SURGERY SPACE ALTERATION AND RODENT MICROISOLATION

  • Hentall, Ian, (PI)

Project: Research project

Description

The University of Illinois College of Medicine at Rockford has ten faculty
members in basic and clinical sciences conducting externally funded
research in parasitology, virology, immunology, carcinogenesis, behavioral
neuropharmacology, neurophysiology, cell biology, and experimental surgery.
Rabbits, mice, rats and hamsters are the mammals studied at present. The
animal care facility and program received its 4th consecutive 3-year full
accreditation from AAALAC in November 1991. To meet the needs of present and anticipated research projects while
remaining in full compliance with federal laws and guidelines, three
improvements in the animal care facility are required: (1) a proper
surgical suite for aseptic, survival surgery; (2) a means of preventing
microbial infection spreading between animals differing in strain, source,
or experimental treatment, which are housed in one of the nine available
holding rooms; (3) effective procedures for dealing with power outages of
up to several hours occurring several times per year. The lack of a
dedicated surgical suite, the potential for spread of infections, and the
lack of back-up power are all issues of concern in previous AAALAC
accreditation reports. It is proposed to rectify these problems in an integrated fashion. (1)
Transfer of the animal caretaker's office and the disposal freezer out of
the building zone with rapid air exchange (15 changes per hour), and
remodeling to rationalize space usage within this zone, will allow surgical
scrub and preparation/recovery rooms to be adjoined to the present surgery
room without eliminating any animal holding rooms. (2) The need for
greater isolation within individual holding rooms will be accomplished by
means of a commercial micro-isolator system with sufficient cages for small
groups of animals, (3) The micro-isolation cages also will provide an
inexpensive means of protecting critical animals (by allowing their removal
to unaffected rooms) during HVAC failures.
StatusFinished
Effective start/end date9/30/929/29/94

Funding

  • National Institutes of Health: $26,065.00

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rodents
surgery
animals
cages
virology
animal care
parasitology
neurophysiology
freezers
research projects
immunology
hamsters
infection
cell biology
compliance
carcinogenesis
medicine
rabbits
mammals
air