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2019
115 Citations (Scopus)

Antithrombotic therapy after acute coronary syndrome or PCI in atrial fibrillation

Lopes, R. D., Heizer, G., Aronson, R., Vora, A. N., Massaro, T., Mehran, R., Goodman, S. G., Windecker, S., Darius, H., Li, J., Averkov, O., Bahit, M. C., Berwanger, O., Budaj, A., Hijazi, Z., Parkhomenko, A., Sinnaeve, P., Storey, R. F., Thiele, H., Vinereanu, D. & 486 others, Granger, C. B., Alexander, J. H., Hrabar, A. D., Caccavo, A., Licheri, A., Alvarisqueta, A. F., Abud, A. M., Estrada, C., Sueldo, C. P., Montenegro, E., Duronto, E. A., Blanco, F. L., Berra, F. C., Ferré Pácora, F. A., Lopez, G. M., Calvo, G., Azize, G. M., Luquez, H. A., Ramos, H., Colombo, H. R., Guetta, J. N., Resk, J. H., Medrano, J. C., Costabel, J. P., Carbajales, J., Schiavi, L. B., Saggia, L. I., Oliva, M. A., Casas, M., Snitman, M., Litvak Bruno, M. R., Cluigt, N., Vita, N. A., Guzman, P. N., Zangroniz, P. D., Villarreal, R. A., Bonato, R. R., Nani, S., Sassone, S. A., Macin, S. M., Arias, V. E., Alexopoulos, C., Brieger, D., Colquhoun, D., Heddle, W. F., Podczeck-Schweighofer, A., Ebner, C., Scherr, D., Lang, I. M., Huber, K., Guedes, A., Convens, C., Cools, F., Vercammen, J., Bartunek, J., Rossenbacker, T., Pereira, A. H., Kormann, A. M., Freitas, A. F., Fonseca, A. G. T., de Quadros, A., Janella, B. L., Kalil, C. A. A., Rodrigues, C. S., Precoma, D. B., Ramacciotti, E., Resende, E. S., Figueiredo, E. L., Manenti, E. R., Costa, F. A. D., Feitosa, G., Reis, H. J. L., Ribeiro, H. B., de Moraes, J. B. M. X., Dantas, J. M. M., Nicolau, J. C., Saraiva, J. F. K., Reolão, J., Piegas, L. S., Oliveira, L. F. A., Ritt, L. E. F., Braile, M. C. V. B., Dracoulakis, M. A., de Santos, M. O. N., Leães, P. E., Filho, P. P., Rech, R. L., Ueda, R., Silvestrini, T. L., Michalaros, Y. L., Manolova, A., Mihov, A. K., Yatseva, B., Velikov, C., Raev, D. H., Markov, D., Vassilev, D., Georgiev, E., Benov, H. O., Daskalov, I., Petrov, I. P., Milanova, M., Shehova-Yankova, N. S., Lazov, P. V., Beleva, S., Marchev, S. T., Gelev, V. L., Tyrrell, B., Wong, B., Dion, D., LaFlamme, D., Rupka, D. W., Shukla, D., Sabbah, E., Nadra, I. J., Bata, I., Cherry, J. M., Toleva, O., Dehghani, P., Vijayaraghavan, R., Welsh, R., Bagur, R., Labonte, R. E., Vizel, S., Fort, S., Huynh, T., Quan, V. H., Pesant, Y., Isaza, D., Accini Mendoza, J. L., Gomez, J. E., Jaramillo Gomez, N. I., Knezevic, A., Ruzic, A., Horvat, D., Milicic, D., Selthofer-Relatic, K., Pesek, K., Pravecek, M. K., Kovacic, M., Manola, S., Persic, V., Alan, D., Belohlavek, J., Larsen, C. T., Brønnum-Schou, J., Veien, K. T., Christensen, L. S., Maeng, M., Steffensen, R., Angoulvant, D., Beygui, F., Range, G., Cayla, G., Aupetit, J. F., Elbaz, M., Delarche, N., Meneveau, N., Ghanem, A., Hagendorff, A., Wilke, A., Hummel, A., Axthelm, C., Kadel, C., Langer, C., Stellbrink, C., Jacobshagen, C., Gross, C. M., Blessing, E. E. B., Minden, H. H., Bogossian, H., Wienbergen, H., Ebelt, H., Dreger, H., Ince, H., Akin, I., Eitel, I., Kreis, I., Appel, K. F., Maier, L., Bergmann, M., Moser, M., Toursarkissian, N., Menck, N., Ritter, O., Bernhardt, P., Nordbeck, P., Stöhring, R., Schwinger, R., Braun-Dullaeus, R. C., Maier, S. K. G., Schellong, S., Steiner, S., Rudolph, T., Dengler, T. J., Geisler, T., Rauch-Kröhnert, U., Jung, W., Jungmair, W., Komócsi, A., Papp, A., Vértes, A., Mohácsi, A., Herczeg, B., Merkely, B., Dézsi, C. A., Kis, E., Lakatos, F., Kerecsen, G., Piros, G. A., Takács, J., Tomcsányi, J., Keltai, K., Kovács, Z., Mathur, A., Baxi, H. A., Narendra, J., Gupta, J., Kumbla, M., Jamwal, N. K., Arora, P., Katz, A., Shotan, A., Schiff, E., Freedberg, N. A., Amir, O., Hussein, O., Kracoff, O. H., Alcalai, R., Adawi, S. Y., Viskin, S., Hayek, T., Hasin, Y., Rozenman, Y., Nam, C. W., Lee, C. W., Choi, D. J., Jeon, D. S., Park, H. W., Son, J. W., Jeong, J. O., Cha, K. S., Oh, S., Rha, S. W., Park, Y. H., On, Y. K., Bazzoni