Human T cell Lymphotropic Virus Vaccine development

Project: Research project

Project Details

Description

PROJECT NARRATIVE: Human T cell Leukemia Virus type-1 (HTLV-1) is a human retrovirus that is the causative agent of a malignant CD4+ T cell lymphoproliferation referred to as Adult T cell leukemia/lymphoma (ATLL), as well as several inflammatory disorders with the most problematic being human myelopathy/tropical spastic paraparesis (HAM/TSP). Remarkably, while millions are affected worldwide, there are no effective vaccines to prevent associated disease or treatment options for ATLL or HAM/TSP afflicted individuals. We thus aim here, to develop a candidate vaccine to prevent and plausibly treat HTLV-1-associated disease.
StatusActive
Effective start/end date2/1/221/31/23

Funding

  • National Institute of Allergy and Infectious Diseases: $299,860.00

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