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  • Ralf Paus
2013

Blocking potassium channels (Kv1.3): A new treatment option for alopecia areata?

Gilhar, A., Keren, A., Shemer, A., Ullmann, Y. & Paus, R., Aug 2013, In : Journal of Investigative Dermatology. 133, 8, p. 2088-2091 4 p.

Research output: Contribution to journalLetter

19 Scopus citations
2020

Non-neuronal kappa-opioid receptor activation enhances epidermal keratinocyte proliferation, and modulates mast cell functions in human skin ex vivo

Chéret, J., Gherardini, J., Soeberdt, M., Hundt, J. E., Abels, C., Bertolini, M. & Paus, R., Jan 1 2020, (Accepted/In press) In : Journal of Dermatology.

Research output: Contribution to journalArticle

2013

Antimicrobial peptides (AMPs) from fish epidermis: Perspectives for investigative dermatology

Rakers, S., Niklasson, L., Steinhagen, D., Kruse, C., Schauber, J., Sundell, K. & Paus, R., May 2013, In : Journal of Investigative Dermatology. 133, 5, p. 1140-1149 10 p.

Research output: Contribution to journalArticle

58 Scopus citations
2016

The Thyroid Hormone Analogue KB2115 (Eprotirome) Prolongs Human Hair Growth (Anagen) Ex Vivo

Oláh, A., Gherardini, J., Bertolini, M., Chéret, J., Ponce, L., Kloepper, J., Bíró, T., Soeberdt, M., Abels, C. & Paus, R., Aug 1 2016, In : Journal of Investigative Dermatology. 136, 8, p. 1711-1714 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis

Peled, A., Sarig, O., Samuelov, L., Bertolini, M., Ziv, L., Weissglas-Volkov, D., Eskin-Schwartz, M., Adase, C. A., Malchin, N., Bochner, R., Fainberg, G., Goldberg, I., Sugawara, K., Baniel, A., Tsuruta, D., Luxenburg, C., Adir, N., Duverger, O., Morasso, M., Shalev, S. & 4 others, Gallo, R. L., Shomron, N., Paus, R. & Sprecher, E., Oct 2016, In : PLoS genetics. 12, 10, e1006369.

Research output: Contribution to journalArticle

11 Scopus citations
2017

Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness

Heilmann-Heimbach, S., Herold, C., Hochfeld, L. M., Hillmer, A. M., Nyholt, D. R., Hecker, J., Javed, A., Chew, E. G. Y., Pechlivanis, S., Drichel, D., Heng, X. T., Del Rosario, R. C. H., Fier, H. L., Paus, R., Rueedi, R., Galesloot, T. E., Moebus, S., Anhalt, T., Prabhakar, S., Li, R. & 16 others, Kanoni, S., Papanikolaou, G., Kutalik, Z., Deloukas, P., Philpott, M. P., Waeber, G., Spector, T. D., Vollenweider, P., Kiemeney, L. A. L. M., Dedoussis, G., Richards, J. B., Nothnagel, M., Martin, N. G., Becker, T., Hinds, D. A. & Nöthen, M. M., Mar 8 2017, In : Nature communications. 8, 14694.

Research output: Contribution to journalArticle

18 Scopus citations
2016

Identification of a Potential Molecular Diagnostic Biomarker in Keloid Disease: Syndecan-1 (CD138) Is Overexpressed in Keloid Scar Tissue

Bagabir, R. A., Syed, F., Shenjere, P., Paus, R. & Bayat, A., Nov 1 2016, In : Journal of Investigative Dermatology. 136, 11, p. 2319-2323 5 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017

Oxidative Damage Control in a Human (Mini-) Organ: Nrf2 Activation Protects against Oxidative Stress-Induced Hair Growth Inhibition

Haslam, I. S., Jadkauskaite, L., Szabó, I. L., Staege, S., Hesebeck-Brinckmann, J., Jenkins, G., Bhogal, R. K., Lim, F. L., Farjo, N., Farjo, B., Bíró, T., Schäfer, M. & Paus, R., Feb 1 2017, In : Journal of Investigative Dermatology. 137, 2, p. 295-304 10 p.

