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  • Stephen D Nimer
2013

MDS stem cell biology

Greenblatt, S. M., Deeg, H. J. & Nimer, S. D., Jan 1 2013, Myelodysplastic Syndromes, Second Edition. Springer Berlin Heidelberg, p. 73-84 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

Histone-binding of DPF2 mediates its repressive role in myeloid differentiation

Huber, F. M., Greenblatt, S. M., Davenport, A. M., Martinez, C., Xu, Y., Vu, L. P., Nimer, S. D. & Hoelz, A., Jun 6 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 23, p. 6016-6021 6 p.

Research output: Contribution to journalArticle

7 Scopus citations
2011

An Update on the Molecular Pathogenesis of Myelodysplastic Syndromes

Nimer, S. D., Jan 2011, In : Biology of Blood and Marrow Transplantation. 17, 1 SUPPL, p. S11-S14

Research output: Contribution to journalArticle

1 Scopus citations
2015

The role of histone acetyltransferases in normal and malignant hematopoiesis

Sun, X. J., Man, N., Tan, Y., Nimer, S. D. & Wang, L., 2015, In : Frontiers in Oncology. 5, MAY, 108.

Research output: Contribution to journalArticle

36 Scopus citations

Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice

Zhao, Z., Chen, L., Dawlaty, M. M., Pan, F., Weeks, O., Zhou, Y., Cao, Z., Shi, H., Wang, J., Lin, L., Chen, S., Yuan, W., Qin, Z., Ni, H., Nimer, S. D., Yang, F-C., Jaenisch, R., Jin, P. & Xu, M., Nov 24 2015, In : Cell Reports. 13, 8, p. 1692-1704 13 p.

Research output: Contribution to journalArticle

47 Scopus citations
2011

L3MBTL1 deficiency directs the differentiation of human embryonic stem cells toward trophectoderm.

Hoya-Arias, R., Tomishima, M., Perna, F., Voza, F. & Nimer, S. D., Nov 2011, In : Stem cells and development. 20, 11, p. 1889-1900 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Nuclear JAK2

Dawson, M. A., Bannister, A. J., Saunders, L., Wahab, O. A., Liu, F., Nimer, S. D., Levine, R. L., Göttgens, B., Kouzarides, T. & Green, A. R., Dec 22 2011, In : Blood. 118, 26, p. 6987-6988 2 p.

Research output: Contribution to journalLetter

5 Scopus citations
2012

Loss of p53 accelerates the complications of myelodysplastic syndrome in a NUP98-HOXD13-driven mouse model

Xu, H., Menendez, S., Schlegelberger, B., Bae, N., Aplan, P. D., Göhring, G., Deblasio, T. R. & Nimer, S. D., Oct 11 2012, In : Blood. 120, 15, p. 3089-3097 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

MEF promotes stemness in the pathogenesis of gliomas

Bazzoli, E., Pulvirenti, T., Oberstadt, M. C., Perna, F., Wee, B., Schultz, N., Huse, J. T., Fomchenko, E. I., Voza, F., Tabar, V., Brennan, C. W., Deangelis, L. M., Nimer, S. D., Holland, E. C. & Squatrito, M., Dec 7 2012, In : Cell Stem Cell. 11, 6, p. 836-844 9 p.

Research output: Contribution to journalArticle

26 Scopus citations
2013

PI3K-Akt pathway regulates polycomb group protein and stem cell maintenance

Liu, Y., Yu, H. & Nimer, S. D., Jan 1 2013, In : Cell Cycle. 12, 2, p. 199-200 2 p.

Research output: Contribution to journalEditorial

4 Scopus citations
2015

Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia

Shih, A. H., Jiang, Y., Meydan, C., Shank, K., Pandey, S., Barreyro, L., Antony-Debre, I., Viale, A., Socci, N., Sun, Y., Robertson, A., Cavatore, M., deStanchina, E., Hricik, T., Rapaport, F., Woods, B., Wei, C., Hatlen, M., Baljevic, M., Nimer, S. D. & 8 others, Tallman, M., Paietta, E., Cimmino, L., Aifantis, I., Steidl, U., Mason, C., Melnick, A. & Levine, R. L., Apr 13 2015, In : Cancer Cell. 27, 4, p. 502-515 14 p.

