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  • Ralf Paus
2014

Deciphering the functions of the hair follicle infundibulum in skin physiology and disease

Schneider, M. R. & Paus, R., Nov 16 2014, In : Cell and Tissue Research. 358, 3, p. 697-704 8 p.

Research output: Contribution to journalReview article

14 Scopus citations
2018

An efficient method for eccrine gland isolation from human scalp

Jimenez, F., Alam, M., Hernandez, I., Poblet, E., Hardman, J. A. & Paus, R., Jun 1 2018, In : Experimental Dermatology. 27, 6, p. 678-681 4 p.

Research output: Contribution to journalArticle

2 Scopus citations
2012

Alopecia areata as a model for T cell-dependent autoimmune diseases.

Bertolini, M., Gilhar, A. & Paus, R., Jun 2012, In : Experimental dermatology. 21, 6, p. 477-479 3 p.

Research output: Contribution to journalArticle

21 Scopus citations
2011

Can the hair follicle become a model for studying selected aspects of human ocular immune privilege?

Kinori, M., Kloepper, J. E. & Paus, R., Jun 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 7, p. 4447-4458 12 p.

Research output: Contribution to journalArticle

14 Scopus citations
2019

Fluorescent cell tracer dye permits real-time assessment of re-epithelialization in a serum-free ex vivo human skin wound assay

Nasir, N. A. M., Paus, R. & Ansell, D. M., Jan 1 2019, In : Wound Repair and Regeneration. 27, 1, p. 126-133 8 p.

Research output: Contribution to journalArticle

3 Scopus citations
2020

Fluoxetine promotes human hair follicle pigmentation ex vivo: serotonin reuptake inhibition as a new antigreying strategy?

Chéret, J., Gherardini, J., Bertolini, M. & Paus, R., Jun 1 2020, In : British Journal of Dermatology. 182, 6, p. 1492-1494 3 p.

Research output: Contribution to journalLetter

2017

Two olfactory receptors—OR2A4/7 and OR51B5—differentially affect epidermal proliferation and differentiation

Tsai, T., Veitinger, S., Peek, I., Busse, D., Eckardt, J., Vladimirova, D., Jovancevic, N., Wojcik, S., Gisselmann, G., Altmüller, J., Ständer, S., Luger, T., Paus, R., Cheret, J. & Hatt, H., Jan 1 2017, In : Experimental dermatology. 26, 1, p. 58-65 8 p.

Research output: Contribution to journalArticle

21 Scopus citations
2014

SIRT2 as a new player in epigenetic programming of keratinocyte differentiation and a candidate tumor suppressor

Wang, M., Yue, Z., Paus, R. & Ramot, Y., Jan 1 2014, In : Experimental Dermatology. 23, 9, p. 636-638 3 p.

Research output: Contribution to journalComment/debate

8 Scopus citations
2015

Differential expression and functionality of ATP-binding cassette transporters in the human hair follicle

Haslam, I. S., El-Chami, C., Faruqi, H., Shahmalak, A., O'Neill, C. A. & Paus, R., Jun 1 2015, In : British Journal of Dermatology. 172, 6, p. 1562-1572 11 p.

Research output: Contribution to journalArticle

14 Scopus citations
2012

Site-specific immunophenotyping of keloid disease demonstrates immune upregulation and the presence of lymphoid aggregates

Bagabir, R., Byers, R. J., Chaudhry, I. H., Müller, W., Paus, R. & Bayat, A., Nov 1 2012, In : British Journal of Dermatology. 167, 5, p. 1053-1066 14 p.

Research output: Contribution to journalArticle

42 Scopus citations
2018

How UV Light Touches the Brain and Endocrine System Through Skin, and Why

Slominski, A. T., Zmijewski, M. A., Plonka, P. M., Szaflarski, J. P. & Paus, R., May 1 2018, In : Endocrinology. 159, 5, p. 1992-2007 16 p.

Research output: Contribution to journalReview article

73 Scopus citations

Is prolactin a negative neuroendocrine regulator of human skin re-epithelisation after wounding?

Langan, E. A., Fink, T. & Paus, R., Dec 1 2018, In : Archives of Dermatological Research. 310, 10, p. 833-841 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
2013

Pathobiology of chemotherapy-induced hair loss

Paus, R., Haslam, I. S., Sharov, A. A. & Botchkarev, V. A., Feb 1 2013, In : The Lancet Oncology. 14, 2, p. e50-e59

Research output: Contribution to journalReview article

109 Scopus citations
2019

Seborrheic dermatitis—Looking beyond Malassezia

Wikramanayake, T. C., Borda, L. J., Miteva, M. & Paus, R., Jan 1 2019, (Accepted/In press) In : Experimental dermatology.

