MHC OF THE RHESUS MONKEY

Project: Research project

Description

DESCRIPTION: Simian immunodeficiency
virus (SIV) infection of macaque monkeys is an important model for the
study of AIDS. The nucleotide sequence similarities to HIV and ability to
induce AIDS in macaques make SIVs and their infection of these monkeys
particularly important models for the development of AIDS vaccine
strategies. In investigating the immune response to SIV in macaques, it
will be important therefore to define the genes and gene products of the
macaque's MHC. The investigator will therefore first characterize the MHC
genes and gene products of the rhesus monkey and, and second explore the
possible relationships between certain MHC haplotypes and length of
survival after SIV infection in this species.
StatusFinished
Effective start/end date3/1/928/31/97

Funding

  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health

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Macaca
Macaca mulatta
Acquired Immunodeficiency Syndrome
Major Histocompatibility Complex
Genes
Infection
Haplorhini
Haplotypes
Research Personnel
HIV
Simian Immunodeficiency Virus
Virus Diseases

ASJC

  • Medicine(all)
  • Immunology and Microbiology(all)