Selective inhibition of Herpes simplex virus replication has been demonstrated in studies with cell culture. In the present study a significant fraction of mice survived intracranial infection of HSV, with bromodeoxycytidine and tetrahydrouridine therapy. Together, these studies suggest that the 5 halogenated analogs of deoxycytidine in combination with tethydrouridine have potential as effective agents in the therapy of herpes encephalitis as well as other herpes simplex virus infections.
|Original language||English (US)|
|Number of pages||7|
|Journal||Annals of the New York Academy of Sciences|
|State||Published - Aug 1975|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- History and Philosophy of Science