Research output: Contribution to journalReview article

4 Scopus citations
2018

Dermal white adipose tissue undergoes major morphological changes during the spontaneous and induced murine hair follicle cycling: a reappraisal

Foster, A. R., Nicu, C., Schneider, M. R., Hinde, E. & Paus, R., Jul 1 2018, In : Archives of Dermatological Research. 310, 5, p. 453-462 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
2014

Neuroendocrinology of the hair follicle: Principles and clinical perspectives

Paus, R., Langan, E. A., Vidali, S., Ramot, Y. & Andersen, B., Oct 1 2014, In : Trends in Molecular Medicine. 20, 10, p. 559-570 12 p.

Research output: Contribution to journalReview article

54 Scopus citations
2011

Receptor activator of NF-κB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit

Duheron, V., Hess, E., Duval, M., Decossas, M., Castaned, B., Klöpper, J. E., Amoas, L., Barbaroux, J. B., Williams, I. R., Yagita, H., Penninger, J., Choi, Y., Lézot, F., Groves, R., Paus, R. & Mueller, C. G., Mar 29 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 13, p. 5342-5347 6 p.

Research output: Contribution to journalArticle

42 Scopus citations

The IL-15Rα chain signals through association with syk in human B cells (The Journal of Immunology (2001) 167, (6292-6302))

Bulanova, E., Budagian, V., Pohl, T., Krause, H., Dürkop, H., Paus, R. & Bulfone-Paus, S., Feb 15 2011, In : Journal of Immunology. 186, 4, 1 p.

Research output: Contribution to journalComment/debate

Mast cells express novel functional IL-15 receptor α isoforms (The Journal of Immunology (2003) 170, (5045-5055))

Bulanova, E., Budagian, V., Orinska, Z., Krause, H., Paus, R. & Bulfone-Paus, S., Feb 15 2011, In : Journal of Immunology. 186, 4, 1 p.

Research output: Contribution to journalComment/debate

2019

Hair disorders in patients with cancer

Freites-Martinez, A., Shapiro, J., Goldfarb, S., Nangia, J., Jimenez, J. J., Paus, R. & Lacouture, M. E., May 2019, In : Journal of the American Academy of Dermatology. 80, 5, p. 1179-1196 18 p.

Research output: Contribution to journalReview article

10 Scopus citations
2018

Delayed Hair Follicle Morphogenesis and Hair Follicle Dystrophy in a Lipoatrophy Mouse Model of Pparg Total Deletion

Sardella, C., Winkler, C., Quignodon, L., Hardman, J. A., Toffoli, B., Giordano Attianese, G. M. P., Hundt, J. E., Michalik, L., Vinson, C. R., Paus, R., Desvergne, B. & Gilardi, F., Mar 1 2018, In : Journal of Investigative Dermatology. 138, 3, p. 500-510 11 p.

Research output: Contribution to journalArticle

15 Scopus citations
2019

Transepidermal UV radiation of scalp skin ex vivo induces hair follicle damage that is alleviated by the topical treatment with caffeine

Gherardini, J., Wegner, J., Chéret, J., Ghatak, S., Lehmann, J., Alam, M., Jimenez, F., Funk, W., Böhm, M., Botchkareva, N. V., Ward, C., Paus, R. & Bertolini, M., Apr 1 2019, In : International journal of cosmetic science. 41, 2, p. 164-182 19 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2015

Thyroxine differentially modulates the peripheral clock: Lessons from the human hair follicle

Hardman, J. A., Haslam, I. S., Farjo, N., Farjo, B. & Paus, R., Mar 30 2015, In : PloS one. 10, 3, e0121878.

Research output: Contribution to journalArticle

14 Scopus citations
2013

A simple culture method for epithelial stem cells derived from human hair follicle

Hilmi, A. B. M., Halim, A. S., Noor, N. M., Lim, C. K., Idris, Z., Pohchi, A., Asma, H., Wahab, S. F. A., Tiede, S. & Paus, R., Mar 12 2013, In : Central European Journal of Biology. 8, 5, p. 432-439 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
2011

2,4,6-Octatrienoic acid is a novel promoter of melanogenesis and antioxidant defence in normal human melanocytes via PPAR-γ activation

Flori, E., Mastrofrancesco, A., Kovacs, D., Ramot, Y., Briganti, S., Bellei, B., Paus, R. & Picardo, M., Aug 1 2011, In : Pigment Cell and Melanoma Research. 24, 4, p. 618-630 13 p.

