Abstract
α-Synuclein, a natively unstructured protein important in the neuropathology of Parkinson's disease, was found to form a Langmuir monolayer in an α-helical conformation with its helical axis parallel to the air-water interface. This study sheds light on the role of vesicles in neuronal cells in the accumulation/aggregation of α-synuclein.
Original language | English (US) |
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Pages (from-to) | 6702-6704 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 46 |
Issue number | 36 |
DOIs | |
State | Published - Sep 28 2010 |
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- Chemistry(all)
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry