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Author

  • Savita G Pahwa
2011
41 Scopus citations
2019
1 Scopus citations

Current challenges and solutions in research and clinical care of older persons living with HIV: Findings presented at the 9th international workshop on HIV and aging

Sundermann, E. E., Erlandson, K. M., Pope, C. N., Rubtsova, A., Montoya, J., Moore, A. A., Marzolini, C., O'Brien, K. K., Pahwa, S., Payne, B. A. I., Rubin, L. H., Walmsley, S., Haughey, N. J., Montano, M., Karris, M. Y., Margolick, J. B. & Moore, D. J., Nov 1 2019, In : AIDS research and human retroviruses. 35, 11-12, p. 985-998 14 p.

Research output: Contribution to journalArticle

Open Access
2011
53 Scopus citations
2015

HIV infection worsens age-associated defects in antibody responses to influenza vaccine

George, V. K., Pallikkuth, S., Parmigiani, A., Alcaide, M. L., Fischl, M. A., Arheart, K. & Pahwa, S. G., Jun 15 2015, In : Journal of Infectious Diseases. 211, 12, p. 1959-1968 10 p.

Research output: Contribution to journalArticle

27 Scopus citations
2012

Elevated interleukin 8 and T-helper 1 and T-helper 17 cytokine levels prior to antiretroviral therapy in participants who developed immune reconstitution inflammatory syndrome during actg a5164

Grant, P. M., Komarow, L., Lederman, M. M., Pahwa, S. G., Zolopa, A. R., Andersen, J., Asmuth, D. M., Devaraj, S., Pollard, R. B., Richterman, A., Kanthikeel, S. & Sereti, I., Dec 1 2012, In : Journal of Infectious Diseases. 206, 11, p. 1715-1723 9 p.

Research output: Contribution to journalArticle

36 Scopus citations
2018

Cardiac morbidity in HIV infection is associated with checkpoint inhibitor LAG-3 on CD4 T cells

Pallikkuth, S., Pahwa, R., Kausalya, B., Saravanan, S., Pan, L., Vignesh, R., Iqbal, S., Solomon, S. S., Murugavel, K. G., Poongulali, S., Kumarasamy, N. & Pahwa, S. G., Jan 1 2018, In : PLoS One. 13, 10, p. e0206256

Research output: Contribution to journalArticle

2012

Paucity of IL-21-producing CD4+ T cells is associated with Th17 cell depletion in SIV infection of rhesus macaques

Micci, L., Cervasi, B., Ende, Z. S., Iriele, R. I., Reyes-Aviles, E., Vinton, C., Else, J., Silvestri, G., Ansari, A. A., Villinger, F., Pahwa, S. G., Estes, J. D., Brenchley, J. M. & Paiardini, M., Nov 8 2012, In : Blood. 120, 19, p. 3925-3935 11 p.

Research output: Contribution to journalArticle

42 Scopus citations
2017

Lipoprotein(a) and HIV: Allele-specific apolipoprotein(a) levels predict carotid intima-media thickness in hiv-infected young women in the women's interagency HIV study

Enkhmaa, B., Anuurad, E., Zhang, W., Li, C. S., Kaplan, R., Lazar, J., Merenstein, D., Karim, R., Aouizerat, B., Cohen, M., Butler, K., Pahwa, S. G., Ofotokun, I., Adimora, A. A., Golub, E. & Berglund, L., May 1 2017, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 37, 5, p. 997-1004 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
2018

Psychosocial Correlates of Monocyte Activation and HIV Persistence in Methamphetamine Users

Grosgebauer, K., Salinas, J., Sharkey, M. E., Roach, M., Pallikkuth, S., Dilworth, S. E., Pahwa, S. G., Sengul, T., Stevenson, M. & Carrico, A., Jan 1 2018, (Accepted/In press) In : Journal of NeuroImmune Pharmacology.

