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  • Ralph L Sacco

Arterial wave reflection and subclinical left ventricular systolic dysfunction

Russo, C., Jin, Z., Takei, Y., Hasegawa, T., Koshaka, S., Palmieri, V., Elkind, M. S. V., Homma, S., Sacco, R. L. & Di Tullio, M. R., Mar 2011, In : Journal of hypertension. 29, 3, p. 574-582 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Aspirin Does Not Increase Heart Failure Events in Heart Failure Patients: From the WARCEF Trial

WARCEF Investigators, Aug 2017, In : JACC: Heart Failure. 5, 8, p. 603-610 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Association between Blood Pressure and Later-Life Cognition among Black and White Individuals

Levine, D. A., Gross, A. L., Briceño, E. M., Tilton, N., Kabeto, M. U., Hingtgen, S. M., Giordani, B. J., Sussman, J. B., Hayward, R. A., Burke, J. F., Elkind, M. S. V., Manly, J. J., Moran, A. E., Kulick, E. R., Gottesman, R. F., Walker, K. A., Yano, Y., Gaskin, D. J., Sidney, S., Yaffe, K. & 5 others, Sacco, R. L., Wright, C. B., Roger, V. L., Allen, N. B. & Galecki, A. T., Jan 1 2020, (Accepted/In press) In : JAMA Neurology.

Research output: Contribution to journalArticle

2 Scopus citations

Association between carotid artery function and structure in the Northern Manhattan Study

Della-Morte, D., Gardener, H., Dong, C., Markert, M., Cabral, D., Elkind, M. S. V., Sacco, R. L. & Rundek, T., Apr 16 2018, In : Frontiers in Neurology. 9, APR, 246.

Research output: Contribution to journalArticle

3 Scopus citations

Association between Central Blood Pressure and Subclinical Cerebrovascular Disease in Older Adults

Matsumoto, K., Jin, Z., Homma, S., Elkind, M. S. V., Rundek, T., Mannina, C., Lee, T. C., Yoshita, M., Decarli, C., Wright, C. B., Sacco, R. L. & Di Tullio, M. R., Feb 1 2020, In : Hypertension. p. 580-587 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Association between heart rate and subclinical cerebrovascular disease in the elderly

Nakanishi, K., Jin, Z., Homma, S., Elkind, M. S. V., Rundek, T., Lee, S. C., Tugcu, A., Yoshita, M., DeCarli, C., Wright, C. B., Sacco, R. L. & Di Tullio, M. R., 2018, In : Stroke. 49, 2, p. 319-324 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Association between mortality and implantable cardioverter-defibrillators by aetiology of heart failure: a propensity-matched analysis of the WARCEF trial

for the WARCEF Investigators, Apr 2019, In : ESC Heart Failure. 6, 2, p. 297-307 11 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Association between Northern Manhattan study global vascular risk score and successful aging

Warsch, J. R. L., Rundek, T., Paik, M. C., Elkind, M. S. V., Sacco, R. L. & Wright, C. B., Apr 2013, In : Journal of the American Geriatrics Society. 61, 4, p. 519-524 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Association between PNPLA3 rs738409 G variant and MRI cerebrovascular disease biomarkers

Parikh, N. S., Dueker, N., Varela, D., Del Brutto, V. J., Rundek, T., Wright, C. B., Sacco, R. L., Elkind, M. S. V. & Gutierrez, J., Sep 15 2020, In : Journal of the Neurological Sciences. 416, 116981.

Research output: Contribution to journalArticle

Association between Serum Tumor Necrosis Factor Receptor 1 and Trajectories of Functional Status

Dhamoon, M. S., Cheung, Y. K., Moon, Y. P., Wright, C. B., Willey, J. Z., Sacco, R. L. & Elkind, M. S. V., Jul 1 2017, In : American journal of epidemiology. 186, 1, p. 11-20 10 p.

Research output: Contribution to journalArticle

Association between sleep duration and the mini-mental score: The northern manhattan study

Ramos, A. R., Dong, C., Elkind, M. S. V., Boden-Albala, B., Sacco, R. L., Rundek, T. & Wright, C. B., Jul 15 2013, In : Journal of Clinical Sleep Medicine. 9, 7, p. 669-673 5 p.

Research output: Contribution to journalArticle

48 Scopus citations

Association between social isolation and left ventricular mass

Rodriguez, C. J., Elkind, M. S. V., Clemow, L., Jin, Z., Di Tullio, M., Sacco, R. L., Homma, S. & Boden-Albala, B., Feb 2011, In : American Journal of Medicine. 124, 2, p. 164-170 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Association Between Subclinical Brain Infarcts and Functional Decline Trajectories

Dhamoon, M. S., Cheung, Y. K., DeRosa, J. T., Gutierrez, J., Moon, Y. P., Sacco, R. L., Elkind, M. S. V. & Wright, C. B., Nov 2018, In : Journal of the American Geriatrics Society. 66, 11, p. 2144-2150 7 p.