Ruiz, A. E., Valdespino, A. R., Castro Montes, B. E., Ramos Lopez, G. A., Llamas Esperón, G. A., Solache, G., Macías García, J. S., Leiva-Pons, J. L., De Los Rios Ibarra, M. O., Willems, F. F., Beyerbacht, H. P., van de Wal, R., Hysing, J., Lappegard, K. T., Vinge, L. E., Halvorsen, S., Pönitz, V., Chavez Ayala, C. A., Medina Palomino, F. A., Garcia Matheus, J. C., Włodarczak, A., Lubinski, A., Czarnecka, D., Wojciechowski, D., Skonieczny, G., Kasprzak, J. D., Wranicz, J. K., Szachniewicz, J., Kincel, K. K., Zmudka, K., Lesiak, M., Piekarski, M., Wujkowski, M., Lica-Gorzynska, M., Miekus, P., Feusette, P., Bartkowiak, R., Korzeniak, R., Sinkiewicz, W., Musial, W., Krolikowski, Z., Gaspar, A., Pinto, F., Almeida, F., Martinez, J., Brandão, L., Santos, L. M., Mateus, P., Monteiro, P., Pernencar, S., Mornoş, C., Olinic, D. M., Zdrenghea, D. T., Ortan, F. O., Cinteza, M., Popescu, M., Voicu, O., Todea, S. B. F., Babes, V., Vishnevskiy, A. Y., Kuimov, A. D., Duplyakov, D. V., Kosmacheva, E., Pokushalov, E., Gordeev, I. G., Zrazhevskiy, K. N., Sorokin, L. A., Ermoshkina, L. G., Zykov, M. V., Ruda, M. Y., Bulashova, O., Smolenskaya, O. G., Orlikova, O. V., Grishaev, S. L., Shalaev, S. V., Boldueva, S. A., Kuznetsov, V., Makukhin, V., Kostenko, V., Shvarts, Y., Kobalava, Z. D., Selakovic, A., Tosic, B. P., Sakac, D. B., Pavlovic, M., Dekleva, M., Tasic, N. M., Hinic, S., Jozic, T., Potpara, T., Dzupina, A., Pella, D., Majercak, I., Striezova, I., Fedacko, J., Gonsorcik, J., Fecik, J., Selecky, J., Antalik, L., Hranai, M., Gocar, M., Kokles, M., Oriesek, R., Regueiro, A., Ibánez, B., Djurovic, D. P., Gutierrez Ibañes, E., Ridocci-Soriano, F., Diaz Fernandez, J., Artaecheverria Zuazo, J. J., Escudier Villa, J. M., Nuñez Villota, J., Sanmartin Fernandez, M., Chinchurreta Capote, P. A., Muñoz Aguilera, R., Vera Ripoll, T., Mainar Tello, V., Björklund, F., Jensen, J., Andersson, J., Lauermann, J., Hamid, M., Angerås, O., Fischer, T. A., Yagensky, A. V., Goloborodko, B. I., Kyrychenko, I. I., Vakaliuk, I. P., Kovalskyy, I., Rishko, M. V., Sydor, N., Karpenko, O. I., Parkhomenko, O. M., Koval, O. A., Godlevska, O., Zhurba, S., Maslovskyi, V. Y., Netiazhenko, V. Z., Tashchuk, V. K., Shcherbak, V. P., Tseluyko, V. I., Cooke, A., Wrigley, B., Francis, C. M., Barr, C., Gorog, D. A., Lip, G. Y. H., Irving, J., Mills, J., Levy, T., Cheema, A. A., Salacata, A. S., Tenaglia, A. N., Meholick, A. W., Vedere, A. R., Patrello, A. J., Spaedy, A., Martin, A. C., Holland, B. H., Duffy, B. K., Schuler, B., Treasure, C. B., Paraboschi, C., Pickett, C. A., Rowan, C. J., Longnecker, C. R., Hess, C. N., Hinchman, D. A., Schneider, D. J., Murdock, D. K., Baldwin, D. E., Flores, E. A., Sirulnick, E. J., Ahmad, F., Aggarwala, G., Dhar, G., Kichura, G. M., Turitto, G., Sampognaro, G. C., Sharma, G. K., Chandna, H., Truong, H. T. D., Poock, J., Walia, J. S., Zelenka, J. T., Amin, J. K., Foucauld, J., Chambers, J., Abbott, J. D., Strobel, J. S., Dy, J. R., Nour, K. A., Sullenberger, L. E., Younis, L. T., Gonzales, L., Chane, M., Foster, M. T., King, M. Y., Grabarczyk, M. A., Izzo, M. R., Leesar, M. A., Bernabei, M. A., Cavender, M. D., Janik, M. J., Buchbinder, M., Arcarese, M., Yeh, M., Sheth, M. J., Sinno, M. C., Shoukfeh, M. F., Alhaddad, M., Ranadive, N. V., Jaffrani, N. A., Little, N. K., Shammas, N., Assi, N. A., Almousalli, O., Chan, P., Horwitz, P. A., Rozeman, P. A., Singh, P., Aggarwal, R., Gopinathannair, R., Manshadi, R., Korabathina, R., Gilmore, R. M., Feldman, R. B., Schnitzler, R. N., Harrison, R. W., Gandhi, S. N., Graham, S., Krueger, S. K., Jones, S. E., Rowe, S. K., Bazaz, S. B., Haddad, T. M., Povsic, T. J., Badami, U. A., Abernethy, W. B. & Mirza, Z. A., Apr 18 2019, In : New England Journal of Medicine. 380, 16, p. 1509-1524 16 p.