Research output: Contribution to journalArticle

2 Scopus citations

Effect of antiretroviral therapy on allele-associated Lp(a) level in women with HIV in the Women's Interagency HIV Study

Enkhmaa, B., Anuurad, E., Zhang, W., Li, C. S., Kaplan, R., Lazar, J., Merenstein, D., Karim, R., Aouizerat, B., Cohen, M., Butler, K., Pahwa, S. G., Ofotokun, I., Adimora, A. A., Golub, E. & Berglund, L., Jan 1 2018, In : Journal of Lipid Research. 59, 10, p. 1967-1976 10 p.

Research output: Contribution to journalArticle

4 Scopus citations
2019

Pretransplant Levels of C-Reactive Protein, Soluble TNF Receptor-1, and CD38+HLADR+ CD8 T Cells Predict Risk of Allograft Rejection in HIV+ Kidney Transplant Recipients

Camargo, J. F., Pallikkuth, S., Moroz, I., Natori, Y., Alcaide, M. L., Rodriguez, A., Guerra, G., Burke, G. W. & Pahwa, S., Dec 2019, In : Kidney International Reports. 4, 12, p. 1705-1716 12 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2017

Concomitant nevirapine impacts pharmacokinetic exposure to the antimalarial artemether-lumefantrine in African children

IMPAACT P1079 protocol team, Oct 1 2017, In : PLoS One. 12, 10, e0186589.

Research output: Contribution to journalArticle

4 Scopus citations
2019

HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells

Hyun, J., McMahon, R. S., Lang, A. L., Edwards, J. S., Badilla, A. D., Greene, M. E., Stone, G. W., Pallikkuth, S., Stevenson, M., Dykxhoorn, D. M., Kottilil, S., Pahwa, S. & Thomas, E., Jul 1 2019, In : PLoS pathogens. 15, 7, p. e1007883

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2016

A survey of tuberculosis infection control practices at the NIH/NIAID/DAIDS-supported clinical trial sites in low and middle income countries

HIV Network Coordinating (HANC) TB Diagnostic Laboratory Working Division of AIDS, National Institute of Allergy and Infectious Diseases, Jun 10 2016, In : BMC Infectious Diseases. 16, 1, 269.

Research output: Contribution to journalArticle

5 Scopus citations
2017

Induction of il21 in peripheral t follicular helper cells is an indicator of influenza vaccine response in a previously vaccinated HIV-infected pediatric cohort

De Armas, L. R., Cotugno, N., Pallikkuth, S., Pan, L., Rinaldi, S., Sanchez, M. C., Gonzalez, L., Cagigi, A., Rossi, P., Palma, P. & Pahwa, S. G., Mar 1 2017, In : Journal of Immunology. 198, 5, p. 1995-2005 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Paradoxical aging in HIV: Immune senescence of B Cells is most prominent in young age

Rinaldi, S., Pallikkuth, S., George, V. K., de Armas, L. R., Pahwa, R., Sanchez, C. M., Pallin, M. F., Pan, L., Cotugno, N., Dickinson, G., Rodriguez, A. E., Fischl, M. A., Alcaide, M. L., Gonzalez, L., Palma, P. & Pahwa, S. G., 2017, In : Aging. 9, 4, p. 1307-1325 19 p.

Research output: Contribution to journalArticle

11 Scopus citations
2019

Dysfunctional peripheral T follicular helper cells dominate in people with impaired influenza vaccine responses: Results from the FLORAH study

Pallikkuth, S., De Armas, L. R., Rinaldi, S., George, V. K., Pan, L., Arheart, K. L., Pahwa, R. & Pahwa, S. G., May 1 2019, In : PLoS biology. 17, 5, e3000257.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Single Cell Profiling Reveals PTEN Overexpression in Influenza-Specific B cells in Aging HIV-infected individuals on Anti-retroviral Therapy

de Armas, L. R., Pallikkuth, S., Pan, L., Rinaldi, S., Cotugno, N., Andrews, S., Pahwa, R., McDermott, A. B., Palma, P. & Pahwa, S. G., Dec 1 2019, In : Scientific reports. 9, 1, 2482.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2013

