HEMATOPOIESIS IN RETROVIRUS INFECTED SIMIANS

  • Weiss, Roy E (PI)
  • Weiss, Roy E (PI)
  • Weiss, Roy E (PI)
  • Rosenberg, Irwin (PI)
  • Weiss, Ned M. (PI)
  • Goldberg, Leon (PI)
  • Schuster, Charles (PI)
  • Rabinovich, C. Egla (PI)
  • Kremser, Cynthia (PI)
  • Buse, John (PI)
  • Solway, Julian (PI)
  • Josephson, Michelle (PI)
  • Asplin, John (PI)
  • Herbst, Arthur L. (PI)
  • Lashner, Bret (PI)
  • Mazzone, Theodore (PI)
  • Kreiter, Mary (PI)
  • Dewit, Harriet (PI)
  • Brown, Frederick D. (PI)
  • Scoeller, Dale (PI)
  • Rajfer, Sol (PI)
  • Pononsky, Kenneth (PI)
  • Richman, David (PI)
  • Douglas, Frank L. (PI)
  • Baron, Joseph M. (PI)
  • Thistlethwaite, J. Richard (PI)
  • Meltzer, Herbert Yale (PI)
  • Johanson, Chris E. (PI)
  • Chelmickaschorr, E.V.A. (PI)
  • Arcilla, Rene (PI)
  • Zacny, James (PI)
  • Roos, Raymond P. (PI)
  • Polansky, Kenneth (PI)
  • Scany, Angelo M. (PI)
  • Tartof, David (PI)
  • Davidson, Nicholas (PI)
  • Lichtor, J. Lance (PI)
  • Knowles, Jarol B. (PI)
  • Jonas, Richard B. (PI)
  • January, Craig (PI)
  • Hall, Jesse (PI)
  • Roizan, Nancy (PI)
  • Voke, Tamara (PI)
  • Cara, Jose (PI)
  • Cuttler, Leona (PI)
  • Senay, Edward (PI)
  • Beebe, Christine A. (PI)
  • Loy, Gary (PI)
  • Palonsky, Kenneth S. (PI)
  • Huttenlocher, Peter (PI)
  • Barron, William M. (PI)
  • Aycinena, P. (PI)
  • Kaplan, Edward (PI)
  • Benca, Ruth (PI)
  • Antel, Jack (PI)
  • Murphy, Michael B. (PI)
  • Degroot, Leslie (PI)
  • Baker, Alfred L. (PI)
  • Schueller, Dale (PI)
  • Cohen, Louis (PI)
  • Burstein, Stephen (PI)
  • Robertson, Gary L. (PI)
  • Roizen, Nancy (PI)
  • Fellner, Susan K. (PI)
  • Samuels, Brian (PI)
  • Sommerfeld, Eberhard (PI)
  • Lau, Kai (PI)
  • Kaplan, Edwin (PI)
  • Landau, Richard (PI)
  • Kirschner, Barbara (PI)
  • Saper, Clifford (PI)
  • Hopkins, Joyce (PI)
  • Reder, Anthony T. (PI)
  • Jones, Thomas (PI)
  • Fang, Victor S. (PI)
  • Berkelhammer, Charles (PI)
  • Rose, Robert P. (PI)
  • Apfelbaum, Jeffrey (PI)
  • Jonghorbani, Morteza (PI)
  • Schuette, Sally (PI)
  • Pliskin, Neil (PI)
  • Scanu, Angelo (PI)
  • Sarne, David (PI)
  • Moll, George W. (PI)
  • Goldman, Morris (PI)
  • Crayton, John (PI)
  • Sitrin, Michael (PI)
  • Golomb, Harvey (PI)
  • Richards, Jon (PI)
  • Jaspar, Jonathan (PI)
  • Little, Alex G. (PI)
  • Jaspan, Jonathan B. (PI)
  • Bergenstal, Richard (PI)
  • Rubenstein, Arthur H. (PI)
  • Roizen, Michael (PI)
  • Lang, Roberto (PI)
  • Cura, Jose (PI)
  • Rolzen, Michael (PI)
  • Lindheimer, Marshall (PI)
  • Chait, Larry (PI)
  • Whitington, Peter (PI)
  • King, Donald (PI)
  • Yost, Michael (PI)