Research output: Contribution to journalArticle

Percutaneous Coronary Intervention
Acute Coronary Syndrome
Atrial Fibrillation
Vitamin K
Aspirin
6 Citations (Scopus)

CONTROL: A randomized phase 2 study of obeticholic acid and atorvastatin on lipoproteins in nonalcoholic steatohepatitis patients

Pockros, P. J., Fuchs, M., Freilich, B., Schiff, E. R., Kohli, A., Lawitz, E. J., Hellstern, P. A., Owens-Grillo, J., Van Biene, C., Shringarpure, R., MacConell, L., Shapiro, D. & Cohen, D. E., Jan 1 2019, (Accepted/In press) In : Liver International.

Research output: Contribution to journalArticle

Lipoproteins
Hydroxymethylglutaryl-CoA Reductase Inhibitors
LDL Cholesterol
Fibrosis
Placebos
555 Citations (Scopus)

Dapagliflozin and cardiovascular outcomes in type 2 diabetes

DECLARE–TIMI 58 Investigators, Jan 24 2019, In : New England Journal of Medicine. 380, 4, p. 347-357 11 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Confidence Intervals
Placebos
Hospitalization
Heart Failure
2018
12 Citations (Scopus)

Deferred treatment with sofosbuvir–velpatasvir–voxilaprevir for patients with chronic hepatitis C virus who were previously treated with an NS5A inhibitor: an open-label substudy of POLARIS-1

Bourlière, M., Gordon, S. C., Schiff, E. R., Tran, T. T., Ravendhran, N., Landis, C. S., Hyland, R. H., Stamm, L. M., Zhang, J., Dvory-Sobol, H., Subramanian, G. M., Brainard, D. M., McHutchison, J. G., Serfaty, L., Thompson, A. J., Sepe, T. E., Curry, M. P., Reddy, K. R. & Manns, M. P., Jan 1 2018, (Accepted/In press) In : The Lancet Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Hepacivirus
Virus Diseases
Therapeutics
Placebos
6 Citations (Scopus)

Differentiation of hepatocyte-like cells from human pluripotent stem cells using small molecules

