mar 10 2015, In : Neurology. 84, 10, p. 972-980 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Polymorphisms in HLA class II genes are associated with susceptibility to staphylococcus aureus infection in a white population

DeLorenze, G. N., Nelson, C. L., Scott, W. K., Allen, A. S., Ray, G. T., Tsai, A. L., Quesenberry, C. P. & Fowler, V. G., Jan 1 2015, In : Journal of Infectious Diseases. 212, 11, p. 816-823 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

The relationship between obsessive-compulsive symptoms and PARKIN genotype: The CORE-PD study

Sharp, M. E., Caccappolo, E., Mejia-Santana, H., Tang, M. X., Rosado, L., Orbe Reilly, M., Ruiz, D., Louis, E. D., Comella, C., Nance, M., Bressman, S., Scott, W. K., Tanner, C., Waters, C., Fahn, S., Cote, L., Ford, B., Rezak, M., Novak, K., Friedman, J. H. & 12 others, Pfeiffer, R., Payami, H., Molho, E., Factor, S. A., Nutt, J., Serrano, C., Arroyo, M., Pauciulo, M. W., Nichols, W. C., Clark, L. N., Alcalay, R. N. & Marder, K. S., Feb 1 2015, In : Movement Disorders. 30, 2, p. 278-283 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

The Relationship Between Reticular Pseudodrusen and Severity of AMD

Kovach, J., Schwartz, S., Agarwal, A., Brantley, M. A., Pan, S. S., Haines, J. L., Scott, W. K. & Pericak-Vance, M. A., Oct 6 2015, (Accepted/In press) In : Ophthalmology.

Research output: Contribution to journalArticle

10 Scopus citations

Vitamin D from different sources is inversely associated with Parkinson disease

Wang, L., Evatt, M. L., Maldonado, L. G., Perry, W. R., Ritchie, J. C., Beecham, G. W., Martin, E. R., Haines, J. L., Pericak-Vance, M. A., Vance, J. M. & Scott, W. K., Apr 1 2015, In : Movement Disorders. 30, 4, p. 560-566 7 p.

Research output: Contribution to journalArticle

30 Scopus citations
2014

Absence of C9ORF72 expanded or intermediate repeats in autopsy-confirmed Parkinson's disease

Nuytemans, K., Inchausti, V., Beecham, G. W., Wang, L., Dickson, D. W., Trojanowski, J. Q., Lee, V. M. Y., Mash, D. C., Frosch, M. P., Foroud, T. M., Honig, L. S., Montine, T. J., Dawson, T. M., Martin, E. R., Scott, W. K. & Vance, J. M., May 2014, In : Movement Disorders. 29, 6, p. 827-830 4 p.

Research output: Contribution to journalArticle

18 Scopus citations

A genome-wide association study of variants associated with acquisition of Staphylococcus aureus bacteremia in a healthcare setting

Nelson, C. L., Pelak, K., Podgoreanu, M. V., Ahn, S. H., Scott, W. K., Allen, A. S., Cowell, L. G., Rude, T. H., Zhang, Y., Tong, A., Ruffin, F., Sharma-Kuinkel, B. K. & Fowler, V. G., Feb 13 2014, In : BMC Infectious Diseases. 14, 1, 83.

Research output: Contribution to journalArticle

22 Scopus citations

Autophagy is redundant for the host defense against systemic Candida albicans infections

Smeekens, S. P., Malireddi, R. K., Plantinga, T. S., Buffen, K., Oosting, M., Joosten, L. A. B., Kullberg, B. J., Perfect, J. R., Scott, W. K., Van De Veerdonk, F. L., Xavier, R. J., Van De Vosse, E., Kanneganti, T. D., Johnson, M. D. & Netea, M. G., May 2014, In : European Journal of Clinical Microbiology and Infectious Diseases. 33, 5, p. 711-722 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

Cognitive and motor function in long-duration PARKIN-associated parkinson disease

Alcalay, R. N., Caccappolo, E., Mejia-Santana, H., Tang, M. X., Rosado, L., Reilly, M. O., Ruiz, D., Louis, E. D., Comella, C. L., Nance, M. A., Bressman, S. B., Scott, W. K., Tanner, C. M., Mickel, S. F., Waters, C. H., Fahn, S., Cote, L. J., Frucht, S. J., Ford, B., Rezak, M. & 16 others, Novak, K. E., Friedman, J. H., Pfeiffer, R. F., Marsh, L., Hiner, B., Payami, H., Molho, E., Factor, S. A., Nutt, J. G., Serrano, C., Arroyo, M., Ottman, R., Pauciulo, M. W., Nichols, W. C., Clark, L. N. & Marder, K. S., Jan 2014, In : JAMA Neurology. 71, 1, p. 62-67 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

Discovery and Functional Annotation of SIX6 Variants in Primary Open-Angle Glaucoma

Ulmer Carnes, M., Liu, Y. P., Allingham, R. R., Whigham, B. T., Havens, S., Garrett, M. E., Qiao, C., Katsanis, N., Wiggs, J. L., Pasquale, L. R., Ashley-Koch, A., Oh, E. C., Hauser, M. A., Brilliant, M., Budenz, D. L., Chin, H. R., Cooke Bailey, J., Fingert, J., Friedman, D. S., Gaasterland, D. & 22 others, Gaasterland, T., Haines, J., Kang, J. H., Lee, R. K., Lichter, P. R., Liu, Y., Loomis, S., McCarty, C. E., Moroi, S. E., Pericak-Vance, M., Realini, A., Richards, J. E., Schuman, J. S., Scott, W. K., Singh, K., Sit, A., Vollrath, D., Weinreb, R. N., Wollstein, G., Yaspan, B. L., Zack, D. & Zhang, K., May 1 2014, In : PLoS genetics. 10, 5, e1004372.

