Find Research Outputs

Search in all content

Filters for Research Output

Search concepts
Selected Filters

Publication Year

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011

Author

  • Savita G Pahwa
2020

A delayed fractionated dose RTS,S AS01 vaccine regimen mediates protection via improved T follicular helper and B cell responses

Pallikkuth, S., Chaudhury, S., Lu, P., Pan, L., Jongert, E., Wille-Reece, U. & Pahwa, S., Apr 2020, In : eLife. 9

Research output: Contribution to journalArticle

Open Access

A therapeutic HIV-1 vaccine reduces markers of systemic immune activation and latent infection in patients under highly active antiretroviral therapy

Pallikkuth, S., Bolivar, H., Fletcher, M. A., Babic, D. Z., De Armas, L. R., Gupta, S., Termini, J. M., Arheart, K. L., Stevenson, M., Tung, F. Y., Fischl, M. A., Pahwa, S. & Stone, G. W., Jun 2 2020, In : Vaccine. 38, 27, p. 4336-4345 10 p.

Research output: Contribution to journalArticle

COVID19: A Systematic Approach to Early Identification and Healthcare Worker Protection

Zhao, Y., Cui, C., Zhang, K., Liu, J., Xu, J., Nisenbaum, E., Huang, Y., Qin, G., Chen, B., Hoffer, M., Blanton, S. H., Telischi, F., Hare, J. M., Daunert, S., Shukla, B., Pahwa, S. G., Jayaweera, D. T., Farmer, P. E., del Rio, C., Liu, X. & 1 others, Shu, Y., May 19 2020, In : Frontiers in Public Health. 8, 205.

Research output: Contribution to journalReview article

Open Access

Double Jeopardy: Methamphetamine Use and HIV as Risk Factors for COVID-19

Carrico, A. W., Horvath, K. J., Grov, C., Moskowitz, J. T., Pahwa, S., Pallikkuth, S. & Hirshfield, S., Jan 1 2020, (Accepted/In press) In : AIDS and Behavior.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
Open Access
2 Scopus citations

Getting to the point: Methamphetamine injection is associated with biomarkers relevant to HIV pathogenesis

Miller, M., Lee, J. Y., Fulcher, J. A., Roach, M. E., Dilworth, S. E., Chahine, A., Pallikkuth, S., Fuchs, D., Pahwa, S. & Carrico, A. W., Aug 1 2020, In : Drug and Alcohol Dependence. 213, 108133.

Research output: Contribution to journalArticle

Higher PIK3C2B gene expression of H1N1+ specific B-cells is associated with lower H1N1 immunogenicity after trivalent influenza vaccination in HIV infected children

Cotugno, N., Zicari, S., Morrocchi, E., de Armas, L. R., Pallikkuth, S., Rinaldi, S., Ruggiero, A., Manno, E. C., Zangari, P., Chiriaco, M., Bernardi, S., Andrews, S. F., Cagigi, A., Rossi, P., McDermott, A. B., Pahwa, S. & Palma, P., Jun 2020, In : Clinical Immunology. 215, 108440.

Research output: Contribution to journalArticle

HIV and carotid atherosclerosis: a mediational model

Alcaide, M. L., Rodriguez, V. J., Abbamonte, J. M., Pallikuth, S., Langlie, J., Soni, M., Weiss, S. M., Hurwitz, B. E., Pahwa, S., Jones, D. L. & Kumar, M., Jul 2 2020, In : AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV. 32, 7, p. 907-911 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Impact of early antiretroviral therapy initiation on HIV-specific CD4 and CD8 T cell function in perinatally infected children

Rinaldi, S., Pallikkuth, S., Cameron, M., De Armas, L. R., Cotugno, N., Dinh, V., Pahwa, R., Richardson, B., Saini, S. R., Rocca, S., Lain, M. G., Williams, S. L., Palma, P. & Pahwa, S., Feb 1 2020, In : Journal of Immunology. 204, 3, p. 540-549 10 p.

