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• 2015

  Triptolide abrogates growth of colon cancer and induces cell cycle arrest by inhibiting transcriptional activation of E2F

  Oliveira, A. R., Beyer, G., Chugh, R., Skube, S. J., Majumder, K., Banerjee, S., Sangwan, V., Li, L., Dawra, R. K., Subramanian, S., Saluja, A. K. & Dudeja, V., Jun 28 2015, In: Laboratory Investigation. 95, 6, p. 648-659 12 p.

  Research output: Contribution to journal › Article › peer-review

  • triptolide
  • Cell Cycle Checkpoints
  • 14-O-phosphonooxymethyltriptolide
  • Colonic Neoplasms
  • Transcriptional Activation
  34 Scopus citations
• 2014

  Endoplasmic reticulum stress is chronically activated in chronic pancreatitis

  Sah, R. P., Garg, S. K., Dixit, A. K., Dudeja, V., Dawra, R. K. & Saluja, A. K., Oct 3 2014, In: Journal of Biological Chemistry. 289, 40, p. 27551-27561 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Endoplasmic Reticulum Stress
  • Chronic Pancreatitis
  • Trypsinogen
  • Chemical activation
  • Pancreatitis
  45 Scopus citations
• 2013

  Triptolide-mediated cell death in neuroblastoma occurs by both apoptosis and autophagy pathways and results in inhibition of nuclear factor-kappa B activity

  Krosch, T. C. K., Sangwan, V., Banerjee, S., Mujumdar, N., Dudeja, V., Saluja, A. K. & Vickers, S. M., Apr 1 2013, In: American journal of surgery. 205, 4, p. 387-396 10 p.

  Research output: Contribution to journal › Article › peer-review

  • triptolide
  • NF-kappa B
  • Neuroblastoma
  • Autophagy
  • Cell Death
  38 Scopus citations
• 2019

  Correction to: Pre-clinical evaluation of Minnelide as a therapy for acute myeloid leukemia (Journal of Translational Medicine (2019) 17 (163 ) DOI: 10.1186/s12967-019-1901-8)

  Giri, B., Gupta, V. K., Yaffe, B., Modi, S., Roy, P., Sethi, V., Lavania, S. P., Vickers, S. M., Dudeja, V., Banerjee, S., Watts, J. & Saluja, A., Sep 4 2019, In: Journal of translational medicine. 17, 1, 301.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • 14-O-phosphonooxymethyltriptolide
  • Translational Medical Research
  • Medicine
  • Acute Myeloid Leukemia
  • Publications
• 2018

  NFκB-mediated invasiveness in CD133⁺ pancreatic TICs is regulated by autocrine and paracrine activation of IL1 signaling

  Nomura, A., Gupta, V. K., Dauer, P., Sharma, N. S., Dudeja, V., Merchant, N., Saluja, A. K. & Banerjee, S., Jan 2018, In: Molecular Cancer Research. 16, 1, p. 162-172 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Neoplastic Stem Cells
  • Autocrine Communication
  • Epithelial-Mesenchymal Transition
  • Up-Regulation
  • Macrophages
  18 Scopus citations
• 2013

  Total pancreatectomy with islet autotransplantation in patients with malignancy: Are we there yet?

  Dudeja, V., Beilman, G. J. & Vickers, S. M., Aug 1 2013, In: Annals of surgery. 258, 2, p. 219-220 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  16 Scopus citations
• 2018

  Long-term Quality of Life and Gastrointestinal Functional Outcomes After Pancreaticoduodenectomy

  Allen, C. J., Yakoub, D., Macedo, F. I., Dosch, A. R., Brosch, J., Dudeja, V., Ayala, R. & Merchant, N. B., Oct 1 2018, In: Annals of surgery. 268, 4, p. 657-664 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreaticoduodenectomy
  • Quality of Life
  • Self-Help Groups
  • Survivors
  • Population
  6 Scopus citations
• 2015

  Primary and liver metastasis-derived cell lines from Kras G12D; Trp53 R172H; Pdx-1 cre animals undergo apoptosis in response to triptolide

  Sangwan, V., Banerjee, S., Jensen, K. M., Chen, Z., Chugh, R., Dudeja, V., Vickers, S. M. & Saluja, A. K., May 25 2015, In: Pancreas. 44, 4, p. 583-589 7 p.