Immune Activation in HIV-Infected Aging Women on Antiretrovirals-Implications for Age-Associated Comorbidities: A Cross-Sectional Pilot Study

Alcaide, M. L., Parmigiani, A., Pallikkuth, S., Roach, M., Freguja, R., Negra, M. D., Bolivar, H., Fischl, M. A. & Pahwa, S., May 28 2013, In : PloS one. 8, 5, e63804.

Research output: Contribution to journalArticle

43 Scopus citations
2017

Associations of Plasma Cytokine and Microbial Translocation Biomarkers With Immune Reconstitution Inflammatory Syndrome

AIDS Clinical Trials Group A5202 Study Team, Nov 27 2017, In : The Journal of infectious diseases. 216, 9, p. 1159-1163 5 p.

Research output: Contribution to journalArticle

5 Scopus citations
2012

The role of interleukin-21 in HIV infection

Pallikkuth, S., Parmigiani, A. & Pahwa, S., Aug 1 2012, In : Cytokine and Growth Factor Reviews. 23, 4-5, p. 173-180 8 p.

Research output: Contribution to journalArticle

13 Scopus citations
2018

Substance-associated elevations in monocyte activation among methamphetamine users with treated HIV infection

Carrico, A., Cherenack, E. M., Roach, M. E., Riley, E. D., Oni, O., DIlworth, S. E., Shoptaw, S., Hunt, P., Roy, S., Pallikkuth, S. & Pahwa, S. G., Mar 27 2018, In : AIDS. 32, 6, p. 767-771 5 p.

Research output: Contribution to journalArticle

6 Scopus citations
2015

Effect of cytomegalovirus co-infection on normalization of selected T-cell subsets in children with perinatally acquired HIV infection treated with combination antiretroviral therapy

Pediatric AIDS Clinical Trials Group Protocol 366, Mar 20 2015, In : PLoS One. 10, 3, e0120474.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Altered immune cell follicular dynamics in HIV infection following influenza vaccination

Moysi, E., Pallikkuth, S., De Armas, L. R., Gonzalez, L. E., Ambrozak, D., George, V., Huddleston, D., Pahwa, R., Koup, R. A., Petrovas, C. & Pahwa, S. G., Jul 2 2018, In : Journal of Clinical Investigation. 128, 7, p. 3171-3185 15 p.

Research output: Contribution to journalArticle

15 Scopus citations

Circulating inflammatory monocytes contribute to impaired influenza vaccine responses in HIV-infected participants

George, V. K., Pallikkuth, S., Pahwa, R., De Armas, L. R., Rinaldi, S., Pan, L. & Pahwa, S. G., Jun 19 2018, In : AIDS. 32, 10, p. 1219-1228 10 p.

Research output: Contribution to journalArticle

4 Scopus citations
2014

Premature B-cell senescence as a consequence of chronic immune activation: Implications for vaccination of immune compromised individuals

Palma, P., Rinaldi, S., Cotugno, N., Santilli, V., Pahwa, S., Rossi, P. & Cagigi, A., Jul 1 2014, In : Human Vaccines and Immunotherapeutics. 10, 7, p. 2083-2088 6 p.

Research output: Contribution to journalReview article

7 Scopus citations
2016
62 Scopus citations
2012

Role of IL-21 and IL-21 receptor on B cells in HIV infection.

Pallikkuth, S., Parmigiani, A. & Pahwa, S., 2012, In : Critical reviews in immunology. 32, 2, p. 173-195 23 p.

Research output: Contribution to journalReview article

19 Scopus citations
2013
43 Scopus citations
15 Scopus citations
2019

A prospective study of the immune reconstitution inflammatory syndrome (IRIS) in HIV-infected children from high prevalence countries

on behalf of the P1073 team, Jan 1 2019, In : PloS one. 14, 7, e0211155.