Research output: Contribution to journalArticle

19 Scopus citations
2012

P-cadherin regulates human hair growth and cycling via canonical wnt signaling and transforming growth factor-β2

Samuelov, L., Sprecher, E., Tsuruta, D., Bíró, T., Kloepper, J. E. & Paus, R., Oct 2012, In : Journal of Investigative Dermatology. 132, 10, p. 2332-2341 10 p.

Research output: Contribution to journalArticle

46 Scopus citations
2015

The PDE4 inhibitor, apremilast, suppresses experimentally induced alopecia areata in human skin in vivo

Keren, A., Shemer, A., Ullmann, Y., Paus, R. & Gilhar, A., Jan 1 2015, In : Journal of Dermatological Science. 77, 1, p. 74-76 3 p.

Research output: Contribution to journalLetter

30 Scopus citations
2016

Thyroid Hormones Enhance Mitochondrial Function in Human Epidermis

Vidali, S., Chéret, J., Giesen, M., Haeger, S., Alam, M., Watson, R. E. B., Langton, A. K., Klinger, M., Knuever, J., Funk, W., Kofler, B. & Paus, R., Oct 1 2016, In : Journal of Investigative Dermatology. 136, 10, p. 2003-2012 10 p.

Research output: Contribution to journalArticle

14 Scopus citations
2018

Re-investigating the basement membrane zone of psoriatic epidermal lesions: Is Laminin-511 a new player in Psoriasis Pathogenesis?

Natsumi, A., Sugawara, K., Yasumizu, M., Mizukami, Y., Sano, S., Morita, A., Paus, R. & Tsuruta, D., Jun 1 2018, In : Journal of Histochemistry and Cytochemistry. 66, 12, p. 847-862 16 p.

Research output: Contribution to journalArticle

2 Scopus citations
2019

Getting ready for the next decade of Experimental Dermatology

Plikus, M. V. & Paus, R., Nov 1 2019, In : Experimental dermatology. 28, 11, p. 1199-1200 2 p.

Research output: Contribution to journalEditorial

2012

Expression of Concern

Luger, T. & Paus, R., Mar 1 2012, In : Experimental dermatology. 21, 3, p. 240 1 p.

Research output: Contribution to journalComment/debate

2013

Protection against chemotherapy-induced alopecia: Targeting ATP-binding cassette transporters in the hair follicle?

Haslam, I. S., Pitre, A., Schuetz, J. D. & Paus, R., Nov 2013, In : Trends in Pharmacological Sciences. 34, 11, p. 599-604 6 p.

Research output: Contribution to journalReview article

17 Scopus citations
2012

Exploring the role of prolactin in psoriasis

Langan, E. A., Griffiths, C. E. M. & Paus, R., Mar 1 2012, In : Archives of Dermatological Research. 304, 2, p. 115-118 4 p.

Research output: Contribution to journalShort survey

11 Scopus citations
2019

Hair growth control by innate immunocytes: Perifollicular macrophages revisited

Muneeb, F., Hardman, J. A. & Paus, R., Apr 2019, In : Experimental dermatology. 28, 4, p. 425-431 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
2014

Harnessing neuroendocrine controls of keratin expression: A new therapeutic strategy for skin diseases?

Ramot, Y. & Paus, R., Jul 2014, In : BioEssays. 36, 7, p. 672-686 15 p.

Research output: Contribution to journalArticle

16 Scopus citations
2016

Is the eccrine gland an integral, functionally important component of the human scalp pilosebaceous unit?

Poblet, E., Jiménez-Acosta, F., Hardman, J. A., Escario, E. & Paus, R., Feb 1 2016, In : Experimental Dermatology. 25, 2, p. 149-150 2 p.

