Find Research Outputs — University of Miami's Research Profiles

2019

Pre-clinical evaluation of Minnelide as a therapy for acute myeloid leukemia

Giri, B., Gupta, V. K., Yaffe, B., Modi, S., Roy, P., Sethi, V., Lavania, S. P., Vickers, S. M., Dudeja, V., Banerjee, S., Watts, J. & Saluja, A., May 20 2019, In: Journal of translational medicine. 17, 1, 163.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

2020

Know Thy Enemy—Understanding the Role of Inflammation in Severe Acute Pancreatitis

Iyer, S., Bawa, E. P., Tarique, M. & Dudeja, V., Jan 2020, In: Gastroenterology. 158, 1, p. 46-48 3 p.

Research output: Contribution to journal › Editorial › peer-review

2 Scopus citations

2017

Modulation of post-translational modifications in β-catenin and LRP6 inhibits Wnt signaling pathway in pancreatic cancer

Garg, B., Giri, B., Majumder, K., Dudeja, V., Banerjee, S. & Saluja, A., Mar 1 2017, In: Cancer Letters. 388, p. 64-72 9 p.

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

2014

Triptolide sensitizes pancreatic cancer cells to TRAIL-induced activation of the Death Receptor pathway

Chen, Z., Sangwan, V., Banerjee, S., Chugh, R., Dudeja, V., Vickers, S. M. & Saluja, A. K., 2014, In: Cancer letters. 348, 1-2, p. 156-166 11 p.

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

2012

Is there a Role for Surgery with Adequate Nodal Evaluation Alone in Gastric Adenocarcinoma?

Dudeja, V., Habermann, E. B., Abraham, A., Zhong, W., Parsons, H. M., Tseng, J. F. & Al-Refaie, W. B., Feb 2012, In: Journal of Gastrointestinal Surgery. 16, 2, p. 238-247 10 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

2020

Modulation of macrophage polarity for treatment of acute pancreatitis: Are we there yet?

Sahay, P., P. Bava, E., Iyer, S. & Dudeja, V., Oct 2020, In: EBioMedicine. 60, 103002.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

2019

Radiotherapy as an Adjunct to Surgery for Pancreatic Cancer: Where Are We After More Than 30 Years of Research and Trials?

Ferrantella, A., Dudeja, V. & Are, C., Dec 1 2019, In: Annals of Surgical Oncology. 26, 13, p. 4166-4167 2 p.

Research output: Contribution to journal › Editorial › peer-review

Open Access

2011

Guideline recommended gastric cancer care in the elderly: Insights into the applicability of cancer trials to real world

Dudeja, V., Habermann, E. B., Zhong, W., Tuttle, T. M., Vickers, S. M., Jensen, E. H. & Al-Refaie, W. B., Jan 2011, In: Annals of Surgical Oncology. 18, 1, p. 26-33 8 p.

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

2017

Minnelide Inhibits Androgen Dependent, Castration Resistant Prostate Cancer Growth by Decreasing Expression of Androgen Receptor Full Length and Splice Variants

Isharwal, S., Modi, S., Arora, N., Uhlrich, C., Giri, B., Barlass, U., Soubra, A., Chugh, R., Dehm, S. M., Dudeja, V., Saluja, A., Banerjee, S. & Konety, B., May 1 2017, In: Prostate. 77, 6, p. 584-596 13 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

2015

Premalignant cystic neoplasms of the pancreas

Dudeja, V. & Allen, P. J., Jan 1 2015, In: Seminars in Oncology. 42, 1, p. 70-85 16 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

2017

“Heat shock protein 70 in pancreatic diseases: Friend or foe”

Giri, B., Sethi, V., Modi, S., Garg, B., Banerjee, S., Saluja, A. & Dudeja, V., Jul 1 2017, In: Journal of surgical oncology. 116, 1, p. 114-122 9 p.