  • Hellman, Samuel (PI)
  • Arnason, Barry (PI)
  • Mani, Sridhar (PI)
  • Sarpong, Sampson (PI)
  • Johnson, Daniel (PI)
  • Draganich, Louis Frank (PI)
  • McClintock, Martha (PI)
  • Ndukwu, I. (PI)
  • Getz, Godfrey Shalom (PI)
  • Keenan, Kathryn Elizabeth (PI)
  • Steele, Glenn (PI)
  • Murray, Patrick (PI)
  • Kindler, Hedy (PI)
  • Conjeevaram, Hari (PI)
  • Olopade, Olufunmilayo (PI)
  • McNally, Beth (PI)
  • Ratain, Mark (PI)
  • Kyle, John (PI)
  • King, Andrea (PI)
  • Yuan, Chun- (PI)
  • Vogelzang, Nicholas (PI)
  • Ehrenpreis, Eli (PI)
  • Cook, Edwin (PI)
  • Weir, Bryce (PI)
  • [No Value], Frederick L. (PI)
  • Vokes, Tamara (PI)
  • Madara, James (PI)
  • Reimann, Keith (PI)
  • Vokes, Everett (PI)
  • Woodle, E. Steve (PI)
  • Covert, Robert (PI)
  • Ehrman, David (PI)
  • Lauderdale, Diane (PI)
  • Gajewski, Thomas (PI)
  • Ober, Carole (PI)
  • McBurnett, Keith (PI)
  • Clark, Marcus (PI)
  • Brady, Lynda (PI)
  • Rosenfield, Robert (PI)
  • Brady, Lynda (PI)
  • Ober, Carole (PI)
  • Hanauer, Stephen B. (PI)
  • McBurnett, Keith (PI)
  • Keenan, Kathryn Elizabeth (PI)
  • Murray, Patrick (PI)
  • van Cauter, E.V.E. (PI)
  • Kindler, Hedy (PI)
  • Rabinovich, Consuelo Diana (PI)
  • Conjeevaram, Hari (PI)
  • Lauderdale, Diane (PI)
  • Refetoff, Samuel (PI)
  • Schilsky, Richard (PI)
  • Olopade, Olufunmilayo (PI)
  • Bell, Graeme (PI)
  • Ehrman, David (PI)
  • Polonsky, Kenneth (PI)
  • McNally, Beth (PI)
  • De, Harriet (PI)
  • Barnes, Randall (PI)
  • Ehramann, David (PI)
  • Ratain, Mark (PI)
  • Cho, Judy (PI)
  • Clark, Marcus (PI)
  • Gajewski, Thomas (PI)
  • Kyle, John (PI)
  • King, Andrea (PI)
  • Yuan, Chun- (PI)
  • Vogelzang, Nicholas (PI)
  • Ehrenpreis, Eli (PI)
  • Cook, Edwin (PI)
  • Favus, Murray (PI)
  • Ehrmann, David (PI)
  • David, Frank (PI)
  • Refetoff, Samuel (PI)
  • Sokoloff, Mitchell (PI)
  • Phillipson, Leslie (PI)
  • Hall, Jesse B. (PI)
  • Radovick, Sally (PI)
  • Vogelzang, Nicholas (PI)
  • Kim, Karen (PI)
  • Dachman, Abraham (PI)
  • Owley, Thomas (PI)
  • Alverdy, John C. (PI)
  • Mc Closkey, Michael (PI)
  • Te, Helen (PI)
  • Rosenfield, Robert (PI)
  • Garfinkel, Marc (PI)
  • Cocca, Emil Frank (PI)
  • McConville, John (PI)
  • Ober, Carole (PI)
  • White, Steven (PI)
  • van Cauter, E.V.E. (PI)
  • McNally, Elizabeth (PI)
  • Royce, Lee (PI)
  • Lipton, Rebecca B. (PI)
  • De, Harriet (PI)
  • Cho, Judy (PI)
  • Penev, Plamen (PI)
  • King, Andrea (PI)
  • Yuan, Chun- (PI)
  • Ehrmann, David (PI)
  • Brendler, Charles (PI)
  • Philipson, Louis H. (PI)
  • Lopez, John (PI)
  • Reutrakul, Sirimon (PI)
  • Faxon, David Parker (PI)
  • Favus, Murray (PI)