Research output: Contribution to journalArticle

2019

A prospective study of the immune reconstitution inflammatory syndrome (IRIS) in HIV-infected children from high prevalence countries

on behalf of the P1073 team, 2019, In : PloS one. 14, 7, e0211155.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Compromised steady-state germinal center activity with age in nonhuman primates

Shankwitz, K., Pallikkuth, S., Sirupangi, T., Kirk Kvistad, D., Russel, K. B., Pahwa, R., Gama, L., Koup, R. A., Pan, L., Villinger, F., Pahwa, S. & Petrovas, C., Jan 1 2019, (Accepted/In press) In : Aging Cell. e13087.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Current challenges and solutions in research and clinical care of older persons living with HIV: Findings presented at the 9th international workshop on HIV and aging

Sundermann, E. E., Erlandson, K. M., Pope, C. N., Rubtsova, A., Montoya, J., Moore, A. A., Marzolini, C., O'Brien, K. K., Pahwa, S., Payne, B. A. I., Rubin, L. H., Walmsley, S., Haughey, N. J., Montano, M., Karris, M. Y., Margolick, J. B. & Moore, D. J., Nov 1 2019, In : AIDS research and human retroviruses. 35, 11-12, p. 985-998 14 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Dysfunctional peripheral T follicular helper cells dominate in people with impaired influenza vaccine responses: Results from the FLORAH study

Pallikkuth, S., De Armas, L. R., Rinaldi, S., George, V. K., Pan, L., Arheart, K. L., Pahwa, R. & Pahwa, S., May 2019, In : PLoS biology. 17, 5, e3000257.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Harvard HIV and aging workshop: Perspectives and Priorities from Claude D. Pepper Centers and Centers for AIDS Research

Montano, M., Bhasin, S., D'Aquila, R. T., Erlandson, K. M., Evans, W. J., Funderburg, N. T., Justice, A., Ndhlovu, L. C., Ojikutu, B., Pahor, M., Pahwa, S., Ryan, A. S., Schrack, J., Schultz, M. B., Sebastiani, P., Sinclair, D. A., Tripp, J., Walker, B., Womack, J. A., Yung, R. & 1 others, Reeves, R. K., Nov 1 2019, In : AIDS research and human retroviruses. 35, 11-12, p. 999-1012 14 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells

Hyun, J., McMahon, R. S., Lang, A. L., Edwards, J. S., Badilla, A. D., Greene, M. E., Stone, G. W., Pallikkuth, S., Stevenson, M., Dykxhoorn, D. M., Kottilil, S., Pahwa, S. & Thomas, E., Jul 2019, In : PLoS pathogens. 15, 7, e1007883.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Human Immunodeficiency Virus (HIV)-Antibody repertoire estimates reservoir size and time of antiretroviral therapy initiation in virally suppressed perinatally HIV-infected children

Rocca, S., Zangari, P., Cotugno, N., De Rossi, A., Ferns, B., Petricone, D., Rinaldi, S., Giaquinto, C., Bernardi, S., Rojo, P., Rossi, P., Pahwa, S., Nastouli, E. & Palma, P., Mar 20 2019, In : Journal of the Pediatric Infectious Diseases Society. 8, 5, p. 433-438 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Implications of immune checkpoint expression during aging in HIV-infected people on antiretroviral therapy

De Armas, L. R., Pallikkuth, S., Rinaldi, S., Pahwa, R. & Pahwa, S., Nov 1 2019, In : AIDS research and human retroviruses. 35, 11-12, p. 1112-1122 11 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Psychosocial Correlates of Monocyte Activation and HIV Persistence in Methamphetamine Users

Grosgebauer, K., Salinas, J., Sharkey, M., Roach, M., Pallikkuth, S., Dilworth, S. E., Pahwa, S., Koru-Sengul, T., Stevenson, M. & Carrico, A. W., Mar 15 2019, In : Journal of Neuroimmune Pharmacology. 14, 1, p. 16-22 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Searching for the origin of the enigmatic circulating T follicular helper cells