Research output: Contribution to journalArticle

Open Access
2013

Interleukin-21 and T follicular helper cells in HIV infection: Research focus and future perspectives

Pallikkuth, S. & Pahwa, S., Dec 1 2013, In : Immunologic Research. 57, 1-3, p. 279-291 13 p.

Research output: Contribution to journalArticle

13 Scopus citations
2019

Implications of immune checkpoint expression during aging in HIV-infected people on antiretroviral therapy

De Armas, L. R., Pallikkuth, S., Rinaldi, S., Pahwa, R. & Pahwa, S., Nov 1 2019, In : AIDS research and human retroviruses. 35, 11-12, p. 1112-1122 11 p.

Research output: Contribution to journalArticle

2011

Innate immune defects correlate with failure of antibody responses to H1N1/09 vaccine in HIV-infected patients

Pallikkuth, S., Kanthikeel, S. P., Silva, S. Y., Fischl, M., Pahwa, R. & Pahwa, S., Dec 1 2011, In : Journal of Allergy and Clinical Immunology. 128, 6, p. 1279-1285 7 p.

Research output: Contribution to journalArticle

20 Scopus citations
2013

Defective dendritic cell response to Toll-like receptor 7/8 agonists in perinatally HIV-infected children

Selvaraj, A., Pilakka-Kanthikeel, S., Bhavani, P. K., Hanna, L. E., Pahwa, S. & Swaminathan, S., Dec 2013, In : Pathogens and Disease. 69, 3, p. 184-193 10 p.

Research output: Contribution to journalArticle

7 Scopus citations
2015

Early antiretroviral therapy in children perinatally infected with HIV: A unique opportunity to implement immunotherapeutic approaches to prolong viral remission

Klein, N., Palma, P., Luzuriaga, K., Pahwa, S. G., Nastouli, E., Gibb, D. M., Rojo, P., Borkowsky, W., Bernardi, S., Zangari, P., Calvez, V., Compagnucci, A., Wahren, B., Foster, C., Munoz-Fernández, M. Á., De Rossi, A., Ananworanich, J., Pillay, D., Giaquinto, C. & Rossi, P., Sep 1 2015, In : The Lancet Infectious Diseases. 15, 9, p. 1108-1114 7 p.

Research output: Contribution to journalArticle

23 Scopus citations
2012

Increased gut microbial translocation in HIV-infected children persists in virologic responders and virologic failures after antiretroviral therapy

Pilakka-Kanthikeel, S., Huang, S., Fenton, T., Borkowsky, W., Cunningham, C. K. & Pahwa, S., Jun 1 2012, In : Pediatric Infectious Disease Journal. 31, 6, p. 583-591 9 p.

Research output: Contribution to journalArticle

29 Scopus citations
2017

T follicular helper cells and B cell dysfunction in aging and HIV-1 infection

Pallikkuth, S., de Armas, L., Rinaldi, S. & Pahwa, S. G., Oct 23 2017, In : Frontiers in Immunology. 8, OCT, 1380.

Research output: Contribution to journalShort survey

13 Scopus citations

Immune development in HIV-exposed uninfected children born to HIV-infected women

Miyamoto, M., Gouvêa, A. F. T. B., Ono, E., Succi, R. C. M., Pahwa, S. G. & de Moraes-Pinto, M. I., Feb 28 2017, In : Revista do Instituto de Medicina Tropical de Sao Paulo. 59, e30.

Research output: Contribution to journalArticle

6 Scopus citations
2019

HIV and carotid atherosclerosis: a mediational model

Alcaide, M. L., Rodriguez, V. J., Abbamonte, J. M., Pallikuth, S., Langlie, J., Soni, M., Weiss, S. M., Hurwitz, B. E., Pahwa, S., Jones, D. L. & Kumar, M., Jan 1 2019, (Accepted/In press) In : AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV.