Research output: Contribution to journalArticle

12 Scopus citations
2015

Experimental Dermatology launches a new type of manuscript: 'BEDSIDE-TO-BENCH LETTER'

Böhm, M., Paus, R. & Luger, T. A., Jan 1 2015, In : Experimental Dermatology. 24, 9, 1 p.

Research output: Contribution to journalEditorial

2018

Eccrine sweat glands associate with the human hair follicle within a defined compartment of dermal white adipose tissue

Poblet, E., Jimenez, F., Escario-Travesedo, E., Hardman, J. A., Hernández-Hernández, I., Agudo-Mena, J. L., Cabrera-Galvan, J. J., Nicu, C. & Paus, R., May 1 2018, In : British Journal of Dermatology. 178, 5, p. 1163-1172 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Prolactin as a candidate sebotrop(h)ic hormone?

Langan, E. A., Hinde, E. & Paus, R., Jul 1 2018, In : Experimental Dermatology. 27, 7, p. 729-736 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
2012

Calcitonin gene-related peptide (CGRP) may award relative protection from interferon-γ-induced collapse of human hair follicle immune privilege

Kinori, M., Bertolini, M., Funk, W., Samuelov, L., Meyer, K. C., Emelianov, V. U., Hasse, S. & Paus, R., Mar 1 2012, In : Experimental dermatology. 21, 3, p. 223-226 4 p.

Research output: Contribution to journalLetter

21 Scopus citations
2019

Schwann cells as underestimated, major players in human skin physiology and pathology

Bray, E. R., Chéret, J., Yosipovitch, G. & Paus, R., Jan 1 2019, (Accepted/In press) In : Experimental dermatology.

Research output: Contribution to journalArticle

Open Access
2020

Do hair follicles operate as primitive, multifocal kidney-like excretory (mini-) organs?

Carré, J. L., Suzuki, T. & Paus, R., Mar 1 2020, In : Experimental dermatology. 29, 3, p. 357-365 9 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2019

An osteopontin-derived peptide inhibits human hair growth at least in part by decreasing fibroblast growth factor-7 production in outer root sheath keratinocytes

Alam, M., Bertolini, M., Gherardini, J., Keren, A., Ponce, L., Chéret, J., Alenfall, J., Dunér, P., Nilsson, A. H., Gilhar, A. & Paus, R., Jan 1 2019, (Accepted/In press) In : British Journal of Dermatology.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Protection of glucotoxicity by a tripeptide derivative of α-melanocyte-stimulating hormone in human epidermal keratinocytes

Gkogkolou, P., Sarna, M., Sarna, T., Paus, R., Luger, T. A. & Böhm, M., Jan 1 2018, (Accepted/In press) In : British Journal of Dermatology.

Research output: Contribution to journalArticle

3 Scopus citations
2015

N1-methylspermidine, a stable spermidine analog, prolongs anagen and regulates epithelial stem cell functions in human hair follicles

Ramot, Y., Marzani, B., Pinto, D., Kloepper, J. E. & Paus, R., Nov 1 2015, In : Archives of Dermatological Research. 307, 9, p. 841-847 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
2014

α-Melanocyte-stimulating hormone: A protective peptide against chemotherapy-induced hair follicle damage?

Böhm, M., Bodõ, E., Funk, W. & Paus, R., Jan 1 2014, In : British Journal of Dermatology. 170, 4, p. 956-960 5 p.

Research output: Contribution to journalArticle

14 Scopus citations
2017

Cover Image: Are melanocyte-associated peptides the elusive autoantigens in alopecia areata?

Bertolini, M., Rossi, A. & Paus, R., Apr 1 2017, In : British Journal of Dermatology. 176, 4, 1 p.

