• Miller, Tracie L (PI)
  • Newburg, David S. (PI)
  • Walker, W. Allan (PI)
  • Hai Ning, Shi (PI)
  • Wershil, Barry K. (PI)
  • Jaksic, T.O.M. (PI)
  • Castillo, Leticia (PI)
  • Bode, Barrie (PI)
  • Madara, James (PI)
  • Wessling-Resnick, Marianne (PI)
  • Sanderson, Ian (PI)
  • Young, Vernon (PI)
  • Ausubel, Frederick (PI)
  • Grinspoon, Steven (PI)

Project: Research project

Project Details


We propose to establish, as a new institutional resource,
a Clinical Nutrition Research Unit (CNRU) at the
Massachusetts General Hospital of Harvard Medical School
(HMS) in collaboration with the Clinical Research Center,
Massachusetts Institute of Technology (M.I.T.) and the
Department of Nutrition, Harvard School of Public Health
(HSHP). The overall goal of this CNRU is to provide high
quality research which will yield insights into the cause
and pathogenesis of nutrition-related disease and lead to
improved therapeutic approach to nutrition care. The major
specific aims are: 1) to provide research in basic areas of
biology relevant to problems in clinical nutrition; 2) to
promote the study of clinical nutrition and application of
knowledge derived there form within the HMS, M.I.T. and
HSHP community; 3) to promote interactions among scientists
and clinical investigators to show relevance to advancing
the science of clinical nutrition; and 4) to attract
"basic" investigators into the domain of clinical nutrition
to promote an environment and mechanism to develop new
investigator-initiated research. These aims will be
facilitated through the functioning of several CNRU
biomedical core resources; (a) Molecular Biology; (b)
Morphology/Tissue Culture/Flow Cytometry; and (c) Mass
Spectrometry. These cores will serve as an important way
to coordinate access of CNRU investigators in the rich and
exciting scientific expertise available in these areas
within CNRU. A pilot/feasibility program in support of the
above aims will place special emphasis on proposal to
explore the extension of work emerging from laboratories of
basic scientist in a manner relevant to the understanding
and resolution of clinical nutrition problems. Here the
research proposed extends from the level of the gene to
treat of integrated, complex patient. Additionally, an
education enrichment program is proposed including
seminars, short-courses, colloquia, tutorials and formal
didactic classroom presentations in the immediate
academic/hospital area. This revised CNRU will effectively
promote the quality and extent of nutrition research in the
HMS/MIT/HSHP area and increase the awareness of nutrition
and etiology and management of various disease states and
in the maintenance of vigorous health.
Effective start/end date9/30/947/31/22


  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health


  • Medicine(all)


Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.