Asumda, F. Z., Hatzistergos, K. E., Dykxhoorn, D. M., Jakubski, S., Edwards, J., Thomas, E. & Schiff, E. R., May 1 2018, In : Differentiation. 101, p. 16-24 9 p.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Hepatocytes
Endoderm
Periodic Acid
Regenerative Medicine
20 Citations (Scopus)

Hepatitis B Virus Serum DNA and RNA Levels in Nucleos(t)ide Analog-Treated or Untreated Patients During Chronic and Acute Infection

Butler, E. K., Gersch, J., McNamara, A., Luk, K. C., Holzmayer, V., de Medina, M., Schiff, E. R., Kuhns, M. & Cloherty, G. A., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Hepatitis B virus
RNA
DNA
Infection
Serum
3 Citations (Scopus)

Obstacles to successful treatment of hepatitis C in uninsured patients from a minority population

DeBose-Scarlett, A., Balise, R., Kwon, D., Vadaparampil, S., Chen, X., Schiff, E. R., Ayala, G. P. & Thomas, E., Jun 28 2018, In : Journal of Translational Medicine. 16, 1, 178.

Research output: Contribution to journalArticle

Hepatitis C
Viruses
Insurance
Population
Therapeutics
12 Citations (Scopus)

Randomised clinical trial: emricasan versus placebo significantly decreases ALT and caspase activation in subjects with non-alcoholic fatty liver disease

Shiffman, M., Freilich, B., Vuppalanchi, R., Watt, K., Chan, J. L., Spada, A., Hagerty, D. T. & Schiff, E. R., Jan 1 2018, (Accepted/In press) In : Alimentary Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Caspases
Randomized Controlled Trials
Placebos
Transaminases
Keratin-18
10 Citations (Scopus)

Viral eradication is required for sustained improvement of patient-reported outcomes in patients with hepatitis C

Younossi, Z. M., Stepanova, M., Reddy, R., Manns, M. P., Bourliere, M., Gordon, S. C., Schiff, E. R., Tran, T., Younossi, I. & Racila, A., Jan 1 2018, (Accepted/In press) In : Liver International.

Research output: Contribution to journalArticle

Hepatitis C
Placebos
Patient Reported Outcome Measures
Therapeutics
Antiviral Agents
2017
3 Citations (Scopus)
Hepatitis C
Sexually Transmitted Diseases
contagious disease
mortality
minority
1461 Citations (Scopus)

Evolocumab and clinical outcomes in patients with cardiovascular disease

FOURIER Steering Committee and Investigators, May 4 2017, In : New England Journal of Medicine. 376, 18, p. 1713-1722 10 p.

Research output: Contribution to journalArticle

LDL Cholesterol
Cardiovascular Diseases
Placebos
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Stroke
219 Citations (Scopus)

Sofosbuvir, velpatasvir, and voxilaprevir for previously treated HCV infection

POLARIS-4 Investigators, Jun 1 2017, In : New England Journal of Medicine. 376, 22, p. 2134-2146 13 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepacivirus
Genotype
Antiviral Agents
velpatasvir

Supplement-induced liver injury

Schiff, E. R. & Navarro, V. J., Apr 1 2017, In : Gastroenterology and Hepatology. 13, 4, p. 245-247 3 p.

Research output: Contribution to journalComment/debate

Liver
Wounds and Injuries
2016
271 Citations (Scopus)

Daclatasvir with sofosbuvir and ribavirin for hepatitis C virus infection with advanced cirrhosis or post-liver transplantation recurrence

Poordad, F., Schiff, E. R., Vierling, J. M., Landis, C., Fontana, R. J., Yang, R., Mcphee, F., Hughes, E. A., Noviello, S. & Swenson, E. S., 2016, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Ribavirin
Virus Diseases
Hepacivirus
Liver Transplantation
Fibrosis

Early Detection of Steatohepatitis: Less Teeth NASHing and More Research?

Thomas, E. & Schiff, E. R., Jul 1 2016, In : Digestive Diseases and Sciences. 61, 7, p. 1788-1789 2 p.

Research output: Contribution to journalEditorial

Fatty Liver
Liver Cirrhosis
Early Diagnosis
Tooth
Research
121 Citations (Scopus)

Effectiveness of Simeprevir Plus Sofosbuvir, with or Without Ribavirin, in Real-World Patients with HCV Genotype 1 Infection

HCV-TARGET Study Group, Feb 1 2016, In : Gastroenterology. 150, 2, p. 419-429 11 p.

