Stephen D Nimer, M.D.

Professor

  • 18263 Citations
1975 …2022
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Acute Myeloid Leukemia Medicine & Life Sciences
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Projects 1978 2022

Acute Myeloid Leukemia
Acetylation
Lysine
Proteins
Leukemia
Polycomb-Group Proteins
Neoplasms
Proteins
Genes
Hematologic Neoplasms
Cholecalciferol
Cell Differentiation
Myeloid Cells
Nuclear Receptor Coactivators
Genes
Hematopoietic Stem Cells
Cell Cycle
Natural Killer Cells
Cell Aging
Innate Immunity
Colony-Stimulating Factors
Intercellular Signaling Peptides and Proteins
Myeloid Leukemia
T-Lymphocytes
Acute Myeloid Leukemia

Research Output 1975 2019

ASXL1 alteration cooperates with JAK2V617F to accelerate myelofibrosis

Guo, Y., Zhou, Y., Yamatomo, S., Yang, H., Zhang, P., Chen, S., Nimer, S. D., Zhao, Z. J., Xu, M., Bai, J. & Yang, F-C., Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Primary Myelofibrosis

Destabilization of AETFC through C/EBPα-mediated repression of LYL1 contributes to t(8;21) leukemic cell differentiation

Zhang, M. M., Liu, N., Zhang, Y. L., Rong, B., Wang, X. L., Xu, C. H., Xie, Y. Y., Shen, S., Zhu, J., Nimer, S. D., Chen, Z., Chen, S. J., Roeder, R. G., Lan, F., Wang, L., Huang, Q. H. & Sun, X. J., Jan 1 2019, In : Leukemia.

Research output: Contribution to journalLetter

Cell Differentiation

Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis

Liu, N., Song, J., Xie, Y., Wang, X. L., Rong, B., Man, N., Zhang, M. M., Zhang, Q., Gao, F. F., Du, M. R., Zhang, Y., Shen, J., Xu, C. H., Hu, C. L., Wu, J. C., Liu, P., Zhang, Y. L., Xie, Y. Y., Liu, P., Huang, J. Y. & 9 othersHuang, Q. H., Lan, F., Shen, S., Nimer, S. D., Chen, Z., Chen, S. J., Roeder, R. G., Wang, L. & Sun, X. J., Jan 15 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 3, p. 890-899 10 p.

Research output: Contribution to journalArticle

Fusion Oncogene Proteins
Core Binding Factor Alpha 2 Subunit
Transcription Factor 7-Like 2 Protein
Basic Helix-Loop-Helix Transcription Factors
Tumor Cell Line

Erratum: CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis (Cancer Cell (2018) 33(6) (1111–1127.e5), (S1535610818302216), (10.1016/j.ccell.2018.05.007))

Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., Bilbao, D., Stathias, V., Jermakowicz, A. M., Duffort, S., Tadi, M., Blumenthal, E., Newman, S., Vu, L., Xu, Y., Liu, F., Schuerer, S. C., McCabe, M. T., Kruger, R. G., Xu, M. & 5 othersYang, F-C., Tenen, D. G., Watts, J., Vega, F. & Nimer, S. D., Jan 14 2019, In : Cancer Cell. 35, 1, 1 p.

Research output: Contribution to journalComment/debate

Hematopoiesis
Names
Neoplasms
coactivator-associated arginine methyltransferase 1
1 Citation (Scopus)

CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis

Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., Bilbao, D., Stathais, V., McGrew-Jermacowicz, A., Duffort, S., Tadi, M., Blumenthal, E., Newman, S., Vu, L., Xu, Y., Liu, F., Schuerer, S. C., McCabe, M. T., Kruger, R. G., Xu, M. & 5 othersYang, F-C., Tenen, D., Watts, J., Vega, F. & Nimer, S. D., Jun 11 2018, In : Cancer Cell. 33, 6, p. 1111-1127.e5

Research output: Contribution to journalArticle

Hematopoiesis
Acute Myeloid Leukemia
Cell Cycle
Protein-Arginine N-Methyltransferases
Apoptosis