  Research output: Contribution to journal › Article › peer-review

  • triptolide
  • Pancreatic Neoplasms
  • Neoplasm Metastasis
  • Apoptosis
  • Cell Line
  16 Scopus citations
• 2016

  Mutational and transcriptome based sub-classification of pancreatic cancer: Are we there yet?

  Sethi, V., Garg, B., Saluja, A. & Dudeja, V., Jan 1 2016, In: Translational Cancer Research. 5, p. S395-S399

  Research output: Contribution to journal › Editorial › peer-review
• 2011

  Prosurvival role of heat shock factor 1 in the pathogenesis of pancreatobiliary tumors

  Dudeja, V., Chugh, R. K., Sangwan, V., Skube, S. J., Mujumdar, N. R., Antonoff, M. B., Dawra, R. K., Vickers, S. M. & Saluja, A. K., Jun 2011, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 300, 6, p. G948-G955

  Research output: Contribution to journal › Article › peer-review

  • Heat-Shock Response
  • Neoplasms
  • Down-Regulation
  • Caspase 3
  • Small Interfering RNA
  42 Scopus citations
• 2016

  Chapter 60 - Cystic neoplasms of the pancreas: Epidemiology, clinical features, assessment, and management

  Dudeja, V. & Allen, P. J., Dec 2 2016, Blumgart's Surgery of the Liver, Biliary Tract and Pancreas: Sixth Edition. Elsevier Inc., Vol. 1-2. p. 958-970.e2

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Impaired synthesis of stromal components in response to minnelide improves vascular function, drug delivery, and survival in pancreatic cancer

  Banerjee, S., Modi, S., McGinn, O., Zhao, X., Dudeja, V., Ramakrishnan, S. & Saluja, A. K., Jan 15 2016, In: Clinical Cancer Research. 22, 2, p. 415-425 11 p.

  Research output: Contribution to journal › Article › peer-review

  • 14-O-phosphonooxymethyltriptolide
  • Pancreatic Neoplasms
  • Blood Vessels
  • Survival
  • Pharmaceutical Preparations
  37 Scopus citations
• 2020

  An Immunocompetent Model of Pancreatic Cancer Resection and Recurrence

  Giri, B., Ferrantella, A., Sharma, P., Jain, T., Jacob, H. K. C., Modi, S., Kurtom, S., Roy, P., Sethi, V., Banerjee, S., Merchant, N., Ramakrishnan, S., Saluja, A. & Dudeja, V., 2020, (Accepted/In press) In: Journal of Gastrointestinal Surgery.

  Research output: Contribution to journal › Article › peer-review

  • Pancreatic Neoplasms
  • Recurrence
  • Adenocarcinoma
  • Neoplasms
  • Circulating Neoplastic Cells
  1 Scopus citations
• 2016

  Is age just a number: pancreaticoduodenectomy in elderly patients?

  Dudeja, V. & Livingstone, A., Aug 15 2016, In: Hepatobiliary and Pancreatic Diseases International. 15, 4, p. 346-347 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  1 Scopus citations
• 2018

  Pancreatitis: A Tale of Two Proteases

  Nikam, A., Dawra, R., Saluja, A. & Dudeja, V., Feb 2018, In: Gastroenterology. 154, 3, p. 482-484 3 p.

