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  • Andrew V Schally
2020

Acute promyelocytic leukemia (APL): A review of the literature

Jimenez, J. J., Chale, R. S., Abad, A. C. & Schally, A. V., Mar 17 2020, In : Oncotarget. 11, 11, p. 992-1003 12 p.

Research output: Contribution to journalReview article

Open Access

Anti-inflammatory effects of α-MSH through p-CREB expression in sarcoidosis like granuloma model

Zhang, C., Chery, S., Lazerson, A., Altman, N. H., Jackson, R., Holt, G., Campos, M., Schally, A. V. & Mirsaeidi, M., Dec 1 2020, In : Scientific reports. 10, 1, 7277.

Research output: Contribution to journalArticle

Open Access

Antinflammatory, antioxidant, and behavioral effects induced by administration of growth hormone-releasing hormone analogs in mice

Recinella, L., Chiavaroli, A., Orlando, G., Ferrante, C., Marconi, G. D., Gesmundo, I., Granata, R., Cai, R., Sha, W., Schally, A. V., Brunetti, L. & Leone, S., Dec 1 2020, In : Scientific reports. 10, 1, 732.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Extracorporeal apheresis therapy for Alzheimer disease—targeting lipids, stress, and inflammation

Bornstein, S. R., Voit-Bak, K., Rosenthal, P., Tselmin, S., Julius, U., Schatz, U., Boehm, B. O., Thuret, S., Kempermann, G., Reichmann, H., Chrousos, G. P., Licinio, J., Wong, M. L., Schally, A. V. & Straube, R., Feb 1 2020, In : Molecular psychiatry. 25, 2, p. 275-282 8 p.

Research output: Contribution to journalReview article

2 Scopus citations

GHRH Antagonists Protect against Hydrogen Peroxide-Induced Breakdown of Brain Microvascular Endothelium Integrity

Barabutis, N., Akhter, M. S., Uddin, M. A., Kubra, K. T. & Schally, A. V., May 1 2020, In : Hormone and Metabolic Research. 52, 5, p. 336-339 4 p.

Research output: Contribution to journalArticle

Publisher Correction: Antinflammatory, antioxidant, and behavioral effects induced by administration of growth hormone-releasing hormone analogs in mice (Scientific Reports, (2020), 10, 1, (732), 10.1038/s41598-019-57292-z)

Recinella, L., Chiavaroli, A., Orlando, G., Ferrante, C., Marconi, G. D., Gesmundo, I., Granata, R., Cai, R., Sha, W., Schally, A. V., Brunetti, L. & Leone, S., Dec 1 2020, In : Scientific reports. 10, 1, 4850.

Research output: Contribution to journalComment/debate

Open Access

Signaling mechanisms of growth hormone-releasing hormone receptor in LPS-induced acute ocular inflammation

Liang, W. C., Ren, J. L., Yu, Q. X., Li, J., Ng, T. K., Chu, W. K., Qin, Y. J., Chu, K. O., Schally, A. V., Pang, C. P. & Chan, S. O., Mar 17 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 11, p. 6067-6074 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Splice variant of growth hormone-releasing hormone receptor drives esophageal squamous cell carcinoma conferring a therapeutic target

Xiong, X., Ke, X., Wang, L., Yao, Z., Guo, Y., Zhang, X., Chen, Y., Pang, C. P., Schally, A. V. & Zhang, H., Mar 24 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 12, p. 6726-6732 7 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Stimulation of neuroendocrine differentiation in prostate cancer cells by GHRH and its blockade by GHRH antagonists

Muñoz-Moreno, L., Carmena, M. J., Schally, A. V., Prieto, J. C. & Bajo, A. M., Jun 1 2020, In : Investigational New Drugs. 38, 3, p. 746-754 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

The role of FSH and LH in prostate cancer and cardiometabolic comorbidities

Crawford, E. D. & Schally, A. V., Apr 1 2020, In : The Canadian journal of urology. 27, 2, p. 10167-10173 7 p.

