Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age

Project Narrative Survival of infants born extremely prematurely has improved, but these babies go on to experience high rates of childhood health problems including asthma, breathing abnormalities during sleep, and poor developmental outcomes. Currently, the mechanisms causing such outcomes remain unclear, impairing the ability of the clinician to identify both at-risk infants and targets for intervention. This study will utilize advanced analytics platforms paired with detailed health outcomes through pre-school age in a cohort of prematurely born children to further our understanding of the pathways leading to abnormal outcomes in these children, empowering early identification and targeted treatment to improve health outcomes.