Research output: Contribution to journalArticle

106 Scopus citations
2016

DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling

Guryanova, O. A., Shank, K., Spitzer, B., Luciani, L., Koche, R. P., Garrett-Bakelman, F. E., Ganzel, C., Durham, B. H., Mohanty, A., Hoermann, G., Rivera, S. A., Chramiec, A. G., Pronier, E., Bastian, L., Keller, M. D., Tovbin, D., Loizou, E., Weinstein, A. R., Gonzalez, A. R., Lieu, Y. K. & 19 others, Rowe, J. M., Pastore, F., McKenney, A. S., Krivtsov, A. V., Sperr, W. R., Cross, J. R., Mason, C. E., Tallman, M. S., Arcila, M. E., Abdel-Wahab, O., Armstrong, S. A., Kubicek, S., Staber, P. B., Gönen, M., Paietta, E. M., Melnick, A. M., Nimer, S. D., Mukherjee, S. & Levine, R. L., Dec 1 2016, In : Nature Medicine. 22, 12, p. 1488-1495 8 p.

Research output: Contribution to journalArticle

68 Scopus citations
2018

Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine (5hmC)

Chu, Y., Zhao, Z., Sant, D. W., Zhu, G., Greenblatt, S. M., Liu, L., Wang, J., Cao, Z., Tho, J. C., Chen, S., Liu, X., Zhang, P., Maciejewski, J. P., Nimer, S. D., Wang, G., Yuan, W., Yang, F-C. & Xu, M., Jan 1 2018, (Accepted/In press) In : Genomics, Proteomics and Bioinformatics.

Research output: Contribution to journalArticle

5 Scopus citations
2011

Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90

Moulick, K., Ahn, J. H., Zong, H., Rodina, A., Cerchietti, L., Gomes DaGama, E. M., Caldas-Lopes, E., Beebe, K., Perna, F., Hatzi, K., Vu, L. P., Zhao, X., Zatorska, D., Taldone, T., Smith-Jones, P., Alpaugh, M., Gross, S. S., Pillarsetty, N., Ku, T., Lewis, J. S. & 8 others, Larson, S. M., Levine, R., Erdjument-Bromage, H., Guzman, M. L., Nimer, S. D., Melnick, A., Neckers, L. & Chiosis, G., Nov 2011, In : Nature Chemical Biology. 7, 11, p. 818-826 9 p.

Research output: Contribution to journalArticle

174 Scopus citations

Myelodysplastic syndromes

Greenberg, P. L., Attar, E., Bennett, J. M., Bloomfield, C. D., De Castro, C. M., Deeg, H. J., Foran, J. M., Gaensler, K., Garcia-Manero, G., Gore, S. D., Head, D., Komrokji, R., Maness, L. J., Millenson, M., Nimer, S. D., O'Donnell, M. R., Schroeder, M. A., Shami, P. J., Stone, R. M., Thompson, J. E. & 1 others, Westervelt, P., Jan 1 2011, In : JNCCN Journal of the National Comprehensive Cancer Network. 9, 1, p. 30-56 27 p.

Research output: Contribution to journalReview article

Open Access
140 Scopus citations
2015

Erratum: Extended survival and reduced risk of AML progression in erythroid-responsive lenalidomide-treated patients with lower-risk del(5q) MDS (Leukemia (2014) 29 (1033-1040) DOI: 10.1038/leu.2013.305)

List, A. F., Bennett, J. M., Sekeres, M. A., Skikne, B., Fu, T., Shammo, J. M., Nimer, S. D., Knight, R. D. & Giagounidis, A., Dec 1 2015, In : Leukemia. 29, 12, p. 2452 1 p.

Research output: Contribution to journalArticle

1 Scopus citations
2012

Bortezomib, liposomal doxorubicin and dexamethasone followed by thalidomide and dexamethasone is an effective treatment for patients with newly diagnosed multiple myeloma with Internatinal Staging System stage II or III, or extramedullary disease

Landau, H., Pandit-Taskar, N., Hassoun, H., Cohen, A., Lesokhin, A., Lendvai, N., Drullinsky, P., Schulman, P., Jhanwar, S., Hoover, E., Bello, C., Riedel, E., Nimer, S. D. & Comenzo, R. L., Feb 1 2012, In : Leukemia and Lymphoma. 53, 2, p. 275-281 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

The checkpoint kinase inhibitor AZD7762 potentiates chemotherapy-induced apoptosis of p53-mutated multiple myeloma cells

Landau, H. J., McNeely, S. C., Nair, J. S., Comenzo, R. L., Asai, T., Friedman, H., Jhanwar, S. C., Nimer, S. D. & Schwartz, G. K., Aug 1 2012, In : Molecular cancer therapeutics. 11, 8, p. 1781-1788 8 p.

