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  • Camillo Ricordi
Article

From cellular therapies to tissue reprogramming and regenerative strategies in the treatment of diabetes

Ricordi, C., Inverardi, L. & Domínguez-Bendala, J., Nov 1 2012, In : Regenerative Medicine. 7, 6 SUPPL., p. 41-48 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Fully automated islet cell counter (ICC) for the assessment of islet mass, purity, and size distribution by digital image analysis

Buchwald, P., Bernal, A., Echeverri, F., Tamayo-Garcia, A., Linetsky, E. & Ricordi, C., 2016, In : Cell Transplantation. 25, 10, p. 1747-1761 15 p.

Research output: Contribution to journalArticle

7 Scopus citations

G-CSF and exenatide might be associated with increased long-term survival of allogeneic pancreatic islet grafts

Zoso, A., Serafini, P., Lanzoni, G., Peixoto, E., Messinger, S., Mantero, A., Padilla-Téllez, N. D., Baidal, D. A., Alejandro, R., Ricordi, C. & Inverardi, L., Jun 2016, In : PloS one. 11, 6, e0157245.

Research output: Contribution to journalArticle

3 Scopus citations

Generation of Glucose-Responsive, Insulin-Producing Cells from Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells

Prabakar, K. R., Domínguez-Bendala, J., Damaris Molano, R., Pileggi, A., Villate, S., Ricordi, C. & Inverardi, L., Sep 3 2012, In : Cell Transplantation. 21, 6, p. 1321-1339 19 p.

Research output: Contribution to journalArticle

48 Scopus citations

High-resolution, noninvasive longitudinal live imaging of immune responses

Abdulreda, M. H., Faleo, G., Molano, R. D., Lopez-Cabezas, M., Molina, J., Tan, Y., Ron Echeverria, O. A., Zahr-Akrawi, E., Rodriguez-Diaz, R., Edlund, P. K., Leibiger, I., Bayer, A. L., Perez, V., Ricordi, C., Caicedo, A., Pileggi, A. & Berggren, P. O., Aug 2 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 31, p. 12863-12868 6 p.

Research output: Contribution to journalArticle

53 Scopus citations

Immunoisolation of murine islet allografts in vascularized sites through conformal coating with polyethylene glycol

Manzoli, V., Villa, C., Bayer, A. L., Morales, L. C., Molano, R., Torrente, Y., Ricordi, C., Hubbell, J. A. & Tomei, A. A., Jan 1 2017, (Accepted/In press) In : American Journal of Transplantation.

Research output: Contribution to journalArticle

20 Scopus citations

Impact of statins on the coagulation status of type 2 diabetes patients evaluated by a novel thrombin-generation assay

Ferroni, P., Della-Morte, D., Pileggi, A., Valente, M. G., Martini, F., La Farina, F., Palmirotta, R., Meneghini, L. F., Rundek, T., Ricordi, C. & Guadagni, F., Aug 1 2012, In : Cardiovascular Drugs and Therapy. 26, 4, p. 301-309 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Improved human islet preparations using glucocorticoid and exendin-4

Miki, A., Ricordi, C., Yamamoto, T., Sakuma, Y., Misawa, R., Mita, A., Inverardi, L., Alejandro, R. & Ichii, H., Nov 10 2014, In : Pancreas. 43, 8, p. 1317-1322 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: A randomized controlled trial

Tan, J., Wu, W., Xu, X., Liao, L., Zheng, F., Messinger, S., Sun, X., Chen, J., Yang, S., Cai, J., Gao, X., Pileggi, A. & Ricordi, C., Mar 21 2012, In : JAMA - Journal of the American Medical Association. 307, 11, p. 1169-1177 9 p.

Research output: Contribution to journalArticle

340 Scopus citations

Inflammasome Proteins in Serum and Serum-Derived Extracellular Vesicles as Biomarkers of Stroke

Kerr, N., García-Contreras, M., Abbassi, S., Mejias, N. H., Desousa, B. R., Ricordi, C., Dietrich, W. D., Keane, R. W. & de Rivero Vaccari, J. P., Sep 4 2018, In : Frontiers in Molecular Neuroscience. 11, 309.

Research output: Contribution to journalArticle

14 Scopus citations

Influence of in vitro and in vivo oxygen modulation on β cell differentiation from human embryonic stem cells

Cechin, S., Álvarez-Cubela, S., Giraldo, J. A., Molano, R. D., Villate, S., Ricordi, C., Pileggi, A., Inverardi, L., Fraker, C. A. & Domínguez-Bendala, J., 2014, In : Stem Cells Translational Medicine. 3, 3, p. 277-289 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

Innervation patterns of autonomic axons in the human endocrine pancreas

Rodriguez-Diaz, R., Abdulreda, M. H., Formoso, A. L., Gans, I., Ricordi, C., Berggren, P-O. Y. & Caicedo, A., Jul 6 2011, In : Cell Metabolism. 14, 1, p. 45-54 10 p.