Pahwa, S., Aug 1 2019, In : Journal of Clinical Investigation. 129, 8, p. 3048-3051 4 p.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Single Cell Profiling Reveals PTEN Overexpression in Influenza-Specific B cells in Aging HIV-infected individuals on Anti-retroviral Therapy

de Armas, L. R., Pallikkuth, S., Pan, L., Rinaldi, S., Cotugno, N., Andrews, S., Pahwa, R., McDermott, A. B., Palma, P. & Pahwa, S., Dec 1 2019, In : Scientific reports. 9, 1, 2482.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2018

Altered immune cell follicular dynamics in HIV infection following influenza vaccination

Moysi, E., Pallikkuth, S., De Armas, L. R., Gonzalez, L. E., Ambrozak, D., George, V., Huddleston, D., Pahwa, R., Koup, R. A., Petrovas, C. & Pahwa, S. G., Jul 2 2018, In : Journal of Clinical Investigation. 128, 7, p. 3171-3185 15 p.

Research output: Contribution to journalArticle

17 Scopus citations

Cardiac morbidity in HIV infection is associated with checkpoint inhibitor LAG-3 on CD4 T cells

Pallikkuth, S., Pahwa, R., Kausalya, B., Saravanan, S., Pan, L., Vignesh, R., Iqbal, S., Solomon, S. S., Murugavel, K. G., Poongulali, S., Kumarasamy, N. & Pahwa, S., Oct 2018, In : PloS one. 13, 10, e0206256.

Research output: Contribution to journalArticle

3 Scopus citations

Circulating inflammatory monocytes contribute to impaired influenza vaccine responses in HIV-infected participants

George, V. K., Pallikkuth, S., Pahwa, R., De Armas, L. R., Rinaldi, S., Pan, L. & Pahwa, S. G., Jun 19 2018, In : AIDS. 32, 10, p. 1219-1228 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Effect of antiretroviral therapy on allele-associated Lp(a) level in women with HIV in the Women's Interagency HIV Study

Enkhmaa, B., Anuurad, E., Zhang, W., Li, C. S., Kaplan, R., Lazar, J., Merenstein, D., Karim, R., Aouizerat, B., Cohen, M., Butler, K., Pahwa, S., Ofotokun, I., Adimora, A. A., Golub, E. & Berglund, L., Jan 1 2018, In : Journal of Lipid Research. 59, 10, p. 1967-1976 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Impact of aging and HIV infection on serologic response to seasonal influenza vaccination

Pallikkuth, S., De Armas, L. R., Pahwa, R., Rinaldi, S., George, V. K., Sanchez, C. M., Pan, L., Dickinson, G., Rodriguez, A. E., Fischl, M. A., Alcaide, M. L. & Pahwa, S. G., Jun 1 2018, In : AIDS. 32, 9, p. 1085-1094 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Microbial Translocation and Immune Activation in HIV-1 Infected Pregnant Women

Mitchell, C. D., Dominguez, S., Roach, M., George, V., Rinaldi, S., Fischl, M. A., Potter, J. E., Tyson, B. & Pahwa, S. G., Jan 1 2018, In : Current HIV Research. 16, 3, p. 208-215 8 p.

Research output: Contribution to journalArticle

Recent stimulant use and leukocyte gene expression in methamphetamine users with treated HIV infection

Carrico, A., Flentje, A., Kober, K., Lee, S., Hunt, P., Riley, E. D., Shoptaw, S., Flowers, E., Dilworth, S. E., Pahwa, S. G. & Aouizerat, B. E., Jan 1 2018, (Accepted/In press) In : Brain, Behavior, and Immunity.

