Find Research Outputs

Search in all content

Filters for Research Output

Search concepts
Selected Filters

Publication Year

  • 2020
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011

Author

  • Ralf Paus
2017

Oxidative stress management in the hair follicle: Could targeting NRF2 counter age-related hair disorders and beyond?

Jadkauskaite, L., Coulombe, P. A., Schäfer, M., Dinkova-Kostova, A. T., Paus, R. & Haslam, I. S., Aug 1 2017, In : BioEssays. 39, 8, 1700029.

Research output: Contribution to journalReview article

12 Scopus citations
2011

In search of the source of hyperprolactinaemia in systemic lupus erythematosus

Langan, E. A., Griffiths, C. E. M. & Paus, R., Dec 1 2011, In : Clinical and Experimental Rheumatology. 29, 6, 1 p.

Research output: Contribution to journalLetter

1 Scopus citations
2012

Immunohistological pointers to a possible role for excessive cathelicidin (LL-37) expression by apocrine sweat glands in the pathogenesis of hidradenitis suppurativa/acne inversa

Emelianov, V. U., Bechara, F. G., Gläser, R., Langan, E. A., Taungjaruwinai, W. M., Schröder, J. M., Meyer, K. C. & Paus, R., May 1 2012, In : British Journal of Dermatology. 166, 5, p. 1023-1034 12 p.

Research output: Contribution to journalArticle

59 Scopus citations
2018

Cover Image: Neuroendocrine treatment of inherited keratin disorders by cannabinoids?

Ramot, Y., Oláh, A. & Paus, R., Jun 2018, In : British Journal of Dermatology. 178, 6, 1 p.

Research output: Contribution to journalLetter

5 Scopus citations

Retinoic acid co-treatment aggravates severity of dioxin-induced skin lesions in hairless mice via induction of inflammatory response

Rudyak, S. G., Usakin, L. A., Tverye, E. A., Orekhov, A. S., Belushkina, N. N., Paus, R., Paltsev, M. A. & Panteleyev, A. A., Dec 2 2018, In : Biochemical and biophysical research communications. 506, 4, p. 854-861 8 p.

Research output: Contribution to journalArticle

How chemotherapy and radiotherapy damage the tissue: Comparative biology lessons from feather and hair models

Gao, Q. X., Zhou, G. X., Lin, S. J., Paus, R. & Yue, Z. C., Jan 1 2018, (Accepted/In press) In : Experimental Dermatology.

Research output: Contribution to journalArticle

8 Scopus citations
2016

Exploring the “brain-skin connection”: Leads and lessons from the hair follicle

Paus, R., Oct 1 2016, In : Current Research in Translational Medicine. 64, 4, p. 207-214 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
2015

Resting no more: Re-defining telogen, the maintenance stage of the hair growth cycle

Geyfman, M., Plikus, M. V., Treffeisen, E., Andersen, B. & Paus, R., Jan 1 2015, In : Biological Reviews. 90, 4, p. 1179-1196 18 p.

Research output: Contribution to journalArticle

44 Scopus citations
2017

Wound healing protects against chemotherapy-induced alopecia in young rats via up-regulating interleukin-1β-mediated signaling

Stojadinovic, O., Wikramanayake, T. C., Villasante Fricke, A. C., Yin, N. C., Liang, L., Hinde, E., Escandon, J., Tomic-Canic, M., Ansell, D. M., Paus, R. & Jimenez, J. J., May 2017, In : Heliyon. 3, 5, e00309.

Research output: Contribution to journalArticle

2 Scopus citations
2013

A practical guide for the study of human and murine sebaceous glands in situ

Hinde, E., Haslam, I. S., Schneider, M. R., Langan, E. A., Kloepper, J. E., Schramm, C., Zouboulis, C. C. & Paus, R., Oct 1 2013, In : Experimental dermatology. 22, 10, p. 631-637 7 p.

Research output: Contribution to journalReview article

39 Scopus citations

What causes alopecia areata? Section Editors: Ralf Paus, Manchester/Lübeck and Raymond Cho, San Francisco Controversies in Experimental Dermatology: What causes alopecia areata?

Duque-Estrada, B., Tosti, A., Mcelwee, K. J., Gilhar, A., Keren, A., Bertolini, M., Shoenfeld, Y., Nakamura, M., Tokura, Y., Sundberg, J. P., King, L. E., Ramot, Y., Zlotogorski, A., Tobin, D. J., Paus, R., Inui, S. & Itami, S., Sep 1 2013, In : Experimental dermatology. 22, 9, p. 609-626 18 p.

