BEHAVORIAL INTERVENTIONS FOR WOMEN WITH HIV/AIDS

Project: Research project

Project Details

Description

DESCRIPTION (Adapted from Applicant's Abstract): The principal objective of
this proposed multisite clinical trial is to continue efforts to develop the
most effective combination of behavioral interventions to optimize the health
status of the most neglected and understudied population affected by the AIDS
epidemic in this country: poor women of color living with HIV/AIDS. Findings
from the current study with this population affirm the utility of
cognitive-behavioral stress management training combined with
expressive-supportive therapy (CBSM+) in reducing distress (depression,
anxiety) and denial, while improving social support, self-efficacy, coping
skills and quality of life. The proposed study will extend these findings in
seeking to determine whether exposure to CBSM+ can significantly improve the
ability of the participants to take advantage of a health behavior change
program encouraging the adoption and maintenance of healthier lifestyle
behaviors (high levels of medication adherence, appropriate nutritional intake
and physical activity, safer sexual practices and reduced substance use/abuse)
essential for optimal health in the context of living with HIV/AIDS. A
corollary objective will be to determine whether the proposed intervention
program will be beneficial to less-acculturated segments of the affected
population (i.e., non-English speaking women with HIV/AIDS) by establishing
culturally- and linguistically-sensitive versions of the program in Spanish and
Creole.

To accomplish these objectives, the proposed Phase III multisite clinical trial
described in two linked interactive research project grant applications (Miami-
S. Weiss, P.I.; New York/New Jersey- J. Tobin, P.I.) will randomize 450
ethnically diverse women living with HIV/AIDS in the three major epicenters for
women (Miami: n = 180; New York: n = 180; New Jersey: n = 90) into a group
CBSM+ condition and an individual psycoeducational comparison condition (Phase
I). Following Phase I, participants will be randomized by group or cohort into
a group "Healthier Lifestyles" skills training program or an individual health
educational control condition (Phase II) devoted to improving medication
adherence, nutrition, physical activity, safer sex and substance use reduction.
Follow-up assessments will be carried out at 6, 12, and 24 months after
treatment.
StatusFinished
Effective start/end date9/30/968/31/06

Funding

  • National Institute of Mental Health: $591,977.00
  • National Institute of Mental Health: $840,934.00
  • National Institute of Mental Health: $383,931.00
  • National Institute of Mental Health: $846,133.00
  • National Institute of Mental Health
  • National Institute of Mental Health: $778,081.00
  • National Institute of Mental Health
  • National Institute of Mental Health
  • National Institute of Mental Health

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