Projects per year
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- 9 Similar Profiles
Interleukin-2
Medicine & Life Sciences
Interleukin-2 Receptors
Medicine & Life Sciences
T-Lymphocytes
Medicine & Life Sciences
Regulatory T-Lymphocytes
Medicine & Life Sciences
B-Lymphocytes
Medicine & Life Sciences
Interleukin-7
Medicine & Life Sciences
Interleukin-15
Medicine & Life Sciences
Monoclonal Antibodies
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 1987 2022
Low dose IL-2 and human regulatory T cells
11/21/17 → 11/30/22
Project: Research project › Research Project
Regulatory T-Lymphocytes
Interleukin-2
Autoimmune Diseases
Eragrostis
Autoimmunity
A novel IL-2 biologic and tumor immunity
12/1/15 → 11/30/18
Project: Research project › Exploratory/Developmental Grants
Interleukin-2
Immunity
Neoplasms
Cancer Vaccines
T-Lymphocytes
Type 1 Diabetes Mellitus
Interleukin-2
Inbred NOD Mouse
Autoimmune Diseases
Homeostasis
Induction of Tumor Immunity by Secreted HSP-gp96
Podack, E. R., Rosenblatt, J. D., Malek, T., Adkins, R., Cray, C. & Deyev, V.
12/1/06 → 3/31/13
Project: Research project › Research Program Projects
Immunity
Neoplasms
B-Lymphocytes
Heat-Shock Proteins
Chemokines
Immunobiology of CD4+CD25+ T regulatory cells
5/1/04 → 11/30/16
Project: Research project › Research Project
Regulatory T-Lymphocytes
Autoimmunity
Self Tolerance
Autoimmune Diseases
Hematopoietic Stem Cell Transplantation
Research Output 1974 2018
5
Citations
Cytokine signaling in the development and homeostasis of regulatory T cells
Toomer, K. H. & Malek, T., Mar 1 2018, In : Cold Spring Harbor perspectives in biology. 10, 3, a028597.Research output: Contribution to journal › Review article
T-cells
Regulatory T-Lymphocytes
Homeostasis
Cytokines
Interleukin-2
IL-2/CD25: A long-acting fusion protein that promotes immune tolerance by selectively targeting the IL-2 receptor on regulatory t cells
Ward, N. C., Yu, A., Moro, A., Ban, Y., Chen, X., Hsiung, S., Keegan, J., Arbanas, J. M., Loubeau, M., Thankappan, A., Yamniuk, A. P., Davis, J. H., Struthers, M. & Malek, T., Nov 1 2018, In : Journal of Immunology. 201, 9, p. 2579-2592 14 p.Research output: Contribution to journal › Article
Immune Tolerance
Interleukin-2 Receptors
Interleukin-2
Proteins
Autoimmunity
Regulatory T cells in the treatment of disease
Sharabi, A., Tsokos, M. G., Ding, Y., Malek, T., Klatzmann, D. & Tsokos, G. C., Oct 30 2018, In : Nature Reviews Drug Discovery. 17, 11, p. 823-844 22 p.Research output: Contribution to journal › Review article
Regulatory T-Lymphocytes
Therapeutics
Neoplasms
Immunosuppressive Agents
Autoimmunity
4
Citations
Altered homeostasis and development of regulatory T cell subsets represent an IL-2R–dependent risk for diabetes in NOD mice
Dwyer, C. J., Bayer, A. L., Fotino, C., Yu, L., Cabello-Kindelan, C., Ward, N. C., Toomer, K. H., Chen, Z. & Malek, T., Dec 19 2017, In : Science Signaling. 10, 510, eaam9563.Research output: Contribution to journal › Article
Inbred NOD Mouse
T-cells
T-Lymphocyte Subsets
Regulatory T-Lymphocytes
Medical problems
2
Citations
The lower limit of regulatory CD4+ Foxp3++ TCRβ repertoire diversity required to control autoimmunity
Yu, A., Dee, M. J., Adeegbe, D., Dwyer, C. J., Altman, N. H. & Malek, T., Apr 15 2017, In : Journal of Immunology. 198, 8, p. 3127-3135 9 p.Research output: Contribution to journal › Article
Autoimmunity
T-Lymphocytes
Self Tolerance
Autoantigens
Regulatory T-Lymphocytes