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  • Ralf Paus
2013

Ex vivo evaluation of antifibrotic compounds in skin scarring: EGCG and silencing of PAI-1 independently inhibit growth and induce keloid shrinkage

Syed, F., Bagabir, R. A., Paus, R. & Bayat, A., Aug 1 2013, In : Laboratory Investigation. 93, 8, p. 946-960 15 p.

Research output: Contribution to journalArticle

24 Scopus citations
2019

Theophylline exerts complex anti-ageing and anti-cytotoxicity effects in human skin ex vivo

Bertolini, M., Ramot, Y., Gherardini, J., Heinen, G., Chéret, J., Welss, T., Giesen, M., Funk, W. & Paus, R., Jan 1 2019, (Accepted/In press) In : International journal of cosmetic science.

Research output: Contribution to journalArticle

1 Scopus citations
2014

Advanced inhibition of undesired human hair growth by pparγ modulation?

Ramot, Y., Mastrofrancesco, A., Herczeg-Lisztes, E., Bíró, T., Picardo, M., Kloepper, J. E. & Paus, R., Apr 2014, In : Journal of Investigative Dermatology. 134, 4, p. 1128-1131 4 p.

Research output: Contribution to journalLetter

18 Scopus citations

Hypothalamic-pituitary-thyroid axis hormones stimulate mitochondrial function and biogenesis in human hair follicles

Vidali, S., Knuever, J., Lerchner, J., Giesen, M., Bíró, T., Klinger, M., Kofler, B., Funk, W., Poeggeler, B. & Paus, R., Jan 2014, In : Journal of Investigative Dermatology. 134, 1, p. 33-42 10 p.

Research output: Contribution to journalArticle

36 Scopus citations
2013

Antimicrobial peptides (AMPs) from fish epidermis: Perspectives for investigative dermatology

Rakers, S., Niklasson, L., Steinhagen, D., Kruse, C., Schauber, J., Sundell, K. & Paus, R., May 2013, In : Journal of Investigative Dermatology. 133, 5, p. 1140-1149 10 p.

Research output: Contribution to journalArticle

56 Scopus citations
2019

Human Perifollicular Macrophages Undergo Apoptosis, Express Wnt Ligands, and Switch their Polarization during Catagen

Hardman, J. A., Muneeb, F., Pople, J., Bhogal, R., Shahmalak, A. & Paus, R., Dec 2019, In : Journal of Investigative Dermatology. 139, 12, p. 2543-2546.e9

Research output: Contribution to journalArticle

2 Scopus citations
2013

Tumour Necrosis Factor Alpha, Interferon Gamma and Substance P Are Novel Modulators of Extrapituitary Prolactin Expression in Human Skin

Langan, E. A., Vidali, S., Pigat, N., Funk, W., Lisztes, E., Bíró, T., Goffin, V., Griffiths, C. E. M. & Paus, R., Apr 23 2013, In : PloS one. 8, 4, e60819.

Research output: Contribution to journalArticle

15 Scopus citations
2011

Retraction: Mast cells express novel functional IL-15 receptor α isoforms.

Krause, H., Paus, R., Orinska, Z. & Bulfone-Paus, S., Feb 15 2011, In : Journal of immunology (Baltimore, Md. : 1950). 186, 4, 1 p.

Research output: Contribution to journalComment/debate

2013

Blocking potassium channels (Kv1.3): A new treatment option for alopecia areata?

Gilhar, A., Keren, A., Shemer, A., Ullmann, Y. & Paus, R., Aug 2013, In : Journal of Investigative Dermatology. 133, 8, p. 2088-2091 4 p.

Research output: Contribution to journalLetter

19 Scopus citations
2016

Identification of a Potential Molecular Diagnostic Biomarker in Keloid Disease: Syndecan-1 (CD138) Is Overexpressed in Keloid Scar Tissue

Bagabir, R. A., Syed, F., Shenjere, P., Paus, R. & Bayat, A., Nov 1 2016, In : Journal of Investigative Dermatology. 136, 11, p. 2319-2323 5 p.

Research output: Contribution to journalArticle

5 Scopus citations
2019

Hair disorders in cancer survivors

Freites-Martinez, A., Shapiro, J., van den Hurk, C., Goldfarb, S., Jimenez, J. J., Rossi, A. M., Paus, R. & Lacouture, M. E., May 2019, In : Journal of the American Academy of Dermatology. 80, 5, p. 1199-1213 15 p.

Research output: Contribution to journalReview article

8 Scopus citations
2011

Thyrotropin-releasing hormone selectively stimulates human hair follicle pigmentation

Gáspár, E., Nguyen-Thi, K. T., Hardenbicker, C., Tiede, S., Plate, C., Bodó, E., Knuever, J., Funk, W., Bíró, T. & Paus, R., Dec 2011, In : Journal of Investigative Dermatology. 131, 12, p. 2368-2377 10 p.

