Project: Research project

Project Details


This application details a proposed drug abuse treatment development study,
submitted under the NIDA RFA #DA-94-02. Behavioral Therapies Development
Program. The primary aim of this study is to articulate, standardize, and
pilot test a comprehensive, intensive outpatient treatment for adolescent
drug abusers -Multicomponent intervention for Adolescent Drug Abuse
(CRADA). The proposed project will revise our empirically-established
family-based treatment. Multidimensional Family Therapy (MDFT). And this
reformulated MDFT intervention will be the core part of the new approach we
will develop and pilot. This study has six objectives. First, we will
identify individual and family processes that are related to success and
non-success in the treatment of adolescent drug abuse. To accomplish this,
we propose intensive analyses of archival videotape data from past and
current adolescent drug abuse treatment research in the PI's lab and the
Center's other sites. Three areas are investigated: (a) therapeutic
alliance of the therapist and adolescent, (b) in-treatment changes in
parenting practices that are related to adolescent development generally,
and adolescent drug use, in particular, and (c) culturally-related
responses to treatment for adolescent drug abuse. Our new knowledge in
these areas will be used to reformulate and enhance our current version of
MDFT. The second objective aims to specify the content and methods of two
new treatment components-modules. The new modules were chosen from the
basis of research about risk and protective factors for adolescent drug
abuse, as well as our knowledge of particular domains of functioning not
adequately addressed in the current version of MDFT. The first module aims
to alter the ecology of the treatment delivery system by having the
intervention be primarily a home-based treatment and offering case
management services. The second module adds a skills training component
(parent and adolescent skills training in groups) to the intervention. The
parent groups focus on parent management techniques and social support.
The adolescent groups focus on interpersonal and social situation appraisal
and alternative generation. The groups, along with the other modules are
offered concurrently. We will conduct a trial implementation of these
modules. The project's third objective, emanating from the first two, is
to create an enhanced, comprehensive, integrative, multicomponent
intervention for adolescent drug abusers. The new intervention, MIADA,
consists of the two new modules plus our reformulated MDFT model. All
components are offered concurrently. Fourth, we will test the preliminary
efficacy and feasibility of MIADA by comparing it to the MDFT approach in
a small scale pilot study. Subjects will be randomly assigned and an
abbreviated battery of measures will be given. Fifth, we will create a
state of the science treatment manual and corresponding videotape training
aids. And, sixth, we will develop therapist adherence and competence
measures. These are central to this study's scientific integrity as well
as to our long term aim: to crete a viable, community-based treatment with
sufficient feasibility and efficacy data to warrant the conduct of a
randomized clinical trial.
Effective start/end date9/30/948/31/98


  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health: $169,270.00


  • Medicine(all)


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