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2019
2 Citations (Scopus)

Cyanobacterial neurotoxin BMAA and brain pathology in stranded dolphins

Davis, D. A., Mondo, K., Stern, E., Annor, A. K., Murch, S. J., Coyne, T. M., Brand, L. E., Niemeyer, M. E., Sharp, S., Bradley, W. G., Cox, P. A. & Mash, D. C., Mar 1 2019, In : PloS one. 14, 3, e0213346.

Research output: Contribution to journalArticle

Open Access
Dolphins
neurotoxins
Neurotoxins
Pathology
dolphins
2018
1 Citation (Scopus)

Estimation of environmental exposure: interpolation, kernel density estimation or snapshotting

Shi, X., Li, M., Hunter, O., Guetti, B., Andrew, A., Stommel, E., Bradley, W. G. & Karagas, M., Jan 1 2018, (Accepted/In press) In : Annals of GIS.

Research output: Contribution to journalArticle

interpolation
Interpolation
spatial analysis
Pollution
Health
2 Citations (Scopus)

Gene-Environment-Time Interactions in Neurodegenerative Diseases: Hypotheses and Research Approaches

Bradley, W. G., Andrew, A. S., Traynor, B. J., Chiò, A., Butt, T. H. & Stommel, E. W., Jan 1 2018, (Accepted/In press) In : Annals of Neurosciences. p. 261-267 7 p.

Research output: Contribution to journalArticle

Gene-Environment Interaction
Amyotrophic Lateral Sclerosis
Neurodegenerative Diseases
Research
Causality
9 Citations (Scopus)

Toenail mercury Levels are associated with amyotrophic lateral sclerosis risk

Andrew, A. S., Chen, C. Y., Caller, T. A., Tandan, R., Henegan, P. L., Jackson, B. P., Hall, B. P., Bradley, W. G. & Stommel, E. W., Jul 1 2018, In : Muscle and Nerve. 58, 1, p. 36-41 6 p.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Nails
Mercury
Fishes
Biomarkers
2017
10 Citations (Scopus)

Assessing Cyanobacterial Harmful Algal Blooms as Risk Factors for Amyotrophic Lateral Sclerosis

Torbick, N., Ziniti, B., Stommel, E., Linder, E., Andrew, A., Caller, T., Haney, J., Bradley, W. G., Henegan, P. L. & Shi, X., May 3 2017, (Accepted/In press) In : Neurotoxicity Research. p. 1-14 14 p.

Research output: Contribution to journalArticle

Harmful Algal Bloom
Phycocyanin
Amyotrophic Lateral Sclerosis
Lakes
Remote sensing
5 Citations (Scopus)

Cytokine expression levels in ALS: A potential link between inflammation and BMAA-triggered protein misfolding

Michaelson, N., Facciponte, D., Bradley, W. G. & Stommel, E., 2017, (Accepted/In press) In : Cytokine and Growth Factor Reviews.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Cytokines
Inflammation
Inflammasomes
Proteins
22 Citations (Scopus)

Environmental and Occupational Exposures and Amyotrophic Lateral Sclerosis in New England

Andrew, A. S., Caller, T. A., Tandan, R., Duell, E. J., Henegan, P. L., Field, N. C., Bradley, W. G. & Stommel, E. W., Feb 1 2017, In : Neurodegenerative Diseases. 17, 2-3, p. 110-116 7 p.

Research output: Contribution to journalArticle

New England
Environmental Exposure
Amyotrophic Lateral Sclerosis
Occupational Exposure
Hobbies

Erratum to: Assessing Cyanobacterial Harmful Algal Blooms as Risk Factors for Amyotrophic Lateral Sclerosis

Torbick, N., Ziniti, B., Stommel, E., Linder, E., Andrew, A., Caller, T., Haney, J., Bradley, W. G., Henegan, P. L. & Shi, X., Sep 5 2017, (Accepted/In press) In : Neurotoxicity Research. 1 p.