Research output: Contribution to journalArticle

172 Scopus citations

Insulin-mimetic effects of short-term rapamycin in type 1 diabetic patients prior to islet transplantation

Benedini, S., Ermetici, F., Briganti, S., Codella, R., Terruzzi, I., Maffi, P., Caldara, R., Secchi, A., Nano, R., Piemonti, L., Alejandro, R., Ricordi, C. & Luzi, L., Apr 13 2018, (Accepted/In press) In : Acta Diabetologica. p. 1-8 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Intracardial embryonic delivery of developmental modifiers in utero

Domínguez-Bendala, J., Álvarez-Cubela, S., Nieto, M., Vargas, N., Espino-Grosso, P., Sacher, V. Y., Pileggi, A., García, E., Ricordi, C., Inverardi, L. & Pastori, R. L., Sep 1 2012, In : Cold Spring Harbor Protocols. 7, 9, p. 962-968 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

In vivo induction of myeloid suppressor cells and CD4 +foxp3 + T regulatory cells prolongs skin allograft survival in mice

Adeegbe, D., Serafini, P., Bronte, V., Zoso, A., Ricordi, C. & Inverardi, L., Aug 22 2011, In : Cell transplantation. 20, 6, p. 941-954 14 p.

Research output: Contribution to journalArticle

47 Scopus citations

Islet-derived EATP fuels autoreactive CD8 + T cells and facilitates the onset of type 1 diabetes

Tezza, S., Nasr, M. B., D'Addio, F., Vergani, A., Usuelli, V., Falzoni, S., Bassi, R., Dellepiane, S., Fotino, C., Rossi, C., Maestroni, A., Solini, A., Corradi, D., Giani, E., Mameli, C., Bertuzzi, F., Pezzolesi, M. G., Wasserfall, C. H., Atkinson, M. A., Füchtbauer, E. M. & 7 others, Ricordi, C., Folli, F., Virgilio, F. D., Pileggi, A., Dhe-Paganon, S., Zuccotti, G. V. & Fiorina, P., Oct 1 2018, In : Diabetes. 67, 10, p. 2038-2053 16 p.

Research output: Contribution to journalArticle

4 Scopus citations

Islet-Like Structures Generated In Vitro from Adult Human Liver Stem Cells Revert Hyperglycemia in Diabetic SCID Mice

Navarro-Tableros, V., Gai, C., Gomez, Y., Giunti, S., Pasquino, C., Deregibus, M. C., Tapparo, M., Pitino, A., Tetta, C., Brizzi, M. F., Ricordi, C. & Camussi, G., Jan 1 2018, (Accepted/In press) In : Stem Cell Reviews and Reports.

Research output: Contribution to journalArticle

5 Scopus citations

Islet product characteristics and factors related to successful human islet transplantation from the collaborative islet transplant registry (CITR) 1999-2010

Balamurugan, A. N., Naziruddin, B., Lockridge, A., Tiwari, M., Loganathan, G., Takita, M., Matsumoto, S., Papas, K., Trieger, M., Rainis, H., Kin, T., Kay, T. W., Wease, S., Messinger, S., Ricordi, C., Alejandro, R., Markmann, J., Kerr-Conti, J., Rickels, M. R., Liu, C. & 9 others, Zhang, X., Witkowski, P., Posselt, A., Maffi, P., Secchi, A., Berney, T., O'Connell, P. J., Hering, B. J. & Barton, F. B., Nov 1 2014, In : American Journal of Transplantation. 14, 11, p. 2595-2606 12 p.

Research output: Contribution to journalArticle

76 Scopus citations

Liver fat accumulation after islet transplantation and graft survival

Leitão, C. B., Peixoto, E. M. L., Westphalen, A. C., Mireles-Zavala, L. G., Lauriola, V., Bernetti, K., Corrales, A., Ricordi, C. & Alejandro, R., 2014, In : Cell transplantation. 23, 10, p. 1221-1227 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Long-term culture of human pancreatic slices as a model to study real-time islet regeneration

Qadir, M. M. F., Álvarez-Cubela, S., Weitz, J., Panzer, J. K., Klein, D., Moreno-Hernández, Y., Cechin, S., Tamayo, A., Almaca, J., Hiller, H., Beery, M., Kusmartseva, I., Atkinson, M., Speier, S., Ricordi, C., Pugliese, A., Caicedo-Vierkant, D. A., Fraker, C., Pastori, R. & Dominguez-Bendala, J., Dec 1 2020, In : Nature communications. 11, 1, 3265.