Research output: Contribution to journalArticle

33 Scopus citations
2015

Toward the Clonotype Analysis of Alopecia Areata-Specific, Intralesional Human CD8+ T Lymphocytes

Bertolini, M., Uchida, Y. & Paus, R., Nov 1 2015, In : Journal of Investigative Dermatology Symposium Proceedings. 17, 2, p. 9-12 4 p.

Research output: Contribution to journalReview article

9 Scopus citations
2016

Sebaceous lipids are essential for water repulsion, protection against UVB-induced apoptosis and ocular integrity in mice

Dahlhoff, M., Camera, E., Schäfer, M., Emrich, D., Riethmacher, D., Foster, A., Paus, R. & Schneider, M. R., May 15 2016, In : Development (Cambridge). 143, 10, p. 1823-1831 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
2018

Innate lymphoid cells 3 induce psoriasis in xenotransplanted healthy human skin

Keren, A., Shemer, A., Ginzburg, A., Ullmann, Y., Schrum, A. G., Paus, R. & Gilhar, A., Jul 1 2018, In : Journal of Allergy and Clinical Immunology. 142, 1, p. 305-308.e6

Research output: Contribution to journalArticle

10 Scopus citations
2015

Towards a consensus on how to diagnose and quantify female pattern hair loss - The 'Female Pattern Hair Loss Severity Index (FPHL-SI)'

Harries, M., Tosti, A., Bergfeld, W., Blume-Peytavi, U., Shapiro, J., Lutz, G., Messenger, A., Sinclair, R. & Paus, R., 2015, (Accepted/In press) In : Journal of the European Academy of Dermatology and Venereology.

Research output: Contribution to journalArticle

10 Scopus citations
2013

Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin.

Meier, N. T., Haslam, I. S., Pattwell, D. M., Zhang, G. Y., Emelianov, V., Paredes, R., Debus, S., Augustin, M., Funk, W., Amaya, E., Kloepper, J. E., Hardman, M. J. & Paus, R., 2013, In : PloS one. 8, 9, e73596.

Research output: Contribution to journalArticle

28 Scopus citations
2019

Frontiers in alopecia areata pathobiology research

Gilhar, A., Laufer-Britva, R., Keren, A. & Paus, R., Dec 2019, In : Journal of Allergy and Clinical Immunology. 144, 6, p. 1478-1489 12 p.

Research output: Contribution to journalReview article

3 Scopus citations
2020
Open Access
2012

Keloid disease can be inhibited by antagonizing excessive mTOR signaling with a novel dual TORC1/2 inhibitor

Syed, F., Sherris, D., Paus, R., Varmeh, S., Pandolfi, P. P. & Bayat, A., Nov 2012, In : American Journal of Pathology. 181, 5, p. 1642-1658 17 p.

Research output: Contribution to journalArticle

26 Scopus citations
2020

Toward Predicting the Spatio-Temporal Dynamics of Alopecia Areata Lesions Using Partial Differential Equation Analysis

Dobreva, A., Paus, R. & Cogan, N. G., Mar 1 2020, In : Bulletin of Mathematical Biology. 82, 3, 34.

Research output: Contribution to journalArticle

2013

Is thyrotropin-releasing hormone a novel neuroendocrine modulator of keratin expression in human skin?

Ramot, Y., Zhang, G., Bírõ, T., Langbein, L. & Paus, R., Jul 2013, In : British Journal of Dermatology. 169, 1, p. 146-151 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Dopamine is a novel, direct inducer of catagen in human scalp hair follicles in vitro

Langan, E. A., Lisztes, E., Bíro, T., Funk, W., Kloepper, J. E., Griffiths, C. E. M. & Paus, R., Mar 1 2013, In : British Journal of Dermatology. 168, 3, p. 520-525 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
2014

From frog integument to human skin: Dermatological perspectives from frog skin biology

Haslam, I. S., Roubos, E. W., Mangoni, M. L., Yoshizato, K., Vaudry, H., Kloepper, J. E., Pattwell, D. M., Maderson, P. F. A. & Paus, R., Aug 2014, In : Biological Reviews. 89, 3, p. 618-655 38 p.

Research output: Contribution to journalArticle

24 Scopus citations
2017

Characterisation of cell cycle arrest and terminal differentiation in a maximally proliferative human epithelial tissue: Lessons from the human hair follicle matrix

Purba, T. S., Brunken, L., Peake, M., Shahmalak, A., Chaves, A., Poblet, E., Ceballos, L., Gandarillas, A. & Paus, R., Sep 1 2017, In : European Journal of Cell Biology. 96, 6, p. 632-641 10 p.

Research output: Contribution to journalArticle

13 Scopus citations
2012

Primary cicatricial alopecias: A U.K. survey

Griffin, L. L., Michaelides, C., Griffiths, C. E. M., Paus, R. & Harries, M. J., Sep 1 2012, In : British Journal of Dermatology. 167, 3, p. 694-697 4 p.