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

The Impact of Surgeon Volume on Outcomes After Pancreaticoduodenectomy: a Meta-analysis

Macedo, F. I. B., Jayanthi, P., Mowzoon, M., Yakoub, D., Dudeja, V. & Merchant, N., Oct 1 2017, In: Journal of Gastrointestinal Surgery. 21, 10, p. 1723-1731 9 p.

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

2012

A preclinical evaluation of minnelide as a therapeutic agent against pancreatic cancer

Chugh, R., Sangwan, V., Patil, S. P., Dudeja, V., Dawra, R. K., Banerjee, S., Schumacher, R. J., Blazar, B. R., Georg, G. I., Vickers, S. M. & Saluja, A. K., Oct 17 2012, In: Science Translational Medicine. 4, 156, 156ra139.

Research output: Contribution to journal › Article › peer-review

171 Scopus citations

2011

Intra-acinar trypsinogen activation mediates early stages of pancreatic injury but not inflammation in mice with acute pancreatitis

Dawra, R., Sah, R. P., Dudeja, V., Rishi, L., Talukdar, R., Garg, P. & Saluja, A. K., Dec 2011, In: Gastroenterology. 141, 6, p. 2210-2217.e2

Research output: Contribution to journal › Article › peer-review

140 Scopus citations

2016

Microenvironment mediated alterations to metabolic pathways confer increased chemo-resistance in CD133⁺ tumor initiating cells

Nomura, A., Dauer, P., Gupta, V., McGinn, O., Arora, N., Majumdar, K., Uhlrich, C., Dalluge, J., Dudeja, V., Saluja, A. & Banerjee, S., 2016, In: Oncotarget. 7, 35, p. 56324-56337 14 p.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Minnelide Overcomes Oxaliplatin Resistance by Downregulating the DNA Repair Pathway in Pancreatic Cancer

Modi, S., Kir, D., Giri, B., Majumder, K., Arora, N., Dudeja, V., Banerjee, S. & Saluja, A. K., Jan 1 2016, In: Journal of Gastrointestinal Surgery. 20, 1, p. 13-24 12 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

2017

Predicting Residual Disease in Incidental Gallbladder Cancer: Risk Stratification for Modified Treatment Strategies

Creasy, J. M., Goldman, D. A., Gonen, M., Dudeja, V., Askan, G., Basturk, O., Balachandran, V. P., Allen, P. J., DeMatteo, R. P., D’Angelica, M. I., Jarnagin, W. R. & Peter Kingham, T., Aug 1 2017, In: Journal of Gastrointestinal Surgery. 21, 8, p. 1254-1261 8 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

2011

Molecular targeted approaches for treatment of pancreatic cancer

Huang, Z. Q., Saluja, A. K., Dudeja, V., Vickers, S. M. & Buchsbaum, D. J., Jul 2011, In: Current pharmaceutical design. 17, 21, p. 2221-2238 18 p.

Research output: Contribution to journal › Review article › peer-review

17 Scopus citations

2019

O-GlcNAc modification of Sox2 regulates self-renewal in pancreatic cancer by promoting its stability

Sharma, N. S., Gupta, V. K., Dauer, P., Kesh, K., Hadad, R., Giri, B., Chandra, A., Dudeja, V., Slawson, C., Banerjee, S., Vickers, S. M., Saluja, A. & Banerjee, S., 2019, In: Theranostics. 9, 12, p. 3410-3424 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2018

Gut Microbiota Promotes Tumor Growth in Mice by Modulating Immune Response

Sethi, V., Kurtom, S., Tarique, M., Lavania, S., Malchiodi, Z., Hellmund, L., Zhang, L., Sharma, U., Giri, B., Garg, B., Ferrantella, A., Vickers, S. M., Banerjee, S., Dawra, R., Roy, S., Ramakrishnan, S., Saluja, A. & Dudeja, V., Jul 2018, In: Gastroenterology. 155, 1, p. 33-37.e6

Research output: Contribution to journal › Article › peer-review

62 Scopus citations

Metastasis and chemoresistance in CD133 expressing pancreatic cancer cells are dependent on their lipid raft integrity