Research output: Contribution to journalArticle

The targeted LHRH analog AEZS-108 alters expression of genes related to angiogenesis and development of metastasis in uveal melanoma

Fodor, K., Dobos, N., Schally, A., Steiber, Z., Olah, G., Sipos, E., Szekvolgyi, L. & Halmos, G., Jan 14 2020, In : Oncotarget. 11, 2, p. 175-187 13 p.

Research output: Contribution to journalArticle

Open Access
2019

Actions and Potential Therapeutic Applications of Growth Hormone-Releasing Hormone Agonists

Schally, A. V., Zhang, X., Cai, R., Hare, J. M., Granata, R. & Bartoli, M., Jan 1 2019, In : Endocrinology. 160, 7, p. 1600-1612 13 p.

Research output: Contribution to journalReview article

Open Access
7 Scopus citations

Antagonists of growth hormone-releasing hormone (GHRH) inhibit the growth of human malignant pleural mesothelioma

Villanova, T., Gesmundo, I., Audrito, V., Vitale, N., Silvagno, F., Musuraca, C., Righi, L., Libener, R., Riganti, C., Bironzo, P., Deaglio, S., Papotti, M., Cai, R., Sha, W., Ghigo, E., Schally, A. V. & Granata, R., Feb 5 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 6, p. 2226-2231 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Exquisite sensitivity of adrenocortical carcinomas to induction of ferroptosis

Belavgeni, A., Bornstein, S. R., Von Mässenhausen, A., Tonnus, W., Stumpf, J., Meyer, C., Othmar, E., Latk, M., Kanczkowski, W., Kroiss, M., Hantel, C., Hugo, C., Fassnacht, M., Ziegler, C. G., Schally, A. V., Krone, N. P. & Linkermann, A., Oct 29 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 44, p. 22269-22274 6 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

GHRH antagonists support lung endothelial barrier function

Uddin, M. A., Akhter, M. S., Singh, S. S., Kubra, K. T., Schally, A. V., Jois, S. & Barabutis, N., Oct 2 2019, In : Tissue Barriers. 7, 4, 1669989.

Research output: Contribution to journalArticle

8 Scopus citations

Growth Hormone-Releasing Hormone Receptor Antagonist Modulates Lung Inflammation and Fibrosis due to Bleomycin

Zhang, C., Cai, R., Lazerson, A., Delcroix, G., Wangpaichitr, M., Mirsaeidi, M., Griswold, A. J., Schally, A. V. & Jackson, R. M., Oct 1 2019, In : Lung. 197, 5, p. 541-549 9 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Growth hormone-releasing hormone receptor mediates cytokine production in ciliary and iris epithelial cells during LPS-induced ocular inflammation

Ren, J. L., Yu, Q. X., Ma, D., Liang, W. C., Leung, P. Y., Ng, T. K., Chu, W. K., Schally, A. V., Pang, C. P. & Chan, S. O., Apr 1 2019, In : Experimental Eye Research. 181, p. 277-284 8 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Hypothalamic Releasing Hormones

Halmos, G., Dobos, N., Juhasz, E., Szabo, Z. & Schally, A. V., Oct 23 2019, Hormonal Signaling in Biology and Medicine: Comprehensive Modern Endocrinology. Elsevier, p. 43-68 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Stress-inducible-stem cells: a new view on endocrine, metabolic and mental disease?

Bornstein, S. R., Steenblock, C., Chrousos, G. P., Schally, A. V., Beuschlein, F., Kline, G., Krone, N. P., Licinio, J., Wong, M. L., Ullmann, E., Ruiz-Babot, G., Boehm, B. O., Behrens, A., Brennand, A., Santambrogio, A., Berger, I., Werdermann, M., Sancho, R., Linkermann, A., Lenders, J. W. & 2 others, Eisenhofer, G. & Andoniadou, C. L., Jan 1 2019, In : Molecular psychiatry. 24, 1, p. 2-9 8 p.

Research output: Contribution to journalEditorial

8 Scopus citations
2018

Agonists of growth hormone-releasing hormone (GHRH) inhibit human experimental cancers in vivo by down-regulating receptors for GHRH

Schally, A. V., Wang, H., He, J., Cai, R., Sha, W., Popovics, P., Perez, R., Vidaurre, I. & Zhang, X., Nov 20 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 47, p. 12028-12033 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Alterations of tumor microenvironment by nitric oxide impedes castration-resistant prostate cancer growth

Arora, H., Panara, K., Kuchakulla, M., Kulandavelu, S., Burnstein, K. L., Schally, A. V., Hare, J. M. & Ramasamy, R., Oct 30 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 44, p. 11298-11303 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

A new approach to the treatment of acute myeloid leukaemia targeting the receptor for growth hormone-releasing hormone

Jimenez, J. J., Delcanto, G. M., Popovics, P., Perez, A., Vila Granda, A., Vidaurre, I., Cai, R., Rick, F. G., Swords, R. T. & Schally, A. V., Jan 1 2018, (Accepted/In press) In : British Journal of Haematology.

Research output: Contribution to journalArticle

3 Scopus citations

Characterization of luteinizing hormone-releasing hormone receptor type I (LH-RH-I) as a potential molecular target in OCM-1 and OCM-3 human uveal melanoma cell lines

Sipos, E., Dobos, N., Rozsa, D., Fodor, K., Olah, G., Szabo, Z., Szekvolgyi, L., Schally, A. V. & Halmos, G., Feb 22 2018, In : OncoTargets and Therapy. 11, p. 933-941 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Experimental therapy of doxorubicin resistant human uveal melanoma with targeted cytotoxic luteinizing hormone-releasing hormone analog (AN-152)

Oláh, G., Dobos, N., Vámosi, G., Szabó, Z., Sipos, É., Fodor, K., Harda, K., Schally, A. V. & Halmos, G., Oct 15 2018, In : European Journal of Pharmaceutical Sciences. 123, p. 371-376 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Expression of GHRH-R, a Potentially Targetable Biomarker, in Triple-negative Breast Cancer

Khanlari, M., Schally, A. V., Block, N. L. & Nadji, M., Jan 1 2018, In : Applied Immunohistochemistry and Molecular Morphology. 26, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

Expression of progenitor markers is associated with the functionality of a bioartificial adrenal cortex

Balyura, M., Gelfgat, E., Steenblock, C., Androutsellis-Theotokis, A., Ruiz-Babot, G., Guasti, L., Werdermann, M., Ludwig, B., Bornstein, T., Schally, A. V., Brennand, A. & Bornstein, S. R., Mar 2018, In : PloS one. 13, 3, e0194643.

Research output: Contribution to journalArticle

6 Scopus citations

Growth hormone-releasing hormone (GHRH) and its agonists inhibit hepatic and tumoral secretion of IGF-1

Cui, T. & Schally, A. V., Jun 19 2018, In : Oncotarget. 9, 47, p. 28745-28756 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Growth hormone-releasing hormone antagonists reduce prostatic enlargement and inflammation in carrageenan-induced chronic prostatitis

Popovics, P., Cai, R., Sha, W., Rick, F. G. & Schally, A. V., Sep 15 2018, In : Prostate. 78, 13, p. 970-980 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Growth hormone-releasing hormone receptor antagonists modify molecular machinery in the progression of prostate cancer

Muñoz-Moreno, L., Schally, A. V., Prieto, J. C., Carmena, M. J. & Bajo, A. M., Jan 1 2018, (Accepted/In press) In : Prostate.

Research output: Contribution to journalArticle

3 Scopus citations

Induction of apoptosis in pterygium cells by antagonists of growth hormone–releasing hormone receptors

Qin, Y. J., Chu, W. K., Huang, L., Ng, C. H. Y., Chan, T. C. Y., Cao, D., Yang, C., Zhang, L., Huang, S. P., Li, J., Lin, H. L., Li, W. Q., Chen, L., Schally, A. V., Chan, S. O., Zhang, H. Y. & Pang, C. P., Oct 2018, In : Investigative Ophthalmology and Visual Science. 59, 12, p. 5060-5066 7 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Inhibition of experimental small-cell and non-small-cell lung cancers by novel antagonists of growth hormone-releasing hormone

