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2019
20 Citations (Scopus)

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

SpiroMeta Consortium, International COPD Genetics Consortium & Understanding Society Scientific Group, Mar 1 2019, In : Nature genetics. 51, 3, p. 494-505 12 p.

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Phenotype
Lung
Genetic Loci
Genetic Heterogeneity
22 Citations (Scopus)

Inhaled liposomal ciprofloxacin in patients with non-cystic fibrosis bronchiectasis and chronic lung infection with Pseudomonas aeruginosa (ORBIT-3 and ORBIT-4): two phase 3, randomised controlled trials

Haworth, C. S., Bilton, D., Chalmers, J. D., Davis, A. M., Froehlich, J., Gonda, I., Thompson, B., Wanner, A. & O'Donnell, A. E., Mar 1 2019, In : The Lancet Respiratory Medicine. 7, 3, p. 213-226 14 p.

Research output: Contribution to journalArticle

Bronchiectasis
Ciprofloxacin
Pseudomonas aeruginosa
Fibrosis
Randomized Controlled Trials
2018
26 Citations (Scopus)

Blood eosinophil count thresholds and exacerbations in patients with chronic obstructive pulmonary disease

COPDGene and ECLIPSE Investigators, Jun 1 2018, In : Journal of Allergy and Clinical Immunology. 141, 6, p. 2037-2047.e10

Research output: Contribution to journalArticle

Eosinophils
Chronic Obstructive Pulmonary Disease
Biomarkers
Cell Count
Molecular Epidemiology

Why publish scientific meeting proceedings?

Wanner, A., Jan 1 2018, In : Chronic Obstructive Pulmonary Diseases. 5, 4, p. 231-232 2 p.

Research output: Contribution to journalArticle

2017
1 Citation (Scopus)

Airway and Pulmonary β2-Adrenergic Vasodilatory Function in Current Smokers and Never Smokers

Hurwitz, B., Mendes, E., Schmid, A., Parker, M., Arana, J., Gonzalez, A. & Wanner, A., Mar 1 2017, In : Chest. 151, 3, p. 650-657 8 p.

Research output: Contribution to journalArticle

Albuterol
Vascular Resistance
Adrenergic Agents
Lung
Airway Resistance
5 Citations (Scopus)

Biomarkers of collagen turnover are related to annual change in FEV1 in patients with chronic obstructive pulmonary disease within the ECLIPSE study

The Evaluation of COPD Longitudinally to Identify Surrogate Endpoints (ECLIPSE) study investigators, Dec 4 2017, In : BMC Pulmonary Medicine. 17, 1, 164.

Research output: Contribution to journalArticle

Bronchodilator Agents
Chronic Obstructive Pulmonary Disease
Collagen
Biomarkers
Emphysema
2016

A word from the scientific committee: 14th Gordon L. Snider critical issues workshop

Wanner, A., Boucher, R., Cantin, A. & Kelsen, S., Apr 1 2016, In : Annals of the American Thoracic Society. 13, p. S111

Research output: Contribution to journalEditorial

Education
alpha 1-Antitrypsin Deficiency
Cystic Fibrosis
Chronic Obstructive Pulmonary Disease
Autosomal Recessive alpha-1-Antitrypsin Deficiency

Chairs' comments

Wanner, A. & Lungarella, G., Aug 1 2016, In : Annals of the American Thoracic Society. 13, p. S279

Research output: Contribution to journalComment/debate

2015
6 Citations (Scopus)

Acute effect of an inhaled glucocorticosteroid on albuterol-induced bronchodilation in patients with moderately severe asthma

Mendes, E., Cadet, L., Arana, J. & Wanner, A., Apr 1 2015, In : Chest. 147, 4, p. 1037-1042 6 p.

Research output: Contribution to journalArticle

Albuterol
Asthma
Mometasone Furoate
Smooth Muscle
Muscle Relaxation
3 Citations (Scopus)

Effect of airway acidosis and alkalosis on airway vascular smooth muscle responsiveness to albuterol

Cancado, J. E., Mendes, E., Arana, J., Horvath, G., Monzon, M. E., Salathe, M. A. & Wanner, A., Apr 2 2015, In : BMC pharmacology & toxicology. 16, 1, 9.

Research output: Contribution to journalArticle

Alkalosis
Albuterol
Acidosis
Vascular Smooth Muscle
Hyperventilation
13 Citations (Scopus)

Effect of a soy isoflavone supplement on lung function and clinical outcomes in patients with poorly controlled asthma: A randomized clinical trial

Smith, L. J., Kalhan, R., Wise, R. A., Sugar, E. A., Lima, J. J., Irvin, C. G., Dozor, A. J., Holbrook, J. T., Hanania, N., Sockrider, M., Bertrand, L., Atik, M. A., Lopez, B. A., Reibman, J., DiMango, E., Rogers, L., Carapetyan, K., Rivera, K., Bryce-Robinson, N., Scheuerman, M. & 180 others, Fiorino, E., Sundy, J., Green, D., Shah, A., Foss, C., Ghidorzi, J., Allen, S., Mervin-Blake, S., Pangborn, E., Robertson, V. S., Eberlein, N., Land, M., Vickery, B., Wu, E., Jaggers, D., Moy, J., Naureckas, E., Nevin, M., Hixon, J., Brees, A., Gonsalves, Z., Zagaja, V., Kustwin, J., Xu, B., Matthews, T., Robinson, L., Singh, N., Busk, M., Puntenney, P., Busk, N., Hutchins, J., Happel, K. I., Tejedor, R. S., Sandi, M. C., Romaine, C., Burzynski, C. J., Antoine, A., Cruse, J., Katial, R., Hoyte, F., Searing, D., Larson, T., Phillips, N., Currier, H., Blake, K., Lang, J., Mougey, E., Archer, N., Seymour, D., Warde, M., Cohen, R., Santiago, M., Ramdeo, R., Dreyfus, M., Dixon, A. E., Kaminsky, D. A., Lahiri, T., Burns, S. M., Mastronarde, J., Parsons, J., Drake, J., Santiago, J., Cosmar, D., Compton, R. A., Krishnan, S., Boyer, J., Banquet, A., De La Riva-Velasco, E., Lowenthal, D., Gjonaj, S., Kim, Y. C., Traeger, N., Welter, J., Scharbach, M., Siegel, S., Gherson, I., Monchil, L., Formisano, T. M., Williams, J., Castro, M., Bacharier, L., Sumino, K., Tarsi, J. J., Patterson, B., Montgomery, T., Slavin, R. G., Chassaing, D. K., Gerald, L. B., Goodwin, J. L., Brown, M. A., Knox, K. S., Carr, T. F., Berry, C. E., Martinez, F. D., Morgan, W. J., Daines, C. L., Daines, M. O., Grad, R., Ezmigna, D., Vasquez, M. M., Wences, J. A., Lopez, S. S., Priefert, J. C., Varela, M. T., Weese, R., Chee, K., Paco, A., Wanner, A., Lockey, R., Schmid, A., Campos, M. A., King, M., Mendes, E., Rebolledo, P. D., Arana, J., Cadet, L., McCrery, R., Croker, S. M., McCullough, S., Salzman, G., Abdeljalil, A., Pyszczynski, D., Bhat, A., Haney, P., Wasserman, S., Ramsdell, J., Soler, X., Kinninger, K., Ferguson, P., Martineau, A., Ung, S., Greene, T., Teague, W. G., Wavell, K. W., Wolf, D., Thompson-Batt, D., Bailey, W. C., Anthonisen, N., Yasin, R., Amend-Libercci, D., Adler, A., Casper, A. S., Daniel, M., Hart, A., Lears, A., Leatherman, G., Nowakowski, D., Prusakowski, N., Rayapudi, S., Rea, A., Saams, J., Shade, D., Thurman, A., Wei, C., Newcomer, A., Bime, C., Brown, E., Levine, C., Roettger, S., Wu, N., Shen, W., Wang, L., Ukken, J., Lazarus, S. C., Calhoun, W. J., Cloutier, M., Kahrilas, P., McWilliams, B., Rogatko, A., Sorkness, C., Sicherer, S., Weinmann, G., Freemer, M., Smith, R., Taggart, V., Webber, L., Zheng, G., Lancet, E., Edelman, N. H. & Rappaport, S., May 26 2015, In : JAMA - Journal of the American Medical Association. 313, 20, p. 2033-2043 11 p.

Research output: Contribution to journalArticle

Isoflavones
Asthma
Randomized Controlled Trials
Lung
Placebos
131 Citations (Scopus)

Hospitalized exacerbations of COPD: Risk factors and outcomes in the ECLIPSE cohort

ECLIPSE Investigators, Apr 1 2015, In : Chest. 147, 4, p. 999-1007 9 p.

