Project: Research project

Project Details


Recent advances in pharmacotherapy that have helped contain the AIDS
virus, have dramatically increased the need for psychosocial interventions
that can concurrently facilitate drug adherence, promote harm reduction,
decrease anxiety and depressed affect, improve quality of life, and
explore possibilities for optimizing immune functioning in diverse and
often hard to reach populations. These populations include low
socioeconomic status minority and/or substance abuse individuals. This 5
year program project continuation would meet these objectives using
cognitive-behavioral stress management (CBSM) as the intervention,
primarily in Black, Hispanic and non-Hispanic White men and women.
Projects 0002 and would examine the effects of CBSM in symptomatic HIV+
gay men and in women, respectively, as a function of psychosocial,
endocrine, immune and health status variables. Because chronic
physiological arousal may adversely impact immune function and disease
progression and because we have found that HIV+ versus HIV- individuals
differ in their endocrine and immune responses to acute stressors, Project
0002 will conduct pre- versus post-CBSM psychophysiological laboratory
studies to examine the effects that the CBSM program and the
implementation of trained relaxation responses have on acute stress
responses in HIV+ individuals. The projects will each be supported by
administrative, health, psychosocial, endocrinology, immunology, and data
management and statistics core units.
Effective start/end date2/1/9312/31/04


  • National Institute of Mental Health
  • National Institute of Mental Health: $2,661,610.00
  • National Institute of Mental Health: $128,649.00
  • National Institute of Mental Health: $3,046,633.00


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