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  • Jay S Skyler
2020

A Wake-Up Call

Skyler, J. S., Feb 2020, In : Diabetes Technology and Therapeutics. 22, 2, 1 p.

Research output: Contribution to journalComment/debate

2017

The Use of Electrochemiluminescence Assays to Predict Autoantibody and Glycemic Progression Toward Type 1 Diabetes in Individuals with Single Autoantibodies

Sosenko, J. M., Yu, L., Skyler, J. S., Krischer, J. P., Gottlieb, P. A., Boulware, D., Miao, D., Palmer, J. P. & Steck, A. K., Mar 1 2017, In : Diabetes Technology and Therapeutics. 19, 3, p. 183-187 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Hope vs hype: where are we in type 1 diabetes?

Skyler, J. S., Dec 23 2017, (Accepted/In press) In : Diabetologia. p. 1-8 8 p.

Research output: Contribution to journalArticle

12 Scopus citations
2019

Imagining a better future for all people with type 1 diabetes mellitus

Korsgren, O., Skyler, J. S., Skog, O., Sundberg, F., Forsander, G. & Ludvigsson, J., Jan 1 2019, (Accepted/In press) In : Nature Reviews Endocrinology.

Research output: Contribution to journalComment/debate

1 Scopus citations
2012

Type 1 Diabetes Mellitus: Immune Intervention

Skyler, J. S., Mar 1 2012, ATTD 2011 Year Book: Advanced Technologies and Treatments for Diabetes: Third Edition. Wiley Blackwell, p. 157-173 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2015

Type 1 diabetes at a crossroads

Cefalu, W. T., Tamborlane, W. V. & Skyler, J. S., Jun 1 2015, In : Diabetes Care. 38, 6, p. 968-970 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

Effect of ranolazine monotherapy on glycemic control in subjects with type 2 diabetes

Eckel, R. H., Henry, R. R., Yue, P., Dhalla, A., Wong, P., Jochelson, P., Belardinelli, L. & Skyler, J. S., Jul 1 2015, In : Diabetes Care. 38, 7, p. 1189-1196 8 p.

Research output: Contribution to journalArticle

26 Scopus citations
2014

Struggles with clinical translation of immune intervention trials

Skyler, J. S., May 2014, In : Diabetes care. 37, 5, p. 1173-1175 3 p.

Research output: Contribution to journalComment/debate

3 Scopus citations
2015

Subcutaneous injection of hyaluronidase with recombinant human insulin compared with insulin lispro in type 1 diabetes

Garg, S. K., Buse, J. B., Skyler, J. S., Vaughn, D. E. & Muchmore, D. B., Feb 1 2015, In : Diabetes Technology and Therapeutics. 17, p. S45-S46

Research output: Contribution to journalArticle

2013

The compelling case for anti-CD3 in type 1 diabetes

Skyler, J. S., Nov 1 2013, In : Diabetes. 62, 11, p. 3656-3657 2 p.

Research output: Contribution to journalComment/debate

7 Scopus citations
2011

Stopping type 1 diabetes: Attempts to prevent or cure type 1 diabetes in man

Skyler, J. S. & Ricordi, C., Jan 1 2011, In : Diabetes. 60, 1, p. 1-8 8 p.

Research output: Contribution to journalReview article

74 Scopus citations
2014

Characterizing subgroups of type 1 diabetes

Skyler, J. S., Nov 1 2014, In : Diabetes. 63, 11, p. 3578-3580 3 p.

Research output: Contribution to journalComment/debate

4 Scopus citations
2013

Primary and secondary prevention of Type 1 diabetes

Skyler, J. S., Feb 1 2013, In : Diabetic Medicine. 30, 2, p. 161-169 9 p.

Research output: Contribution to journalReview article

53 Scopus citations

George S. Eisenbarth: insulin and type 1 diabetes

Pugliese, A. & Skyler, J. S., Jun 1 2013, In : Diabetes care. 36, 6, p. 1437-1442 6 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

ATG in type 1 diabetes: An unanswered question

Skyler, J. S., Dec 2013, In : The Lancet Diabetes and Endocrinology. 1, 4, p. 265-266 2 p.

Research output: Contribution to journalLetter

Preface

Mccabe, P. M., Schneiderman, N., Field, T. M. & Skyler, J. S., May 13 2013, Stress, Coping, and Disease. Taylor and Francis, p. xi-xv

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

Stress, coping, and disease

Mccabe, P. M., Schneiderman, N., Field, T. M. & Skyler, J. S., May 13 2013, Taylor and Francis. 280 p.

