• O'Sullivan, Mary J. (PI)

Project: Research project

Project Details


The purpose of this grant is to study Human Immunodeficiency
Virus (HIV) infection in pregnancy. The prevalence of
seropositivity to the virus will be determined in all pregnant and
high risk non-pregnant women at Jackson Memorial Hospital. The
impact of pregnancy with its physiologic altered immune status on
the natural history of superimposed HIV infection will be
prospectively compared with non-pregnant infected women to
determine whether pregnancy alters the course of infection.
Whether the altered immune status of HIV infection affects
genitourinary infections in pregnancy will be assessed by studying
both infected and non-infected pregnant and non-pregnant women.
The rate of prenatal transmission (the most common cause of
AIDS in children) will be prospectively determined in the study
group. We feel strongly that the increasing incidence of
heterosexual transmission of HIV infection will have a significant
impact on women, especially in pregnancy. This study will
contribute towards determining how pregnancy affects HIV
infection, and how HIV infection impacts on other more common
infections in pregnancy.
Effective start/end date3/1/882/28/94


  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health: $495,819.00
  • National Institutes of Health
  • National Institutes of Health


  • Medicine(all)

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