Gupta, V. K., Sharma, N. S., Kesh, K., Dauer, P., Nomura, A., Giri, B., Dudeja, V., Banerjee, S., Bhattacharya, S. K., Saluja, A. & Banerjee, S., Dec 28 2018, In: Cancer Letters. 439, p. 101-112 12 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

2020

Impact of the coronavirus disease 2019 pandemic on surgical research and lessons for the future

Keswani, S. G., Parikh, U. M., Gosain, A., Ghaferi, A. A., Thomas, J. S., Dudeja, V., Kim, E. S., Zuckerbraun, B. S. & Goldstein, A. M., 2020, (Accepted/In press) In: Surgery (United States).

Research output: Contribution to journal › Article › peer-review

Open Access

2012

Do Hospital attributes predict guideline-recommended gastric cancer care in the United States?

Dudeja, V., Gay, G., Habermann, E. B., Tuttle, T. M., Tseng, J. F., Feig, B. W. & Al-Refaie, W. B., Feb 2012, In: Annals of Surgical Oncology. 19, 2, p. 365-372 8 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

2019

ER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining “stemness”

Dauer, P., Sharma, N. S., Gupta, V. K., Durden, B., Hadad, R., Banerjee, S., Dudeja, V., Saluja, A. & Banerjee, S., Feb 1 2019, In: Cell Death and Disease. 10, 2, 132.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

2020

Minimally Invasive Surgery is Associated with an Increased Risk of Postoperative Venous Thromboembolism After Distal Pancreatectomy

Willobee, B. A., Dosch, A. R., Allen, C. J., Macedo, F. I., Bartholomew, T. S., Picado, O., Gaidarski, A. A., Dudeja, V., Yakoub, D. & Merchant, N. B., Jul 1 2020, In: Annals of Surgical Oncology. 27, 7, p. 2498-2505 8 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

2018

Morphine worsens the severity and prevents pancreatic regeneration in mouse models of acute pancreatitis

Barlass, U., Dutta, R., Cheema, H., George, J., Sareen, A., Dixit, A., Yuan, Z., Giri, B., Meng, J., Banerjee, S., Banerjee, S., Dudeja, V., Dawra, R., Roy, S. & Saluja, A., Apr 1 2018, In: Gut. 67, 4, p. 719-727 9 p.

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

2019

Hepatocellular carcinoma: resection with adjuvant hepatic artery infusion therapy vs resection alone. A systematic review and meta-analysis

Moran, A., Ramos, L. F., Picado, O., Pendola, F., Sleeman, D., Dudeja, V., Merchant, N. & Yakoub, D., Mar 15 2019, In: Journal of surgical oncology. 119, 4, p. 455-463 9 p.

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

2016

Evolution of novel therapeutic options for pancreatic cancer

Saluja, A. K., Dudeja, V. & Banerjee, S., Sep 1 2016, In: Current opinion in gastroenterology. 32, 5, p. 401-407 7 p.

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

2019

Survival Outcomes Associated with Clinical and Pathological Response Following Neoadjuvant FOLFIRINOX or Gemcitabine/Nab-Paclitaxel Chemotherapy in Resected Pancreatic Cancer

Macedo, F. I., Ryon, E., Maithel, S. K., Lee, R. M., Kooby, D. A., Fields, R. C., Hawkins, W. G., Williams, G., Maduekwe, U., Kim, H. J., Ahmad, S. A., Patel, S. H., Abbott, D. E., Schwartz, P., Weber, S. M., Scoggins, C. R., Martin, R. C. G., Dudeja, V., Franceschi, D., Livingstone, A. S. & 1 others, Merchant, N. B., Sep 1 2019, In: Annals of surgery. 270, 3, p. 400-413 14 p.