Research output: Book/ReportBook

2018

Sleeping oxygen saturation, rapid eye movement sleep, and the adaptation of postprandial metabolic function in insulin sensitive and resistant individuals without diabetes

Garcia, K. A., Wohlgemuth, W. K., Ferrannini, E., Mari, A., Gonzalez, A., Mendez, A. J., Bizzotto, R., Skyler, J. S., Schneiderman, N. & Hurwitz, B., Jul 1 2018, In : Physiology and Behavior. 191, p. 123-130 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2013

The prediction of type 1 diabetes by multiple autoantibody levels and their incorporation into an autoantibody risk score in relatives of type 1 diabetic patients

Sosenko, J. M., Skyler, J. S., Palmer, J. P., Krischer, J. P., Yu, L., Mahon, J., Beam, C. A., Boulware, D. C., Rafkin, L., Schatz, D. & Eisenbarth, G., Sep 1 2013, In : Diabetes care. 36, 9, p. 2615-2620 6 p.

Research output: Contribution to journalArticle

57 Scopus citations
2018

Insulin sensitivity and blood pressure

Skyler, J. S., Marks, J. B., Thompson, N. E., Fili, M. D. & Schneiderman, N., Jan 1 2018, Stress and Disease Processes: Perspectives in Behavioral Medicine. Taylor and Francis, p. 197-223 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2015

The development and utility of a novel scale that quantifies the glycemic progression toward type 1 diabetes over 6 months

Sosenko, J. M., Skyler, J. S., Beam, C. A., Boulware, D., Mahon, J. L., Krischer, J. P., Greenbaum, C. J., Rafkin, L., Matheson, D., Herold, K. C. & Palmer, J. P., May 1 2015, In : Diabetes Care. 38, 5, p. 940-942 3 p.

Research output: Contribution to journalArticle

8 Scopus citations
2013

Interleukin-1 antagonism in type 1 diabetes of recent onset: Two multicentre, randomised, double-blind, placebo-controlled trials

Moran, A., Bundy, B., Becker, D. J., DiMeglio, L. A., Gitelman, S. E., Goland, R., Greenbaum, C. J., Herold, K. C., Marks, J. B., Raskin, P., Sanda, S., Schatz, D., Wherrett, D. K., Wilson, D. M., Krischer, J. P., Skyler, J. S., Pickersgill, L., De Koning, E., Ziegler, A. G., Böehm, B. & 11 others, Badenhoop, K., Schloot, N., Bak, J. F., Pozzilli, P., Mauricio, D., Donath, M. Y., Castaño, L., Wägner, A., Lervang, H. H., Perrild, H. & Mandrup-Poulsen, T., Jun 1 2013, In : The Lancet. 381, 9881, p. 1905-1915 11 p.

Research output: Contribution to journalArticle

193 Scopus citations
2011

Development of autoantibodies in the TrialNet natural history study

Vehik, K., Beam, C. A., Mahon, J. L., Schatz, D. A., Haller, M. J., Sosenko, J. M., Skyler, J. S. & Krischer, J. P., Sep 1 2011, In : Diabetes care. 34, 9, p. 1897-1901 5 p.

Research output: Contribution to journalArticle

37 Scopus citations
2019

Low-dose anti-thymocyte globulin preserves C-peptide, reduces HbA1c, and increases regulatory to conventional T-cell ratios in new-onset type 1 diabetes: Two-year clinical trial data

Type 1 Diabetes TrialNet ATG-GCSF Study Group, Jun 1 2019, In : Diabetes. 68, 6, p. 1267-1276 10 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2012

Use of continuous glucose monitoring in children and adolescents

Phillip, M., Danne, T., Shalitin, S., Buckingham, B., Laffel, L., Tamborlane, W., Battelino, T., Hanas, R., Chase, P. H., O'Riordan, S., Fisher, L., Skyler, J., Jarosz-Chobot, P., Schober, E., de Beaufort, C., Fox, L. & Kordonouri, O., May 1 2012, In : Pediatric Diabetes. 13, 3, p. 215-228 14 p.

Research output: Contribution to journalArticle

78 Scopus citations
2018

Low-Dose Anti-Thymocyte Globulin (ATG) Preserves β-Cell Function and Improves HbA1c in New-Onset Type 1 Diabetes

Type 1 Diabetes TrialNet ATG-GCSF Study Group, Sep 1 2018, In : Diabetes Care. 41, 9, p. 1917-1925 9 p.

Research output: Contribution to journalArticle

16 Scopus citations
2015

Effect of docosahexaenoic acid supplementation on inflammatory cytokine levels in infants at high genetic risk for type 1 diabetes

The Type 1 Diabetes TrialNet Nutritional Intervention to Prevent (NIP) Type 1 Diabetes Study Group, Jun 1 2015, In : Pediatric Diabetes. 16, 4, p. 271-279 9 p.

