MARROW TRANSP./SCID &OTHER LETHAL CONGENITAL IMMUNODEF.

  • Pahwa, Rajendra, (PI)

Project: Research project

Description

To develop improved therapeutic approaches whereby T-cell
depleted, HLA haplotype disparate marrow transplants can be
used to consistently achieve engraftment and full recovery of
immune function with graft vs. host disease in patients with: a) variants of SCID exhibiting graft resistance;
b) Other diseases associated with a lethal combined
immunodeficiency, and
c) Wiskott-Aldrich syndrome, who lack an HLA-identical donor
StatusFinished
Effective start/end date7/1/826/30/91

Funding

  • National Institutes of Health

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Severe Combined Immunodeficiency
T-Lymphocytes
Transplants
Wiskott-Aldrich Syndrome
Recovery of Function
Haplotypes
Bone Marrow
Tissue Donors
Therapeutics