Research output: Contribution to journalArticle

Medical history of chemotherapy or immunosuppressive drug treatment and risk of amyotrophic lateral sclerosis (ALS)

Kuczmarski, T., Stommel, E. W., Riley, K., Tandan, R., Chaudhry, V., Clawson, L., Caller, T. A., Henegan, P. L., Facciponte, D. N., Bradley, W. G. & Andrew, A. S., Aug 1 2017, In : Journal of Neurology. 264, 8, p. 1763-1767 5 p.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Immunosuppressive Agents
Drug Therapy
Pharmaceutical Preparations
Therapeutics
359 Citations (Scopus)

Nusinersen versus sham control in infantile-onset spinal muscular atrophy

Finkel, R. S., Mercuri, E., Darras, B. T., Connolly, A. M., Kuntz, N. L., Kirschner, J., Chiriboga, C. A., Saito, K., Servais, L., Tizzano, E., Topaloglu, H., Tulinius, M., Montes, J., Glanzman, A. M., Bishop, K., Zhong, Z. J., Gheuens, S., Bennett, C. F., Schneider, E., Farwell, W. & 378 others, De Vivo, D. C., Bradley, W. G., Schroth, M. K., Bodensteriner, J. B., Davis, C. S., Shell, R., Hen, J., Austin, E. D., Aziz-Zaman, S., Cappell, J., Constantinescu, A., Cruz, R., Dastgir, J., Dunaway, S., Engelstad, K., Gormley, M., Holuba La Marca, N., Khandji, A., Kramer, S., Marra, J., Ortiz-Miller, C., Popolizio, M., Salazar, R., Sanabria, L., Weimer, L., Anand, P., Gadeken, R., Golumbek, P. T., Siener, C., Zaidman, C. M., Al-Ghamdi, F., Berde, C., Ghosh, P., Graham, R., Harrington, T., Koka, A., Laine, R., Liew, W., Mirek, E., Ordonez, G., Pasternak, A., Quigley, J., Sethna, N., Souris, M., Szelag, H., Wand, L., Day, J. W., D'Souza, G., Duong, T. T., Gee, R., Kitsuwa-Lowe, J., McFall, D., Patnaik, S., Paulose, S., Perez, J., Proud, C., Purse, B., Ramamurthi, R. J., Sakamuri, S., Sampson, J., Sanjanwala, B., Tesi Rocha, A. C., Watson, K., Welsh, L., Pena, L. D. M., Case, L., Coates, J., DeArmey, S., Homi, M. M., Milleson, C., Nelson, N., Ross, A., Smith, E., Taicher, B., Wootton, J., Finanger, E., Benjamin, D., Frank, A., Roberts, C., Russman, B., Zilke, K., Berry, D., Civitello, M., Cook, D., Endsley, J. D., Johnson, C., Kasper, M., Leon, W., Lim, A., O'Reardon, K., Sigurdardottir, L. Y., Turner, J., Weber-Guzman, F., Zinn, M., Iannaccone, S. T., Castro, D., Cowie, M., Farrow-Gillespie, A., Herbert, A., Kauk, M., McElroy, D., Miller, N., Nelson, L., Smith, L., Spain, T., Trest, S., Johnson, N., Butterfield, R., DiBella, D., Mayne, K., Newcomb, T. M., Rausch, N., Blomgren, C., Choi, H. W., Epstein, L., Goldman, S., Krosschell, K., Krueger, J., Kurz, J., Rao, V., Parsons, J., Allen, V., Bielsky, A., Booker, K., Camuto, A., Carry, T., Fuhr, P., Gibbons, M., Janas, J., Johnson, H., Kelly, C., Lord-Halvorson, L. S., Nicolarsen, S., Shea, S., Tran, V., VanderVeen, G., Yang, M., Zimmerman, C., Shieh, P., Parziale, N., Rao, L., Said, J. W., Shu, F., Skura, C., Staudt, L., Tennekoon, G., Adang, L., Brandsema, J., Chadehumbe, M., Flickinger, J., Kichula, E., Stanford, D., Toms, M., Zigmont, J., Oskoui, M., Arpin, S., Dinunzio, P., Ingelmo, P. M., Poulin, C., Rivera, G., Sabapathy, C., Srour, M., Turgeon-Desilet, S., Zielinski, D., Selby, K., King, C., Lee, J., Michoulas, A., Roland, E., Vajsar, J., Chau, V., Dowling, J., Haldenby, R., Miki, M., So, S., Pascual