Research output: Contribution to journalArticle

9 Scopus citations

Substance-associated elevations in monocyte activation among methamphetamine users with treated HIV infection

Carrico, A. W., Cherenack, E. M., Roach, M. E., Riley, E. D., Oni, O., DIlworth, S. E., Shoptaw, S., Hunt, P., Roy, S., Pallikkuth, S. & Pahwa, S., Mar 27 2018, In : AIDS. 32, 6, p. 767-771 5 p.

Research output: Contribution to journalArticle

10 Scopus citations
2017

Associations of Plasma Cytokine and Microbial Translocation Biomarkers With Immune Reconstitution Inflammatory Syndrome

AIDS Clinical Trials Group A5202 Study Team, Nov 27 2017, In : The Journal of infectious diseases. 216, 9, p. 1159-1163 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Concomitant nevirapine impacts pharmacokinetic exposure to the antimalarial artemether-lumefantrine in African children

IMPAACT P1079 protocol team, Oct 2017, In : PloS one. 12, 10, e0186589.

Research output: Contribution to journalArticle

4 Scopus citations
14 Scopus citations

Immune development in HIV-exposed uninfected children born to HIV-infected women

Miyamoto, M., Gouvêa, A. F. T. B., Ono, E., Succi, R. C. M., Pahwa, S. & de Moraes-Pinto, M. I., Feb 28 2017, In : Revista do Instituto de Medicina Tropical de Sao Paulo. 59, e30.

Research output: Contribution to journalArticle

6 Scopus citations

Induction of il21 in peripheral t follicular helper cells is an indicator of influenza vaccine response in a previously vaccinated HIV-infected pediatric cohort

De Armas, L. R., Cotugno, N., Pallikkuth, S., Pan, L., Rinaldi, S., Sanchez, M. C., Gonzalez, L., Cagigi, A., Rossi, P., Palma, P. & Pahwa, S., Mar 1 2017, In : Journal of Immunology. 198, 5, p. 1995-2005 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Lipoprotein(a) and HIV: Allele-specific apolipoprotein(a) levels predict carotid intima-media thickness in hiv-infected young women in the women's interagency HIV study

Enkhmaa, B., Anuurad, E., Zhang, W., Li, C. S., Kaplan, R., Lazar, J., Merenstein, D., Karim, R., Aouizerat, B., Cohen, M., Butler, K., Pahwa, S., Ofotokun, I., Adimora, A. A., Golub, E. & Berglund, L., May 1 2017, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 37, 5, p. 997-1004 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Paradoxical aging in HIV: Immune senescence of B Cells is most prominent in young age

Rinaldi, S., Pallikkuth, S., George, V. K., de Armas, L. R., Pahwa, R., Sanchez, C. M., Pallin, M. F., Pan, L., Cotugno, N., Dickinson, G., Rodriguez, A., Fischl, M., Alcaide, M., Gonzalez, L., Palma, P. & Pahwa, S., 2017, In : Aging. 9, 4, p. 1307-1325 19 p.

Research output: Contribution to journalArticle

13 Scopus citations

Perturbation of B cell gene expression persists in HIV-infected children despite effective antiretroviral therapy and predicts H1N1 response

Cotugno, N., De Armas, L., Pallikkuth, S., Rinaldi, S., Issac, B., Cagigi, A., Rossi, P., Palma, P. & Pahwa, S., Sep 11 2017, In : Frontiers in immunology. 8, SEP, 1083.

Research output: Contribution to journalArticle

10 Scopus citations

T follicular helper cells and B cell dysfunction in aging and HIV-1 infection

Pallikkuth, S., de Armas, L., Rinaldi, S. & Pahwa, S., Oct 23 2017, In : Frontiers in immunology. 8, OCT, 1380.

Research output: Contribution to journalShort survey

19 Scopus citations
2016

A survey of tuberculosis infection control practices at the NIH/NIAID/DAIDS-supported clinical trial sites in low and middle income countries

HIV Network Coordinating (HANC) TB Diagnostic Laboratory Working Division of AIDS, National Institute of Allergy and Infectious Diseases, Jun 10 2016, In : BMC Infectious Diseases. 16, 1, 269.

