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Zhibin Chen

Associate Professor

  • 3231 Citations
20002023
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  • 9 Similar Profiles
Autoimmunity Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Regulatory T-Lymphocytes Medicine & Life Sciences
Type 1 Diabetes Mellitus Medicine & Life Sciences
Immune Tolerance Medicine & Life Sciences
Autoimmune Diseases Medicine & Life Sciences
Genes Medicine & Life Sciences
Microbiota Medicine & Life Sciences

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Projects 2009 2023

Mucosal surface and skin protection by MHC class I-based immune regulation

Chen, Z.

National Institutes of Health

11/15/18 → 10/31/23

Project: Research project

Regulatory T-Lymphocytes
Skin
Microbiota
T-Lymphocytes
Antigens

Role of Th1/17 in gastric tumor initiation triggered by CTLA4 dysregulation

Chen, Z.

National Institutes of Health

7/1/13 → 6/30/16

Project: Research project

Stomach Neoplasms
Stomach
Neoplasms
Metaplasia
Carcinogenesis

The quantitative biology of CTLA4 splice variants in T1D

Chen, Z.

National Institutes of Health

9/20/09 → 6/30/14

Project: Research project

Type 1 Diabetes Mellitus
RNA Interference
T-Lymphocytes
Immune Tolerance
Premature Mortality

Research Output 2000 2018

  • 3231 Citations
  • 34 Article
  • 1 Review article
2 Citations (Scopus)

Identification of a gene-expression predictor for diagnosis and personalized stratification of lupus patients

Ding, Y., Li, H., He, X., Liao, W., Yi, Z., Yi, J., Chen, Z., Moore, D. J., Yi, Y. & Xiang, W., Jul 1 2018, In : PLoS One. 13, 7, e0198325.

Research output: Contribution to journal › Article

lupus erythematosus
Gene expression
Systemic Lupus Erythematosus
Gene Expression
gene expression
1 Citation (Scopus)

Identification of epigenetic modulators in human breast cancer by integrated analysis of DNA methylation and RNA-Seq data

Zhou, X., Chen, Z. & Cai, X., Jan 1 2018, (Accepted/In press) In : Epigenetics.

Research output: Contribution to journal › Article

DNA Methylation
Epigenomics
RNA
Breast Neoplasms
Methylation
2 Citations (Scopus)

Initiation of inflammatory tumorigenesis by CTLA4 insufficiency due to type 2 cytokines

Miska, J., Lui, J. B., Toomer, K. H., Devarajan, P., Cai, X., Houghton, J. M., Lopez, D. M., Abreu, M. T., Wang, G. & Chen, Z., Mar 1 2018, In : Journal of Experimental Medicine. 215, 3, p. 841-858 18 p.

Research output: Contribution to journal › Article

Carcinogenesis
Cytokines
Inflammation
Stomach Neoplasms
Immunity
6 Citations (Scopus)

Altered homeostasis and development of regulatory T cell subsets represent an IL-2R–dependent risk for diabetes in NOD mice

Dwyer, C. J., Bayer, A. L., Fotino, C., Yu, L., Cabello-Kindelan, C., Ward, N. C., Toomer, K. H., Chen, Z. & Malek, T., Dec 19 2017, In : Science Signaling. 10, 510, eaam9563.

Research output: Contribution to journal › Article

Inbred NOD Mouse
T-cells
T-Lymphocyte Subsets
Regulatory T-Lymphocytes
Medical problems
27 Citations (Scopus)

Breast cancers from black women exhibit higher numbers of immunosuppressive macrophages with proliferative activity and of crown-like structures associated with lower survival compared to non-black Latinas and Caucasians

Sengul, T., Santander, A. M., Miao, F., Sanchez, L. G., Jorda, M., Glück, S., Ince, T., Nadji, M., Chen, Z., Penichet, M. L., Cleary, M. P. & Torroella-Kouri, M., Jul 1 2016, In : Breast Cancer Research and Treatment. 158, 1, p. 113-126 14 p.

Research output: Contribution to journal › Article

Immunosuppressive Agents
Crowns
Hispanic Americans
Macrophages
Breast Neoplasms