  Research output: Contribution to journal › Editorial › peer-review
• 2020

  Symphony in chaos: Immune orchestra during pancreatic cancer progression

  Sharma, P., Jain, T., Sethi, V. & Dudeja, V., Jun 2020, In: EBioMedicine. 56, 102787.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access
• 2013

  Disparities in pancreas cancer care

  Abraham, A., Al-Refaie, W. B., Parsons, H. M., Dudeja, V., Vickers, S. M. & Habermann, E. B., Jun 1 2013, In: Annals of Surgical Oncology. 20, 6, p. 2078-2087 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreatic Neoplasms
  • Odds Ratio
  • Confidence Intervals
  • Insurance Coverage
  • Medicaid
  54 Scopus citations
• 2017

  Insights into the Pathogenesis of Pancreatic Cystic Neoplasms

  Sethi, V., Giri, B., Saluja, A. & Dudeja, V., Jul 1 2017, In: Digestive Diseases and Sciences. 62, 7, p. 1778-1786 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Pancreatic Neoplasms
  • Cysts
  • Pancreatic Intraductal Neoplasms
  • Clinical Decision-Making
  • Epidemics
  8 Scopus citations
• 2013

  Neoadjuvant chemoradiotherapy for locally advanced pancreas cancer rarely leads to radiological evidence of tumour regression

  Dudeja, V., Greeno, E. W., Walker, S. P. & Jensen, E. H., Sep 2013, In: HPB. 15, 9, p. 661-667 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Chemoradiotherapy
  • Pancreatic Neoplasms
  • Neoplasms
  • Blood Vessels
  • Mesenteric Veins
  25 Scopus citations
• 2015

  CD133 initiates tumors, induces epithelial-mesenchymal transition and increases metastasis in pancreatic cancer

  Nomura, A., Banerjee, S., Chugh, R., Dudeja, V., Yamamoto, M., Vickers, S. M. & Saluja, A. K., 2015, In: Oncotarget. 6, 10, p. 8313-8322 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Epithelial-Mesenchymal Transition
  • Pancreatic Neoplasms
  • Neoplastic Stem Cells
  • Neoplasm Metastasis
  • Membrane Glycoproteins
  63 Scopus citations
• 2017

  Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of Gastric cancer

  Arora, N., Alsaied, O., Dauer, P., Majumder, K., Modi, S., Giri, B., Dudeja, V., Banerjee, S., Von Hoff, D. & Saluja, A., Feb 2017, In: PloS one. 12, 2, e0171827.

  Research output: Contribution to journal › Article › peer-review

  • 14-O-phosphonooxymethyltriptolide
  • stomach neoplasms
  • Tumors
  • triptolide
  • Cells
  12 Scopus citations

• Inhibition of Sp1 prevents ER homeostasis and causes cell death by lysosomal membrane permeabilization in pancreatic cancer

  Dauer, P., Gupta, V. K., McGinn, O., Nomura, A., Sharma, N. S., Arora, N., Giri, B., Dudeja, V., Saluja, A. K. & Banerjee, S., Dec 1 2017, In: Scientific reports. 7, 1, 1564.

  Research output: Contribution to journal › Article › peer-review

  • Endoplasmic Reticulum Stress
  • Endoplasmic Reticulum
  • Pancreatic Neoplasms
  • Cause of Death
  • Cell Death
  8 Scopus citations
• 2016

  Inhibition of NF-kappa B pathway leads to deregulation of epithelial-mesenchymal transition and neural invasion in pancreatic cancer

  Nomura, A., Majumder, K., Giri, B., Dauer, P., Dudeja, V., Roy, S., Banerjee, S. & Saluja, A. K., Dec 1 2016, In: Laboratory Investigation. 96, 12, p. 1268-1278 11 p.

  Research output: Contribution to journal › Article › peer-review

  • 14-O-phosphonooxymethyltriptolide
  • BAY 11-7085
  • NF-kappa B
  • Epithelial-Mesenchymal Transition
  • triptolide
  34 Scopus citations
• 2017

  Inhibition of hypoxic response decreases stemness and reduces tumorigenic signaling due to impaired assembly of HIF1 transcription complex in pancreatic cancer

  McGinn, O., Gupta, V. K., Dauer, P., Arora, N., Sharma, N., Nomura, A., Dudeja, V., Saluja, A. & Banerjee, S., Dec 1 2017, In: Scientific reports. 7, 1, 7872.