Wang, H., Zhang, X., Vidaurre, I., Cai, R., Sha, W. & Schally, A. V., Jan 1 2018, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

7 Scopus citations

Isolation and characterization of adrenocortical progenitors involved in the adaptation to stress

Steenblock, C., Rubin de Celis, M. F., Delgadillo Silva, L. F., Pawolski, V., Brennand, A., Werdermann, M., Berger, I., Santambrogio, A., Peitzsch, M., Andoniadou, C. L., Schally, A. V. & Bornstein, S. R., Dec 18 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 51, p. 12997-13002 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Magnetoelectric nanoparticles for delivery of antitumor peptides into glioblastoma cells by magnetic fields

Stewart, T. S., Nagesetti, A., Guduru, R., Liang, P., Stimphil, E., Hadjikhani, A., Salgueiro, L., Horstmyer, J., Cai, R., Schally, A. & Khizroev, S., Feb 2018, In : Nanomedicine. 13, 4, p. 423-438 16 p.

Research output: Contribution to journalArticle

6 Scopus citations

P53, GHRH, inflammation and cancer

Barabutis, N., Schally, A. V. & Siejka, A., Nov 1 2018, In : EBioMedicine. 37, p. 557-562 6 p.

Research output: Contribution to journalReview article

Open Access
24 Scopus citations

Regulation of vascular calcification by growth hormone-releasing hormone and its agonists

Shen, J., Zhang, N., Lin, Y. N., Xiang, P. P., Liu, X. B., Shan, P. F., Hu, X. Y., Zhu, W., Tang, Y. L., Webster, K. A., Cai, R., Schally, A. V., Wang, J. & Yu, H., May 2018, In : Circulation research. 122, 10, p. 1395-1408 14 p.

Research output: Contribution to journalArticle

8 Scopus citations

Somatostatin receptors as molecular targets in human uveal melanoma

Harda, K., Szabo, Z., Szabo, E., Olah, G., Fodor, K., Szasz, C., Mehes, G., Schally, A. V. & Halmos, G., 2018, In : Molecules. 23, 7, 1535;.

Research output: Contribution to journalArticle

Structural motif descriptors as a way to elucidate the agonistic or antagonistic activity of growth hormone-releasing hormone peptide analogues

Jeanne Dit Fouque, K., Salgueiro, L. M., Cai, R., Sha, W., Schally, A. V. & Fernandez-Lima, F., Jul 6 2018, In : ACS Omega. 3, 7, p. 7432-7440 9 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2017

Antagonists of growth hormone-releasing hormone inhibit proliferation induced by inflammation in prostatic epithelial cells

Popovics, P., Schally, A. V., Salgueiro, L., Kovacs, K. & Rick, F. G., Feb 7 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 6, p. 1359-1364 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

A Phase II Trial of AEZS-108 in Castration- and Taxane-Resistant Prostate Cancer

Yu, S. S., Athreya, K., Liu, S. V., Schally, A. V., Tsao-Wei, D., Groshen, S., Quinn, D. I., Dorff, T. B., Xiong, S., Engel, J. & Pinski, J., 2017, (Accepted/In press) In : Clinical Genitourinary Cancer.

Research output: Contribution to journalArticle

6 Scopus citations

Concurrence of chromosome 3 and 4 aberrations in human uveal melanoma

Sipos, E., Hegyi, K., Treszl, A., Steiber, Z., Mehes, G., Dobos, N., Fodor, K., Olah, G., Szekvolgyi, L., Schally, A. V. & Halmos, G., Apr 2017, In : Oncology Reports. 37, 4, p. 1927-1934 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Discovery of LHRH and development of LHRH analogs for prostate cancer treatment

Schally, A. V., Block, N. L. & Rick, F. G., Jun 15 2017, In : Prostate. 77, 9, p. 1036-1054 19 p.