Research output: Contribution to journalArticle

34 Scopus citations
2011

Consolidation with bortezomib and dexamethasone following risk-adapted melphalan and stem cell transplant in systemic AL amyloidosis

Landau, H., Hassoun, H., Bello, C., Hoover, E., Riedel, E. R., Nimer, S. D. & Comenzo, R. L., Jun 1 2011, In : Amyloid. 18, SUPPL. 1, p. 135-136 2 p.

Research output: Contribution to journalArticle

18 Scopus citations
2019

Destabilization of AETFC through C/EBPα-mediated repression of LYL1 contributes to t(8;21) leukemic cell differentiation

Zhang, M. M., Liu, N., Zhang, Y. L., Rong, B., Wang, X. L., Xu, C. H., Xie, Y. Y., Shen, S., Zhu, J., Nimer, S. D., Chen, Z., Chen, S. J., Roeder, R. G., Lan, F., Wang, L., Huang, Q. H. & Sun, X. J., Jan 1 2019, In : Leukemia.

Research output: Contribution to journalLetter

2018

PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival

Lu, X., Fernando, T. M., Lossos, C., Yusufova, N., Liu, F., Fontán, L., Durant, M., Geng, H., Melnick, J., Luo, Y., Vega, F., Moy, V. T., Inghirami, G., Nimer, S. D., Melnick, A. M. & Lossos, I., Nov 8 2018, In : Blood. 132, 19, p. 2026-2039 14 p.

Research output: Contribution to journalArticle

10 Scopus citations

Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy

Zhang, P., He, F., Bai, J., Yamamoto, S., Chen, S., Zhang, L., Sheng, M., Zhang, L., Guo, Y., Man, N., Yang, H., Wang, S., Cheng, T., Nimer, S. D., Zhou, Y., Xu, M., Wang, Q. F. & Yang, F-C., Dec 3 2018, In : Journal of Clinical Investigation. 128, 12, p. 5383-5398 16 p.

Research output: Contribution to journalArticle

5 Scopus citations
2012

ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression

Abdel-Wahab, O., Adli, M., LaFave, L. M., Gao, J., Hricik, T., Shih, A. H., Pandey, S., Patel, J. P., Chung, Y. R., Koche, R., Perna, F., Zhao, X., Taylor, J. E., Park, C. Y., Carroll, M., Melnick, A., Nimer, S. D., Jaffe, J. D., Aifantis, I., Bernstein, B. E. & 1 others, Levine, R. L., Aug 14 2012, In : Cancer Cell. 22, 2, p. 180-193 14 p.

Research output: Contribution to journalArticle

303 Scopus citations

An Inv(16)(p13.3q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein Defines an Aggressive Subtype of Pediatric Acute Megakaryoblastic Leukemia

Gruber, T. A., Larson Gedman, A., Zhang, J., Koss, C. S., Marada, S., Ta, H. Q., Chen, S. C., Su, X., Ogden, S. K., Dang, J., Wu, G., Gupta, V., Andersson, A. K., Pounds, S., Shi, L., Easton, J., Barbato, M. I., Mulder, H. L., Manne, J., Wang, J. & 29 others, Rusch, M., Ranade, S., Ganti, R., Parker, M., Ma, J., Radtke, I., Ding, L., Cazzaniga, G., Biondi, A., Kornblau, S. M., Ravandi, F., Kantarjian, H., Nimer, S. D., Döhner, K., Döhner, H., Ley, T. J., Ballerini, P., Shurtleff, S., Tomizawa, D., Adachi, S., Hayashi, Y., Tawa, A., Shih, L. Y., Liang, D. C., Rubnitz, J. E., Pui, C. H., Mardis, E. R., Wilson, R. K. & Downing, J. R., Nov 13 2012, In : Cancer Cell. 22, 5, p. 683-697 15 p.

Research output: Contribution to journalArticle

121 Scopus citations
2018

PRMT5 Regulates DNA Repair by Controlling the Alternative Splicing of Histone-Modifying Enzymes

Hamard, P. J., Santiago, G. E., Liu, F., Karl, D. L., Martinez, C., Man, N., Mookhtiar, A. K., Duffort, S., Greenblatt, S., Verdun, R. E. & Nimer, S. D., Sep 4 2018, In : Cell Reports. 24, 10, p. 2643-2657 15 p.

