MARINE/FRESHWATER BIOMEDICAL SCIENCES CENTER

  • Schmale, Michael C (PI)
  • Fieber, Lynne A (PI)
  • Fleming, Lora E, (PI)
  • Baden, Daniel (PI)
  • Gawley, Robert E. (PI)
  • Rein, Kathleen (PI)
  • Patrone, Laura (PI)
  • Nolen, Thomas (PI)
  • Flajnik, Martin F. (PI)
  • Bossart, Gregory (PI)
  • Evanseck, Jeffrey (PI)
  • Walsh, Patrick Joseph (PI)

Project: Research project

Description

This proposal is to establish a National Institute of Environmental Health
Sciences Marine and Freshwater Biomedical Science Center at the Rosenstiel
School of Marine and Atmospheric Science campus of the University of Miami.
The Center application is the collaborative effort of 4 faculty from the
marine campus, and 5 faculty from the medical campus of the University. The primary theme of the proposed Marine and Freshwater Biomedical Sciences
Center will be development and use of several marine organisms as model
systems for the investigations of how selected bioactive compounds in the
marine environment might affect the health of humans. This theme will have
several principal components: mechanisms of action of marine toxins of
significance as human disease agents, mechanisms of chemical and biological
carcinogenesis, neurophysiological responses to ischemia and marine toxins,
and alterations in immune system function produced by agents in the marine
environment. Marine animal model systems have already been identified and
characterized in the laboratories for use in each of these components.
there is extensive overlap in the research objectives involved in the
programs already underway and those planned to be integral parts of the
Center. The links between these components originate from the use of
common tools, such as marine toxins, to dissect these systems at the
functional and molecular levels. As Core support, the following are proposed as Center Units: (1)
Administration, (2) Toxin Supply, (3) Fish Tissue Culture, (4) Fish Cancer
and Immunology, (5) Electrophysiology, (6) Metabolic Neurophysiology, (7)
Metabolism and Analytical Biochemistry, (8) Electron Microscopy, (9)
Biostatistics, (10) Fish and Shellfish Hatchery, and (11) Pilot Studies.
Each component will improve collaboration between the nine Center Principal
Investigators. The University of Miami has provided a strong cost-share component
essential to achieving Center goals, and includes post-doctoral support,
cost-sharing in equipment and supplies, and travel funds for External
Advisory Committee members.
StatusFinished
Effective start/end date8/1/913/31/07

Funding

  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health: $385,389.00
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health

Fingerprint

toxin
fish
tool use
biochemistry
shellfish
immune system
electron microscopy
cost
hatchery
education
epidemiology
metabolism
animal
laboratory
algal bloom

ASJC

  • Environmental Science(all)
  • Medicine(all)