Research output: Contribution to journalArticle

48 Scopus citations

DNA copy number variants of known glaucoma genes in relation to primary open-angle glaucoma

Liu, Y., Garrett, M. E., Yaspan, B. L., Bailey, J. C., Loomis, S. J., Brilliant, M., Budenz, D. L., Christen, W. G., Fingert, J. H., Gaasterland, D., Gaasterland, T., Kang, J. H., Lee, R. K., Lichter, P., Moroi, S. E., Realini, A., Richards, J. E., Schuman, J. S., Scott, W. K., Singh, K. & 13 others, Sit, A. J., Vollrath, D., Weinreb, R., Wollstein, G., Zack, D. J., Zhang, K., Pericak-Vance, M. A., Haines, J. L., Pasquale, L. R., Wiggs, J. L., Allingham, R. R., Ashley-Koch, A. E. & Hauser, M. A., Nov 20 2014, In : Investigative Ophthalmology and Visual Science. 55, 12, p. 8251-8258 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Dusp3 and Psme3 Are Associated with Murine Susceptibility to Staphylococcus aureus Infection and Human Sepsis

Yan, Q., Sharma-Kuinkel, B. K., Deshmukh, H., Tsalik, E. L., Cyr, D. D., Lucas, J., Woods, C. W., Scott, W. K., Sempowski, G. D., Thaden, J., Rude, T. H., Ahn, S. H. & Fowler, V. G., Jun 2014, In : PLoS pathogens. 10, 6, e1004149.

Research output: Contribution to journalArticle

18 Scopus citations

Epiregulin (EREG) and human V-ATPase (TCIRG1): Genetic variation, ethnicity and pulmonary tuberculosis susceptibility in Guinea-Bissau and The Gambia

White, M. J., Tacconelli, A., Chen, J. S., Wejse, C., Hill, P. C., Gomes, V. F., Velez-Edwards, D. R., Østergaard, L. J., Hu, T., Moore, J. H., Novelli, G., Scott, W. K., Williams, S. M. & Sirugo, G., Sep 21 2014, In : Genes and Immunity. 15, 6, p. 370-377 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

NEIGHBORHOOD Consortium, BMES GWAS Group & Wellcome Trust Case Control Consortium 2, Jan 1 2014, In : Nature genetics. 46, 10, p. 1126-1130 5 p.

Research output: Contribution to journalArticle

113 Scopus citations

Glutamate Receptor Gene GRIN2A, Coffee, and Parkinson Disease

Hamza, T. H., Hill-Burns, E. M., Scott, W. K., Vance, J. M., Factor, S. A., Zabetian, C. P. & Payami, H., Nov 1 2014, In : PLoS genetics. 10, 11

Research output: Contribution to journalArticle

7 Scopus citations

Hypothesis-independent pathway analysis implicates GABA and Acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma

Bailey, J. N. C., Yaspan, B. L., Pasquale, L. R., Hauser, M. A., Kang, J. H., Loomis, S. J., Brilliant, M., Budenz, D. L., Christen, W. G., Fingert, J., Gaasterland, D., Gaasterland, T., Kraft, P., Lee, R. K., Lichter, P. R., Liu, Y., McCarty, C. A., Moroi, S. E., Richards, J. E., Realini, T. & 13 others, Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Vollrath, D., Wollstein, G., Zack, D. J., Zhang, K., Pericak-Vance, M. A., Allingham, R. R., Weinreb, R. N., Haines, J. L. & Wiggs, J. L., Jan 1 2014, In : Human genetics. 133, 10, p. 1319-1330 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

International Parkinson's Disease Genomics Consortium (IPDGC), Parkinson's Study Group (PSG) Parkinson's Research: The Organized GENetics Initiative (PROGENI), 23andMe, GenePD, NeuroGenetics Research Consortium (NGRC), Hussman Institute of Human Genomics (HIHG), The Ashkenazi Jewish Dataset Investigator, Cohorts for Health and Aging Research in Genetic Epidemiology (CHARGE), North American Brain Expression Consortium (NABEC), United Kingdom Brain Expression Consortium (UKBEC), Greek Parkinson's Disease Consortium & Alzheimer Genetic Analysis Group, Jan 1 2014, In : Nature genetics. 46, 9, p. 989-993 5 p.

Research output: Contribution to journalArticle

818 Scopus citations

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process

Blue Mountains Eye Study-GWAS groupw, NEIGHBORHOOD Consortiumz, Wellcome Trust Case Control Consortium 2 (WTCCC2), Data and Analysis Group, DNA, Genotyping, Data QC and Informatics Group & Publications Committee, 2014, In : Nature communications. 5, 4883.

Research output: Contribution to journalArticle

54 Scopus citations

Rare complement factor H variant associated with age-related macular degeneration in the Amish

Hoffman, J. D., Cooke Bailey, J. N., D'Aoust, L., Cade, W., Ayala-Haedo, J., Fuzzell, D., Laux, R., Adams, L. D., Reinhart-Mercer, L., Caywood, L., Whitehead-Gay, P., Agarwal, A., Wang, G., Scott, W. K., Pericak-Vance, M. A. & Haines, J. L., Jun 6 2014, In : Investigative Ophthalmology and Visual Science. 55, 7, p. 4455-4460 6 p.

Research output: Contribution to journalArticle

28 Scopus citations