Projects per year
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- 3 Similar Profiles
Deoxyglucose
Medicine & Life Sciences
Rhodamine 123
Medicine & Life Sciences
Doxorubicin
Medicine & Life Sciences
Cells
Chemical Compounds
Neoplasms
Medicine & Life Sciences
Multiple Drug Resistance
Medicine & Life Sciences
Cell Line
Medicine & Life Sciences
Tumors
Chemical Compounds
Network
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Projects 1983 2012
- 1 Finished
DRUG SELECTIVITY IN CARDIAC AND MDR TUMOR CELLS
7/1/83 → 6/30/12
Project: Research project › Research Project
Glycolysis
Neoplasms
Anthracyclines
Glycosylation
Deoxyglucose
Research Output 1971 2016
10
Citations
2-deoxy-glucose downregulates endothelial AKT and ERK via interference with N-linked glycosylation, induction of endoplasmic reticulum stress, and GSK3β activation
Kovacs, K., Decatur, C., Toro, M., Pham, D. G., Liu, H., Jing, Y., Murray, T. G., Lampidis, T. & Merchan, J. R., Feb 1 2016, In : Molecular Cancer Therapeutics. 15, 2, p. 264-275 12 p.Research output: Contribution to journal › Article
Endoplasmic Reticulum Stress
Deoxyglucose
Glycosylation
Down-Regulation
Endothelial Cells
2
Citations
Combining 2-deoxy-D-glucose with fenofibrate leads to tumor cell death mediated by simultaneous induction of energy and ER stress
Liu, H., Kurtoglu, M., León-Annicchiarico, C. L., Munoz-Pinedo, C., Barredo, J., Leclerc, G., Merchan, J. R., Liu, X. & Lampidis, T., 2016, In : Oncotarget. 7, 24, p. 36461-36473 13 p.Research output: Contribution to journal › Article
Fenofibrate
Endoplasmic Reticulum Stress
Deoxyglucose
Cell Death
Glucose
11
Citations
ATF4 mediates necrosis induced by glucose deprivation and apoptosis induced by 2-deoxyglucose in the same cells
Leõn-Annicchiarico, C. L., Ramírez-Peinado, S., Domínguez-Villanueva, D., Gonsberg, A., Lampidis, T. & Muñoz-Pinedo, C., Sep 1 2015, In : FEBS Journal. 282, 18, p. 3647-3658 12 p.Research output: Contribution to journal › Article
Deoxyglucose
Necrosis
Apoptosis
Glucose
Cell death
4
Citations
Mcl-1 downregulation leads to the heightened sensitivity exhibited by BCR-ABL positive ALL to induction of energy and ER-stress
Leclerc, G. J., DeSalvo, J., Du, J., Gao, N., Leclerc, G. M., Lehrman, M. A., Lampidis, T. & Barredo, J., May 13 2015, (Accepted/In press) In : Leukemia Research.Research output: Contribution to journal › Article
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Down-Regulation
AMP-Activated Protein Kinases
MAP Kinase Signaling System
Glucose
7
Citations
Increased sensitivity to glucose starvation correlates with downregulation of glycogen phosphorylase isoform PYGB in tumor cell lines resistant to 2-deoxy-d-glucose
Philips, K. B., Kurtoglu, M., Leung, H. J., Liu, H., Gao, N., Lehrman, M. A., Murray, T. G. & Lampidis, T., Jan 1 2014, In : Cancer Chemotherapy and Pharmacology. 73, 2, p. 349-361 13 p.Research output: Contribution to journal › Article
Glycogen Phosphorylase
Starvation
Tumor Cell Line
Tumors
Protein Isoforms