Research output: Contribution to journalLetter

3 Scopus citations
2012

A function for Rac1 in the terminal differentiation and pigmentation of hair

Behrendt, K., Klatte, J., Pofahl, R., Bloch, W., Smyth, N., Tscharntke, M., Krieg, T., Paus, R., Niessen, C., Niemann, C., Brakebusch, C. & Haase, I., May 1 2012, In : Development. 139, 9, p. 896-905 10 p.

Research output: Contribution to journalArticle

9 Scopus citations
2020

Frontal fibrosing alopecia shows robust T helper 1 and Janus kinase 3 skewing

Del Duca, E., Ruano Ruiz, J., Pavel, A. B., Dutt Sanyal, R., Song, T., Gay-Mimbrera, J., Zhang, N., Estrada, Y. D., Peng, X., Renert-Yuval, Y., Phelps, R. G., Paus, R., Krueger, J. G. & Guttman-Yassky, E., 2020, (Accepted/In press) In : British Journal of Dermatology.

Research output: Contribution to journalArticle

2013

The immune system of mouse vibrissae follicles: Cellular composition and indications of immune privilege

Bertolini, M., Meyer, K. C., Slominski, R., Kobayashi, K., Ludwig, R. J. & Paus, R., Sep 1 2013, In : Experimental dermatology. 22, 9, p. 593-598 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
2016

Vasoactive intestinal peptide, whose receptor-mediated signalling may be defective in alopecia areata, provides protection from hair follicle immune privilege collapse

Bertolini, M., Pretzlaff, M., Sulk, M., Bähr, M., Gherardini, J., Uchida, Y., Reibelt, M., Kinori, M., Rossi, A., Bíró, T. & Paus, R., Sep 1 2016, In : British Journal of Dermatology. 175, 3, p. 531-541 11 p.

Research output: Contribution to journalArticle

14 Scopus citations
2015

Toward high-throughput chip calorimetry by use of segmented-flow technology

Wolf, A., Hartmann, T., Bertolini, M., Schemberg, J., Grodrian, A., Lemke, K., Förster, T., Kessler, E., Hänschke, F., Mertens, F., Paus, R. & Lerchner, J., Mar 10 2015, In : Thermochimica Acta. 603, p. 172-183 12 p.

Research output: Contribution to journalArticle

17 Scopus citations
2019

Nestin + progenitor cells isolated from adult human sweat gland stroma promote reepithelialisation and may stimulate angiogenesis in wounded human skin ex vivo

Liao, T., Lehmann, J., Sternstein, S., Yay, A., Zhang, G., Matthießen, A. E., Schumann, S., Siemers, F., Kruse, C., Hundt, J. E., Langan, E. A., Tiede, S. & Paus, R., Jan 1 2019, In : Archives of Dermatological Research.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2015

Human hair follicle organ culture: Theory, application and perspectiDes

Langan, E. A., Philpott, M. P., Kloepper, J. E. & Paus, R., Jan 1 2015, In : Experimental dermatology. 24, 12, p. 200-215 16 p.

Research output: Contribution to journalArticle

58 Scopus citations
2018

Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution

Cheng, J. B., Sedgewick, A. J., Finnegan, A. I., Harirchian, P., Lee, J., Kwon, S., Fassett, M. S., Golovato, J., Gray, M., Ghadially, R., Liao, W., Perez White, B. E., Mauro, T. M., Mully, T., Kim, E. A., Sbitany, H., Neuhaus, I. M., Grekin, R. C., Yu, S. S., Gray, J. W. & 6 others, Purdom, E., Paus, R., Vaske, C. J., Benz, S. C., Song, J. S. & Cho, R. J., Oct 23 2018, In : Cell Reports. 25, 4, p. 871-883 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Mechanisms of epithelial thickening due to IL-1 signalling blockade and TNF-α administration differ during wound repair and regeneration

Abarca-Buis, R. F., Martínez-Jiménez, A., Vera-Gómez, E., Contreras-Figueroa, M. E., Garciadiego-Cázares, D., Paus, R., Robles-Tenorio, A. & Krötzsch, E., Jan 1 2018, In : Differentiation. 99, p. 10-20 11 p.