Research output: Contribution to journalArticle

Association between variations in coagulation system genes and carotid plaque

Della-Morte, D., Beecham, A., Dong, C., Wang, L., McClendon, M. S., Gardener, H., Blanton, S. H., Sacco, R. L. & Rundek, T., Dec 15 2012, In : Journal of the Neurological Sciences. 323, 1-2, p. 93-98 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Association of blood pressure control level with left ventricular morphology and function and with subclinical cerebrovascular disease

Nakanishi, K., Jin, Z., Homma, S., Elkind, M. S. V., Rundek, T., Tugcu, A., Sacco, R. L. & Di Tullio, M. R., Aug 1 2017, In : Journal of the American Heart Association. 6, 8, e006246.

Research output: Contribution to journalArticle

5 Scopus citations

Association of body size metrics with left atrial phasic volumes and reservoir function in the elderly

Tugcu, A., Russo, C., Jin, Z., Homma, S., Nakanishi, K., Elkind, M. S. V., Rundek, T., Sacco, R. L. & Di Tullio, M. R., Oct 1 2018, In : European Heart Journal Cardiovascular Imaging. 19, 10, p. 1157-1164 8 p.

Research output: Contribution to journalArticle

Association of Cardiovascular Health With Subclinical Disease and Incident Events: The Multi-Ethnic Study of Atherosclerosis

Polonsky, T. S., Ning, H., Daviglus, M. L., Liu, K., Burke, G. L., Cushman, M., Eng, J., Folsom, A. R., Lutsey, P. L., Nettleton, J. A., Post, W. S., Sacco, R. L., Szklo, M. & Lloyd-Jones, D. M., Mar 2017, In : Journal of the American Heart Association. 6, 3, e004894.

Research output: Contribution to journalArticle

21 Scopus citations

Association of chronic kidney disease with impaired left atrial reservoir function: A community-based cohort study

Nakanishi, K., Jin, Z., Russo, C., Homma, S., Elkind, M. S. V., Rundek, T., Tugcu, A., Sacco, R. L. & Di Tullio, M. R., Mar 1 2017, In : European Journal of Preventive Cardiology. 24, 4, p. 392-398 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Association of improved outcome in acute ischaemic stroke patients with atrial fibrillation who receive early antithrombotic therapy: Analysis from VISTA

for the VISTA collaborators, Jul 1 2015, In : European Journal of Neurology. 22, 7, p. 1048-1055 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

Association of quality of life with anticoagulant control in patients with heart failure: The Warfarin and Aspirin in Reduced Cardiac Ejection Fraction (WARCEF) trial

Shaffer, J. A., Thompson, J. L. P., Cheng, B., Ye, S., Lip, G. Y. H., Mann, D. L., Sacco, R. L., Pullicino, P. M., Freudenberger, R. S., Graham, S., Mohr, J. P., Labovitz, A. J., Estol, C. J., Lok, D. J., Ponikowski, P., Anker, S. D., Di Tullio, M. R. & Homma, S., Dec 15 2014, In : International Journal of Cardiology. 177, 2, p. 715-717 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Association of serum soluble Receptor for Advanced Glycation End-products with subclinical cerebrovascular disease: The Northern Manhattan Study (NOMAS)

Hudson, B. I., Moon, Y. P., Kalea, A. Z., Khatri, M., Marquez, C., Schmidt, A. M., Paik, M. C., Yoshita, M., Sacco, R. L., DeCarli, C., Wright, C. B. & Elkind, M. S. V., May 2011, In : Atherosclerosis. 216, 1, p. 192-198 7 p.

Research output: Contribution to journalArticle

51 Scopus citations

Association of the sirtuin and mitochondrial uncoupling protein genes with carotid intima-media thickness

Della-Morte, D., Dong, C., Bartels, S., Cabral, D., Blanton, S. H., Sacco, R. L. & Rundek, T., Nov 2012, In : Translational Research. 160, 5, p. 389-390 2 p.

Research output: Contribution to journalComment/debate

9 Scopus citations

Association of the sirtuin and mitochondrial uncoupling protein genes with carotid plaque

Dong, C., Della-Morte, D., Wang, L., Cabral, D., Beecham, A., McClendon, M. S., Luca, C. C., Blanton, S. H., Sacco, R. L. & Rundek, T., Nov 7 2011, In : PloS one. 6, 11, e27157.