Research output: Contribution to journalArticle

Ribavirin
Hepacivirus
Genotype
Infection
Therapeutics
37 Citations (Scopus)

Efficacy of Sofosbuvir, Velpatasvir, and GS-9857 in Patients With Genotype 1 Hepatitis C Virus Infection in an Open-Label, Phase 2 Trial

Lawitz, E., Reau, N., Hinestrosa, F., Rabinovitz, M., Schiff, E. R., Sheikh, A., Younes, Z., Herring, R., Reddy, K. R., Tran, T., Bennett, M., Nahass, R., Yang, J. C., Lu, S., Dvory-Sobol, H., Stamm, L. M., Brainard, D. M., McHutchison, J. G., Pearlman, B., Shiffman, M. & 3 others, Hawkins, T., Curry, M. & Jacobson, I., Nov 1 2016, In : Gastroenterology. 151, 5, p. 893-901.e1

Research output: Contribution to journalArticle

Virus Diseases
Hepacivirus
Fibrosis
Confidence Intervals
Antiviral Agents
931 Citations (Scopus)

Empagliflozin and progression of kidney disease in type 2 diabetes

EMPA-REG OUTCOME Investigators, Jul 28 2016, In : New England Journal of Medicine. 375, 4, p. 323-334 12 p.

Research output: Contribution to journalArticle

Kidney Diseases
Type 2 Diabetes Mellitus
Kidney
Placebos
Albuminuria
15 Citations (Scopus)

Hepatitis B virus and DNA stimulation trigger a rapid innate immune response through NF-kB

Yoneda, M., Hyun, J., Jakubski, S., Saito, S., Nakajima, A., Schiff, E. R. & Thomas, E., Jul 15 2016, In : Journal of Immunology. 197, 2, p. 630-643 14 p.

Research output: Contribution to journalArticle

NF-kappa B
Innate Immunity
Hepatitis B virus
DNA
Liver

Hepatotoxicity by herbs: a practical review of a neglected disease

Donet, J. A., Sornmayura, K., Gulau, M. & Schiff, E. R., Oct 1 2016, In : Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru. 36, 4, p. 350-353 4 p.

Research output: Contribution to journalReview article

Neglected Diseases
Liver
Acute Liver Failure
Wounds and Injuries
Gastroenterology

Reply

Yoneda, M., Thomas, E. & Schiff, E. R., Mar 1 2016, In : Clinical Gastroenterology and Hepatology. 14, 3, p. 484-485 2 p.

Research output: Contribution to journalArticle

Elasticity Imaging Techniques
Chronic Hepatitis
Liver Cirrhosis
Ultrasonography
Obesity
130 Citations (Scopus)

Simeprevir plus sofosbuvir (12 and 8 weeks) in hepatitis C virus genotype 1-infected patients without cirrhosis: OPTIMIST-1, a phase 3, randomized study

Kwo, P., Gitlin, N., Nahass, R., Bernstein, D., Etzkorn, K., Rojter, S., Schiff, E. R., Davis, M., Ruane, P., Younes, Z., Kalmeijer, R., Sinha, R., Peeters, M., Lenz, O., Fevery, B., De La Rosa, G., Scott, J. & Witek, J., Aug 1 2016, In : Hepatology. 64, 2, p. 370-380 11 p.

Research output: Contribution to journalArticle

Hepacivirus
Fibrosis
Genotype
Therapeutics
Sofosbuvir
2015
30 Citations (Scopus)

Clonal expansion of hepatocytes with a selective advantage occurs during all stages of chronic hepatitis B virus infection

Tu, T., Mason, W. S., Clouston, A. D., Shackel, N. A., McCaughan, G. W., Yeh, M. M., Schiff, E. R., Ruszkiewicz, A. R., Chen, J. W., Harley, H. A. J., Stroeher, U. H. & Jilbert, A. R., Sep 1 2015, In : Journal of Viral Hepatitis. 22, 9, p. 737-753 17 p.

Research output: Contribution to journalArticle

Chronic Hepatitis B
Virus Diseases
Hepatitis B virus
Hepatocytes
Clone Cells
1 Citation (Scopus)

Decreasing liver stiffness following pericardiectomy for constrictive pericarditis

Yoneda, M., Thomas, E., Garcia-Buitrago, M. & Schiff, E. R., Aug 15 2015, In : Internal Medicine. 54, 16, p. 2079-2080 2 p.