Research output: Contribution to journalArticle

65 Scopus citations
2011

Cartilage oligomeric matrix protein (COMP) forms part of the connective tissue of normal human hair follicles

De Schellenberger, A. A., Horland, R., Rosowski, M., Paus, R., Lauster, R. & Lindner, G., Apr 1 2011, In : Experimental dermatology. 20, 4, p. 361-366 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
2015

RBM28, a protein deficient in ANE syndrome, regulates hair follicle growth via miR-203 and p63

Warshauer, E., Samuelov, L., Sarig, O., Vodo, D., Bindereif, A., Kanaan, M., Gat, U., Fuchs-Telem, D., Shomron, N., Farberov, L., Pasmanik-Chor, M., Nardini, G., Winkler, E., Meilik, B., Petit, I., Aberdam, D., Paus, R., Sprecher, E. & Nousbeck, J., Aug 1 2015, In : Experimental dermatology. 24, 8, p. 618-622 5 p.

Research output: Contribution to journalArticle

7 Scopus citations
2020

Neuroendocrinology and neurobiology of sebaceous glands

Clayton, R. W., Langan, E. A., Ansell, D. M., de Vos, I. J. H. M., Göbel, K., Schneider, M. R., Picardo, M., Lim, X., van Steensel, M. A. M. & Paus, R., Jun 1 2020, In : Biological Reviews. 95, 3, p. 592-624 33 p.

Research output: Contribution to journalArticle

2015

The role of PPARγ-mediated signalling in skin biology and pathology: New targets and opportunities for clinical dermatology

Ramot, Y., Mastrofrancesco, A., Camera, E., Desreumaux, P., Paus, R. & Picardo, M., Apr 1 2015, In : Experimental dermatology. 24, 4, p. 245-251 7 p.

Research output: Contribution to journalReview article

37 Scopus citations
2011

Erratum: Death deflected: IL-15 inhibits TNF-α-mediated apoptosis in fibroblasts by TRAF2 recruitment to the IL-15Rα chain (FASEB Journal (1999) 13 (1575-1585))

Bulfone-Paus, S., Bulanova, E., Pohl, T., Budagian, V., Dürkop, H., Rückert, R., Kunzendorf, U., Paus, R. & Krause, H., Mar 1 2011, In : FASEB Journal. 25, 3, 1 p.

Research output: Contribution to journalComment/debate

2018

Bi-allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis Simplex

Romano, M. T., Tafazzoli, A., Mattern, M., Sivalingam, S., Wolf, S., Rupp, A., Thiele, H., Altmüller, J., Nürnberg, P., Ellwanger, J., Gambon, R., Baumer, A., Kohlschmidt, N., Metze, D., Holdenrieder, S., Paus, R., Lütjohann, D., Frank, J., Geyer, M., Bertolini, M. & 2 others, Kokordelis, P. & Betz, R. C., Nov 1 2018, In : American Journal of Human Genetics. 103, 5, p. 777-785 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

The renaissance of human skin organ culture: A critical reappraisal

Zhou, L., Zhang, X., Paus, R. & Lu, Z., Nov 1 2018, In : Differentiation. 104, p. 22-35 14 p.

Research output: Contribution to journalReview article

10 Scopus citations
2016

Hunting the genes in male-pattern alopecia: How important are they, how close are we and what will they tell us?

Heilmann-Heimbach, S., Hochfeld, L. M., Paus, R. & Nöthen, M. M., Apr 1 2016, In : Experimental Dermatology. 25, 4, p. 251-257 7 p.

Research output: Contribution to journalReview article

22 Scopus citations
2017

A role for neuregulin-1 in promoting keloid fibroblast migration via ErbB2-mediated signaling

Jumper, N., Hodgkinson, T., Paus, R. & Bayat, A., Jan 1 2017, In : Acta Dermato-Venereologica. 97, 6, p. 675-684 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
2016

Lhx2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth

Tomann, P., Paus, R., Millar, S. E., Scheidereit, C. & Schmidt-Ullrich, R., May 2016, In : Development (Cambridge). 143, 9, p. 1512-1522 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
2018

Visualization of global RNA synthesis in a human (mini-) organ in situ by click chemistry

Purba, T. S., Marsh, J., Ng'andu, K., Kurinna, S. & Paus, R., Aug 1 2018, In : BioTechniques. 65, 2, p. 97-100 4 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2016

A primer for studying cell cycle dynamics of the human hair follicle

Purba, T. S., Brunken, L., Hawkshaw, N. J., Peake, M., Hardman, J. & Paus, R., Sep 1 2016, In : Experimental Dermatology. 25, 9, p. 663-668 6 p.