Research output: Contribution to journalArticle

38 Scopus citations
11 Scopus citations

Atherosclerotic plaques in the aortic arch and subclinical cerebrovascular disease

Tugcu, A., Jin, Z., Homma, S., Elkind, M. S. V., Rundek, T., Yoshita, M., Decarli, C., Nakanishi, K., Shames, S., Wright, C. B., Sacco, R. L. & Di Tullio, M. R., Nov 1 2016, In : Stroke. 47, 11, p. 2813-2819 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Atlas of the global burden of stroke (1990-2013): The GBD 2013 study

GBD 2013 Stroke Panel Experts Group, Oct 1 2015, In : Neuroepidemiology. 45, 3, p. 230-236 7 p.

Research output: Contribution to journalArticle

121 Scopus citations

Automatic identification of variables in epidemiological datasets using logic regression

Lorenz, M. W., Abdi, N. A., Scheckenbach, F., Pflug, A., Bülbül, A., Catapano, A. L., Agewall, S., Ezhov, M., Bots, M. L., Kiechl, S., Orth, A., Norata, G. D., Empana, J. P., Lin, H. J., McLachlan, S., Bokemark, L., Ronkainen, K., Amato, M., Schminke, U., Srinivasan, S. R. & 72 others, Lind, L., Kato, A., Dimitriadis, C., Przewlocki, T., Okazaki, S., Stehouwer, C. D. A., Lazarevic, T., Willeit, P., Yanez, D. N., Steinmetz, H., Sander, D., Poppert, H., Desvarieux, M., Ikram, M. A., Bevc, S., Staub, D., Sirtori, C. R., Iglseder, B., Engström, G., Tripepi, G., Beloqui, O., Lee, M. S., Friera, A., Xie, W., Grigore, L., Plichart, M., Su, T. C., Robertson, C., Schmidt, C., Tuomainen, T. P., Veglia, F., Völzke, H., Nijpels, G., Jovanovic, A., Willeit, J., Sacco, R. L., Franco, O. H., Hojs, R., Uthoff, H., Hedblad, B., Park, H. W., Suarez, C., Zhao, D., Ducimetiere, P., Chien, K. L., Price, J. F., Bergström, G., Kauhanen, J., Tremoli, E., Dörr, M., Berenson, G., Papagianni, A., Kablak-Ziembicka, A., Kitagawa, K., Dekker, J. M., Stolic, R., Polak, J. F., Sitzer, M., Bickel, H., Rundek, T., Hofman, A., Ekart, R., Frauchiger, B., Castelnuovo, S., Rosvall, M., Zoccali, C., Landecho, M. F., Bae, J. H., Gabriel, R., Liu, J., Baldassarre, D. & Kavousi, M., Apr 13 2017, In : BMC Medical Informatics and Decision Making. 17, 1, 40.

Research output: Contribution to journalArticle

Baseline and longitudinal increases in diastolic blood pressure are associated with greater white matter hyperintensity volume: The northern manhattan study

Marcus, J., Gardener, H., Rundek, T., Elkind, M. S. V., Sacco, R. L., Decarli, C. & Wright, C. B., Sep 2011, In : Stroke. 42, 9, p. 2639-2641 3 p.

Research output: Contribution to journalArticle

44 Scopus citations

Benefit of warfarin compared with aspirin in patients with heart failure in sinus rhythm: A subgroup analysis of WARCEF, a randomized controlled trial

Homma, S., Thompson, J. L. P., Sanford, A. R., Mann, D. L., Sacco, R. L., Levin, B., Pullicino, P. M., Freudenberger, R. S., Teerlink, J. R., Graham, S., Mohr, J. P., Massie, B. M., Labovitz, A. J., Di Tullio, M. R., Gabriel, A. P., Lip, G. Y. H., Estol, C. J., Lok, D. J., Ponikowski, P. & Anker, S. D., Sep 2013, In : Circulation: Heart Failure. 6, 5, p. 988-997 10 p.