Research output: Contribution to journalArticle

23 Scopus citations
2019

Inhibition of ATP binding cassette transporter B1 sensitizes human hair follicles to chemotherapy-induced damage

Smart, E., Farjo, N., Farjo, B., Haslam, I. S. & Paus, R., Jul 2019, In : Journal of dermatological science. 95, 1, p. 44-47 4 p.

Research output: Contribution to journalLetter

Open Access
1 Scopus citations
2012

The authors reply

Gilhar, A., Etzioni, A. & Paus, R., Jul 19 2012, In : New England Journal of Medicine. 367, 3, 1 p.

Research output: Contribution to journalLetter

2011

A neuroendocrinological perspective on human hair follicle pigmentation

Paus, R., Feb 1 2011, In : Pigment Cell and Melanoma Research. 24, 1, p. 89-106 18 p.

Research output: Contribution to journalArticle

32 Scopus citations
2013

Migrating melanocyte stem cells: Masters of disaster?

Paus, R., Jul 1 2013, In : Nature medicine. 19, 7, p. 818-819 2 p.

Research output: Contribution to journalArticle

15 Scopus citations
2018

Melatonin: A Cutaneous Perspective on its Production, Metabolism, and Functions

Slominski, A. T., Hardeland, R., Zmijewski, M. A., Slominski, R. M., Reiter, R. J. & Paus, R., Mar 1 2018, In : Journal of Investigative Dermatology. 138, 3, p. 490-499 10 p.

Research output: Contribution to journalReview article

53 Scopus citations
2019

JAK inhibitors and alopecia areata

Gilhar, A., Keren, A. & Paus, R., Jan 26 2019, In : The Lancet. 393, 10169, p. 318-319 2 p.

Research output: Contribution to journalLetter

12 Scopus citations
2016

Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis

Fleger-Weckmann, A., Üstün, Y., Kloepper, J., Paus, R., Bloch, W., Chen, Z. L., Wegner, J., Sorokin, L., Langbein, L., Eckes, B., Zigrino, P., Krieg, T. & Nischt, R., Dec 1 2016, In : Matrix Biology. 56, p. 42-56 15 p.

Research output: Contribution to journalArticle

9 Scopus citations
2020

Tissue-resident macrophages can be generated de novo in adult human skin from resident progenitor cells during substance P-mediated neurogenic inflammation ex vivo

Gherardini, J., Uchida, Y., Hardman, J. A., Chéret, J., Mace, K., Bertolini, M. & Paus, R., Jan 1 2020, In : PloS one. 15, 1, e0227817.

Research output: Contribution to journalArticle

Open Access
2018

Topically Applied Nicotinamide Inhibits Human Hair Follicle Growth Ex Vivo

Haslam, I. S., Hardman, J. A. & Paus, R., Jun 2018, In : Journal of Investigative Dermatology. 138, 6, p. 1420-1422 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

iNKT cells ameliorate human autoimmunity: Lessons from alopecia areata

Ghraieb, A., Keren, A., Ginzburg, A., Ullmann, Y., Schrum, A. G., Paus, R. & Gilhar, A., Jul 1 2018, In : Journal of Autoimmunity. 91, p. 61-72 12 p.

Research output: Contribution to journalArticle

4 Scopus citations
2019

Thyroxine (T4) may promote re-epithelialisation and angiogenesis in wounded human skin ex vivo

Zhang, G. Y., Langan, E. A., Meier, N. T., Funk, W., Siemers, F. & Paus, R., Mar 1 2019, In : PloS one. 14, 3, e0212659.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

Olfactory receptor OR2AT4 regulates human hair growth

Chéret, J., Bertolini, M., Ponce, L., Lehmann, J., Tsai, T., Alam, M., Hatt, H. & Paus, R., Dec 1 2018, In : Nature Communications. 9, 1, 3624.

Research output: Contribution to journalArticle

12 Scopus citations

Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles

Hawkshaw, N. J., Hardman, J. A., Haslam, I. S., Shahmalak, A., Gilhar, A., Lim, X. & Paus, R., May 8 2018, In : PLoS Biology. 16, 5, e2003705.