Research output: Contribution to journalArticle

20 Scopus citations
2012

Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy

Koppikar, P., Bhagwat, N., Kilpivaara, O., Manshouri, T., Adli, M., Hricik, T., Liu, F., Saunders, L. M., Mullally, A., Abdel-Wahab, O., Leung, L., Weinstein, A., Marubayashi, S., Goel, A., Gonen, M., Estrov, Z., Ebert, B. L., Chiosis, G., Nimer, S. D., Bernstein, B. E. & 2 others, Verstovsek, S. & Levine, R. L., Sep 6 2012, In : Nature. 489, 7414, p. 155-159 5 p.

Research output: Contribution to journalArticle

204 Scopus citations
2016

Beyond transcription factors: How oncogenic signalling reshapes the epigenetic landscape

Liu, F., Wang, L., Perna, F. & Nimer, S. D., May 25 2016, In : Nature Reviews Cancer. 16, 6, p. 359-372 14 p.

Research output: Contribution to journalReview article

55 Scopus citations
2015

Loss of RUNX1/AML1 arginine-methylation impairs peripheral T cell homeostasis

Mizutani, S., Yoshida, T., Zhao, X., Nimer, S. D., Taniwaki, M. & Okuda, T., Sep 1 2015, In : British Journal of Haematology. 170, 6, p. 859-873 15 p.

Research output: Contribution to journalArticle

5 Scopus citations
2016

Integrative genetic analysis of mouse and human AML identifies cooperating disease alleles

Hatlen, M. A., Arora, K., Vacic, V., Grabowska, E. A., Liao, W., Riley-Gillis, B., Oschwald, D. M., Wang, L., Joergens, J. E., Shih, A. H., Rapaport, F., Gu, S., Voza, F., Asai, T., Neel, B. G., Kharas, M. G., Gonen, M., Levine, R. L. & Nimer, S. D., 2016, In : Journal of Experimental Medicine. 213, 1, p. 25-34 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

MSI2 is required for maintaining activated myelodysplastic syndrome stem cells

Taggart, J., Ho, T. C., Amin, E., Xu, H., Barlowe, T. S., Perez, A. R., Durham, B. H., Tivnan, P., Okabe, R., Chow, A., Vu, L., Park, S. M., Prieto, C., Famulare, C., Patel, M., Lengner, C. J., Verma, A., Roboz, G., Guzman, M., Klimek, V. M. & 4 others, Abdel-Wahab, O., Leslie, C., Nimer, S. D. & Kharas, M. G., Feb 22 2016, In : Nature Communications. 7, 10739.

Research output: Contribution to journalArticle

14 Scopus citations
2015

The polycomb group protein L3MBTL1 repreßes a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells

Perna, F., Vu, L. P., Themeli, M., Kriks, S., Hoya-Arias, R., Khanin, R., Hricik, T., Mansilla-Soto, J., Papapetrou, E. P., Levine, R. L., Studer, L., Sadelain, M. & Nimer, S. D., 2015, In : Stem Cell Reports. 4, 4, p. 658-669 12 p.

Research output: Contribution to journalArticle

3 Scopus citations
2016

Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity

Shirakawa, K., Wang, L., Man, N., Maksimoska, J., Sorum, A. W., Lim, H. W., Lee, I. S., Shimazu, T., Newman, J. C., Schröder, S., Ott, M., Marmorstein, R., Meier, J., Nimer, S. D. & Verdin, E., May 31 2016, In : eLife. 5, MAY2016, e11156.

Research output: Contribution to journalArticle

29 Scopus citations
2015

PARP inhibitors: A treatment option for AML?

Wang, L., Hamard, P. J. & Nimer, S. D., Dec 8 2015, In : Nature Medicine. 21, 12, p. 1393-1394 2 p.

Research output: Contribution to journalArticle

6 Scopus citations
2018

Recent advances in the understanding and treatment of acute myeloid leukemia

Watts, J. & Nimer, S. D., Jan 1 2018, In : F1000Research. 7, 1196.

Research output: Contribution to journalReview article

11 Scopus citations
2017

Loss of p300 accelerates MDS-associated leukemogenesis

Cheng, G., Liu, F., Asai, T., Lai, F., Man, N., Xu, H., Chen, S., Greenblatt, S., Hamard, P. J., Ando, K., Chen, X., Wang, L., Martinez, C., Tadi, M., Wang, L., Xu, M., Yang, F. C., Shiekhattar, R. & Nimer, S. D., Jan 6 2017, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

11 Scopus citations
2014

Chromatin modifiers and the promise of epigenetic therapy in acute leukemia

Greenblatt, S. M. & Nimer, S. D., Jul 2014, In : Leukemia. 28, 7, p. 1396-1406 11 p.

