PREVENTING DEPRESSION IN INFANTS OF DEPRESSED MOTHERS

Project: Research project

Description

Infants of mothers who remain depressed beyond their infants' first few
months develop depressed behavior during early interactions and experience
later developmental delays. The purposes of this research are: 1) to find
predictors of the mother's continuing depression during the first few
months; 2) based on those predictors identify those mothers and infants
that will need early intervention for those dyads. For the study on
identifying risk factors for continuing depression (first 2 years) a number
of infant measures (sleep/wake and face-to-face interaction behavior,
temperament, heart rate and catecholamines/cortisol) and maternal measures
(self-reported depression, anxiety, stress and social support, interaction
behavior, EEG, EMG and catecholamines/cortisol) will be monitored at birth,
3 and 6 months in 200 dyads. Using a regression model a cumulative risk
index will be formed on the birth and 3 month measures that predicted to
continuing depression at 6 months. In a second sample of 200 depressed
mother-infant dyads the 80% expected to remain depressed will be identified
based on the high risk index score and randomly assigned to a
prevention/control group at 3 months in an attempt to prevent infant
depression by reducing depressed maternal behavior during the "critical" 3-
6 month social interaction period. The interventions are designed to
reduce those maternal behaviors that are likely to contribute to infant
depression. They include reducing depressed mood in the mothers (by music
mood induction/relaxation therapy), enhancing sensitivity to infant cues
(by infant massage and imitation/interaction coaching) and reducing
attributions of infant behavior (by video and auditory feedback). The
effects of this prevention on infant mood, behavior and development will be
assessed across the first two years.
StatusFinished
Effective start/end date2/1/911/31/03

Funding

  • National Institutes of Health: $104,777.00
  • National Institutes of Health
  • National Institutes of Health: $360,870.00
  • National Institutes of Health
  • National Institutes of Health: $388,137.00
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health: $284,909.00
  • National Institutes of Health: $334,630.00
  • National Institutes of Health
  • National Institutes of Health: $413,210.00

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Mothers
Depression
Infant Behavior
Maternal Behavior
Catecholamines
Hydrocortisone
Interpersonal Relations
Parturition
Relaxation Therapy
Temperament
Massage
Child Development
Social Support
Cues
Electroencephalography
Sleep
Anxiety
Heart Rate
Control Groups
Research

ASJC

  • Medicine(all)