Research output: Contribution to journalArticle

Open Access

Long-term heart transplant survival by targeting the ionotropic purinergic receptor P2X7

Vergani, A., Tezza, S., D'Addio, F., Fotino, C., Liu, K., Niewczas, M., Bassi, R., Molano, R. D., Kleffel, S., Petrelli, A., Soleti, A., Ammirati, E., Frigerio, M., Visner, G., Grassi, F., Ferrero, M. E., Corradi, D., Abdi, R., Ricordi, C., Sayegh, M. H. & 2 others, Pileggi, A. & Fiorina, P., Jan 29 2013, In : Circulation. 127, 4, p. 463-475 13 p.

Research output: Contribution to journalArticle

68 Scopus citations

Lower prediagnostic serum 25-hydroxyvitamin D concentration is associated with higher risk of insulin-requiring diabetes: A nested case-control study

Gorham, E. D., Garland, C. F., Burgi, A. A., Mohr, S. B., Zeng, K., Hofflich, H., Kim, J. J. & Ricordi, C., Dec 1 2012, In : Diabetologia. 55, 12, p. 3224-3227 4 p.

Research output: Contribution to journalArticle

34 Scopus citations

Macroporous three-dimensional PDMS scaffolds for Extrahepatic Islet Transplantation

Pedraza, E., Brady, A. C., Fraker, C. A., Molano, R. D., Sukert, S., Berman, D. M., Kenyon, N. S., Pileggi, A., Ricordi, C. & Stabler, C. L., 2013, In : Cell transplantation. 22, 7, p. 1123-1125 3 p.

Research output: Contribution to journalArticle

56 Scopus citations

Mesenchymal stem cells ameliorate β cell dysfunction of human type 2 diabetic islets by reversing β cell dedifferentiation

Wang, L., Liu, T., Liang, R., Wang, G., Liu, Y., Zou, J., Liu, N., Zhang, B., Liu, Y., Ding, X., Cai, X., Wang, Z., Xu, X., Ricordi, C., Wang, S. & Shen, Z., Jan 2020, In : EBioMedicine. 51, 102615.

Research output: Contribution to journalArticle

Open Access

Metabolomic changes in human adipose tissue derived products following non-enzymatic microfacturing

Garcia-Contreras, M., Messaggio, F., Mendez, A. J. & Ricordi, C., Jan 1 2018, In : European Review for Medical and Pharmacological Sciences. 22, 10, p. 3249-3260 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Metabolomics Study of the Effects of Inflammation, Hypoxia, and High Glucose on Isolated Human Pancreatic Islets

Garcia-Contreras, M., Tamayo-Garcia, A., Pappan, K. L., Michelotti, G. A., Stabler, C., Ricordi, C. & Buchwald, P., Jun 2 2017, In : Journal of Proteome Research. 16, 6, p. 2294-2306 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Metformin restrains pancreatic duodenal homeobox-1 (PDX-1) function by inhibiting ERK signaling in pancreatic ductal adenocarcinoma

Zhou, G., Yu, J., Wang, A., Liu, S. H., Sinnett-Smith, J., Wu, J., Sanchez, R., Nemunaitis, J., Ricordi, C., Rozengurt, E. & Brunicardi, F. C., Jan 1 2016, In : Current Molecular Medicine. 16, 1, p. 83-90 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Microencapsulated adult porcine islets transplanted intraperitoneally in streptozotocin-diabetic non-human primates

Safley, S. A., Kenyon, N. S., Berman-Weinberg, D., Barber, G. F., Willman, M., Duncanson, S., Iwakoshi, N., Holdcraft, R., Gazda, L., Thompson, P., Badell, I. R., Sambanis, A., Ricordi, C. & Weber, C. J., Jan 1 2018, (Accepted/In press) In : Xenotransplantation.

Research output: Contribution to journalArticle

17 Scopus citations

MicroRNA Expression in Alpha and Beta Cells of Human Pancreatic Islets

Klein, D., Misawa, R., Bravo-Egana, V., Vargas, N., Rosero, S., Piroso, J., Ichii, H., Umland, O., Zhijie, J., Tsinoremas, N., Ricordi, C., Inverardi, L., Domínguez-Bendala, J. & Pastori, R. L., Jan 29 2013, In : PloS one. 8, 1, e55064.