Research output: Contribution to journalReview article

8 Scopus citations

Effects of an Antagonistic Analog of Growth Hormone-Releasing Hormone on Endometriosis in a Mouse Model and in Vitro

Köster, F., Jin, L., Shen, Y., Schally, A. V., Cai, R., Block, N. L., Hornung, D., Marschner, G., Rody, A., Engel, J. B. & Finas, D., Nov 1 2017, In : Reproductive Sciences. 24, 11, p. 1503-1511 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Favorable outcome of experimental islet xenotransplantation without immunosuppression in a nonhuman primate model of diabetes

Ludwig, B., Ludwig, S., Steffen, A., Knauf, Y., Zimerman, B., Heinke, S., Lehmann, S., Schubert, U., Schmid, J., Bleyer, M., Schönmann, U., Colton, C. K., Bonifacio, E., Solimena, M., Reichel, A., Schally, A. V., Rotem, A., Barkai, U., Grinberg-Rashi, H., Kaup, F. J. & 3 others, Avni, Y., Jones, P. & Bornstein, S. R., Oct 31 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 44, p. 11745-11750 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Growth hormone-releasing hormone antagonist inhibits the invasiveness of human endometrial cancer cells by downregulating twist and N-cadherin expression

Wu, H. M., Huang, H. Y., Schally, A. V., Chao, A., Chou, H. H., Leung, P. C. K. & Wang, H. S., 2017, In : Oncotarget. 8, 3, p. 4410-4421 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Growth hormone-releasing hormone attenuates cardiac hypertrophy and improves heart function in pressure overload-induced heart failure

Gesmundo, I., Miragoli, M., Carullo, P., Trovato, L., Larcher, V., Di Pasquale, E., Brancaccio, M., Mazzola, M., Villanova, T., Sorge, M., Taliano, M., Gallo, M. P., Alloatti, G., Penna, C., Hare, J. M., Ghigo, E., Schally, A. V., Condorelli, G. & Granata, R., Nov 7 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 45, p. 12033-12038 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Inhibitory Effects of Antagonists of Growth Hormone-Releasing Hormone (GHRH) in Thyroid Cancer

Pópulo, H., Nunes, B., Sampaio, C., Batista, R., Pinto, M. T., Gaspar, T. B., Miranda-Alves, L., Cai, R., Zhang, X. Y., Schally, A. V., Sobrinho-Simões, M. & Soares, P., Dec 1 2017, In : Hormones and Cancer. 8, 5-6, p. 314-324 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Possible Predictive Markers of Response to Therapy in Esophageal Squamous Cell Cancer

Zoltan, L., Farkas, R., Schally, A. V., Pozsgai, E., Papp, A., Bognár, L., Tornoczki, T., Mangel, L. & Bellyei, S., Nov 4 2017, (Accepted/In press) In : Pathology and Oncology Research. p. 1-10 10 p.

Research output: Contribution to journalArticle

Protective effects of agonists of growth hormone-releasing hormone (GHRH) in early experimental diabetic retinopathy

Thounaojam, M. C., Powell, F. L., Patel, S., Gutsaeva, D. R., Tawfik, A., Smith, S. B., Nussbaum, J., Block, N. L., Martin, P. M., Schally, A. V. & Bartoli, M., Dec 12 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 50, p. 13248-13253 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Synthesis and structure-activity studies on novel analogs of human growth hormone releasing hormone (GHRH) with enhanced inhibitory activities on tumor growth

Zarandi, M., Cai, R., Kovacs, M., Popovics, P., Szalontay, L., Cui, T., Sha, W., Jaszberenyi, M., Varga, J., Zhang, X. Y., Block, N. L., Rick, F. G., Halmos, G. & Schally, A. V., Mar 1 2017, In : Peptides. 89, p. 60-70 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

The effects of a growth hormone-releasing hormone antagonist and a gastrin-releasing peptide antagonist on intimal hyperplasia of the carotid artery after balloon injury in a diabetic rat model

Moscona, J. C., Peters, M. N., Schally, A. V., Srivastav, S., Delafontaine, P. & Irimpen, A., Sep 1 2017, In : Artery Research. 19, p. 56-64 9 p.

Research output: Contribution to journalArticle