Research output: Contribution to journalReview article

50 Scopus citations
2012

AML1-ETO driven acute leukemia: Insights into pathogenesis and potential therapeutic approaches

Hatlen, M. A., Wang, L. & Nimer, S. D., Sep 1 2012, In : Frontiers of Medicine in China. 6, 3, p. 248-262 15 p.

Research output: Contribution to journalReview article

48 Scopus citations
2018

CTCF boundary remodels chromatin domain and drives aberrant HOX gene transcription in acute myeloid leukemia

Luo, H., Wang, F., Zha, J., Li, H., Yan, B., Du, Q., Yang, F., Sobh, A., Vulpe, C., Drusbosky, L., Cogle, C., Chepelev, I., Xu, B., Nimer, S. D., Licht, J., Qiu, Y., Chen, B., Xu, M. & Huang, S., Aug 23 2018, In : Blood. 132, 8, p. 837-848 12 p.

Research output: Contribution to journalArticle

10 Scopus citations
2017

Multicenter phase II study of temozolomide and myeloablative chemotherapy with autologous stem cell transplant for newly diagnosed anaplastic oligodendroglioma

Thomas, A. A., Abrey, L. E., Terziev, R., Raizer, J., Martinez, N. L., Forsyth, P., Paleologos, N., Matasar, M., Sauter, C. S., Moskowitz, C., Nimer, S. D., Deangelis, L. M., Kaley, T., Grimm, S., Louis, D. N., Cairncross, J. G., Panageas, K. S., Briggs, S., Faivre, G., Mohile, N. A. & 8 others, Mehta, J., Jonsson, P., Chakravarty, D., Gao, J., Schultz, N., Brennan, C. W., Huse, J. T. & Omuro, A., Oct 1 2017, In : Neuro-Oncology. 19, 10, p. 1380-1390 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2012

Necdin, a p53 target gene, regulates the quiescence and response to genotoxic stress of hematopoietic stem/progenitor cells

Asai, T., Liu, Y., Di Giandomenico, S., Bae, N., Ndiaye-Lobry, D., Deblasio, A., Menendez, S., Antipin, Y., Reva, B., Wevrick, R. & Nimer, S. D., Aug 23 2012, In : Blood. 120, 8, p. 1601-1612 12 p.

Research output: Contribution to journalArticle

33 Scopus citations
2018

CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis

Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., Bilbao, D., Stathais, V., McGrew-Jermacowicz, A., Duffort, S., Tadi, M., Blumenthal, E., Newman, S., Vu, L., Xu, Y., Liu, F., Schuerer, S. C., McCabe, M. T., Kruger, R. G., Xu, M. & 5 others, Yang, F-C., Tenen, D., Watts, J., Vega, F. & Nimer, S. D., Jun 11 2018, In : Cancer Cell. 33, 6, p. 1111-1127.e5

Research output: Contribution to journalArticle

7 Scopus citations
2011

The p53 tumor suppressor protein regulates hematopoietic stem cell fate

Asai, T., Liu, Y., Bae, N. & Nimer, S. D., Sep 1 2011, In : Journal of Cellular Physiology. 226, 9, p. 2215-2221 7 p.

Research output: Contribution to journalShort survey

52 Scopus citations
2018

Erratum: CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis (Cancer Cell (2018) 33(6) (1111–1127.e5), (S1535610818302216) (10.1016/j.ccell.2018.05.007))

Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., Bilbao, D., Stathias, V., McGrew-Jermacowicz, A., Duffort, S., Tadi, M., Blumenthal, E., Newman, S., Vu, L., Xu, Y., Liu, F., Schurer, S. C., McCabe, M. T., Kruger, R. G., Xu, M. & 5 others, Yang, F. C., Tenen, D., Watts, J., Vega, F. & Nimer, S. D., Nov 12 2018, In : Cancer Cell. 34, 5, 1 p.