Research output: Contribution to journalArticle

76 Scopus citations

MicroRNAs in islet immunobiology and transplantation

Pileggi, A., Klein, D., Fotino, C., Bravo-Egaña, V., Rosero, S., Doni, M., Podetta, M., Ricordi, C., Molano, R. D. & Pastori, R. L., Dec 1 2013, In : Immunologic Research. 57, 1-3, p. 185-196 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Moderate intensity training impact on the inflammatory status and glycemic profiles in NOD mice

Codella, R., Lanzoni, G., Zoso, A., Caumo, A., Montesano, A., Terruzzi, I. M., Ricordi, C., Luzi, L. & Inverardi, L., 2015, In : Journal of Diabetes Research. 2015, 737586.

Research output: Contribution to journalArticle

10 Scopus citations

Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets

Cardinale, V., Wang, Y., Carpino, G., Cui, C. B., Gatto, M., Rossi, M., Bartolomeo Berloco, P., Cantafora, A., Wauthier, E., Furth, M. E., Inverardi, L., Dominguez-Bendala, J., Ricordi, C., Gerber, D., Gaudio, E., Alvaro, D. & Reid, L. M., Dec 1 2011, In : Hepatology. 54, 6, p. 2159-2172 14 p.

Research output: Contribution to journalArticle

205 Scopus citations

National institutes of health-sponsored clinical islet transplantation consortium phase 3 trial: Manufacture of a complex cellular product at eight processing facilities

Ricordi, C., Goldstein, J. S., Balamurugan, A. N., Szot, G. L., Kin, T., Liu, C., Czarniecki, C. W., Barbaro, B., Bridges, N. D., Cano, J., Clarke, W. R., Eggerman, T. L., Hunsicker, L. G., Kaufman, D. B., Khan, A., Lafontant, D. E., Linetsky, E., Luo, X., Markmann, J. F., Naji, A. & 14 others, Korsgren, O., Oberholzer, J., Turgeon, N. A., Brandhorst, D., Friberg, A. S., Lei, J., Wang, L. J., Wilhelm, J. J., Willits, J., Zhang, X., Hering, B. J., Posselt, A. M., Stock, P. G. & Shapiro, A. M. J., Nov 2016, In : Diabetes. 65, 11, p. 3418-3428 11 p.

Research output: Contribution to journalArticle

54 Scopus citations

Noninvasive in vivo model demonstrating the effects of autonomic innervation on pancreatic islet function

Rodriguez-Diaz, R., Speier, S., Molano, R. D., Formoso, A., Gans, I., Abdulreda, M. H., Cabrera, O., Molina, J., Fachado, A., Ricordi, C., Leibiger, I., Pileggi, A., Berggren, P. O. & Caicedo, A., Dec 26 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 52, p. 21456-21461 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

Omega-3 PUFAs and vitamin D co-supplementation as a safe-effective therapeutic approach for core symptoms of autism spectrum disorder: case report and literature review

Infante, M., Sears, B., Rizzo, A. M., Mariani Cerati, D., Caprio, M., Ricordi, C. & Fabbri, A., Jan 1 2018, (Accepted/In press) In : Nutritional Neuroscience.

Research output: Contribution to journalArticle

7 Scopus citations
27 Scopus citations

Osteocalcin effect on human β-cells mass and function

Sabek, O. M., Nishimoto, S. K., Fraga, D., Tejpal, N., Ricordi, C. & Gaber, A. O., Sep 1 2015, In : Endocrinology. 156, 9, p. 3137-3146 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

P2RY1/ALK3-Expressing Cells within the Adult Human Exocrine Pancreas Are BMP-7 Expandable and Exhibit Progenitor-like Characteristics

Qadir, M. M. F., Álvarez-Cubela, S., Klein, D., Lanzoni, G., García-Santana, C., Montalvo, A., Pláceres-Uray, F., Mazza, E. M. C., Ricordi, C., Inverardi, L. A., Pastori, R. L. & Domínguez-Bendala, J., Feb 27 2018, In : Cell Reports. 22, 9, p. 2408-2420 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point

Rodriguez-Diaz, R., Molano, R., Weitz, J. R., Abdulreda, M. H., Berman, D. M., Leibiger, B., Leibiger, I. B., Kenyon, N. S., Ricordi, C., Pileggi, A., Caicedo, A. & Berggren, P-O. Y., Mar 6 2018, In : Cell Metabolism. 27, 3, p. 549-558.e4

Research output: Contribution to journalArticle

36 Scopus citations

Phase 3 trial of transplantation of human islets in type 1 diabetes complicated by severe hypoglycemia

Hering, B. J., Clarke, W. R., Bridges, N. D., Eggerman, T. L., Alejandro, R., Bellin, M. D., Chaloner, K., Czarniecki, C. W., Goldstein, J. S., Hunsicker, L. G., Kaufman, D. B., Korsgren, O., Larsen, C. P., Luo, X., Markmann, J. F., Naji, A., Oberholzer, J., Posselt, A. M., Rickels, M. R., Ricordi, C. & 5 others, Robien, M. A., Senior, P. A., James Shapiro, A. M., Stock, P. G. & Turgeon, N. A., Jul 1 2016, In : Diabetes care. 39, 7, p. 1230-1240 11 p.