Research output: Contribution to journalArticle

Pericardiectomy
Constrictive Pericarditis
Liver
3579 Citations (Scopus)

Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes

EMPA-REG OUTCOME Investigators, Nov 26 2015, In : New England Journal of Medicine. 373, 22, p. 2117-2128 12 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Mortality
Placebos
Cause of Death
Risk Reduction Behavior
1 Citation (Scopus)
Hepatitis C
Chronic Kidney Failure
Safety
Therapeutics
Sofosbuvir
497 Citations (Scopus)

Ledipasvir and Sofosbuvir Plus Ribavirin for Treatment of HCV Infection in Patients with Advanced Liver Disease

Charlton, M., Everson, G. T., Flamm, S. L., Kumar, P., Landis, C., Brown, R. S., Fried, M. W., Terrault, N. A., O'Leary, J. G., Vargas, H. E., Kuo, A., Schiff, E. R., Sulkowski, M. S., Gilroy, R., Watt, K. D., Brown, K., Kwo, P., Pungpapong, S., Korenblat, K. M., Muir, A. J. & 10 others, Teperman, L., Fontana, R. J., Denning, J., Arterburn, S., Dvory-Sobol, H., Brandt-Sarif, T., Pang, P. S., McHutchison, J. G., Reddy, K. R. & Afdhal, N., Sep 1 2015, In : Gastroenterology. 149, 3, p. 649-659 11 p.

Research output: Contribution to journalArticle

Ribavirin
Virus Diseases
Hepacivirus
Liver Diseases
Fibrosis

Roadblocks to accessing direct-acting antiviral agents for treatment of hepatitis C virus infection

Schiff, E. R. & Bernstein, D. E., May 1 2015, In : Gastroenterology and Hepatology. 11, 5, p. 331-333 3 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepacivirus
Antiviral Agents
68 Citations (Scopus)

Safety, efficacy and tolerability of half-dose sofosbuvir plus simeprevir in treatment of Hepatitis C in patients with end stage renal disease

Kalyan Ram, B., Frank, C., Adam, P., Levy, C., Del Pilar Hernandez, M., Jeffers, L. J., Roth, D., Schiff, E. R., O'Brien, C. B. & Martin, P., Sep 1 2015, In : Journal of Hepatology. 63, 3, p. 763-765 3 p., 5707.

Research output: Contribution to journalArticle

Hepatitis C
Combination Drug Therapy
Chronic Kidney Failure
Antiviral Agents
Safety
231 Citations (Scopus)

Sofosbuvir and ribavirin prevent recurrence of hcv infection after liver transplantation: An open-label study

Curry, M. P., Forns, X., Chung, R. T., Terrault, N. A., Brown, R., Fenkel, J. M., Gordon, F., O'Leary, J., Kuo, A., Schiano, T., Everson, G., Schiff, E. R., Befeler, A., Gane, E., Saab, S., McHutchison, J. G., Subramanian, G. M., Symonds, W. T., Denning, J., McNair, L. & 4 others, Arterburn, S., Svarovskaia, E., Moonka, D. & Afdhal, N., Jan 1 2015, In : Gastroenterology. 148, 1, p. 100-107.e1

Research output: Contribution to journalArticle

Ribavirin
Hepacivirus
Liver Transplantation
Recurrence
Transplantation
407 Citations (Scopus)

Sofosbuvir and velpatasvir for HCV in patients with decompensated cirrhosis

Curry, M. P., O'Leary, J. G., Bzowej, N., Muir, A. J., Korenblat, K. M., Fenkel, J. M., Reddy, K. R., Lawitz, E., Flamm, S. L., Schiano, T., Teperman, L., Fontana, R., Schiff, E. R., Fried, M., Doehle, B., An, D., McNally, J., Osinusi, A., Brainard, D. M., McHutchison, J. G. & 2 others, Brown, R. S. & Charlton, M., Dec 31 2015, In : New England Journal of Medicine. 373, 27, p. 2618-2628 11 p.

Research output: Contribution to journalArticle

Hepacivirus
Fibrosis
Ribavirin
Genotype
Confidence Intervals
29 Citations (Scopus)
Elasticity Imaging Techniques
Liver Diseases
Fibrosis
Chronic Disease
Biopsy

Treatment of hepatitis C virus genotype 3 infection

Schiff, E. R. & Poordad, F., Oct 1 2015, In : Gastroenterology and Hepatology. 11, 10, p. 715-717 3 p.

Research output: Contribution to journalArticle

Hepacivirus
Genotype
Infection
20 Citations (Scopus)

Viral hepatitis: Past and future of HBV and HDV

Thomas, E., Yoneda, M. & Schiff, E. R., 2015, In : Cold Spring Harbor perspectives in medicine. 5, 2, a021345.