Research output: Contribution to journalComment/debate

2017

Caspase-3 controls AML1-ETO-driven leukemogenesis via autophagy modulation in a ULK1-dependent manner

Man, N., Tan, Y., Sun, X. J., Liu, F., Cheng, G., Greenblatt, S. M., Martinez, C., Karl, D. L., Ando, K., Sun, M., Hou, D., Chen, B., Xu, M., Yang, F-C., Chen, Z., Chen, S., Nimer, S. D. & Wang, L., May 18 2017, In : Blood. 129, 20, p. 2782-2792 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2019

TAF1 plays a critical role in AML1-ETO driven leukemogenesis

Xu, Y., Man, N., Karl, D., Martinez, C., Liu, F., Sun, J., Martinez, C. J., Martin, G. M., Beckedorff, F., Lai, F., Yue, J., Roisman, A., Greenblatt, S., Duffort, S., Wang, L., Sun, X., Figueroa, M., Shiekhattar, R. & Nimer, S., Dec 1 2019, In : Nature communications. 10, 1, 4925.

Research output: Contribution to journalArticle

Open Access
2013

Administration of ATRA to newly diagnosed patients with acute promyelocytic leukemia is delayed contributing to early hemorrhagic death

Altman, J. K., Rademaker, A., Cull, E., Weitner, B. B., Ofran, Y., Rosenblat, T. L., Haidau, A., Park, J. H., Ram, S. L., Orsini, J. M., Sandhu, S., Catchatourian, R., Trifilio, S. M., Adel, N. G., Frankfurt, O., Stein, E. M., Mallios, G., Deblasio, T., Jurcic, J. G., Nimer, S. & 5 others, Peterson, L. A. C., Kwaan, H. C., Rowe, J. M., Douer, D. & Tallman, M. S., Sep 1 2013, In : Leukemia Research. 37, 9, p. 1004-1009 6 p.

Research output: Contribution to journalArticle

51 Scopus citations
2018

Genetic deletion or small-molecule inhibition of the arginine methyltransferase PRMT5 exhibit anti-tumoral activity in mouse models of MLL-rearranged AML

Kaushik, S., Liu, F., Veazey, K. J., Gao, G., Das, P., Neves, L. F., Lin, K., Zhong, Y., Lu, Y., Giuliani, V., Bedford, M. T., Nimer, S. D. & Santos, M. A., Feb 1 2018, In : Leukemia. 32, 2, p. 499-509 11 p.

Research output: Contribution to journalArticle

29 Scopus citations
2016

Generation of a novel, multi-stage, progressive, and transplantable model of plasma cell neoplasms

Asai, T., Hatlen, M. A., Lossos, C., Ndiaye-Lobry, D., Deblasio, A., Murata, K., Fleisher, M., Cortizas, E. M., Verdun, R. E., Petrini, J. & Nimer, S. D., Mar 10 2016, In : Scientific Reports. 6, 22760.

Research output: Contribution to journalArticle

3 Scopus citations
2018

Pathobiological pseudohypoxia as a putative mechanism underlying myelodysplastic syndromes

Hayashi, Y., Zhang, Y., Yokota, A., Yan, X., Liu, J., Choi, K., Li, B., Sashida, G., Peng, Y., Xu, Z., Huang, R., Zhang, L., Freudiger, G. M., Wang, J., Dong, Y., Zhou, Y., Wang, J., Wu, L., Bu, J., Chen, A. & 21 others, Zhao, X., Sun, X., Chetal, K., Olsson, A., Watanabe, M., Romick-Rosendale, L. E., Harada, H., Shih, L. Y., Tse, W., Bridges, J. P., Caligiuri, M. A., Huang, T., Zheng, Y., Witte, D. P., Wang, Q. F., Qu, C. K., Salomonis, N., Grimes, H. L., Nimer, S. D., Xiao, Z. & Huang, G., Nov 1 2018, In : Cancer Discovery. 8, 11, p. 1438-1457 20 p.

Research output: Contribution to journalArticle

6 Scopus citations
2011

Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation

Moran-Crusio, K., Reavie, L., Shih, A., Abdel-Wahab, O., Ndiaye-Lobry, D., Lobry, C., Figueroa, M. E., Vasanthakumar, A., Patel, J., Zhao, X., Perna, F., Pandey, S., Madzo, J., Song, C., Dai, Q., He, C., Ibrahim, S., Beran, M., Zavadil, J., Nimer, S. D. & 4 others, Melnick, A., Godley, L. A., Aifantis, I. & Levine, R. L., Jul 12 2011, In : Cancer Cell. 20, 1, p. 11-24 14 p.

Research output: Contribution to journalArticle

652 Scopus citations