  Research output: Contribution to journal › Article › peer-review

  • 14-O-phosphonooxymethyltriptolide
  • triptolide
  • Pancreatic Neoplasms
  • Hypoxia
  • Neoplasms
  16 Scopus citations
• 2016

  Release of Cathepsin B in Cytosol Causes Cell Death in Acute Pancreatitis

  Talukdar, R., Sareen, A., Zhu, H., Yuan, Z., Dixit, A., Cheema, H., George, J., Barlass, U., Sah, R., Garg, S. K., Banerjee, S., Garg, P., Dudeja, V., Dawra, R. & Saluja, A. K., Oct 1 2016, In: Gastroenterology. 151, 4, p. 747-758.e5

  Research output: Contribution to journal › Article › peer-review

  • Cathepsin B
  • Trypsin
  • Pancreatitis
  • Cytosol
  • Cause of Death
  35 Scopus citations
• 2017

  Why Do Long-Distance Travelers Have Improved Pancreatectomy Outcomes?

  Jindal, M., Zheng, C., Quadri, H. S., Ihemelandu, C. U., Hong, Y. K., Smith, A. K., Dudeja, V., Shara, N. M., Johnson, L. B. & Al-Refaie, W. B., Aug 2017, In: Journal of the American College of Surgeons. 225, 2, p. 216-225 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreatectomy
  • Mortality
  • High-Volume Hospitals
  • Rural Population
  • Neoplasms
  26 Scopus citations
• 2019

  Long non-coding RNA GAS5 acts as proliferation “brakes” in CD133+ cells responsible for tumor recurrence

  Sharma, N. S., Gnamlin, P., Durden, B., Gupta, V. K., Kesh, K., Garrido, V. T., Dudeja, V., Saluja, A. & Banerjee, S., Dec 1 2019, In: Oncogenesis. 8, 12, 68.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Long Noncoding RNA
  • Recurrence
  • Neoplastic Stem Cells
  • Growth
  • Population
  2 Scopus citations

• Tumor-targeted silencing of the peptide transporter TAP induces potent antitumor immunity

  Garrido, G., Schrand, B., Rabasa, A., Levay, A., D’Eramo, F., Berezhnoy, A., Modi, S., Gefen, T., Marijt, K., Doorduijn, E., Dudeja, V., van Hall, T. & Gilboa, E., Dec 1 2019, In: Nature communications. 10, 1, 3773.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • peptide permease
  • transporter
  • immunity
  • peptides
  • Tumors
  8 Scopus citations
• 2018

  NFκB in Pancreatic Stellate Cells Reduces Infiltration of Tumors by Cytotoxic T Cells and Killing of Cancer Cells, via Up-regulation of CXCL12

  Garg, B., Giri, B., Modi, S., Sethi, V., Castro, I., Umland, O., Ban, Y., Lavania, S., Dawra, R., Banerjee, S., Vickers, S., Merchant, N. B., Chen, S. X., Gilboa, E., Ramakrishnan, S., Saluja, A. & Dudeja, V., Sep 2018, In: Gastroenterology. 155, 3, p. 880-891.e8

  Research output: Contribution to journal › Article › peer-review

  • Pancreatic Stellate Cells
  • Up-Regulation
  • T-Lymphocytes
  • Neoplasms
  • Inbred C57BL Mouse
  33 Scopus citations
• 2016

  Diagnostic strategy and timing of intervention in infected necrotizing pancreatitis: an international expert survey and case vignette study

  Dutch Pancreatitis Study Group & Dutch Pancreatitis Study Group, 2016, In: HPB. 18, 1, p. 49-56 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreatitis
  • Necrosis
  • Fine Needle Biopsy
  • Drainage
  • Catheters
  31 Scopus citations
• 2020

  Vaccination against Nonmutated Neoantigens Induced in Recurrent and Future Tumors