Research output: Contribution to journalArticle

7 Scopus citations
2015

Functional histopathology of keloid disease

Jumper, N., Paus, R. & Bayat, A., Jan 1 2015, In : Histology and Histopathology. 30, 9, p. 1033-1057 25 p.

Research output: Contribution to journalReview article

48 Scopus citations
2019

Assessment of Quality of Life and Treatment Outcomes of Patients with Persistent Postchemotherapy Alopecia

Freites-Martinez, A., Chan, D., Sibaud, V., Shapiro, J., Fabbrocini, G., Tosti, A., Cho, J., Goldfarb, S., Modi, S., Gajria, D., Norton, L., Paus, R., Cigler, T. & Lacouture, M. E., Jun 2019, In : JAMA dermatology. 155, 6, p. 724-728 5 p.

Research output: Contribution to journalArticle

4 Scopus citations
2012

Alopecia areata

Gilhar, A., Etzioni, A. & Paus, R., Apr 19 2012, In : New England Journal of Medicine. 366, 16, p. 1515-1525 11 p.

Research output: Contribution to journalReview article

252 Scopus citations
2020

Mitochondrial energy metabolism is negatively regulated by cannabinoid receptor 1 in intact human epidermis

Oláh, A., Alam, M., Chéret, J., Kis, N. G., Hegyi, Z., Szöllősi, A. G., Vidali, S., Bíró, T. & Paus, R., Jan 1 2020, (Accepted/In press) In : Experimental dermatology.

Research output: Contribution to journalArticle

2012

Thyrotropin-releasing hormone controls mitochondrial biology in human epidermis

Knuever, J., Poeggeler, B., Gáspár, E., Klinger, M., Hellwig-Burgel, T., Hardenbicker, C., Tóth, B. I., Bíró, T. & Paus, R., Mar 1 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 3, p. 978-986 9 p.

Research output: Contribution to journalArticle

22 Scopus citations
2014

Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes

Oláh, A., Tóth, B. I., Borbíró, I., Sugawara, K., Szöllõsi, A. G., Czifra, G., Pál, B., Ambrus, L., Kloepper, J., Camera, E., Ludovici, M., Picardo, M., Voets, T., Zouboulis, C. C., Paus, R. & Bíró, T., Sep 2 2014, In : Journal of Clinical Investigation. 124, 9, p. 3713-3724 12 p.

Research output: Contribution to journalArticle

76 Scopus citations
2017

Proceedings of the Ninth World Congress for Hair Research (2015)

Faculty of the Ninth World Congress of Hair Research, Jan 1 2017, In : Journal of Investigative Dermatology Symposium Proceedings. 18, 1, p. S1-S28

Research output: Contribution to journalReview article

2013

Lichen planopilaris is characterized by immune privilege collapse of the hair follicle's epithelial stem cell niche

Harries, M. J., Meyer, K., Chaudhry, I., E Kloepper, J., Poblet, E., Griffiths, C. E. M. & Paus, R., Oct 2013, In : Journal of Pathology. 231, 2, p. 236-247 12 p.

Research output: Contribution to journalArticle

103 Scopus citations
2020

Tissue-resident macrophages can be generated de novo in adult human skin from resident progenitor cells during substance P-mediated neurogenic inflammation ex vivo

Gherardini, J., Uchida, Y., Hardman, J. A., Chéret, J., Mace, K., Bertolini, M. & Paus, R., 2020, In : PloS one. 15, 1, e0227817.

Research output: Contribution to journalArticle

Open Access

Hair(y) Matters in Melanoma Biology

Bedogni, B. & Paus, R., May 2020, In : Trends in Molecular Medicine. 26, 5, p. 441-449 9 p.

Research output: Contribution to journalReview article

1 Scopus citations