Research output: Contribution to journalArticle

Viruses
Hepatitis B virus
Hepatitis
Hepatitis Delta Virus
Hepatitis Viruses
2014
16 Citations (Scopus)

Clinical usage of serum ferritin to assess liver fibrosis in patients with non-alcoholic fatty liver disease: Proceed with caution

Yoneda, M., Thomas, E., Sumida, Y., Imajo, K., Eguchi, Y., Hyogo, H., Fujii, H., Ono, M., Kawaguchi, T. & Schiff, E. R., Jan 1 2014, In : Hepatology Research. 44, 14, p. E499-E502

Research output: Contribution to journalArticle

Ferritins
Liver Cirrhosis
Serum
Fibrosis
Sex Characteristics
12 Citations (Scopus)

Effects of statins on the risk of hepatocellular carcinoma

Mansourian, P. G., Yoneda, M., Rao, M. K., Martinez, F. J., Thomas, E. & Schiff, E. R., Jan 1 2014, In : Gastroenterology and Hepatology. 10, 7, p. 417-426 10 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Hepatocellular Carcinoma
Neoplasms
Carcinogenesis
Preexisting Condition Coverage
20 Citations (Scopus)
Ursodeoxycholic Acid
Autoimmune Hepatitis
Biliary Liver Cirrhosis
Hispanic Americans
Cross-Sectional Studies
9 Citations (Scopus)

Infections during peginterferon/ribavirin therapy are associated with the magnitude of decline in absolute lymphocyte count: Results of the IDEAL study

Melia, M. T., Bräu, N., Poordad, F., Lawitz, E. J., Shiffman, M. L., McHutchison, J. G., Muir, A. J., Galler, G. W., Nyberg, L. M., Lee, W. M., Schiff, E. R., Long, J., Noviello, S., Brass, C. A., Pedicone, L. D. & Sulkowski, M. S., 2014, In : Clinical Infectious Diseases. 58, 7, p. 960-969 10 p.

Research output: Contribution to journalArticle

Ribavirin
Lymphocyte Count
Neutrophils
Infection
Interferons
845 Citations (Scopus)

Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis

Kowdley, K. V., Gordon, S. C., Reddy, K. R., Rossaro, L., Bernstein, D. E., Lawitz, E., Shiffman, M. L., Schiff, E. R., Ghalib, R., Ryan, M., Rustgi, V., Chojkier, M., Herring, R., Di Bisceglie, A. M., Pockros, P. J., Subramanian, G. M., An, D., Svarovskaia, E., Hyland, R. H., Pang, P. S. & 5 others, Symonds, W. T., McHutchison, J. G., Muir, A. J., Pound, D. & Fried, M. W., Jan 1 2014, In : New England Journal of Medicine. 370, 20, p. 1879-1888 10 p.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Hepacivirus
Fibrosis
Ribavirin
Confidence Intervals
1027 Citations (Scopus)

Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection

Afdhal, N., Reddy, K. R., Nelson, D. R., Lawitz, E., Gordon, S. C., Schiff, E. R., Nahass, R., Ghalib, R., Gitlin, N., Herring, R., Lalezari, J., Younes, Z. H., Pockros, P. J., Di Bisceglie, A. M., Arora, S., Subramanian, G. M., Zhu, Y., Dvory-Sobol, H., Yang, J. C., Pang, P. S. & 5 others, Symonds, W. T., McHutchison, J. G., Muir, A. J., Sulkowski, M. & Kwo, P., Jan 1 2014, In : New England Journal of Medicine. 370, 16, p. 1483-1493 11 p.

Research output: Contribution to journalArticle

Hepacivirus
Genotype
Ribavirin
Infection
Confidence Intervals
9 Citations (Scopus)

Overall safety profile of boceprevir plus peginterferon alfa-2b and ribavirin in patients with chronic hepatitis C genotype 1: A combined analysis of 3 phase 2/3 clinical trials

Manns, M. P., Mccone, J., Davis, M. N., Rossaro, L., Schiff, E. R., Shiffman, M. L., Bacon, B., Bourliere, M., Sulkowski, M. S., Bruno, S., Balart, L., Bronowicki, J. P., Kwo, P., Poordad, F., Felizarta, F., Reddy, K. R., Helmond, F. A., Sings, H. L., Pedicone, L. D., Burroughs, M. & 3 others, Brass, C. A., Albrecht, J. K. & Vierling, J. M., Jan 1 2014, In : Liver International. 34, 5, p. 707-719 13 p.

