Vladlen Z Slepak

Professor

  • 2974 Citations
1987 …2019
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  • 2 Similar Profiles
GTP-Binding Proteins Medicine & Life Sciences
GTP-Binding Protein Regulators Medicine & Life Sciences
Protein Subunits Medicine & Life Sciences
Proteins Medicine & Life Sciences
RGS Proteins Medicine & Life Sciences
Transducin Medicine & Life Sciences
Carrier Proteins Medicine & Life Sciences
Muscarinic M3 Receptors Medicine & Life Sciences

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Projects 1999 2019

Muscarinic M3 Receptors
RGS Proteins
Hormones
Insulin
Islets of Langerhans
Transducin
Retinal Rod Photoreceptor Cells
Ocular Adaptation
Light
GTP-Binding Proteins
GTP Phosphohydrolases
Phosphoric Diester Hydrolases
GTP-Binding Proteins
Guanosine Triphosphate
GTPase-Activating Proteins
RGS Proteins
G-Protein-Coupled Receptors
GTP-Binding Proteins
GTPase-Activating Proteins
Signal Transduction

Research Output 1987 2019

  • 2974 Citations
  • 78 Article
  • 2 Comment/debate
  • 1 Review article

Inflammasome activation induces pyroptosis in the retina exposed to ocular hypertension injury

Pronin, A., Pham, D., An, W., Dvoriantchikova, G., Reshetnikova, G., Qiao, J., Kozhekbaeva, Z., Reiser, A. E., Slepak, V. Z. & Shestopalov, V. I., Feb 12 2019, In : Frontiers in Molecular Neuroscience. 12, 36.

Research output: Contribution to journalArticle

Open Access
Inflammasomes
Eye Injuries
Ocular Hypertension
Retina
Neuroglia
1 Citation (Scopus)

Pannexin 1 sustains the electrophysiological responsiveness of retinal ganglion cells

Dvoriantchikova, G., Pronin, A., Kurtenbach, S., Toychiev, A., Chou, T. H., Yee, C. W., Prindeville, B., Tayou, J., Porciatti, V., Sagdullaev, B. T., Slepak, V. Z. & Shestopalov, V. I., Dec 1 2018, In : Scientific Reports. 8, 1, 5797.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Retina
Ocular Hypertension
Mechanical Stress
Intraocular Pressure

Correction: Emerging roles of the single EF-hand Ca2+ sensor tescalcin in the regulation of gene expression, cell growth and differentiation [J. Cell Sci, 129, (3533-3540)]

Kolobynina, K. G., Solovyova, V. V., Levay, K., Rizvanov, A. A. & Slepak, V. Z., 2017, In : Journal of Cell Science. 130, 2, p. 521 1 p.

Research output: Contribution to journalComment/debate

EF Hand Motifs
Gene Knockout Techniques
Gene Expression Regulation
Knockout Mice
Cell Differentiation
4 Citations (Scopus)
GTP-Binding Protein Regulators
Muscarinic M3 Receptors
Insulin
RGS Proteins
Cholinergic Agonists
1 Citation (Scopus)

Teaching an old drug new tricks: Agonism, antagonism, and biased signaling of pilocarpine through M3 muscarinic acetylcholine receptor

Pronin, A. N., Wang, Q. & Slepak, V. Z., Nov 1 2017, In : Molecular Pharmacology. 92, 5, p. 601-612 12 p.

Research output: Contribution to journalArticle

Pilocarpine
Muscarinic Receptors
Teaching
Carbachol
Pharmaceutical Preparations