Research output: Contribution to journalArticle

17 Scopus citations

Innate lymphoid cells 3 induce psoriasis in xenotransplanted healthy human skin

Keren, A., Shemer, A., Ginzburg, A., Ullmann, Y., Schrum, A. G., Paus, R. & Gilhar, A., Jul 1 2018, In : Journal of Allergy and Clinical Immunology. 142, 1, p. 305-308.e6

Research output: Contribution to journalArticle

10 Scopus citations
2011

Endocannabinoids modulate human epidermal keratinocyte proliferation and survival via the sequential engagement of cannabinoid receptor-1 and transient receptor potential vanilloid-1

Tóth, B. I., Dobrosi, N., Dajnoki, A., Czifra, G., Oláh, A., Szöllsi, A. G., Juhász, I., Sugawara, K., Paus, R. & Bíró, T., May 2011, In : Journal of Investigative Dermatology. 131, 5, p. 1095-1104 10 p.

Research output: Contribution to journalArticle

55 Scopus citations
2015

Toward high-throughput chip calorimetry by use of segmented-flow technology

Wolf, A., Hartmann, T., Bertolini, M., Schemberg, J., Grodrian, A., Lemke, K., Förster, T., Kessler, E., Hänschke, F., Mertens, F., Paus, R. & Lerchner, J., Mar 10 2015, In : Thermochimica Acta. 603, p. 172-183 12 p.

Research output: Contribution to journalArticle

17 Scopus citations
2019

Mineralocorticoid Receptor Antagonists Stimulate Human Hair Growth ex vivo

Hundt, J. E., Sass, S., Funk, W., Bíró, T., Farman, N., Langan, E. A. & Paus, R., Nov 1 2019, In : Skin Pharmacology and Physiology. 32, 6, p. 344-348 5 p.

Research output: Contribution to journalArticle

Fibrosis and stem cell epithelial-mesenchymal transition in primary cicatricial alopecias

Harries, M., Imanishi, H. & Paus, R., Jun 1 2019, In : Journal of the American Academy of Dermatology. 80, 6, p. e165-e166

Research output: Contribution to journalLetter

Open Access
1 Scopus citations
2011

2,4,6-Octatrienoic acid is a novel promoter of melanogenesis and antioxidant defence in normal human melanocytes via PPAR-γ activation

Flori, E., Mastrofrancesco, A., Kovacs, D., Ramot, Y., Briganti, S., Bellei, B., Paus, R. & Picardo, M., Aug 1 2011, In : Pigment Cell and Melanoma Research. 24, 4, p. 618-630 13 p.

Research output: Contribution to journalArticle

33 Scopus citations
2013

Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update

Nakamura, M., Schneider, M. R., Schmidt-Ullrich, R. & Paus, R., Jan 1 2013, In : Journal of dermatological science. 69, 1, p. 6-29 24 p.

Research output: Contribution to journalReview article

31 Scopus citations
2018

Re-investigating the Basement Membrane Zone of Psoriatic Epidermal Lesions: Is Laminin-511 a New Player in Psoriasis Pathogenesis?

Natsumi, A., Sugawara, K., Yasumizu, M., Mizukami, Y., Sano, S., Morita, A., Paus, R. & Tsuruta, D., Jun 1 2018, (Accepted/In press) In : Journal of Histochemistry and Cytochemistry.

Research output: Contribution to journalArticle

2 Scopus citations
2020

Hair(y) Matters in Melanoma Biology

Bedogni, B. & Paus, R., May 2020, In : Trends in Molecular Medicine. 26, 5, p. 441-449 9 p.

Research output: Contribution to journalReview article

2013

Protection against chemotherapy-induced alopecia: Targeting ATP-binding cassette transporters in the hair follicle?

Haslam, I. S., Pitre, A., Schuetz, J. D. & Paus, R., Nov 2013, In : Trends in Pharmacological Sciences. 34, 11, p. 599-604 6 p.

Research output: Contribution to journalReview article

17 Scopus citations
2018

A technique for more precise distinction between catagen and telogen human hair follicles ex vivo

Hernandez, I., Alam, M., Platt, C., Hardman, J., Smart, E., Poblet, E., Bertolini, M., Paus, R. & Jimenez, F., Sep 2018, In : Journal of the American Academy of Dermatology. 79, 3, p. 558-559 2 p.

Research output: Contribution to journalArticle

3 Scopus citations
2017

Site-specific gene expression profiling as a novel strategy for unravelling keloid disease pathobiology

Jumper, N., Hodgkinson, T., Paus, R. & Bayat, A., Mar 1 2017, In : PLoS One. 12, 3, e0172955.

Research output: Contribution to journalArticle

14 Scopus citations
2018

Bridging the "dead hair"-"live follicle" divide in applied hair research

Bertolini, M., Botchkareva, N., Westgate, G., Ward, C., Cornwell, P. & Paus, R., Sep 1 2018, In : Journal of Cosmetic Science. 69, 5, p. 315-322 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2012

Thymic peptides differentially modulate human hair follicle growth

Meier, N., Langan, D., Hilbig, H., Bodó, E., Farjo, N. P., Farjo, B., Armbruster, F. P. & Paus, R., May 2012, In : Journal of Investigative Dermatology. 132, 5, p. 1516-1519 4 p.