Research output: Contribution to journalArticle

195 Scopus citations

Plasma-derived exosome characterization reveals a distinct microRNA signature in long duration Type 1 diabetes

Garcia-Contreras, M., Shah, S. H., Tamayo, A., Robbins, P. D., Golberg, R. B., Mendez, A. J. & Ricordi, C., Dec 1 2017, In : Scientific Reports. 7, 1, 5998.

Research output: Contribution to journalArticle

36 Scopus citations

Present and future cell therapies for pancreatic beta cell replenishment

Domínguez-Bendala, J. & Ricordi, C., Dec 1 2012, In : World Journal of Gastroenterology. 18, 47, p. 6876-6884 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
177 Scopus citations

Prevention of autoimmune diabetes and induction of β-cell proliferation in NOD mice by hyperbaric oxygen therapy

Faleo, G., Fotino, C., Bocca, N., Molano, R. D., Zahr-Akrawi, E., Molina, J., Villate, S., Umland, O., Skyler, J. S., Bayer, A. L., Ricordi, C. & Pileggi, A., Jul 1 2012, In : Diabetes. 61, 7, p. 1769-1778 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Proangiogenic hydrogels within macroporous scaffolds enhance islet engraftment in an extrahepatic site

Brady, A. C., Martino, M. M., Pedraza, E., Sukert, S., Pileggi, A., Ricordi, C., Hubbell, J. A. & Stabler, C. L., Dec 1 2013, In : Tissue Engineering - Part A. 19, 23-24, p. 2544-2552 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Quantification of the islet product: Presentation of a standardized current good manufacturing practices compliant system with minimal variability

Friberg, A. S., Brandhorst, H., Buchwald, P., Goto, M., Ricordi, C., Brandhorst, D. & Korsgren, O., Mar 27 2011, In : Transplantation. 91, 6, p. 677-683 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Quantitative in situ analysis of FoxP3 + T regulatory cells on transplant tissue using laser scanning cytometry

Takahashi, H., Ruiz, P., Ricordi, C., Delacruz, V., Miki, A., Mita, A., Misawa, R., Barker, S., Burke, G. W., Tzakis, A. G. & Ichii, H., 2012, In : Cell transplantation. 21, 1, p. 113-125 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Regional Differences in Islet Distribution in the Human Pancreas - Preferential Beta-Cell Loss in the Head Region in Patients with Type 2 Diabetes

Wang, X., Misawa, R., Zielinski, M. C., Cowen, P., Jo, J., Periwal, V., Ricordi, C., Khan, A., Szust, J., Shen, J., Millis, J. M., Witkowski, P. & Hara, M., Jun 24 2013, In : PloS one. 8, 6, e67454.

Research output: Contribution to journalArticle

77 Scopus citations

Remote Processing of Pancreas can Restore Normal Glucose Homeostasis in Autologous Islet Transplantation after Traumatic Whipple Pancreatectomy: Technical Considerations

Khan, A., Jindal, R. M., Shriver, C., Guy, S. R., Vertrees, A. E., Wang, X., Xu, X., Szust, J. & Ricordi, C., Sep 3 2012, In : Cell Transplantation. 21, 6, p. 1261-1267 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Report from IPITA-TTS opinion leaders meeting on the future of β-cell replacement

Bartlett, S. T., Markmann, J. F., Johnson, P., Korsgren, O., Hering, B. J., Scharp, D., Kay, T. W. H., Bromberg, J., Odorico, J. S., Weir, G. C., Bridges, N., Kandaswamy, R., Stock, P., Friend, P., Gotoh, M., Cooper, D. K. C., Park, C. G., O'Connell, P., Stabler, C., Matsumoto, S. & 14 others, Ludwig, B., Choudhary, P., Kovatchev, B., Rickels, M. R., Sykes, M., Wood, K., Kraemer, K., Hwa, A., Stanley, E., Ricordi, C., Zimmerman, M., Greenstein, J., Montanya, E. & Otonkoski, T., 2016, In : Transplantation. 100, p. S1-S44

Research output: Contribution to journalArticle

35 Scopus citations