3D phase encoding 1H spectroscopic imaging of human brain

Jeff H. Duijn, Gerald B. Matson, Andrew A Maudsley, Michael W. Weiner

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

A three-dimensional (3D) phase-encoding proton spectroscopic imaging method is presented for a whole body MRI MRS system. Metabolite images at 2 T of choline, creatine, and N-acetyl aspartate (NAA) of normal brain were obtained with a spatial resolution of 1.5 cc. With PRESS volume preselection and outer volume suppression pulses, brain regions close to the skull could be studied without significant contamination by lipid and water signals.

Original languageEnglish
Pages (from-to)315-319
Number of pages5
JournalMagnetic Resonance Imaging
Volume10
Issue number2
DOIs
StatePublished - Jan 1 1992
Externally publishedYes

Fingerprint

Neuroimaging
brain
Brain
coding
creatine
aspartates
Imaging techniques
choline
skull
Creatine
metabolites
Metabolites
Choline
Skull
Magnetic resonance imaging
Lipids
lipids
Protons
contamination
Contamination

Keywords

  • Magnetic resonance
  • Proton spectroscopy
  • Spectroscopic imaging

ASJC Scopus subject areas

  • Biophysics
  • Clinical Biochemistry
  • Structural Biology
  • Radiology Nuclear Medicine and imaging
  • Condensed Matter Physics

Cite this

3D phase encoding 1H spectroscopic imaging of human brain. / Duijn, Jeff H.; Matson, Gerald B.; Maudsley, Andrew A; Weiner, Michael W.

In: Magnetic Resonance Imaging, Vol. 10, No. 2, 01.01.1992, p. 315-319.

Research output: Contribution to journalArticle

Duijn, Jeff H. ; Matson, Gerald B. ; Maudsley, Andrew A ; Weiner, Michael W. / 3D phase encoding 1H spectroscopic imaging of human brain. In: Magnetic Resonance Imaging. 1992 ; Vol. 10, No. 2. pp. 315-319.
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