ŒSTROGEN RECEPTORS IN HUMAN MALIGNANT MELANOMA

RichardI Fisher, JamesP Neifeld, Marc E Lippman

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202 Scopus citations

Abstract

16 of 35 patients (46%) with malignant melanoma were found to have cytoplasmic œstrogen-receptor activity in biopsy specimens. Œtrogen-receptor activity was detected in primary lesions, lymph-node metastases, skin metastases, and visceral metastases. Equal percentages of males and females had positive assays. Scatchard analysis of binding in one case was consistent with a single class of high-affinity receptor sites.

Original languageEnglish
Pages (from-to)337-339
Number of pages3
JournalThe Lancet
Volume308
Issue number7981
DOIs
StatePublished - Aug 14 1976
Externally publishedYes

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Fisher, R., Neifeld, J., & Lippman, M. E. (1976). ŒSTROGEN RECEPTORS IN HUMAN MALIGNANT MELANOMA. The Lancet, 308(7981), 337-339. https://doi.org/10.1016/S0140-6736(76)92592-7