3D phase encoding 1H spectroscopic imaging of human brain

Jeff H. Duijn, Gerald B. Matson, Andrew A. Maudsley, Michael W. Weiner

Research output: Contribution to journalArticlepeer-review

80 Scopus citations


A three-dimensional (3D) phase-encoding proton spectroscopic imaging method is presented for a whole body MRI MRS system. Metabolite images at 2 T of choline, creatine, and N-acetyl aspartate (NAA) of normal brain were obtained with a spatial resolution of 1.5 cc. With PRESS volume preselection and outer volume suppression pulses, brain regions close to the skull could be studied without significant contamination by lipid and water signals.

Original languageEnglish (US)
Pages (from-to)315-319
Number of pages5
JournalMagnetic Resonance Imaging
Issue number2
StatePublished - 1992
Externally publishedYes


  • Magnetic resonance
  • Proton spectroscopy
  • Spectroscopic imaging

ASJC Scopus subject areas

  • Biophysics
  • Clinical Biochemistry
  • Structural Biology
  • Radiology Nuclear Medicine and imaging
  • Condensed Matter Physics


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