  • Burnett, Deborah (PI)
  • Utset, Tammy (PI)
  • Ratain, Mark (PI)
  • Sperling, Anne I. (PI)
  • Stephenson, Mary (PI)
  • Lahn, Bruce (PI)
  • Noth, Imre (PI)
  • Phan, K. Luan (PI)
  • Refetoff, Samuel (PI)
  • Pannain, Silvana (PI)
  • Nicolae, Dan Liviu (PI)
  • Gomberg-Maitland, Mardi (PI)
  • Bell, Graeme (PI)
  • [No Value], Nancy J. (PI)
  • Burnet, Deborah (PI)
  • Tasali, Esra (PI)
  • Olopade, Funmi (PI)
  • Clark, Marcus (PI)
  • Favus, Murray (PI)
  • Maitland, Michael L. (PI)
  • Le Grange, Daniel (PI)
  • Kusher, Robert (PI)
  • Byrne, Maria (PI)
  • Clarke, Bart (PI)
  • Umans, Jason (PI)
  • Ober, Carole (PI)
  • Aikens, James (PI)
  • Herold, Kevan (PI)
  • Schoeller, Dale A. (PI)
  • Gerber, Glenn (PI)
  • Lichtor, J. (PI)
  • Wagner-Weiner, Linda (PI)
  • Yurk, Helene (PI)
  • Scholler, Dale (PI)
  • Albert, Daniel (PI)
  • Fleming, Gini (PI)
  • Bartosh, Sharon (PI)
  • Kushner, Robert F. (PI)
  • Foss, Joseph (PI)
  • Rosenfield, Robert L. (PI)
  • Hanauer, Stephen (PI)
  • Favus, Murray J. (PI)
  • van Cauter, E.V.E. (PI)
  • Rabinovich, Consuelo Diana (PI)
  • Refetoff, Samuel (PI)
  • Schilsky, Richard (PI)
  • Bell, Graeme (PI)
  • Polonsky, Kenneth (PI)
  • De, Harriet (PI)
  • Barnes, Randall B. (PI)
  • Ehramann, David (PI)
  • Cho, Judy (PI)
  • Ehrmann, David (PI)

Project: Research project

Description

This research proposal is to establish the macaque monkey as a model for
studying normal primate hematopoiesis. During years 1-3, the
distribution of lymphocyte subsets within bone marrow, lymph node,
spleen, and peripheral blood compartments will be compared and the
maturation and turnover of specific subsets of cells will be assessed
using cell cycle analysis and dual fluorescence flow cytometry. These
techniques, together with assays to assess maturation of cells of the
monocytic/granulocytic series will be employed to study the
hematopathology associated with type D retrovirus and SIV infection of
macaques. Studies during years 4 and 5 will extend the observations on
mechanisms of virus induced hematopathology and begin to explore
domestic species as models for hematopoiesis.
StatusFinished
Effective start/end date12/1/782/28/11

Funding

  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health

Fingerprint

Hematopoiesis
Adrenocorticotropic Hormone
Cushing Syndrome
Retroviridae Infections
Thyroid Hormone Resistance Syndrome
Lymphocyte Subsets
Macaca
Pituitary Neoplasms
Hydrocortisone
Primates
Pituitary ACTH Hypersecretion
Haplorhini
Cell Cycle
Flow Cytometry
Research Design
Spleen
Fluorescence
Lymph Nodes
Bone Marrow
Viruses

ASJC

  • Medicine(all)