Research output: Contribution to journalArticle

Phase III Clinical Trials
Ribavirin
Chronic Hepatitis C
Genotype
Safety
16 Citations (Scopus)

Peginterferon and ribavirin for treatment of recurrent hepatitis C disease in HCV-HIV coinfected liver transplant recipients

Terrault, N., Reddy, K. R., Poordad, F., Curry, M., Schiano, T., Johl, J., Shaikh, O., Dove, L., Shetty, K., Millis, M., Schiff, E. R., Regenstein, F., Barnes, D., Barin, B., Peters, M., Roland, M. & Stock, P., Jan 1 2014, In : American Journal of Transplantation. 14, 5, p. 1129-1135 7 p.

Research output: Contribution to journalArticle

Ribavirin
Hepatitis C
Hepacivirus
HIV
Liver
fibrosis
sound waves
liver
impulses
shear
62 Citations (Scopus)

Staging chronic hepatitis C in seven categories using fibrosis biomarker (FibroTest™) and transient elastography (FibroScan®)

Poynard, T., Vergniol, J., Ngo, Y., Foucher, J., Munteanu, M., Merrouche, W., Colombo, M., Thibault, V., Schiff, E. R., Brass, C. A., Albrecht, J. K., Rudler, M., Deckmyn, O., Lebray, P., Thabut, D., Ratziu, V. & De Ledinghen, V., Jan 1 2014, In : Journal of Hepatology. 60, 4, p. 706-714 9 p.

Research output: Contribution to journalArticle

Elasticity Imaging Techniques
Chronic Hepatitis C
Fibrosis
Biomarkers
Liver Neoplasms
10 Citations (Scopus)

The influence of menopause on the development of hepatic fibrosis in nonobese women with nonalcoholic fatty liver disease

Yoneda, M., Thomas, E., Sumida, Y., Eguchi, Y. & Schiff, E. R., Nov 1 2014, In : Hepatology (Baltimore, Md.). 60, 5

Research output: Contribution to journalArticle

Severity of Illness Index
Sex Factors
Fatty Liver
Menopause
Liver Cirrhosis
2013
12 Citations (Scopus)

An update on the hepatitis E virus.

Sclair, S. N. & Schiff, E. R., Feb 1 2013, In : Current Gastroenterology Reports. 15, 2

Research output: Contribution to journalArticle

Hepatitis E
Hepatitis E virus
Swine Diseases
Endemic Diseases
Zoonoses
39 Citations (Scopus)

Cost-effectiveness of screening for chronic hepatitis C infection in the United States

Eckman, M. H., Talal, A. H., Gordon, S. C., Schiff, E. R. & Sherman, K. E., May 15 2013, In : Clinical Infectious Diseases. 56, 10, p. 1382-1393 12 p.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Hepacivirus
Cost-Benefit Analysis
Quality-Adjusted Life Years
Infection
28 Citations (Scopus)

Drug-induced cholestasis

Bhamidimarri, K. R. & Schiff, E. R., Nov 1 2013, In : Clinics in Liver Disease. 17, 4, p. 519-531 13 p.

Research output: Contribution to journalArticle

Cholestasis
Pharmaceutical Preparations
Complementary Therapies
Wounds and Injuries
Chemical and Drug Induced Liver Injury

Erratum: FibroTest is an independent predictor of virologic response in chronic hepatitis C patients retreated with pegylated interferon alfa-2b and ribavirin in the EPIC3 program (Journal of Hepatology (2011) 54 (227-235))

Poynard, T., Munteanu, M., Colombo, M., Bruix, J., Schiff, E. R., Terg, R., Flamm, S., Moreno-Otero, R., Carrilho, F., Schmidt, W., Berg, T., McGarrity, T., Heathcote, E. J., Gonçales, F., Diago, M., Craxi, A., Silva, M., Boparai, N., Griffel, L., Burroughs, M. & 2 others, Brass, C. & Albrecht, J., Oct 1 2013, In : Journal of Hepatology. 59, 4

Research output: Contribution to journalArticle

Ribavirin
Chronic Hepatitis C
Gastroenterology
peginterferon alfa-2b
2 Citations (Scopus)

High frequency of genotype D and spontaneous hepatitis B virus genomic mutations among haitians in a multiethnic North American population

Couto, C. A., Levy, C., Morris, C. J., Hill, M., De Medina, M., Sanborn, M. R., Cloherty, G. A., Schiff, E. R. & Martin, P., Jan 1 2013, In : Journal of Clinical Gastroenterology. 47, 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Genotype
Mutation
Population
Genetic Promoter Regions