Research output: Contribution to journalReview article

19 Scopus citations
2015

Mapping the expression of epithelial hair follicle stem cell-related transcription factors LHX2 and SOX9 in the human hair follicle

Purba, T. S., Haslam, I. S., Shahmalak, A., Bhogal, R. K. & Paus, R., Jan 1 2015, In : Experimental Dermatology. 24, 6, p. 462-467 6 p.

Research output: Contribution to journalArticle

15 Scopus citations
2017

Divergent proliferation patterns of distinct human hair follicle epithelial progenitor niches in situ and their differential responsiveness to prostaglandin D2

Purba, T. S., Peake, M., Farjo, B., Farjo, N., Bhogal, R. K., Jenkins, G. & Paus, R., Dec 1 2017, In : Scientific Reports. 7, 1, 15197.

Research output: Contribution to journalArticle

10 Scopus citations
2012

Recurrent episodes of hair loss in a 37 year old woman

Cunningham, C., Paus, R. & Harries, M., Oct 27 2012, In : BMJ (Online). 345, 7880

Research output: Contribution to journalComment/debate

4 Scopus citations
2020

Does mitochondrial dysfunction of hair follicle epithelial stem cells play a role in the pathobiology of lichen planopilaris?

Hardman-Smart, J. A., Purba, T. S., Panicker, S., Farjo, B., Farjo, N., Harries, M. J. & Paus, R., 2020, (Accepted/In press) In : British Journal of Dermatology.

Research output: Contribution to journalLetter

Open Access
2011

Characterization of stem cells in Dupuytren's disease

Hindocha, S., Iqbal, S. A., Farhatullah, S., Paus, R. & Bayat, A., Feb 1 2011, In : British Journal of Surgery. 98, 2, p. 308-315 8 p.

Research output: Contribution to journalArticle

16 Scopus citations
2012

Utilizing the hair follicle to dissect the regulation and autocrine/paracrine activities of prolactin in humans

Langan, E. A., Griffiths, C. E. M. & Paus, R., May 15 2012, In : American Journal of Physiology - Endocrinology and Metabolism. 302, 10, p. E1311-E1312

Research output: Contribution to journalLetter

8 Scopus citations
2017

Site-specific gene expression profiling as a novel strategy for unravelling keloid disease pathobiology

Jumper, N., Hodgkinson, T., Paus, R. & Bayat, A., Mar 2017, In : PloS one. 12, 3, e0172955.

Research output: Contribution to journalArticle

15 Scopus citations
2016

Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis

Fleger-Weckmann, A., Üstün, Y., Kloepper, J., Paus, R., Bloch, W., Chen, Z. L., Wegner, J., Sorokin, L., Langbein, L., Eckes, B., Zigrino, P., Krieg, T. & Nischt, R., Dec 1 2016, In : Matrix Biology. 56, p. 42-56 15 p.

Research output: Contribution to journalArticle

9 Scopus citations
2014

Abnormal interactions between perifollicular mast cells and CD8+ T-cells may contribute to the pathogenesis of alopecia areata

Bertolini, M., Zilio, F., Rossi, A., Kleditzsch, P., Emelianov, V. E., Gilhar, A., Keren, A., Meyer, K. C., Wang, E., Funk, W., McElwee, K. & Paus, R., May 15 2014, In : PloS one. 9, 5, e94260.

Research output: Contribution to journalArticle

61 Scopus citations
2018

Autophagy is essential for maintaining the growth of a human (mini-)organ: Evidence from scalp hair follicle organ culture

Parodi, C., Hardman, J. A., Allavena, G., Marotta, R., Catelani, T., Bertolini, M., Paus, R. & Grimaldi, B., Mar 1 2018, In : PLoS biology. 16, 3, p. e2002864

Research output: Contribution to journalArticle

Open Access
11 Scopus citations
2011

Signaling through P2X7 receptor in human T cells involves p56 lck, MAP kinases, and transcription factors AP-1 and NF-κB

Budagian, V., Bulanova, E., Brovko, L., Orinska, Z., Fayad, R., Paus, R. & Bulfone-Paus, S., Mar 18 2011, In : Journal of Biological Chemistry. 286, 11, 1 p.

Research output: Contribution to journalComment/debate

A neuroendocrinological perspective on human hair follicle pigmentation

Paus, R., Feb 1 2011, In : Pigment Cell and Melanoma Research. 24, 1, p. 89-106 18 p.

Research output: Contribution to journalArticle

32 Scopus citations
2018

iNKT cells ameliorate human autoimmunity: Lessons from alopecia areata

Ghraieb, A., Keren, A., Ginzburg, A., Ullmann, Y., Schrum, A. G., Paus, R. & Gilhar, A., Jul 1 2018, In : Journal of Autoimmunity. 91, p. 61-72 12 p.