Research output: Contribution to journalLetter

17 Scopus citations

Lichen planopilaris following hair transplantation and face-lift surgery

Chiang, Y. Z., Tosti, A., Chaudhry, I. H., Lyne, L., Farjo, B., Farjo, N., Cadore De Farias, D., Griffiths, C. E. M., Paus, R. & Harries, M. J., Mar 2012, In : British Journal of Dermatology. 166, 3, p. 666-370 297 p.

Research output: Contribution to journalArticle

38 Scopus citations
2014

Human epithelial hair follicle stem cells and their progeny: Current state of knowledge, the widening gap in translational research and future challenges

Purba, T. S., Haslam, I. S., Poblet, E., Jiménez, F., Gandarillas, A., Izeta, A. & Paus, R., May 2014, In : BioEssays. 36, 5, p. 513-525 13 p.

Research output: Contribution to journalArticle

71 Scopus citations
2013

Autoimmune disease induction in a healthy human organ: A humanized mouse model of alopecia areata

Gilhar, A., Keren, A., Shemer, A., D'Ovidio, R., Ullmann, Y. & Paus, R., Mar 2013, In : Journal of Investigative Dermatology. 133, 3, p. 844-847 4 p.

Research output: Contribution to journalLetter

41 Scopus citations
2016

Hair Follicle Bulge Stem Cells Appear Dispensable for the Acute Phase of Wound Re-epithelialization

Garcin, C. L., Ansell, D. M., Headon, D. J., Paus, R. & Hardman, M. J., May 1 2016, In : STEM CELLS. 34, 5, p. 1377-1385 9 p.

Research output: Contribution to journalArticle

23 Scopus citations
2015

Testing chemotherapeutic agents in the feather follicle identifies a selective blockade of cell proliferation and a key role for sonic hedgehog signaling in chemotherapy-induced tissue damage

Xie, G., Wang, H., Yan, Z., Cai, L., Zhou, G., He, W., Paus, R. & Yue, Z., Mar 12 2015, In : Journal of Investigative Dermatology. 135, 3, p. 690-700 11 p.

Research output: Contribution to journalArticle

18 Scopus citations
2017

E-Cadherin–Mediated Cell Contact Controls the Epidermal Damage Response in Radiation Dermatitis

Xie, G., Ao, X., Lin, T., Zhou, G., Wang, M., Wang, H., Chen, Y., Li, X., Xu, B., He, W., Han, H., Ramot, Y., Paus, R. & Yue, Z., Aug 2017, In : Journal of Investigative Dermatology. 137, 8, p. 1731-1739 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
2019

Human Perifollicular Macrophages Undergo Apoptosis, Express Wnt Ligands, and Switch their Polarization during Catagen

Hardman, J. A., Muneeb, F., Pople, J., Bhogal, R., Shahmalak, A. & Paus, R., Dec 2019, In : Journal of Investigative Dermatology. 139, 12, p. 2543-2546.e9

Research output: Contribution to journalArticle

2 Scopus citations
2011

TSH is a novel neuroendocrine regulator of selected keratins in the human hair follicle

Ramot, Y., Zhang, G., Bíró, T., Lisztes, E., Funk, W., Ingber, A., Langbein, L. & Paus, R., Oct 1 2011, In : Journal of dermatological science. 64, 1, p. 67-70 4 p.

Research output: Contribution to journalLetter

6 Scopus citations
2019

Growth Hormone Operates as a Neuroendocrine Regulator of Human Hair Growth Ex Vivo

Alam, M., Below, D. A., Chéret, J., Langan, E. A., Bertolini, M., Jimenez, F. & Paus, R., Jul 2019, In : Journal of Investigative Dermatology. 139, 7, p. 1593-1596 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
2013

A novel control of human keratin expression: Cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytes in vitro and in situ

Ramot, Y., Sugawara, K., Zákány, N., Tóth, B. I., Bíró, T. & Paus, R., 2013, In : PeerJ. 2013, 1, e40.

Research output: Contribution to journalArticle

26 Scopus citations
2014

A meeting of two chronobiological systems: Circadian proteins period1 and bmal1 modulate the human hair cycle clock

Al-Nuaimi, Y., Hardman, J. A., Bíró, T., Haslam, I. S., Philpott, M. P., Tóth, B. I., Farjo, N., Farjo, B., Baier, G., Watson, R. E. B., Grimaldi, B., Kloepper, J. E. & Paus, R., Mar 2014, In : Journal of Investigative Dermatology. 134, 3, p. 610-619 10 p.

Research output: Contribution to journalArticle

36 Scopus citations