Project: Research project

Project Details


The University of Miami proposes to participate as a clinical center in
the African American Study of Kidney Disease (AASK) to compare the
efficacy of double-masked administration of randomized antihypertensive
drugs on blood pressure control and progressive renal disease. A team of physicians and paramedical personnel, most of whom were involved
in the NIH sponsored Modification of Diet in Renal Disease Study and
experienced in the longterm care of patients with hypertension and renal
disease, is committed to an effective conduct of the Study. An
administrative center within the Division of Nephrology and an outpatient
clinic center will be dedicated to the AASK Miami team. The Clinical
Research Center will be used for patients requiring hospitalization.
Laboratory, pharmacy and radiopharmacy support will be provided by the
University of Miami Hospital and Clinics. Potentially eligible African-American men and women can be identified on-
campus from the Renal and Hypertension, General Medicine, and family
Medicine Clinics at the University of Miami/Jackson Memorial Medical
Center, and the Renal and Hypertension Clinics at the Miami Veterans
Administration Medical Center, and the Clinics of UM Care and Jackson
Memorial Medical Center Health Plans. Enrollment of patients will also be
sought off-campus from nephrologists in practice, the Association of Black
Cardiologists, the Dade County Medical Association, local HMO's, family
medicine practice groups, and directly, through local advertisement within
the African-American community through newspapers, radio, television,
churches, social organizations, and the Dade County School District. The
population available and the interest in the Study by patients and
physicians alike indicate that 65 selected volunteer patients with
hypertension and chronic renal disease from arteriolar nephrosclerosis can
be entered, randomized and followed in Miami. The Miami team is committed
to accept and implement the common protocol and procedures approved by the
Steering Committee and NIDDK staff.
Effective start/end date8/15/946/30/09


  • National Institutes of Health: $293,130.00
  • National Institutes of Health: $41,412.00
  • National Institutes of Health: $167,076.00
  • National Institutes of Health: $137,932.00
  • National Institutes of Health: $164,077.00
  • National Institutes of Health: $167,076.00
  • National Institutes of Health: $167,076.00


  • Medicine(all)


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