Project Details
Description
DESCRIPTION (provided by applicant): The objective of this program project application is to develop novel therapeutics that target CNS and peripheral reservoirs of HIV-1 replication. Under the auspices of a U19, we have identified novel small molecules that target the vif-apobec axis and that specifically inhibit vif-dependent viral replication. Structure Activity Relationship (SAR studies have identified potent analogs (IC50
| Status | Active |
|---|---|
| Effective start/end date | 8/19/13 → 7/31/20 |
Funding
- National Institutes of Health: $1,168,508.00
- National Institutes of Health
- National Institutes of Health
- National Institutes of Health
- National Institutes of Health
- National Institutes of Health
- National Institutes of Health
- National Institutes of Health: $1,181,526.00
- National Institutes of Health
- National Institutes of Health: $1,237,491.00
- National Institutes of Health
- National Institutes of Health: $1,194,404.00
- National Institutes of Health
- National Institutes of Health
- National Institutes of Health: $1,262,306.00