Xue Z Liu

Professor

  • 6482 Citations
1993 …2023

Research output per year

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Research Output

2019

A novel ABHD12 nonsense variant in Usher syndrome type 3 family with genotype-phenotype spectrum review

Li, T., Feng, Y., Liu, Y., He, C., Liu, J., Chen, H., Deng, Y., Li, M., Li, W., Song, J., Niu, Z., Sang, S., Wen, J., Men, M., Chen, X., Li, J., Liu, X. Z. & Ling, J., Jul 1 2019, In : Gene. 704, p. 113-120 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

ClinGen expert clinical validity curation of 164 hearing loss gene–disease pairs

on behalf of the ClinGen Hearing Loss Clinical Domain Working Group, Jan 1 2019, In : Genetics in Medicine.

Research output: Contribution to journalArticle

6 Scopus citations

Correction: ClinGen expert clinical validity curation of 164 hearing loss gene–disease pairs (Genetics in Medicine, (2019), 10.1038/s41436-019-0487-0)

on behalf of the ClinGen Hearing Loss Clinical Domain Working Group, Jan 1 2019, (Accepted/In press) In : Genetics in Medicine.

Research output: Contribution to journalComment/debate

Open Access
Open Access
1 Scopus citations

Extrusion pump ABCC1 was first linked with nonsyndromic hearing loss in humans by stepwise genetic analysis

Li, M., Mei, L., He, C., Chen, H., Cai, X., Liu, Y., Tian, R., Tian, Q., Song, J., Jiang, L., Liu, C., Wu, H., Li, T., Liu, J., Li, X., Yi, Y., Yan, D., Blanton, S. H., Hu, Z., Liu, X. & 3 others, Li, J., Ling, J. & Feng, Y., Jan 1 2019, In : Genetics in Medicine.

Research output: Contribution to journalArticle

Genetics of Hearing Loss

Rudman, J. & Liu, X. Z., Apr 1 2019, In : Hearing Journal. 72, 4, p. 6-7 2 p.

Research output: Contribution to journalEditorial

New Genotypes and Phenotypes in Patients with 3 Subtypes of Waardenburg Syndrome Identified by Diagnostic Next-Generation Sequencing

Li, W., Mei, L., Chen, H., Cai, X., Liu, Y., Men, M., Liu, X. Z., Yan, D., Ling, J., Feng, Y. & Dorszewska, J., Jan 1 2019, In : Neural Plasticity. 2019, 7143458.

Research output: Contribution to journalArticle

Open Access

Otopathogenic Staphylococcus aureus Invades Human Middle Ear Epithelial Cells Primarily through Cholesterol Dependent Pathway

Mittal, R., Debs, L. H., Patel, A. P., Nguyen, D., Blackwelder, P., Yan, D., Weckwerth, P. H. & Liu, X. Z., Dec 1 2019, In : Scientific reports. 9, 1, 10777.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Preclinical assessment of MEK1/2 inhibitors for neurofibromatosis type 2-associated schwannomas reveals differences in efficacy and drug resistance development

Fuse, M. A., Dinh, C. T., Vitte, J., Kirkpatrick, J., Mindos, T., Plati, S. K., Young, J., Huang, J., Carlstedt, A., Franco, M. C., Brnjos, K., Nagamoto, J., Petrilli, A. M., Copik, A. J., Soulakova, J. N., Bracho, O., Yan, D., Mittal, R., Shen, R., Telischi, F. F. & 5 others, Morrison, H., Giovannini, M., Liu, X. Z., Chang, L. S. & Fernandez-Valle, C., Mar 18 2019, In : Neuro-Oncology. 21, 4, p. 486-497 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Role of microRNAs in inner ear development and hearing loss

Mittal, R., Liu, G., Polineni, S. P., Bencie, N., Yan, D. & Liu, X. Z., Feb 20 2019, In : Gene. 686, p. 49-55 7 p.

Research output: Contribution to journalReview article

The Generation of Zebrafish Mariner Model Using the CRISPR/Cas9 System

Zou, B., Desmidt, A. A., Mittal, R., Yan, D., Richmond, M., Tekin, M., Liu, X. & Lu, Z., Jan 1 2019, (Accepted/In press) In : Anatomical Record.

Research output: Contribution to journalArticle

1 Scopus citations

Zebrafish Model for Nonsyndromic X-Linked Sensorineural Deafness, DFNX1

DeSmidt, A. A., Zou, B., Grati, M., Yan, D., Mittal, R., Yao, Q., Richmond, M. T., Denyer, S., Liu, X. Z. & Lu, Z., Jan 1 2019, In : Anatomical Record.