  Garrido, G., Schrand, B., Levay, A., Rabasa, A., Ferrantella, A., Da Silva, D. M., D'Eramo, F., Marijt, K. A., Zhang, Z., Kwon, D., Kortylewski, M., Kast, W. M., Dudeja, V., van Hall, T. & Gilboa, E., Jul 1 2020, In: Cancer Immunology Research. 8, 7, p. 856-868 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Vaccination
  • Neoplasms
  • Antigens
  • Down-Regulation
  • transporter associated with antigen processing (TAP)

• The role of total pancreatectomy with islet autotransplantation in the treatment of chronic pancreatitis: A report from the International Consensus Guidelines in chronic pancreatitis

  Abu-El-Haija, M., Anazawa, T., Beilman, G. J., Besselink, M. G., Del Chiaro, M., Demir, I. E., Dennison, A. R., Dudeja, V., Freeman, M. L., Friess, H., Hackert, T., Kleeff, J., Laukkarinen, J., Levy, M. F., Nathan, J. D., Werner, J., Windsor, J. A., Neoptolemos, J. P., Sheel, A. R. G., Shimosegawa, T. & 2 others, Whitcomb, D. C. & Bellin, M. D., Jun 2020, In: Pancreatology. 20, 4, p. 762-771 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreatectomy
  • Chronic Pancreatitis
  • Autologous Transplantation
  • Consensus
  • Guidelines
  3 Scopus citations
• 2017

  Genetics of pancreatic cyst-cancer progression: Standing on the shoulders of giants

  Giri, B., Sethi, V., Dudeja, V., Banerjee, S., Livingstone, A. & Saluja, A., Sep 1 2017, In: Current Opinion in Gastroenterology. 33, 5, p. 404-410 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Pancreatic Cyst
  • Pancreatic Neoplasms
  • Shoulder
  • Genetic Code
  • Adenocarcinoma
  2 Scopus citations
• 2019

  Does Neoadjuvant Chemotherapy Change the Role of Regional Lymphadenectomy in Pancreatic Cancer Survival?

  Macedo, F. I., Picado, O., Hosein, P., Dudeja, V., Franceschi, D., Mesquita-Neto, J. W., Yakoub, D. & Merchant, N., Jul 1 2019, In: Pancreas. 48, 6, p. 823-831 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Lymph Node Excision
  • Pancreatic Neoplasms
  • Drug Therapy
  • Survival
  • Lymph Nodes
  1 Scopus citations
• 2014

  Triptolide activates unfolded protein response leading to chronic ER stress in pancreatic cancer cells

  Mujumdar, N., Banerjee, S., Chen, Z., Sangwan, V., Chugh, R., Dudeja, V., Yamamoto, M., Vickers, S. M. & Saluja, A. K., Jun 1 2014, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 306, 11, p. G1011-G1020

  Research output: Contribution to journal › Article › peer-review

  • triptolide
  • Unfolded Protein Response
  • Endoplasmic Reticulum Stress
  • Pancreatic Neoplasms
  • Endoplasmic Reticulum
  33 Scopus citations
• 2018

  Inactivation of cancer-associated-fibroblasts disrupts oncogenic signaling in pancreatic cancer cells and promotes its regression

  Dauer, P., Zhao, X., Gupta, V. K., Sharma, N., Kesh, K., Gnamlin, P., Dudeja, V., Vickers, S. M., Banerjee, S. & Saluja, A., Mar 1 2018, In: Cancer Research. 78, 5, p. 1321-1333 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Cancer-Associated Fibroblasts
  • Pancreatic Neoplasms
  • 14-O-phosphonooxymethyltriptolide
  • Epithelial Cells
  • Neoplasms
  34 Scopus citations
• 2019

  Extracellular release of ATP promotes systemic inflammation during acute pancreatitis

  Dixit, A., Cheema, H., George, J., Iyer, S., Dudeja, V., Dawra, R. & Saluja, A. K., Oct 1 2019, In: American journal of physiology. Gastrointestinal and liver physiology. 317, 4, p. G463-G475

  Research output: Contribution to journal › Article › peer-review

  • Pancreatitis
  • Adenosine Triphosphate
  • Inflammation
  • Apyrase
  • Ceruletide
  3 Scopus citations