Research output: Contribution to journalLetter

6 Scopus citations
2019

Transepidermal UV radiation of scalp skin ex vivo induces hair follicle damage that is alleviated by the topical treatment with caffeine

Gherardini, J., Wegner, J., Chéret, J., Ghatak, S., Lehmann, J., Alam, M., Jimenez, F., Funk, W., Böhm, M., Botchkareva, N. V., Ward, C., Paus, R. & Bertolini, M., Apr 1 2019, In : International journal of cosmetic science. 41, 2, p. 164-182 19 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2018

Delayed Hair Follicle Morphogenesis and Hair Follicle Dystrophy in a Lipoatrophy Mouse Model of Pparg Total Deletion

Sardella, C., Winkler, C., Quignodon, L., Hardman, J. A., Toffoli, B., Giordano Attianese, G. M. P., Hundt, J. E., Michalik, L., Vinson, C. R., Paus, R., Desvergne, B. & Gilardi, F., Mar 1 2018, In : Journal of Investigative Dermatology. 138, 3, p. 500-510 11 p.

Research output: Contribution to journalArticle

15 Scopus citations
2013

Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin.

Meier, N. T., Haslam, I. S., Pattwell, D. M., Zhang, G. Y., Emelianov, V., Paredes, R., Debus, S., Augustin, M., Funk, W., Amaya, E., Kloepper, J. E., Hardman, M. J. & Paus, R., 2013, In : PloS one. 8, 9, e73596.

Research output: Contribution to journalArticle

27 Scopus citations
2014

From frog integument to human skin: Dermatological perspectives from frog skin biology

Haslam, I. S., Roubos, E. W., Mangoni, M. L., Yoshizato, K., Vaudry, H., Kloepper, J. E., Pattwell, D. M., Maderson, P. F. A. & Paus, R., Aug 2014, In : Biological Reviews. 89, 3, p. 618-655 38 p.

Research output: Contribution to journalArticle

23 Scopus citations
2018

Bi-allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis Simplex

Romano, M. T., Tafazzoli, A., Mattern, M., Sivalingam, S., Wolf, S., Rupp, A., Thiele, H., Altmüller, J., Nürnberg, P., Ellwanger, J., Gambon, R., Baumer, A., Kohlschmidt, N., Metze, D., Holdenrieder, S., Paus, R., Lütjohann, D., Frank, J., Geyer, M., Bertolini, M. & 2 others, Kokordelis, P. & Betz, R. C., Nov 1 2018, In : American Journal of Human Genetics. 103, 5, p. 777-785 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Retinoic acid co-treatment aggravates severity of dioxin-induced skin lesions in hairless mice via induction of inflammatory response

Rudyak, S. G., Usakin, L. A., Tverye, E. A., Orekhov, A. S., Belushkina, N. N., Paus, R., Paltsev, M. A. & Panteleyev, A. A., Dec 2 2018, In : Biochemical and biophysical research communications. 506, 4, p. 854-861 8 p.

Research output: Contribution to journalArticle

2012

Thyrotropin-releasing hormone controls mitochondrial biology in human epidermis

Knuever, J., Poeggeler, B., Gáspár, E., Klinger, M., Hellwig-Burgel, T., Hardenbicker, C., Tóth, B. I., Bíró, T. & Paus, R., Mar 1 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 3, p. 978-986 9 p.

Research output: Contribution to journalArticle

22 Scopus citations
2015

Functional histopathology of keloid disease

Jumper, N., Paus, R. & Bayat, A., Jan 1 2015, In : Histology and Histopathology. 30, 9, p. 1033-1057 25 p.

Research output: Contribution to journalReview article

47 Scopus citations
2018

How chemotherapy and radiotherapy damage the tissue: Comparative biology lessons from feather and hair models

Gao, Q. X., Zhou, G. X., Lin, S. J., Paus, R. & Yue, Z. C., Jan 1 2018, (Accepted/In press) In : Experimental Dermatology.

Research output: Contribution to journalArticle

8 Scopus citations
2012

Long-term organ culture of keloid disease tissue

Bagabir, R., Syed, F., Paus, R. & Bayat, A., May 1 2012, In : Experimental dermatology. 21, 5, p. 376-381 6 p.

Research output: Contribution to journalReview article

39 Scopus citations
2011

Can the hair follicle become a model for studying selected aspects of human ocular immune privilege?

Kinori, M., Kloepper, J. E. & Paus, R., Jun 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 7, p. 4447-4458 12 p.

Research output: Contribution to journalArticle

14 Scopus citations