Research output: Contribution to journalArticle

3 Scopus citations
2018

A dominant variant in the PDE1C gene is associated with nonsyndromic hearing loss

Wang, L., Feng, Y., Yan, D., Qin, L., Grati, M., Mittal, R., Li, T., Sundhari, A. K., Liu, Y., Chapagain, P., Blanton, S. H., Liao, S. & Liu, X. Z., Jun 2 2018, (Accepted/In press) In : Human Genetics. p. 1-10 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Amino acid 118 in the deafness causing (DFNA20/26) ACTG1 gene is a mutational hot spot

Wang, L., Yan, D., Qin, L., Li, T., Liu, H., Li, W., Mittal, R., Yong, F., Chapagain, P., Liao, S. & Liu, X. Z., Jun 1 2018, In : Gene Reports. 11, p. 264-269 6 p.

Research output: Contribution to journalArticle

A novel splicing mutation in SMPX is linked to nonsyndromic progressive hearing loss

Niu, Z., Yan, D., Bressler, S., Mei, L., Feng, Y. & Liu, X. Z., Jan 1 2018, In : International Journal of Pediatric Otorhinolaryngology. 104, p. 47-50 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

An update on phosphodiesterase mutations underlying genetic etiology of hearing loss and retinitis pigmentosa

Mittal, R., Bencie, N., Parrish, J. M., Liu, G., Mittal, J., Yan, D. & Liu, X. Z., Feb 8 2018, In : Frontiers in Genetics. 9, FEB, 9.

Research output: Contribution to journalComment/debate

1 Scopus citations

A possible association between hearing loss and Zika virus infections

Mittal, R., Fifer, R. & Liu, X. Z., Jan 1 2018, In : JAMA Otolaryngology - Head and Neck Surgery. 144, 1, p. 3-4 2 p.

Research output: Contribution to journalComment/debate

6 Scopus citations

A xenograft model of vestibular schwannoma and hearing loss

Dinh, C. T., Bracho, O., Mei, C., Bas Infante, E., Fernandez-Valle, C., Telischi, F. F. & Liu, X. Z., Jun 1 2018, In : Otology and Neurotology. 39, 5, p. e362-e369

Research output: Contribution to journalArticle

2 Scopus citations

ELMOD3, a novel causative gene, associated with human autosomal dominant nonsyndromic and progressive hearing loss

Li, W., Sun, J., Ling, J., Li, J., He, C., Liu, Y., Chen, H., Men, M., Niu, Z., Deng, Y., Li, M., Li, T., Wen, J., Sang, S., Li, H., Wan, Z., Richard, E. M., Chapagain, P., Yan, D., Liu, X. Z. & 2 others, Mei, L. & Feng, Y., Apr 1 2018, In : Human Genetics. 137, 4, p. 329-342 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

First locally acquired congenital zika syndrome case in the United States: Neonatal clinical manifestations

Ventura, C. V., Bandstra, E. S., Fernandez, M. P., Cooper, J. M., Saigal, G., Bauer, C. R., Hofheimer, J. A., Berkovits, M., Fifer, R., Pensirikul, A., Gonzalez, I., Curry, C., Andreansky, S., Younis, R. T., Liu, X. Z., Banker, T., Dubovy, S., Langer, S. M. & Berrocal, A., Sep 1 2018, In : Ophthalmic Surgery Lasers and Imaging Retina. 49, 9, p. e93-e98

Research output: Contribution to journalArticle

3 Scopus citations

Fluorescent detection of Merlin-deficient Schwann cells and primary human vestibular schwannoma cells using sodium fluorescein

Perez, E. R., Bracho, O., Ein, L., Szczupak, M., Monje, P. V., Fernandez-Valle, C., Alshaiji, A., Ivan, M., Morcos, J., Liu, X. Z., Hoffer, M. E., Eshraghi, A., Angeli, S. I., Telischi, F. F. & Dinh, C. T., Jan 1 2018, In : Otology and Neurotology. 39, 8, p. 1053-1059 7 p.

Research output: Contribution to journalArticle

Genetic basis of hearing loss in Spanish, Hispanic and Latino populations

Mittal, R., Patel, A. P., Nguyen, D., Pan, D. R., Jhaveri, V. M., Rudman, J. R., Dharmaraja, A., Yan, D., Feng, Y., Chapagain, P., Lee, D. J., Blanton, S. H. & Liu, X. Z., Mar 20 2018, In : Gene. 647, p. 297-305 9 p.

Research output: Contribution to journalReview article

4 Scopus citations

Otosclerosis: From Genetics to Molecular Biology

Babcock, T. A. & Liu, X. Z., Apr 1 2018, In : Otolaryngologic Clinics of North America. 51, 2, p. 305-318 14 p.

Research output: Contribution to journalReview article

3 Scopus citations

Precision medicine in hearing loss

Rudman, J. R., Mei, C., Bressler, S. E., Blanton, S. H. & Liu, X. Z., Jan 1 2018, (Accepted/In press) In : Journal of Genetics and Genomics.

