INFRASTRUCTURE SUPPORT PROGRAM

  • Nemeroff, Charles (PI)
  • Goodman, Sherryl (PI)
  • Marsteller, Frederick (PI)
  • Bonsall, Robert W. (PI)

Project: Research project

Description

The Department of Psychiatry and Behavioral Sciences of the Emory
University School of Medicine is applying for a Research Infrastructure
Program (RISP) Grant. Funds are requested for partial salary support for
junior faculty, especially women and minorities, and training expenses for
junior faculty which take the form of support of the following modules:
(l) A Patient Recruitment and Assessment Module, which will provide
standardized psychiatric diagnostic and dimensional rating scales, as well
as recruitment of patients with different psychiatric diagnoses and age-
and sex-matched normal controls; (2) A
Neuroendocrinology/Neurochemistry/Brain Imaging Module, which will provide
consultation for measurement of routine hormones and neurotransmitters
(and metabolites), as well as measurements of transporters and receptors.
In addition, measurement of the concentrations of centrally acting drugs,
including antidepressants, anxiolytics and antipsychotics in plasma and
other biological fluids is available. This module will also provide
expertise in structural (MRI) and functional (PET, SPECT, MRS) brain
imaging; (3) A Biological Tissues and Fluids Module, which will provide
for cataloging and storage of plasma, urine and cerebrospinal fluid (CSF)
samples, as well as platelets, lymphocytes and postmortem brain tissue
from well-characterized patients diagnosed in life with a major
psychiatric disorder; (4) An Experimental Design and Biostatistics Module,
which will assist junior investigators with research design, as well as
statistical analysis of the data generated. In order to maximize the
likelihood of a rapid advancement in the quality and magnitude of clinical
research in the Department, support is also requested for a modicum of
inpatient bed costs at Emory University Hospital, travel support for
junior faculty to attend national meetings, as well as for funding of an
external Scientific Advisory Board to convene at Emory once per year to
review the program. The support provided by the RISP, together with that
provided to the Department by the Emory University School of Medicine (new
laboratory and office space, seed money for new faculty, and support of
senior faculty, as well as the new positron-emission tomography (PET)
center), taken together with the more than ample patient population in the
greater Atlanta area, will result in significant and lasting improvements
in the Department's capacity to obtain extramural research funding.
StatusFinished
Effective start/end date8/1/947/31/00

Funding

  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health

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Positron-Emission Tomography
Patient Selection
Research
Research Design
Cataloging
Psychiatry
Medicine
Biostatistics
Behavioral Sciences
Neurochemistry
Neuroimaging
Salaries and Fringe Benefits
Anti-Anxiety Agents
Financial Management
Single-Photon Emission-Computed Tomography
Mental Disorders
Antidepressive Agents
Antipsychotic Agents
Neurotransmitter Agents
Cerebrospinal Fluid

ASJC

  • Medicine(all)