Research output: Contribution to journalArticle

18 Scopus citations
2013

An analysis of characteristics of subjects examined for incretin effects on pancreatic pathology

Harja, E., Lord, J. & Skyler, J. S., Aug 1 2013, In : Diabetes Technology and Therapeutics. 15, 8, p. 609-618 10 p.

Research output: Contribution to journalReview article

24 Scopus citations
2012

Prognostic accuracy of immunologic and metabolic markers for type 1 diabetes in a high-risk population receiver operating characteristic analysis

Xu, P., Beam, C. A., Cuthbertson, D., Sosenko, J. M., Skyler, J. S. & Krischer, J. P., Oct 1 2012, In : Diabetes care. 35, 10, p. 1975-1980 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

The application of the diabetes prevention trial-type 1 risk score for identifying a preclinical state of type 1 diabetes

Sosenko, J. M., Skyler, J. S., Mahon, J., Krischer, J. P., Beam, C. A., Boulware, D. C., Greenbaum, C. J., Rafkin, L. E., Cowie, C., Cuthbertson, D. & Palmer, J. P., Jul 1 2012, In : Diabetes care. 35, 7, p. 1552-1555 4 p.

Research output: Contribution to journalArticle

23 Scopus citations
2011

Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: A randomised, double-blind, placebo-controlled trial

Orban, T., Bundy, B., Becker, D. J., DiMeglio, L. A., Gitelman, S. E., Goland, R., Gottlieb, P. A., Greenbaum, C. J., Marks, J. B., Monzavi, R., Moran, A., Raskin, P., Rodriguez, H., Russell, W. E., Schatz, D., Wherrett, D., Wilson, D. M., Krischer, J. P. & Skyler, J. S., Jul 30 2011, In : The Lancet. 378, 9789, p. 412-419 8 p.

Research output: Contribution to journalArticle

317 Scopus citations
2017

Dysglycemia and Index60 as prediagnostic end points for type 1 diabetes prevention trials

Nathan, B. M., Boulware, D., Geyer, S., Atkinson, M. A., Colman, P., Goland, R., Russell, W., Wentworth, J. M., Wilson, D. M., Evans-Molina, C., Wherrett, D., Skyler, J. S., Moran, A. & Sosenko, J. M., Nov 1 2017, In : Diabetes Care. 40, 11, p. 1494-1499 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
2019

Associations of HbA1c with the timing of C-peptide responses during the oral glucose tolerance test at the diagnosis of type 1 diabetes

Type 1 Diabetes Trial Net and Diabetes Prevention Trial-Type-1 (DPT-1) Study Groups, Jun 1 2019, In : Pediatric Diabetes. 20, 4, p. 408-413 6 p.

Research output: Contribution to journalArticle

2011

Immune profiling by multiple gene expression analysis in patients at-risk and with type 1 diabetes

Han, D., Leyva, C. A., Matheson, D., Mineo, D., Messinger, S., Blomberg, B. B., Hernandez, A., Meneghini, L. F., Allende, G., Skyler, J. S., Alejandro, R., Pugliese, A. & Kenyon, N. S., Jun 1 2011, In : Clinical Immunology. 139, 3, p. 290-301 12 p.

Research output: Contribution to journalArticle

17 Scopus citations
2018

The influence of body mass index and age on C-peptide at the diagnosis of type 1 diabetes in children who participated in the diabetes prevention trial-type 1

Sosenko, J. M., Geyer, S., Skyler, J. S., Rafkin, L., Ismail, H. M., Libman, I. M., Liu, Y. F., DiMeglio, L. A., Evans-Molina, C. & Palmer, J. P., May 1 2018, In : Pediatric Diabetes. 19, 3, p. 403-409 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
2013

Diabetes in adolescence: Effects of multifamily group intervention and parent simulation of diabetes

Satin, W., La Greca, A. M., Zigo, M. A. & Skyler, J. S., Jan 1 2013, Family Issues in Pediatric Psychology. Taylor and Francis, p. 197-213 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Psychosocial issues in IDDM: A multivariate framework

La Greca, A. M. & Skyler, J. S., May 13 2013, Stress, Coping, and Disease. Taylor and Francis, p. 169-190 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
2015

Prevention and reversal of type 1 diabetes--past challenges and future opportunities

Skyler, J. S., Jun 1 2015, In : Diabetes Care. 38, 6, p. 997-1007 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

Toward primary prevention of type 1 diabetes

Skyler, J. S., Apr 21 2015, In : JAMA - Journal of the American Medical Association. 313, 15, p. 1520-1521 2 p.

Research output: Contribution to journalArticle

8 Scopus citations
2011

Immune intervention for type 1 diabetes mellitus.

Skyler, J. S., Feb 2011, In : International journal of clinical practice. Supplement. 170, p. 61-70 10 p.