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Biomarkers
Hospitalization
Recurrence
Mortality
2014
12 Citations (Scopus)

Appropriateness of newborn screening for α1-antitrypsin deficiency

Teckman, J., Pardee, E., Howell, R., Mannino, D., Sharp, R. R., Brantly, M., Wanner, A. & Lamson, J., Feb 1 2014, In : Journal of Pediatric Gastroenterology and Nutrition. 58, 2, p. 199-203 5 p.

Research output: Contribution to journalArticle

Newborn Infant
Lung Diseases
Liver Diseases
Smoking
Patient Protection and Affordable Care Act
13 Citations (Scopus)

DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease

the COPDGene and ECLIPSE Investigators, Aug 20 2014, In : Respiratory Research. 15, 1, 97.

Research output: Contribution to journalArticle

Total Lung Capacity
Dyneins
Chronic Obstructive Pulmonary Disease
Linear Models
Kartagener Syndrome
31 Citations (Scopus)

Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease

COPDGene and ECLIPSE Investigators, Sep 21 2014, In : Respiratory Research. 15, 1, 113.

Research output: Contribution to journalArticle

Chronic Bronchitis
Genetic Predisposition to Disease
Chronic Obstructive Pulmonary Disease
Spirometry
Genome
7 Citations (Scopus)

Immediate antiinflammatory effects of inhaled budesonide in patients with asthma

Mendes, E., Rebolledo, P., Campos, M. A. & Wanner, A., Jan 1 2014, In : Annals of the American Thoracic Society. 11, 5, p. 706-711 6 p.

Research output: Contribution to journalArticle

Budesonide
Anti-Inflammatory Agents
Asthma
Inflammation
Spirometry
61 Citations (Scopus)

The multi-ethnic study of atherosclerosis lung/snp health association resource study

Manichaiku, A., Hoffman, E. A., Smolonska, J., Gao, W., Cho, M. H., Baumhauer, H., Budoff, M., Austin, J. H. M., Washko, G. R., Carr, J. J., Kaufman, J. D., Pottinger, T., Powell, C. A., Wijmenga, C., Zanen, P., Groen, H. J. M., Postma, D. S., Wanner, A., Rouhani, F. N., Brantly, M. L. & 14 others, Powell, R., Smith, B. M., Rabinowitz, D., Raffel, L. J., Hinckley Stukovsky, K. D., Crapo, J. D., Beaty, T. H., Hokanson, J. E., Silverman, E. K., Dupuis, J., O'Connor, G. T., Boezen, H. M., Rich, S. S. & Barr, R. G., Feb 15 2014, In : American Journal of Respiratory and Critical Care Medicine. 189, 4, p. 408-418 11 p.

Research output: Contribution to journalArticle

Health Resources
Emphysema
Atherosclerosis
Lung
Mannosidases
2013
5 Citations (Scopus)

Airway vascular endothelial function in healthy smokers without systemic endothelial dysfunction

Mendes, E., Cancado, J. E. D., Rebolledo, P., Arana, J., Parker, M., Gonzalez, A., Hurwitz, B. & Wanner, A., Jun 1 2013, In : Chest. 143, 6, p. 1733-1739 7 p.

Research output: Contribution to journalArticle

Blood Vessels
Vasodilation
Inflammation
Albuterol
Smoke

A metagenomic approach to the airways microbiome of chronic obstructive pulmonary disease (COPD)

Fernandez, M., Jaric, M., Schneper, L., Segal, J., Silva-Herzog, E., Campos, M. A., Fishman, J., Salathe, M. A., Wanner, A., Infante, J., Mathee, K. & Narasimhan, G., Aug 5 2013, Proceedings - 29th Southern Biomedical Engineering Conference, SBEC 2013. p. 151-152 2 p. 6525721

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Pulmonary diseases
Bioinformatics

Purpose of the conference

MacNee, W., Fahy, J., Nicod, L. & Wanner, A., Dec 1 2013, In : Annals of the American Thoracic Society. 10, SUPPL

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Asthma
2012
8 Citations (Scopus)

Acute effects of salmeterol and fluticasone propionate alone and in combination on airway blood flow in patients with asthma

Mendes, E., Rebolledo, P. & Wanner, A., May 1 2012, In : Chest. 141, 5, p. 1184-1189 6 p.