Research output: Contribution to journalArticle

5 Scopus citations

A therapeutic HIV-1 vaccine enhances anti-HIV-1 immune responses in patients under highly active antiretroviral therapy

Tung, F. Y., Tung, J. K., Pallikkuth, S., Pahwa, S. G. & Fischl, M. A., Apr 27 2016, In : Vaccine. 34, 19, p. 2225-2232 8 p.

Research output: Contribution to journalArticle

10 Scopus citations
67 Scopus citations
2015

Early antiretroviral therapy in children perinatally infected with HIV: A unique opportunity to implement immunotherapeutic approaches to prolong viral remission

Klein, N., Palma, P., Luzuriaga, K., Pahwa, S., Nastouli, E., Gibb, D. M., Rojo, P., Borkowsky, W., Bernardi, S., Zangari, P., Calvez, V., Compagnucci, A., Wahren, B., Foster, C., Munoz-Fernández, M. Á., De Rossi, A., Ananworanich, J., Pillay, D., Giaquinto, C. & Rossi, P., Sep 1 2015, In : The Lancet Infectious Diseases. 15, 9, p. 1108-1114 7 p.

Research output: Contribution to journalReview article

26 Scopus citations

Effect of cytomegalovirus co-infection on normalization of selected T-cell subsets in children with perinatally acquired HIV infection treated with combination antiretroviral therapy

Pediatric AIDS Clinical Trials Group Protocol 366, Mar 20 2015, In : PloS one. 10, 3, e0120474.

Research output: Contribution to journalArticle

2 Scopus citations

HIV infection worsens age-associated defects in antibody responses to influenza vaccine

George, V. K., Pallikkuth, S., Parmigiani, A., Alcaide, M., Fischl, M., Arheart, K. L. & Pahwa, S., Jun 15 2015, In : Journal of Infectious Diseases. 211, 12, p. 1959-1968 10 p.

Research output: Contribution to journalArticle

29 Scopus citations
2014

CD4 Depletion in SIV-Infected Macaques Results in Macrophage and Microglia Infection with Rapid Turnover of Infected Cells

Micci, L., Alvarez, X., Iriele, R. I., Ortiz, A. M., Ryan, E. S., McGary, C. S., Deleage, C., McAtee, B. B., He, T., Apetrei, C., Easley, K., Pahwa, S., Collman, R. G., Derdeyn, C. A., Davenport, M. P., Estes, J. D., Silvestri, G., Lackner, A. A. & Paiardini, M., Oct 1 2014, In : PLoS pathogens. 10, 10

Research output: Contribution to journalArticle

54 Scopus citations

Immune activation is associated with increased gut microbial translocation in treatment-naive, HIV-infected children in a resource-limited setting

Pilakka-Kanthikeel, S., Kris, A., Selvaraj, A., Swaminathan, S. & Pahwa, S., May 1 2014, In : Journal of Acquired Immune Deficiency Syndromes. 66, 1, p. 16-24 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Premature B-cell senescence as a consequence of chronic immune activation: Implications for vaccination of immune compromised individuals

Palma, P., Rinaldi, S., Cotugno, N., Santilli, V., Pahwa, S., Rossi, P. & Cagigi, A., Jul 1 2014, In : Human Vaccines and Immunotherapeutics. 10, 7, p. 2083-2088 6 p.

Research output: Contribution to journalReview article

11 Scopus citations

Premature immune senescence during HIV-1 vertical infection relates with response to influenza vaccination

Cagigi, A., Rinaldi, S., Di Martino, A., Manno, E. C., Zangari, P., Aquilani, A., Cotugno, N., Nicolosi, L., Villani, A., Bernardi, S., Donatelli, I., Pahwa, S., Rossi, P. & Palma, P., Feb 2014, In : Journal of Allergy and Clinical Immunology. 133, 2, p. 592-594.e1

Research output: Contribution to journalArticle

22 Scopus citations
2013
18 Scopus citations