PROSPECTIVE EVALUATION OF RADIAL KERATOTOMY (PERK)

Project: Research project

Description

This prospective, randomized, monitored study evaluates the operation radial
keratomy for myopia, in which 16 partial thickness peripheral, radial, corneal
incisions flatten the central cornea and reduce myopia. The goal of the
operation is to give the patient 20/40 or better uncorrected visual acuity,
20/20 corrected visual acuity without fluctuation or uncomfortable glare. We
will recruit 40 myopic patients who meet the selection criteria detailed in the
manual of operations, and assign approximately 5 patients to each of 9 groups
based on their keratometry readings and refractive myopia. We will randomize
the right and left eyes. Preoperative examinations will be performed in
accordance with the manual of operations. A standardized radial keratomy
operation will then be performed. Postoperatively, the patients will be
examined at regular intervals by a physician other than the surgeon to measure
alterations in visual acuity, corneal shape, refraction and glare, endothelial
cell counts, patient satisfaction, and other variables as described in the
manual of operations. At the end of approximately 1 year, we will examine the
data to estimate the safety and efficacy of this operation in correcting myopia. These results will lead to recommendations concerning surgery on the second eye
and recommendations to the ophthalmic community. Since there are approximately
11 million myopic Americans whose nearsightedness could be corrected by this
surgery and since the surgery has been widely publicized, the social and
economic implications of this study are substantial. This carefully designed
study, which is independently monitored, should give the scientific results
necessary to make rational judgments about the role of this surgery in the
management of myopia.
StatusFinished
Effective start/end date2/1/8112/31/89

Funding

  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health

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Radial Keratotomy
Myopia
Glare
Visual Acuity
Patient Satisfaction
Cornea
Patient Selection
Reading
Physicians
Safety

ASJC

  • Medicine(all)