Research output: Contribution to journalArticle

Asthma
Vascular Smooth Muscle
Vasodilator Agents
Vasodilation
Smooth Muscle

Effect of brief exercise on airway blood flow in subjects with and without asthma

Mendes, E., Lit, L., Horvath, G., Rebolledo, P. & Wanner, A., Oct 1 2012, In : Journal of Exercise Physiology Online. 15, 5, p. 10-17 8 p.

Research output: Contribution to journalArticle

Vasodilation
Asthma
Endothelium
Perfusion
Hyperventilation
12 Citations (Scopus)

Novel therapeutic uses of alpha-1 antitrypsin: A window to the future

Wanner, A., Arce, A. D. & Pardee, E., Dec 1 2012, In : COPD: Journal of Chronic Obstructive Pulmonary Disease. 9, 6, p. 583-588 6 p.

Research output: Contribution to journalArticle

alpha 1-Antitrypsin
Therapeutic Uses
alpha 1-Antitrypsin Deficiency
Therapeutics
Serine Proteinase Inhibitors
2011
22 Citations (Scopus)

Aerosolized red tide toxins (brevetoxins) and asthma: Continued health effects after 1h beach exposure

Kirkpatrick, B., Fleming, L. E., Bean, J. A., Nierenberg, K., Backer, L. C., Cheng, Y. S., Pierce, R., Reich, A., Naar, J., Wanner, A., Abraham, W. M., Zhou, Y., Hollenbeck, J. & Baden, D. G., Jan 1 2011, In : Harmful Algae. 10, 2, p. 138-143 6 p.

Research output: Contribution to journalArticle

brevetoxins
red tide
asthma
algal blooms
toxin
6 Citations (Scopus)

Florida red tide toxins (brevetoxins) and longitudinal respiratory effects in asthmatics

Bean, J. A., Fleming, L. E., Kirkpatrick, B., Backer, L. C., Nierenberg, K., Reich, A., Cheng, Y. S., Wanner, A., Benson, J., Naar, J., Pierce, R., Abraham, W. M., Kirkpatrick, G., Hollenbeck, J., Zaias, J., Mendes, E. & Baden, D. G., Sep 1 2011, In : Harmful Algae. 10, 6, p. 744-748 5 p.

Research output: Contribution to journalArticle

brevetoxins
red tide
lung function
algal blooms
toxin
4 Citations (Scopus)

Orthodeoxia platypnea syndrome in a patient with lipomatous hypertrophy of the interatrial septum due to long-term steroid use

Bokhari, S. S. I., Willens, H. J., Lowery, M., Wanner, A. & De Marchena, E., Feb 1 2011, In : Chest. 139, 2, p. 443-445 3 p.

Research output: Contribution to journalArticle

Patent Foramen Ovale
Hypertrophy
Steroids
Pulmonary Eosinophilia
Oximetry

Purpose of the conference

MacNee, W., Fahy, J. V., Nicod, L. & Wanner, A., Nov 1 2011, In : Proceedings of the American Thoracic Society. 8, 6

Research output: Contribution to journalArticle

16 Citations (Scopus)

Rapid nongenomic actions of inhaled corticosteroids on long-acting β 2-agonist transport in the airway

Horvath, G., Mendes, E., Schmid, N., Schmid, A., Conner, G. E., Fregien, N. L., Salathe, M. A. & Wanner, A., Dec 1 2011, In : Pulmonary Pharmacology and Therapeutics. 24, 6, p. 654-659 6 p.

Research output: Contribution to journalArticle

Adrenal Cortex Hormones
Smooth Muscle Myocytes
Muscle
Cells
Bronchodilator Agents
85 Citations (Scopus)

Review of Florida red tide and human health effects

Fleming, L. E., Kirkpatrick, B., Backer, L. C., Walsh, C. J., Nierenberg, K., Clark, J., Reich, A., Hollenbeck, J., Benson, J., Cheng, Y. S., Naar, J., Pierce, R., Bourdelais, A. J., Abraham, W. M., Kirkpatrick, G., Zaias, J., Wanner, A., Mendes, E., Shalat, S., Hoagland, P. & 6 others, Stephan, W., Bean, J., Watkins, S., Clarke, T., Byrne, M. M. & Baden, D. G., Jan 1 2011, In : Harmful Algae. 10, 2, p. 224-233 10 p.

Research output: Contribution to journalArticle

red tide
algal blooms
toxin
human health
interdisciplinary approach