Project: Research project

Project Details


This application proposes to conduct a Stage 1 treatment development
study targeting a subtype of drug abusing adolescent, those with
Borderline Personality Disorder (BPD), that has proved to be
particularly difficult to treat. The proposed intervention, Borderline
Adolescent Family Therapy (BAFT) integrates two successful traditions in
intervention research: Structural Family Therapy for drug abusing
adolescents with individual skills building components derived from the
work of Marsha Linehan with Borderlines. The proposed study is divided
into two phases. Phase I is the BAFT development phase including:
developing a "working" BAFT manual integrating individual and family
components based on archived videotapes, conducting BAFT with three
cases to determine ways of enhancing feasibility and acceptability of
the modality, and enhancing the focus of BAFT interventions on
mechanisms of change specific to families of BPD drug abusing
adolescents; and developing a refined BAFT manual, a manual for
therapist selection and training, and a measure of adherence. Phase II
consists of a randomized pilot study of 24 cases using a control
condition comprised of referrals to community agencies. Analyses are
intended to provide information for determining effect sizes for the
analyses that will be required in a Stage II efficacy trial, viz.,
MANOVAs on outcomes (drug abuse, borderline behaviors, conduct problems,
and markers of individuals skills development); MANOVAs on postulated
mechanisms of actions (family patterns of interactions,
negativity/positivity, and therapeutic alliances). Moreover, analyses
of clinical significance will be used to identify subgroups for whom the
intervention works best, and growth curve analyses will be used to
compare the course of change in mechanisms of action between successful
and unsuccessful cases.
Effective start/end date4/20/973/31/01


  • National Institute on Drug Abuse
  • National Institute on Drug Abuse
  • National Institute on Drug Abuse


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