Research output: Contribution to journalArticle

4 Scopus citations

Targeted Next-Generation Sequencing of a Deafness Gene Panel (MiamiOtoGenes) Analysis in Families Unsuitable for Linkage Analysis

Shang, H., Yan, D., Tayebi, N., Saeidi, K., Sahebalzamani, A., Feng, Y., Blanton, S. H. & Liu, X. Z., Jan 1 2018, In : BioMed Research International. 2018, 3103986.

Research output: Contribution to journalArticle

6 Scopus citations
2017

A novel frameshift mutation of SMPX causes a rare form of X-linked nonsyndromic hearing loss in a Chinese family

Niu, Z., Feng, Y., Mei, L., Sun, J., Wang, X., Wang, J., Hu, Z., Dong, Y., Chen, H., He, C., Liu, Y., Cai, X., Liu, X. Z. & Jiang, L., May 1 2017, In : PLoS One. 12, 5, e0178384.

Research output: Contribution to journalArticle

8 Scopus citations

Combination therapy with c-Met and Src inhibitors induces caspase-dependent apoptosis of merlin-deficient Schwann cells and suppresses growth of schwannoma cells

Fuse, M. A., Plati, S. K., Burns, S. S., Dinh, C. T., Bracho, O., Yan, D., Mittal, R., Shen, R., Soulakova, J. N., Copik, A. J., Liu, X. Z., Telischi, F. F., Chang, L. S., Franco, M. C. & Fernandez-Valle, C., Nov 1 2017, In : Molecular Cancer Therapeutics. 16, 11, p. 2387-2398 12 p.

Research output: Contribution to journalArticle

5 Scopus citations
5 Scopus citations

Exome sequencing identifies a novel missense mutation of WFS1 as the cause of non-syndromic low-frequency hearing loss in a Chinese family

Niu, Z., Feng, Y., Hu, Z., Li, J., Sun, J., Chen, H., He, C., Wang, X., Jiang, L., Liu, Y., Cai, X., Wang, L., Cai, Y., Liu, X. Z. & Mei, L., Sep 1 2017, In : International Journal of Pediatric Otorhinolaryngology. 100, p. 1-7 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Exome sequencing identifies POU4F3 as the causative gene for a large Chinese family with non-syndromic hearing loss

Cai, X. Z., Li, Y., Xia, L., Peng, Y., He, C. F., Jiang, L., Feng, Y., Xia, K., Liu, X. Z., Mei, L. Y. & Hu, Z. M., Feb 1 2017, In : Journal of Human Genetics. 62, 2, p. 317-320 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Genetic screening revealed usher syndrome in a paediatric Chinese patient

Qu, C., Liang, F., Long, Q., Zhao, M., Shang, H., Fan, L., Wang, L., Yan, D. & Liu, X. Z., Apr 3 2017, In : Hearing, Balance and Communication. 15, 2, p. 98-106 9 p.

Research output: Contribution to journalArticle

Neurotransmitters: The Critical Modulators Regulating Gut–Brain Axis

Mittal, R., Debs, L. H., Patel, A. P., Nguyen, D., Patel, K., O'Connor, G., Grati, M., Mittal, J., Yan, D., Eshraghi, A., Deo, S. K., Daunert, S. & Liu, X. Z., Sep 1 2017, In : Journal of Cellular Physiology. 232, 9, p. 2359-2372 14 p.

Research output: Contribution to journalReview article

72 Scopus citations

Ponatinib promotes a G1 cell-cycle arrest of merlin/NF2-deficient human schwann cells

Petrilli, A. M., Garcia, J., Bott, M., Plati, S. K., Dinh, C. T., Bracho, O. R., Yan, D., Zou, B., Mittal, R., Telischi, F. F., Liu, X. Z., Chang, L. S., Welling, D. B., Copik, A. J. & Fernández-Valle, C., 2017, In : Oncotarget. 8, 19, p. 31666-31681 16 p.

Research output: Contribution to journalArticle

8 Scopus citations

Recent advancements in the regeneration of auditory hair cells and hearing restoration

Mittal, R., Nguyen, D., Patel, A. P., Debs, L. H., Mittal, J., Yan, D., Eshraghi, A., Van De Water, T. R. & Liu, X. Z., Jul 31 2017, In : Frontiers in Molecular Neuroscience. 10, 236.

Research output: Contribution to journalReview article

22 Scopus citations

Role of cyclic nucleotide phosphodiesterases in inner ear and hearing

Mittal, R., Bencie, N., Shaikh, N., Mittal, J., Liu, X. Z. & Eshraghi, A., Nov 9 2017, In : Frontiers in Physiology. 8, NOV, 908.