Research output: Contribution to journalArticle

34 Scopus citations

Big Data Approaches to Phenotyping Acute Ischemic Stroke Using Automated Lesion Segmentation of Multi-Center Magnetic Resonance Imaging Data

Wu, O., Winzeck, S., Giese, A. K., Hancock, B. L., Etherton, M. R., Bouts, M. J. R. J., Donahue, K., Schirmer, M. D., Irie, R. E., Mocking, S. J. T., McIntosh, E. C., Bezerra, R., Kamnitsas, K., Frid, P., Wasselius, J., Cole, J. W., Xu, H., Holmegaard, L., Jiménez-Conde, J., Lemmens, R. & 22 others, Lorentzen, E., McArdle, P. F., Meschia, J. F., Roquer, J., Rundek, T., Sacco, R. L., Schmidt, R., Sharma, P., Slowik, A., Stanne, T. M., Thijs, V., Vagal, A., Woo, D., Bevan, S., Kittner, S. J., Mitchell, B. D., Rosand, J., Worrall, B. B., Jern, C., Lindgren, A. G., Maguire, J. & Rost, N. S., Jul 1 2019, In : Stroke. 50, 7, p. 1734-1741 8 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
38 Scopus citations

Bleeding Risk and Antithrombotic Strategy in Patients With Sinus Rhythm and Heart Failure With Reduced Ejection Fraction Treated With Warfarin or Aspirin

Ye, S., Cheng, B., Lip, G. Y. H., Buchsbaum, R., Sacco, R. L., Levin, B., Di Tullio, M. R., Qian, M., Mann, D. L., Pullicino, P. M., Freudenberger, R. S., Teerlink, J. R., Mohr, J. P., Graham, S., Labovitz, A. J., Estol, C. J., Lok, D. J., Ponikowski, P., Anker, S. D., Thompson, J. L. P. & 1 others, Homma, S., Sep 15 2015, In : American Journal of Cardiology. 116, 6, p. 904-912 9 p., 21244.

Research output: Contribution to journalArticle

6 Scopus citations

Blood pressure control in aging predicts cerebral atrophy related to small-vessel white matter lesions

Kern, K. C., Wright, C. B., Bergfield, K. L., Fitzhugh, M. C., Chen, K., Moeller, J. R., Nabizadeh, N., Elkind, M. S. V., Sacco, R. L., Stern, Y., DeCarli, C. S. & Alexander, G. E., May 15 2017, In : Frontiers in Aging Neuroscience. 9, MAY, 132.

Research output: Contribution to journalArticle

7 Scopus citations

Brain arterial diameters and cognitive performance: The Northern Manhattan study

Gutierrez, J., Kulick, E., Park Moon, Y., Dong, C., Cheung, K., Ahmet, B., Stern, Y., Alperin, N., Rundek, T., Sacco, R. L., Wright, C. B. & Elkind, M. S. V., Apr 1 2018, In : Journal of the International Neuropsychological Society. 24, 4, p. 335-346 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Brain Arterial Diameters as a Risk Factor for Vascular Events

Gutierrez, J., Cheung, K., Bagci, A., Rundek, T., Alperin, N., Sacco, R. L., Wright, C. B. & Elkind, M. S. V., Aug 6 2015, In : Journal of the American Heart Association. 4, 8, p. e002289

Research output: Contribution to journalArticle

12 Scopus citations

Brain arterial dilatation modifies the association between extracranial pulsatile hemodynamics and brain perivascular spaces: the Northern Manhattan Study

Gutierrez, J., DiTullio, M., K Cheung, Y. K., Alperin, N., Bagci, A., L Sacco, R., B Wright, C., SV Elkind, M. & Rundek, T., Jul 1 2019, In : Hypertension Research. 42, 7, p. 1019-1028 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Brain health and shared risk factors for dementia and stroke

Gardener, H., Wright, C. B., Rundek, T. & Sacco, R. L., Nov 1 2015, In : Nature Reviews Neurology. 11, 11, p. 651-657 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

Brain perivascular spaces as biomarkers of vascular risk: RESULTS from the Northern Manhattan Study

Gutierrez, J., Elkind, M. S. V., Dong, C., Di Tullio, M., Rundek, T., Sacco, R. L. & Wright, C. B., May 2017, In : American Journal of Neuroradiology. 38, 5, p. 862-867 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Brain Volume: An Important Determinant of Functional Outcome After Acute Ischemic Stroke

MRI-GENIE and GISCOME Investigators and the International Stroke Genetics Consortium, May 2020, In : Mayo Clinic Proceedings. 95, 5, p. 955-965 11 p.

Research output: Contribution to journalArticle

Cardiovascular health among diverse Hispanics/Latinos: Hispanic Community Health Study/Study of Latinos (HCHS/SOL) results

González, H. M., Tarraf, W., Rodríguez, C. J., Gallo, L. C., Sacco, R. L., Talavera, G. A., Heiss, G., Kizer, J. R., Hernandez, R., Davis, S., Schneiderman, N., Daviglus, M. L. & Kaplan, R. C., 2016, In : American Heart Journal. 176, p. 134-144 11 p.