Research output: Contribution to journalArticle

2017
10 Scopus citations
2019

Harvard HIV and aging workshop: Perspectives and Priorities from Claude D. Pepper Centers and Centers for AIDS Research

Montano, M., Bhasin, S., D'Aquila, R. T., Erlandson, K. M., Evans, W. J., Funderburg, N. T., Justice, A., Ndhlovu, L. C., Ojikutu, B., Pahor, M., Pahwa, S., Ryan, A. S., Schrack, J., Schultz, M. B., Sebastiani, P., Sinclair, D. A., Tripp, J., Walker, B., Womack, J. A., Yung, R. & 1 others, Reeves, R. K., Nov 1 2019, In : AIDS research and human retroviruses. 35, 11-12, p. 999-1012 14 p.

Research output: Contribution to journalArticle

Open Access
2018

Microbial Translocation and Immune Activation in HIV-1 Infected Pregnant Women

Mitchell, C. D., Dominguez, S., Roach, M., George, V., Rinaldi, S., Fischl, M. A., Potter, J. E., Tyson, B. & Pahwa, S. G., Jan 1 2018, In : Current HIV Research. 16, 3, p. 208-215 8 p.

Research output: Contribution to journalArticle

Recent stimulant use and leukocyte gene expression in methamphetamine users with treated HIV infection

Carrico, A., Flentje, A., Kober, K., Lee, S., Hunt, P., Riley, E. D., Shoptaw, S., Flowers, E., Dilworth, S. E., Pahwa, S. G. & Aouizerat, B. E., Jan 1 2018, (Accepted/In press) In : Brain, Behavior, and Immunity.

Research output: Contribution to journalArticle

4 Scopus citations

Impact of aging and HIV infection on serologic response to seasonal influenza vaccination

Pallikkuth, S., De Armas, L. R., Pahwa, R., Rinaldi, S., George, V. K., Sanchez, C. M., Pan, L., Dickinson, G., Rodriguez, A. E., Fischl, M. A., Alcaide, M. L. & Pahwa, S. G., Jun 1 2018, In : AIDS. 32, 9, p. 1085-1094 10 p.

Research output: Contribution to journalArticle

7 Scopus citations
2016

A therapeutic HIV-1 vaccine enhances anti-HIV-1 immune responses in patients under highly active antiretroviral therapy

Tung, F. Y., Tung, J. K., Pallikkuth, S., Pahwa, S. G. & Fischl, M. A., Apr 27 2016, In : Vaccine. 34, 19, p. 2225-2232 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2011

Interleukin-21 and cellular activation concurrently induce potent cytotoxic function and promote antiviral activity in human CD8 T cells

Parmigiani, A., Pallin, M. F., Schmidtmayerova, H., Lichtenheld, M. G. & Pahwa, S., Feb 1 2011, In : Human Immunology. 72, 2, p. 115-123 9 p.

Research output: Contribution to journalArticle

31 Scopus citations
2014

Immune activation is associated with increased gut microbial translocation in treatment-naive, HIV-infected children in a resource-limited setting

Pilakka-Kanthikeel, S., Kris, A., Selvaraj, A., Swaminathan, S. & Pahwa, S., May 1 2014, In : Journal of Acquired Immune Deficiency Syndromes. 66, 1, p. 16-24 9 p.

Research output: Contribution to journalArticle

20 Scopus citations
2012

Long-Term Engraftment of Human Natural T Regulatory Cells in NOD/SCID IL2rγcnull Mice by Expression of Human IL-2

Abraham, S., Pahwa, R., Ye, C., Choi, J. G., Pahwa, S., Jaggaiahgari, S., Raut, A., Chen, S., Manjunath, N. & Shankar, P., Dec 18 2012, In : PloS one. 7, 12, e51832.

Research output: Contribution to journalArticle

10 Scopus citations