Research output: Contribution to journalComment/debate

1 Scopus citations

Screening of deafness-causing DNA variants that are common in patients of European ancestry using a microarray-based approach

Yan, D., Xiang, G., Chai, X., Qing, J., Shang, H., Mittal, B. Z. R., Shen, J., Smith, R. J. H., Fan, Y-S., Blanton, S. H., Tekin, M., Morton, C., Xing, W., Cheng, J. & Liu, X. Z., Mar 1 2017, In : PLoS One. 12, 3, e0169219.

Research output: Contribution to journalArticle

13 Scopus citations

Signaling in the Auditory System: Implications in Hair Cell Regeneration and Hearing Function

Mittal, R., Debs, L. H., Nguyen, D., Patel, A. P., Grati, M., Mittal, J., Yan, D., Eshraghi, A. & Liu, X. Z., 2017, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

4 Scopus citations

The advances in hearing rehabilitation and cochlear implants in China

Li, J. N., Chen, S., Zhai, L., Han, D. Y., Eshraghi, A., Feng, Y., Yang, S. M. & Liu, X. Z., Jan 1 2017, In : Ear and Hearing. 38, 6, p. 647-652 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Zika virus: An emerging global health threat

Mittal, R., Nguyen, D., Debs, L. H., Patel, A. P., Liu, G., Jhaveri, V. M., Kay, S. I. S., Mittal, J., Bandstra, E. S., Younis, R. T., Chapagain, P., Jayaweera, D. T. & Liu, X. Z., Dec 8 2017, In : Frontiers in cellular and infection microbiology. 7, DEC, 486.

Research output: Contribution to journalReview article

15 Scopus citations
2016

Abnormal mRNA splicing but normal auditory brainstem response (ABR) in mice with the prestin (SLC26A5) IVS2-2A > G mutation

Zhang, J., Liu, Z., Chang, A., Fang, J., Men, Y., Tian, Y., Ouyang, X., Yan, D., Zhang, A., Sun, X., Tang, J., Liu, X. Z., Zuo, J. & Gao, J., Aug 1 2016, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 790, p. 1-7 7 p.

Research output: Contribution to journalArticle

A mutation in SLC22A4 encoding an organic cation transporter expressed in the cochlea strial endothelium causes human recessive non-syndromic hearing loss DFNB60

Ben Said, M., Grati, M., Ishimoto, T., Zou, B., Chakchouk, I., Ma, Q., Yao, Q., Hammami, B., Yan, D., Mittal, R., Nakamichi, N., Ghorbel, A., Neng, L., Tekin, M., Shi, X. R., Kato, Y., Masmoudi, S., Lu, Z., Hmani, M. & Liu, X. Z., May 1 2016, In : Human Genetics. 135, 5, p. 513-524 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

A next-generation sequencing gene panel (MiamiOtoGenes) for comprehensive analysis of deafness genes

Tekin, D., Yan, D., Bademci, G., Feng, Y., Guo, S., Foster, J., Blanton, S. H., Tekin, M. & Liu, X. Z., Mar 1 2016, In : Hearing Research. 333, p. 179-184 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Characterization of ATPase activity of P2RX2 cation channel

Mittal, R., Grati, M., Sedlacek, M., Yuan, F., Chang, Q., Yan, D., Lin, X., Kachar, B., Farooq, A., Chapagain, P., Zhang, Y. & Liu, X. Z., 2016, In : Frontiers in Physiology. 7, MAY, 186.

Research output: Contribution to journalArticle

4 Scopus citations
9 Scopus citations

CRISPR: a versatile tool for both forward and reverse genetics research

Gurumurthy, C. B., Grati, M., Ohtsuka, M., Schilit, S. L. P., Quadros, R. M. & Liu, X. Z., Sep 1 2016, In : Human Genetics. 135, 9, p. 971-976 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Functional characterization of a novel loss-of-function mutation of PRPS1 related to early-onset progressive nonsyndromic hearing loss in Koreans (DFNX1): Potential implications on future therapeutic intervention

Kim, S. Y., Kim, A. R., Kim, N. K. D., Lee, C., Han, J. H., Kim, M. Y., Jeon, E. H., Park, W. Y., Mittal, R., Yan, D., Liu, X. Z. & Choi, B. Y., Nov 1 2016, In : Journal of Gene Medicine. 18, 11-12, p. 353-358 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Hearing Assessment in Zebrafish during the First Week Postfertilization

Yao, Q., Desmidt, A. A., Tekin, M., Liu, X. Z. & Lu, Z., Apr 1 2016, In : Zebrafish. 13, 2, p. 79-86 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Indispensable Role of Ion Channels and Transporters in the Auditory System

Mittal, R., Aranke, M., Debs, L. H., Nguyen, D., Patel, A. P., Grati, M., Mittal, J., Yan, D., Chapagain, P., Eshraghi, A. & Liu, X. Z., 2016, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

17 Scopus citations