Research output: Contribution to journalArticle

4 Scopus citations
2013

Tumour Necrosis Factor Alpha, Interferon Gamma and Substance P Are Novel Modulators of Extrapituitary Prolactin Expression in Human Skin

Langan, E. A., Vidali, S., Pigat, N., Funk, W., Lisztes, E., Bíró, T., Goffin, V., Griffiths, C. E. M. & Paus, R., Apr 23 2013, In : PloS one. 8, 4, e60819.

Research output: Contribution to journalArticle

15 Scopus citations
2018

Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles

Hawkshaw, N. J., Hardman, J. A., Haslam, I. S., Shahmalak, A., Gilhar, A., Lim, X. & Paus, R., May 8 2018, In : PLoS biology. 16, 5, e2003705.

Research output: Contribution to journalArticle

17 Scopus citations
2017

Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation

Ali, N., Zirak, B., Rodriguez, R. S., Pauli, M. L., Truong, H. A., Lai, K., Ahn, R., Corbin, K., Lowe, M. M., Scharschmidt, T. C., Taravati, K., Tan, M. R., Ricardo-Gonzalez, R. R., Nosbaum, A., Bertolini, M., Liao, W., Nestle, F. O., Paus, R., Cotsarelis, G., Abbas, A. K. & 1 others, Rosenblum, M. D., Jun 1 2017, In : Cell. 169, 6, p. 1119-1129.e11

Research output: Contribution to journalArticle

172 Scopus citations
2011

Erratum: A promiscuous liaison between IL-15 receptor and Axl receptor tyrosine kinase in cell death control (The EMBO Journal (2005) 24 (4260-4270) DOI: 10.1038/sj.emboj.7600874)

Budagian, V., Bulanova, E., Orinska, Z., Thon, L., Mamat, U., Bellosta, P., Basilico, C., Adam, D., Paus, R. & Bulfone-Paus, S., Feb 2 2011, In : EMBO Journal. 30, 3, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations
2016

Alopecia areata: Animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies

Gilhar, A., Schrum, A. G., Etzioni, A., Waldmann, H. & Paus, R., Jul 1 2016, In : Autoimmunity Reviews. 15, 7, p. 726-735 10 p.

Research output: Contribution to journalReview article

37 Scopus citations
2020
Open Access
2014
22 Scopus citations
2012

The neuropeptide galanin is a novel inhibitor of human hair growth

Holub, B. S., Kloepper, J. E., Tó Th, B. I., Bíro, T., Kofler, B. & Paus, R., Jul 1 2012, In : British Journal of Dermatology. 167, 1, p. 10-16 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
2011

TRP channels in Cutaneous Biology in health and disease

Bíró, T. & Paus, R., Jul 1 2011, TRP Channels in Health and Disease: Implications for Diagnosis and Therapy. Nova Science Publishers, Inc., p. 331-362 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

A novel in vitro assay for electrophysiological research on human skin fibroblasts: Degenerate electrical waves downregulate collagen I expression in keloid fibroblasts

Sebastian, A., Syed, F., McGrouther, D. A., Colthurst, J., Paus, R. & Bayat, A., Jan 2011, In : Experimental dermatology. 20, 1, p. 64-68 5 p.

Research output: Contribution to journalArticle

19 Scopus citations
2016

The gut-skin axis in health and disease: A paradigm with therapeutic implications

O'Neill, C. A., Monteleone, G., McLaughlin, J. T. & Paus, R., Nov 1 2016, In : BioEssays. 38, 11, p. 1167-1176 10 p.

Research output: Contribution to journalArticle

48 Scopus citations
2012

Long-term organ culture of keloid disease tissue

Bagabir, R., Syed, F., Paus, R. & Bayat, A., May 2012, In : Experimental dermatology. 21, 5, p. 376-381 6 p.

Research output: Contribution to journalReview article

40 Scopus citations
2018

Olfactory receptor OR2AT4 regulates human hair growth

Chéret, J., Bertolini, M., Ponce, L., Lehmann, J., Tsai, T., Alam, M., Hatt, H. & Paus, R., Dec 1 2018, In : Nature Communications. 9, 1, 3624.

Research output: Contribution to journalArticle

12 Scopus citations
2013

β1 integrin signaling maintains human epithelial progenitor cell survival in situ and controls proliferation, apoptosis and migration of their progeny

Ernst, N., Yay, A., Bíró, T., Tiede, S., Humphries, M., Paus, R. & Kloepper, J. E., Dec 27 2013, In : PloS one. 8, 12, e84356.

Research output: Contribution to journalArticle

14 Scopus citations