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Thomas Malek

Professor

  • 10192 Citations
1974 …2024

Research output per year

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Projects

IL-2R-dependent mechanisms in regulation of Treg homeostasis and autoimmunity

Malek, T.

National Institutes of Health

12/10/19 → 11/30/24

Project: Research project

    • Low dose IL-2 and human regulatory T cells

    Malek, T.

    National Institutes of Health

    11/21/17 → 11/30/22

    Project: Research project

    • Low-dose IL-2 in Established T1D

    Malek, T., Skyler, J. S. & Pugliese, A.

    National Institutes of Health

    8/15/17 → 7/31/23

    Project: Research project

    • A novel IL-2 biologic and tumor immunity

    Malek, T.

    National Institutes of Health

    12/1/15 → 11/30/18

    Project: Research project

    • IL-2-dependent mechanisms in T1D

    Malek, T.

    National Institutes of Health

    9/27/12 → 8/31/17

    Project: Research project

    • Research Output

    • 10192 Citations
    • 163 Article
    • 2 Review article

    CD25 and protein phosphatase 2A cooperate to enhance IL-2R signaling in human regulatory T cells

    Ding, Y., Yu, A., Tsokos, G. C. & Malek, T., Jan 1 2019, In : Journal of Immunology. 203, 1, p. 93-104 12 p.

    Research output: Contribution to journal › Article

    • Essential and non-overlapping IL-2Rα-dependent processes for thymic development and peripheral homeostasis of regulatory T cells

    Toomer, K. H., Lui, J. B., Altman, N. H., Ban, Y., Chen, X. & Malek, T., Dec 1 2019, In : Nature communications. 10, 1, 1037.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Cytokine signaling in the development and homeostasis of regulatory T cells

    Toomer, K. H. & Malek, T., Mar 1 2018, In : Cold Spring Harbor perspectives in biology. 10, 3, a028597.

    Research output: Contribution to journal › Review article

    • 9 Scopus citations

    IL-2/CD25: A long-acting fusion protein that promotes immune tolerance by selectively targeting the IL-2 receptor on regulatory t cells

    Ward, N. C., Yu, A., Moro, A., Ban, Y., Chen, X., Hsiung, S., Keegan, J., Arbanas, J. M., Loubeau, M., Thankappan, A., Yamniuk, A. P., Davis, J. H., Struthers, M. & Malek, T., Nov 1 2018, In : Journal of Immunology. 201, 9, p. 2579-2592 14 p.

    Research output: Contribution to journal › Article

    • 11 Scopus citations

    Regulatory T cells in the treatment of disease

    Sharabi, A., Tsokos, M. G., Ding, Y., Malek, T., Klatzmann, D. & Tsokos, G. C., Oct 30 2018, In : Nature Reviews Drug Discovery. 17, 11, p. 823-844 22 p.

    Research output: Contribution to journal › Review article

    • 36 Scopus citations