Pascual, S. I., Martinez Bermejo, A., Epinosa Garcia, S., Garcia Guixot, S., Martinez Moreno, M. M., del Pilar Tirado Requero, M., del Mar Garcia Romero, M., Aguilar, C., Munell Casadesus, F., Gomez Garcia de la Banda, M. B., Gallardo, M., Gili, G., Alavarez Molinero, M., de Los Angeles Tormos Munoz, M., Palacios, N. J., Planas Pascual, B., del Mar Melendez Plumed, M., Rucian, A. F., Toro Tamargo, E., Gratacos Vinola, M., Borell, S., Eckenweiler, M., Krüger, M., Pechmann, A., Rippberger, B., Stein, S., Vogt, S., Wider, S., Schara, U., Andres, B., Della Marina, A., Ganfuss, A., Jachertz, P., Koelbel, H., Rupprich, K., Schroers, E. S., Sponemann, N., Bruno, C., Fiorillo, C., Garaventa, A., Lanteri, P., Lanzillotta, V., Manzitti, C., Pedermonte, M., Tacchetti, P., Trucco, F., Zuffi, A., De Sanctis, R., Fanelli, L., Luigetti, M., Palermo, C., Pane, M., Piastra, M., Sivo, S., Gargaun, E., Gidaro, T., Gilabert, S., Léger, P. L., Le Moing, A. G., Lilien, C., Mayer, M., Ollievier, Q., Rambaud, J., Taytard, J., Vialle, R., Voit, T., Muntoni, F., D'Argenzio, L., Lister, PH., Manzur, A., Pisco Domingos, J., Ramsey, D., Ricotti, V., Schottlaender, L., Scoto, M., Scuplak, S. M., Selby, V., Straub, V., Baily, S., Bertoli, M., Mayhew, A. G., Lofra, R. M., Murphy, A., Wood, C., Darin, N., Eldblom, J., Kimber, E., Kroksmark, A. K., Lindstedt, A., Michael, E., Sofou, K., Deconinck, N., Christiaens, A., Coppens, S., DeCock, K., De Vos voor, E., Dorban, F., Gilbert, G., Rooze, S., Tahon, V., Van Coster, R., Van Der Looven, R., Vanlander, A., Vens, D., Verhelst, H., Wenderickx, B., Wittevrongel, S., Farrar, M., Berthon-Jones, N., Doumit, M. A., Herbert, K. J., Kandula, T., Morrison, M., O'Brien, J., Richardson, S., Ferreira Sampaio, H. A., Teoh, H. L., Ryan, M., Carroll, K. M., De Valle, K. L., Villano, D., Woodcock, I., Yiu, E. M., Ardicli, D., Gunbey, C., Haliloglu, V. G., Karaduman, A. A., Konuskan, B., Yildiz Sarikaya, F. G., Serdaroglu, E., Tanyildiz, M., Temucin, C. M., Yildirim, M., Yilmaz, O. T., Arakawa, R., Chiba, Y., Eto, K., Hirasawa, K., Ikai, T., Ito, S., Ito, Y., Kaburagi, Y., Kaneko, H., Matsumaru, S., Matsushima, N., Mizuochi, K., Nagata, S., Nakatsukasa, H., Nishikawa, A., Otani, Y., Sato, T., Shichiji, M., Sugimoto, K., Takeshita, A., Yanagishita, T., Yamauchi, A., Takeshima, Y., Fujino, T., Fukuda, N., Lee, T., Oriyama, K., Shibano, T., Shimomura, H., Tachikawa, T., Tanaka, Y., Taniguchi, N., Chae, J. H., Choi, S. A., Chun, S. M., Jo, H., Kim, H., Kim, S. Y., Lee, J. S., Lim, B. C., Shin, H. I., Son, W. S., Chan, S., Chung, A. C., Yan, C. S., Stella, C., Joseph, C. K. W., Ng, C. S., Alvin, H. C. C., Janice, I. J. K., Wendy, L. W. M., Chui-San, M. N., Ki, N. Y., Shun, T. N., Connie, W. Y., Virginia, W. C., Yvonne, Y., Jong, Y. J., Chen, T. H., Chou, P. C., Chou, Y. H., Chung, H. W., Hsu, J. H., Ju, Y. H., Liang, W. C., Shih, H. H., Wang, H. Y., Wu, Y. C. & Zeng, Y. S., Nov 2 2017, In : New England Journal of Medicine. 377, 18, p. 1723-1732 10 p.