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

2016

Comprehensive analysis of microRNA signature of mouse pancreatic acini: Overexpression of miR-21-3p in acute pancreatitis

Dixit, A. K., Sarver, A. E., Yuan, Z., George, J., Barlass, U., Cheema, H., Sareen, A., Banerjee, S., Dudeja, V., Dawra, R., Subramanian, S. & Saluja, A. K., 2016, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 311, 5, p. G974-G980

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

2020

Erratum: Prosurvival role of heat shock factor 1 in the pathogenesis of pancreatobiliary tumors (American Journal of Physiology - Gastrointestinal and Liver Physiology (2011) 300 (G948-G955) DOI: 10.1152/ajpgi.00346.2010)

Dudeja, V., Chugh, R. K., Sangwan, V., Skube, S. J., Mujumdar, N. R., Antonoff, M. B., Dawra, R. K., Vickers, S. M. & Saluja, A. K., May 2020, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 318, 5, p. G988

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

2016

Effect of MRI versus MDCT on Milan criteria scores and liver transplantation eligibility

Rostambeigi, N., Taylor, A. J., Golzarian, J., Jensen, E. H., Pruett, T. L., Dudeja, V. & D'souza, D., Apr 1 2016, In: American Journal of Roentgenology. 206, 4, p. 726-733 8 p.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

2019

Correction: Triptolide-induced cell death in pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1 (Journal of Biological Chemistry (2013) 288 (33927-33938) DOI: 10.1074/jbc.M113.500983)

Banerjee, S., Sangwan, V., McGinn, O., Chugh, R., Dudeja, V., Vickers, S. M. & Saluja, A. K., Jul 5 2019, In: Journal of Biological Chemistry. 294, 27, p. 10739 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

2017

Systemic Chemotherapy Combined with Resection for Locally Advanced Gallbladder Carcinoma: Surgical and Survival Outcomes

Creasy, J. M., Goldman, D. A., Dudeja, V., Lowery, M. A., Cercek, A., Balachandran, V. P., Allen, P. J., DeMatteo, R. P., Kingham, T. P., D'Angelica, M. I. & Jarnagin, W. R., May 2017, In: Journal of the American College of Surgeons. 224, 5, p. 906-916 11 p.

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

2019

Unconventional T cells in the pancreatic tumor microenvironment: Thinking outside the box

Banerjee, S., Dudeja, V. & Saluja, A., 2019, In: Cancer discovery. 9, 9, p. 1164-1166 3 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

2011

Myricetin induces pancreatic cancer cell death via the induction of apoptosis and inhibition of the phosphatidylinositol 3-kinase (PI3K) signaling pathway

Phillips, P. A., Sangwan, V., Borja-Cacho, D., Dudeja, V., Vickers, S. M. & Saluja, A. K., Sep 28 2011, In: Cancer letters. 308, 2, p. 181-188 8 p.

Research output: Contribution to journal › Article › peer-review

83 Scopus citations

2015

Neutrophil Extracellular Traps Provide a Grip on the Enigmatic Pathogenesis of Acute Pancreatitis

Korhonen, J. T., Dudeja, V., Dawra, R., Kubes, P. & Saluja, A., Dec 1 2015, In: Gastroenterology. 149, 7, p. 1682-1685 4 p.

Research output: Contribution to journal › Editorial › peer-review

3 Scopus citations

2016

A Novel Immunocompetent Mouse Model of Pancreatic Cancer with Robust Stroma: a Valuable Tool for Preclinical Evaluation of New Therapies

Majumder, K., Arora, N., Modi, S., Chugh, R., Nomura, A., Giri, B., Dawra, R., Ramakrishnan, S., Banerjee, S., Saluja, A. & Dudeja, V., Jan 1 2016, In: Journal of Gastrointestinal Surgery. 20, 1, p. 53-65 13 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

2012

MUC1c regulates cell survival in pancreatic cancer by preventing lysosomal permeabilization

Banerjee, S., Mujumdar, N., Dudeja, V., Mackenzie, T., Krosch, T. K., Sangwan, V., Vickers, S. M. & Saluja, A. K., Aug 13 2012, In: PloS one. 7, 8, e43020.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

2015

Minnelide effectively eliminates CD133⁺ side population in pancreatic cancer

Nomura, A., McGinn, O., Dudeja, V., Sangwan, V., Saluja, A. K. & Banerjee, S., Nov 23 2015, In: Molecular Cancer. 14, 1, 200.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

2014

CD133+ tumor initiating cells in a syngenic murine model of pancreatic cancer respond to minnelide

Banerjee, S., Nomura, A., Sangwan, V., Chugh, R., Dudeja, V., Vickers, S. M. & Saluja, A., May 1 2014, In: Clinical Cancer Research. 20, 9, p. 2388-2399 12 p.