Research output: Contribution to journalArticle

37 Scopus citations

Cardiovascular health status among Caribbean Hispanics living in northern Manhattan and Ecuadorian natives/mestizos in rural coastal Ecuador: A comparative study

Del Brutto, O. H., Dong, C., Rundek, T., Elkind, M. S. V., Del Brutto, V. J. & Sacco, R. L., Aug 2013, In : Journal of Community Health. 38, 4, p. 634-641 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Carotid intima-media thickness is associated with white matter hyperintensities the Northern Manhattan Study

Della-Morte, D., Dong, C., Markert, M. S., Elkind, M. S. V., Sacco, R. L., Wright, C. B. & Rundek, T., 2018, In : Stroke. 49, 2, p. 304-311 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Carotid Intima-Media thickness progression and risk of vascular events in people with Diabetes: Results from the PROG-IMT collaboration

Lorenz, M. W., Price, J. F., Robertson, C., Bots, M. L., Polak, J. F., Poppert, H., Kavousi, M., Dorr, M., Stensland, E., Ducimetiere, P., Ronkainen, K., Kiechl, S., Sitzer, M., Rundek, T., Lind, L., Liu, J., Bergstrom, G., Grigore, L., Bokemark, L., Friera, A. & 33 others, Yanez, D., Bickel, H., Ikram, M. A., Volzke, H., Johnsen, S. H., Empana, J. P., Tuomainen, T. P., Willeit, P., Steinmetz, H., Desvarieux, M., Xie, W., Schmidt, C., Norata, G. D., Suarez, C., Sander, D., Hofman, A., Schminke, U., Mathiesen, E., Plichart, M., Kauhanen, J., Willeit, J., Sacco, R. L., McLachlan, S., Zhao, D., Fagerberg, B., Catapano, A. L., Gabriel, R., Franco, O. H., Bulbul, A., Scheckenbach, F., Pflug, A., Gao, L. & Thompson, S. G., Oct 2015, In : Diabetes care. 38, 10, p. 1921-1929 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

Carotid plaque and candidate genes related to inflammation and endothelial function in hispanics from Northern Manhattan

Gardener, H., Beecham, A., Cabral, D., Yanuck, D., Slifer, S., Wang, L., Blanton, S. H., Sacco, R. L., Juo, S. H. H. & Rundek, T., Apr 2011, In : Stroke. 42, 4, p. 889-896 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Cerebral Microbleeds, Vascular Risk Factors, and Magnetic Resonance Imaging Markers: The Northern Manhattan Study

Caunca, M. R., Del Brutto, V., Gardener, H., Shah, N., Dequatre-Ponchelle, N., Cheung, Y. K., Elkind, M. S. V., Brown, T. R., Cordonnier, C., Sacco, R. L. & Wright, C. B., Sep 2016, In : Journal of the American Heart Association. 5, 9, e003477.

Research output: Contribution to journalArticle

22 Scopus citations

Cerebral white matter disease and functional decline in older adults from the Northern Manhattan Study: A longitudinal cohort study

Dhamoon, M. S., Cheung, Y. K., Moon, Y., DeRosa, J., Sacco, R., Elkind, M. S. V. & Wright, C. B., Mar 2018, In : PLoS Medicine. 15, 3, e1002529.

Research output: Contribution to journalArticle

4 Scopus citations

Cerebrovascular disease

Sacco, R. L. & Rundek, T., Feb 1 2012, In : Current Opinion in Neurology. 25, 1, p. 1-4 4 p.

Research output: Contribution to journalReview article

2 Scopus citations

Cerebrovascular pulsatility in patients with sleep-disordered breathing

Ramos, A. R., Cabral, D., Lee, D. J., Sacco, R. L. & Rundek, T., May 2013, In : Sleep and Breathing. 17, 2, p. 723-726 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Cervical arterial dissections and association with cervical manipulative therapy: A statement for healthcare professionals from the American Heart Association/American Stroke Association

Biller, J., Sacco, R. L., Albuquerque, F. C., Demaerschalk, B. M., Fayad, P., Long, P. H., Noorollah, L. D., Panagos, P. D., Schievink, W. I., Schwartz, N. E., Shuaib, A., Thaler, D. E. & Tirschwell, D. L., Oct 12 2014, In : Stroke. 45, 10, p. 3155-3174 20 p.

Research output: Contribution to journalArticle

85 Scopus citations

CHA2DS2-VASc score and adverse outcomes in patients with heart failure with reduced ejection fraction and sinus rhythm

on behalf of the WARCEF Investigators, Oct 1 2016, In : European Journal of Heart Failure. 18, 10, p. 1261-1266 6 p.

Research output: Contribution to journalArticle

15 Scopus citations