Research output: Contribution to journalArticle

Spinal Muscular Atrophies of Childhood
Spinal Muscular Atrophy
Control Groups
Disease-Free Survival
Motor Neurons
3 Citations (Scopus)

Studies of Environmental Risk Factors in Amyotrophic Lateral Sclerosis (ALS) and a Phase I Clinical Trial of l-Serine

Bradley, W. G., Miller, R. X., Levine, T. D., Stommel, E. W. & Cox, P. A., May 19 2017, (Accepted/In press) In : Neurotoxicity Research. p. 1-7 7 p.

Research output: Contribution to journalArticle

Clinical Trials, Phase I
Amyotrophic Lateral Sclerosis
Serine
Environmental Pollutants
New England
2016
10 Citations (Scopus)

Phase I clinical trial of safety of L-serine for ALS patients

Levine, T. D., Miller, R. G., Bradley, W. G., Moore, D. H., Saperstein, D. S., Flynn, L. E., Katz, J. S., Forshew, D. A., Metcalf, J. S., Banack, S. A. & Cox, P. A., Aug 25 2016, (Accepted/In press) In : Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. p. 1-5 5 p.

Research output: Contribution to journalArticle

Clinical Trials, Phase I
Serine
Safety
Vital Capacity
Disease Progression
2015
1 Citation (Scopus)

Spatial cluster analysis of population amyotrophic lateral sclerosis risk in Ireland

Bradley, W. G., Stommel, E. W., Shi, X., Torbick, N. M., Caller, T. A. & Sabel, C. E., Nov 17 2015, In : Neurology. 85, 20, p. 1822-1823 2 p.

Research output: Contribution to journalArticle

Spatial Analysis
Amyotrophic Lateral Sclerosis
Ireland
Cluster Analysis
Registries
3 Citations (Scopus)
Motor Neuron Disease
Muscular Dystrophies
Research
2014
40 Citations (Scopus)

Detection of cyanobacterial neurotoxin β-N-methylamino-l-alanine within shellfish in the diet of an ALS patient in Florida

Banack, S. A., Metcalf, J. S., Bradley, W. G. & Cox, P. A., Jan 1 2014, In : Toxicon. 90, p. 167-173 7 p.

Research output: Contribution to journalArticle

Neurodegenerative diseases
Shellfish
Neurotoxins
Nutrition
Alanine

Theodore L. Munsat, MD (1930-2013.

Bradley, W. G. & Rowland, L. P., 2014, In : Neurology. 82, 14, p. 1202-1203 2 p.

Research output: Contribution to journalArticle

Teaching
Neurology
2013
23 Citations (Scopus)

Current pathways for epidemiological research in amyotrophic lateral sclerosis

Factor-Litvak, P., Al-Chalabi, A., Ascherio, A., Bradley, W. G., Chío, A., Garruto, R., Hardiman, O., Kamel, F., Kasarskis, E., McKee, A., Nakano, I., Nelson, L. M. & Eisen, A., May 1 2013, In : Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 14, SUPPL1, p. 33-43 11 p.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Research
Registries
Epidemiology
Hydroxymethylglutaryl-CoA Reductase Inhibitors
55 Citations (Scopus)

Is exposure to cyanobacteria an environmental risk factor for amyotrophic lateral sclerosis and other neurodegenerative diseases?

Bradley, W. G., Borenstein, A. R., Nelson, L. M., Codd, G. A., Rosen, B. H., Stommel, E. W. & Cox, P. A., Sep 1 2013, In : Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 14, 5-6, p. 325-333 9 p.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Cyanobacteria
Neurodegenerative Diseases
Gene-Environment Interaction
Environmental Exposure
2012
34 Citations (Scopus)

Pseudobulbar affect: Burden of illness in the USA

Colamonico, J., Formella, A. & Bradley, W. G., Sep 1 2012, In : Advances in Therapy. 29, 9, p. 775-798 24 p.

Research output: Contribution to journalArticle

Cost of Illness
Quality of Life
Health Status
Crying
Visual Analog Scale
2011
55 Citations (Scopus)

Pseudobulbar affect: An under-recognized and under-treated neurological disorder

Work, S. S., Colamonico, J. A., Bradley, W. G. & Kaye, R. E., Jul 1 2011, In : Advances in Therapy. 28, 7, p. 586-601 16 p.

Research output: Contribution to journalArticle

Nervous System Diseases
Crying
Nervous System
Government Agencies
Amyotrophic Lateral Sclerosis
1 Citation (Scopus)

Washed cycad flour contains β-n-methyl amino-L-alanine and may explain parkinsonism symptoms

Banack, S. A., Nunn, P. B., Cheng, R. & Bradley, W. G., Feb 1 2011, In : Annals of Neurology. 69, 2

Research output: Contribution to journalArticle

Cycas
Diamino Amino Acids
Plant Extracts
Neurotoxins
Parkinsonian Disorders