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Endoplasmic reticulum stress is chronically activated in chronic pancreatitis

Sah, R. P., Garg, S. K., Dixit, A. K., Dudeja, V., Dawra, R. K. & Saluja, A. K., Oct 3 2014, In: Journal of Biological Chemistry. 289, 40, p. 27551-27561 11 p.

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

2020

Targeting tumor-intrinsic hexosamine biosynthesis sensitizes pancreatic cancer to anti-PD1 therapy

Sharma, N. S., Gupta, V. K., Garrido, V. T., Hadad, R., Durden, B. C., Kesh, K., Giri, B., Ferrantella, A., Dudeja, V., Saluja, A. & Banerjee, S., Jan 2 2020, In: Journal of Clinical Investigation. 130, 1, p. 451-465 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2015

Triptolide abrogates growth of colon cancer and induces cell cycle arrest by inhibiting transcriptional activation of E2F

Oliveira, A. R., Beyer, G., Chugh, R., Skube, S. J., Majumder, K., Banerjee, S., Sangwan, V., Li, L., Dawra, R. K., Subramanian, S., Saluja, A. K. & Dudeja, V., Jun 28 2015, In: Laboratory Investigation. 95, 6, p. 648-659 12 p.

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

2018

GRP78-mediated antioxidant response and ABC transporter activity confers chemoresistance to pancreatic cancer cells

Dauer, P., Sharma, N. S., Gupta, V. K., Nomura, A., Dudeja, V., Saluja, A. & Banerjee, S., Sep 2018, In: Molecular Oncology. 12, 9, p. 1498-1512 15 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

2019

The Role of the Microbiome in Immunologic Development and its Implication For Pancreatic Cancer Immunotherapy

Sethi, V., Vitiello, G. A., Saxena, D., Miller, G. & Dudeja, V., May 2019, In: Gastroenterology. 156, 7, p. 2097-2115.e2

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Early Intra-Acinar Events in Pathogenesis of Pancreatitis

Saluja, A., Dudeja, V., Dawra, R. & Sah, R. P., May 1 2019, In: Gastroenterology. 156, 7, p. 1979-1993 15 p.

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Evolution of surgical management of gallbladder carcinoma and impact on outcome: results from two decades at a single-institution

Creasy, J. M., Goldman, D. A., Gonen, M., Dudeja, V., O'Reilly, E. M., Abou-Alfa, G. K., Cercek, A., Harding, J. J., Balachandran, V. P., Drebin, J. A., Allen, P. J., Kingham, T. P., D'Angelica, M. I. & Jarnagin, W. R., Nov 2019, In: HPB. 21, 11, p. 1541-1551 11 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

2018

NFκB-mediated invasiveness in CD133⁺ pancreatic TICs is regulated by autocrine and paracrine activation of IL1 signaling

Nomura, A., Gupta, V. K., Dauer, P., Sharma, N. S., Dudeja, V., Merchant, N., Saluja, A. K. & Banerjee, S., Jan 2018, In: Molecular Cancer Research. 16, 1, p. 162-172 11 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

2019

Correction to: Pre-clinical evaluation of Minnelide as a therapy for acute myeloid leukemia (Journal of Translational Medicine (2019) 17 (163 ) DOI: 10.1186/s12967-019-1901-8)

Giri, B., Gupta, V. K., Yaffe, B., Modi, S., Roy, P., Sethi, V., Lavania, S. P., Vickers, S. M., Dudeja, V., Banerjee, S., Watts, J. & Saluja, A., Sep 4 2019, In: Journal of translational medicine. 17, 1, 301.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

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