Projects per year
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- 8 Similar Profiles
Interleukin-2
Medicine & Life Sciences
Interleukin-2 Receptors
Medicine & Life Sciences
T-Lymphocytes
Medicine & Life Sciences
Regulatory T-Lymphocytes
Medicine & Life Sciences
B-Lymphocytes
Medicine & Life Sciences
Interleukin-7
Medicine & Life Sciences
Interleukin-15
Medicine & Life Sciences
Monoclonal Antibodies
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 1987 2023
Regulatory T-Lymphocytes
Interleukin-2
Autoimmune Diseases
Eragrostis
Autoimmunity
Low-dose IL-2 in Established T1D
Malek, T., Skyler, J. S. & Pugliese, A.
8/15/17 → 7/31/23
Project: Research project
Type 1 Diabetes Mellitus
Interleukin-2
Insulin
Regulatory T-Lymphocytes
Safety
Interleukin-2
Immunity
Neoplasms
Cancer Vaccines
T-Lymphocytes
Type 1 Diabetes Mellitus
Interleukin-2
Inbred NOD Mouse
Autoimmune Diseases
Homeostasis
Induction of Tumor Immunity by Secreted HSP-gp96
Podack, E. R., Rosenblatt, J. D., Malek, T., Adkins, R., Cray, C. & Deyev, V.
12/1/06 → 3/31/13
Project: Research project
Immunity
Neoplasms
B-Lymphocytes
Heat-Shock Proteins
Chemokines
Research Output 1974 2019
CD25 and protein phosphatase 2A cooperate to enhance IL-2R signaling in human regulatory T cells
Ding, Y., Yu, A., Tsokos, G. C. & Malek, T., Jan 1 2019, In : Journal of Immunology. 203, 1, p. 93-104 12 p.Research output: Contribution to journal › Article
Protein Phosphatase 2
Regulatory T-Lymphocytes
Interleukin-2
Catalytic Domain
Phosphorylation
1
Citation
(Scopus)
Essential and non-overlapping IL-2Rα-dependent processes for thymic development and peripheral homeostasis of regulatory T cells
Toomer, K. H., Lui, J. B., Altman, N. H., Ban, Y., Chen, X. & Malek, T., Dec 1 2019, In : Nature communications. 10, 1, 1037.Research output: Contribution to journal › Article
homeostasis
T-cells
Regulatory T-Lymphocytes
Interleukin-2
Homeostasis
8
Citations
(Scopus)
Cytokine signaling in the development and homeostasis of regulatory T cells
Toomer, K. H. & Malek, T., Mar 1 2018, In : Cold Spring Harbor perspectives in biology. 10, 3, a028597.Research output: Contribution to journal › Review article
T-cells
Regulatory T-Lymphocytes
Homeostasis
Cytokines
Interleukin-2
10
Citations
(Scopus)
IL-2/CD25: A long-acting fusion protein that promotes immune tolerance by selectively targeting the IL-2 receptor on regulatory t cells
Ward, N. C., Yu, A., Moro, A., Ban, Y., Chen, X., Hsiung, S., Keegan, J., Arbanas, J. M., Loubeau, M., Thankappan, A., Yamniuk, A. P., Davis, J. H., Struthers, M. & Malek, T., Nov 1 2018, In : Journal of Immunology. 201, 9, p. 2579-2592 14 p.Research output: Contribution to journal › Article
Immune Tolerance
Interleukin-2 Receptors
Interleukin-2
Proteins
Autoimmunity
26
Citations
(Scopus)
Regulatory T cells in the treatment of disease
Sharabi, A., Tsokos, M. G., Ding, Y., Malek, T., Klatzmann, D. & Tsokos, G. C., Oct 30 2018, In : Nature Reviews Drug Discovery. 17, 11, p. 823-844 22 p.Research output: Contribution to journal › Review article
Regulatory T-Lymphocytes
Therapeutics
Neoplasms
Immunosuppressive Agents
Autoimmunity