Research output: Contribution to journalReview article

17 Scopus citations
2012

Innate and adaptive immune gene expression profiles as biomarkers in human type 1 diabetes

Han, D., Cai, X., Wen, J., Matheson, D., Skyler, J. S., Kenyon, N. S. & Chen, Z., Nov 1 2012, In : Clinical and Experimental Immunology. 170, 2, p. 131-138 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
2013

Decision-making in diabetes mellitus type 1

Rustad, J. K., Musselman, D. L., Skyler, J. S., Matheson, D., Delamater, A., Kenyon, N. S., Cáceda, R. & Nemeroff, C. B., Sep 5 2013, In : Journal of Neuropsychiatry and Clinical Neurosciences. 25, 1, p. 40-50 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
2011

Sample size requirements for studies of treatment effects on Beta-Cell function in newly diagnosed type 1 diabetes

Lachin, J. M., McGee, P. L., Greenbaum, C. J., Palmer, J., Pescovitz, M. D., Gottlieb, P. & Skyler, J., Nov 10 2011, In : PloS one. 6, 11, e26471.

Research output: Contribution to journalArticle

22 Scopus citations

A longitudinal study of GAD65 and ICA512 autoantibodies during the progression to type 1 diabetes in diabetes prevention trial-type 1 (DPT-1) participants

Sosenko, J. M., Skyler, J. S., Palmer, J. P., Krischer, J. P., Cuthbertson, D., Yu, L., Schatz, D. A., Orban, T. & Eisenbarth, G., Nov 1 2011, In : Diabetes care. 34, 11, p. 2435-2437 3 p.

Research output: Contribution to journalArticle

17 Scopus citations
2012

The metabolic progression to type 1 diabetes as indicated by serial oral glucose tolerance testing in the diabetes prevention trial-type 1

Sosenko, J. M., Skyler, J. S., Herold, K. C. & Palmer, J. P., Jun 1 2012, In : Diabetes. 61, 6, p. 1331-1337 7 p.

Research output: Contribution to journalReview article

30 Scopus citations
2018

Cardiovascular outcomes trials in type 2 diabetes: Where Do We Go From Here? Ref lections From a Diabetes Care Editors' Expert Forum

Cefalu, W. T., Kaul, S., Gerstein, H. C., Holman, R. R., Zinman, B., Skyler, J. S., Green, J. B., Buse, J. B., Inzucchi, S. E., Leiter, L. A., Raz, I., Rosenstock, J. & Riddle, M. C., Jan 1 2018, In : Diabetes Care. 41, 1, p. 14-31 18 p.

Research output: Contribution to journalArticle

115 Scopus citations
2012

Zinc transporter-8 autoantibodies improve prediction of type 1 diabetes in relatives positive for the standard biochemical autoantibodies

Yu, L., Boulware, D. C., Beam, C. A., Hutton, J. C., Wenzlau, J. M., Greenbaum, C. J., Bingley, P. J., Krischer, J. P., Sosenko, J. M., Skyler, J. S., Eisenbarth, G. S. & Mahon, J. L., Jun 1 2012, In : Diabetes care. 35, 6, p. 1213-1218 6 p.

Research output: Contribution to journalArticle

54 Scopus citations
2014

Costimulation modulation with abatacept in patients with recent-onset type 1 diabetes: Follow-up 1 year aftercessation of treatment

Orban, T., Bundy, B., Becker, D. J., DiMeglio, L. A., Gitelman, S. E., Goland, R., Gottlieb, P. A., Greenbaum, C. J., Marks, J. B., Monzavi, R., Moran, A., Peakman, M., Raskin, P., Russell, W. E., Schatz, D., Wherrett, D. K., Wilson, D. M., Krischer, J. P. & Skyler, J. S., Apr 2014, In : Diabetes care. 37, 4, p. 1069-1075 7 p.

Research output: Contribution to journalArticle

82 Scopus citations
2011

Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: A randomised double-blind trial

Wherrett, D. K., Bundy, B., Becker, D. J., Dimeglio, L. A., Gitelman, S. E., Goland, R., Gottlieb, P. A., Greenbaum, C. J., Herold, K. C., Marks, J. B., Monzavi, R., Moran, A., Orban, T., Palmer, J. P., Raskin, P., Rodriguez, H., Schatz, D., Wilson, D. M., Krischer, J. P. & Skyler, J. S., Jan 1 2011, In : The Lancet. 378, 9788, p. 319-327 9 p.

Research output: Contribution to journalArticle

221 Scopus citations
2018

Brief commentary: Confusing treatment guidelines for patients with type 2 diabetes

Hirsch, I. B. & Skyler, J. S., Aug 21 2018, In : Annals of Internal Medicine. 169, 4, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations