Stephan C Schuerer

Associate Professor

  • 3842 Citations
1996 …2023

Research output per year

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Research Output

2020

Identification of DOT1L inhibitors by structure-based virtual screening adapted from a nucleoside-focused library

Gibbons, G. S., Chakraborty, A., Grigsby, S. M., Umeano, A. C., Liao, C., Moukha-Chafiq, O., Pathak, V., Mathew, B., Lee, Y. T., Dou, Y., Schürer, S. C., Reynolds, R. C., Snowden, T. S. & Nikolovska-Coleska, Z., Mar 1 2020, In : European Journal of Medicinal Chemistry. 189, 112023.

Research output: Contribution to journalArticle

LINCS Data Portal 2.0: next generation access point for perturbation-response signatures

Stathias, V., Turner, J., Koleti, A., Vidovic, D., Cooper, D., Fazel-Najafabadi, M., Pilarczyk, M., Terryn, R., Chung, C., Umeano, A., Clarke, D. J. B., Lachmann, A., Evangelista, J. E., Ma'ayan, A., Medvedovic, M. & Schürer, S. C., Jan 8 2020, In : Nucleic acids research. 48, D1, p. D431-D439

Research output: Contribution to journalArticle

Open Access

Machine and deep learning approaches for cancer drug repurposing

Issa, N. T., Stathias, V., Schürer, S. & Dakshanamurthy, S., Jan 1 2020, (Accepted/In press) In : Seminars in Cancer Biology.

Research output: Contribution to journalReview article

2019

A Gene Family-led Meta-Analysis of Drug-Target Interactions

Cheng, Q., Mehta, S. & Schuerer, S. C., Jan 21 2019, Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018. Schmidt, H., Griol, D., Wang, H., Baumbach, J., Zheng, H., Callejas, Z., Hu, X., Dickerson, J. & Zhang, L. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 1618-1623 6 p. 8621087. (Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

DrugCentral 2018: an update

Ursu, O., Holmes, J., Bologa, C. G., Yang, J. J., Mathias, S. L., Stathias, V., Nguyen, D. T., Schuerer, S. C. & Oprea, T., Jan 8 2019, In : Nucleic Acids Research. 47, D1, p. D963-D970

Research output: Contribution to journalArticle

11 Scopus citations

Erratum: CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis (Cancer Cell (2018) 33(6) (1111–1127.e5), (S1535610818302216), (10.1016/j.ccell.2018.05.007))

Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., Bilbao, D., Stathias, V., Jermakowicz, A. M., Duffort, S., Tadi, M., Blumenthal, E., Newman, S., Vu, L., Xu, Y., Liu, F., Schurer, S. C., McCabe, M. T., Kruger, R. G., Xu, M. & 5 others, Yang, F. C., Tenen, D. G., Watts, J., Vega, F. & Nimer, S. D., Jan 14 2019, In : Cancer Cell. 35, 1, 1 p.

Research output: Contribution to journalComment/debate

FAIRshake: Toolkit to Evaluate the FAIRness of Research Digital Resources

Clarke, D. J. B., Wang, L., Jones, A., Wojciechowicz, M. L., Torre, D., Jagodnik, K. M., Jenkins, S. L., McQuilton, P., Flamholz, Z., Silverstein, M. C., Schilder, B. M., Robasky, K., Castillo, C., Idaszak, R., Ahalt, S. C., Williams, J., Schurer, S., Cooper, D. J., de Miranda Azevedo, R., Klenk, J. A. & 14 others, Haendel, M. A., Nedzel, J., Avillach, P., Shimoyama, M. E., Harris, R. M., Gamble, M., Poten, R., Charbonneau, A. L., Larkin, J., Brown, C. T., Bonazzi, V. R., Dumontier, M. J., Sansone, S. A. & Ma'ayan, A., Nov 27 2019, In : Cell Systems. 9, 5, p. 417-421 5 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

How to develop a drug target ontology: KNowledge acquisition and representation methodology (KNARM)

Küçük McGinty, H., Visser, U. E. & Schuerer, S. C., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 49-69 21 p. (Methods in Molecular Biology; vol. 1939).

Research output: Chapter in Book/Report/Conference proceedingChapter

Open Access
1 Scopus citations

Novel Curcumin inspired bis-chalcone promotes endoplasmic reticulum stress and glioblastoma neurosphere cell death

Sansalone, L., Veliz, E. A., Myrthil, N. G., Stathias, V., Walters, W., Torrens, I. I., Schürer, S. C., Vanni, S., Leblanc, R. M. & Graham, R. M., Mar 1 2019, In : Cancers. 11, 3, 357.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

OSCI: Standardized stem cell ontology representation and use cases for stem cell investigation

He, Y., Duncan, W. D., Cooper, D. J., Hansen, J., Iyengar, R., Ong, E., Walker, K., Tibi, O., Smith, S., Serra, L. M., Zheng, J., Sarntivijai, S., Schuerer, S. C., O'shea, K. S. & Diehl, A. D., Apr 25 2019, In : BMC Bioinformatics. 20, 180.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Research Techniques Made Simple: Molecular Docking in Dermatology - A Foray into In Silico Drug Discovery

Issa, N. T., Badiavas, E. V. & Schürer, S., Dec 2019, In : Journal of Investigative Dermatology. 139, 12, p. 2400-2408.e1

Research output: Contribution to journalShort survey

Open Access

Use of machine learning to identify novel, behaviorally active antagonists of the insect odorant receptor co-receptor (Orco) subunit

Kepchia, D., Xu, P., Terryn, R., Castro, A., Schürer, S. C., Leal, W. S. & Luetje, C. W., Dec 1 2019, In : Scientific reports. 9, 1, 4055.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2018

CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis

Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., Bilbao, D., Stathais, V., McGrew-Jermacowicz, A., Duffort, S., Tadi, M., Blumenthal, E., Newman, S., Vu, L., Xu, Y., Liu, F., Schuerer, S. C., McCabe, M. T., Kruger, R. G., Xu, M. & 5 others, Yang, F-C., Tenen, D., Watts, J., Vega, F. & Nimer, S. D., Jun 11 2018, In : Cancer Cell. 33, 6, p. 1111-1127.e5

Research output: Contribution to journalArticle

8 Scopus citations

Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: Integrated access to diverse large-scale cellular perturbation response data

Koleti, A., Terryn, R., Stathias, V., Chung, C., Cooper, D. J., Turner, J. P., VidoviÄ ‡, D., Forlin, M., Kelley, T. T., D'Urso, A., Allen, B. K., Torre, D., Jagodnik, K. M., Wang, L., Jenkins, S. L., Mader, C., Niu, W., Fazel, M., Mahi, N., Pilarczyk, M. & 9 others, Clark, N., Shamsaei, B., Meller, J., Vasiliauskas, J., Reichard, J., Medvedovic, M., Ma'Ayan, A., Pillai, A. & Schürer, S. C., Jan 1 2018, In : Nucleic Acids Research. 46, D1, p. D558-D566

Research output: Contribution to journalArticle

34 Scopus citations

Drug and disease signature integration identifies synergistic combinations in glioblastoma

Stathias, V., Jermakowicz, A. M., Maloof, M. E., Forlin, M., Walters, W., Suter, R. K., Durante, M. A., Williams, S. L., Harbour, J. W., Volmar, C. H., Lyons, N. J., Wahlestedt, C., Graham, R. M., Ivan, M. E., Komotar, R. J., Sarkaria, J. N., Subramanian, A., Golub, T. R., Schürer, S. C. & Ayad, N. G., Dec 1 2018, In : Nature Communications. 9, 1, 5315.

Research output: Contribution to journalArticle

9 Scopus citations

Drug repositioning in glioblastoma: A pathway perspective

Tan, S. K., Jermakowicz, A., Mookhtiar, A. K., Nemeroff, C., Schuerer, S. C. & Ayad, N., Mar 16 2018, In : Frontiers in Pharmacology. 9, MAR, 218.

Research output: Contribution to journalReview article

17 Scopus citations

Erratum: CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis (Cancer Cell (2018) 33(6) (1111–1127.e5), (S1535610818302216) (10.1016/j.ccell.2018.05.007))

Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., Bilbao, D., Stathias, V., McGrew-Jermacowicz, A., Duffort, S., Tadi, M., Blumenthal, E., Newman, S., Vu, L., Xu, Y., Liu, F., Schurer, S. C., McCabe, M. T., Kruger, R. G., Xu, M. & 5 others, Yang, F. C., Tenen, D., Watts, J., Vega, F. & Nimer, S. D., Nov 12 2018, In : Cancer Cell. 34, 5, 1 p.

Research output: Contribution to journalComment/debate

Erratum: Unexplored therapeutic opportunities in the human genome (Nature reviews. Drug discovery (2018) 17 5 (317-332))

Oprea, T. I., Bologa, C. G., Brunak, S., Campbell, A., Gan, G. N., Gaulton, A., Gomez, S. M., Guha, R., Hersey, A., Holmes, J., Jadhav, A., Jensen, L. J., Johnson, G. L., Karlson, A., Leach, A. R., Ma'ayan, A., Malovannaya, A., Mani, S., Mathias, S. L., McManus, M. T. & 21 others, Meehan, T. F., von Mering, C., Muthas, D., Nguyen, D. T., Overington, J. P., Papadatos, G., Qin, J., Reich, C., Roth, B. L., Schürer, S. C., Simeonov, A., Sklar, L. A., Southall, N., Tomita, S., Tudose, I., Ursu, O., Vidovic, D., Waller, A., Westergaard, D., Yang, J. J. & Zahoránszky-Köhalmi, G., May 1 2018, In : Nature reviews. Drug discovery. 17, 5, 1 p.

Research output: Contribution to journalComment/debate

Open Access
8 Scopus citations

Far away from the lamppost

Oprea, T. I., Jan, L., Johnson, G. L., Roth, B. L., Ma’ayan, A., Schuerer, S. C., Shoichet, B. K., Sklar, L. A. & McManus, M. T., Dec 1 2018, In : PLoS Biology. 16, 12, e3000067.

Research output: Contribution to journalArticle

4 Scopus citations

Polypharmacology or promiscuity? Structural interactions of resveratrol with its bandwagon of targets

Saqib, U., Kelley, T. T., Panguluri, S. K., Liu, D., Savai, R., Baig, M. S. & Schuerer, S. C., Oct 24 2018, In : Frontiers in Pharmacology. 9, OCT, 1201.

Research output: Contribution to journalArticle

10 Scopus citations

Sustainable data and metadata management at the BD2K-LINCS Data coordination and integration center

Stathias, V., Koleti, A., Vidovic, D., Cooper, D. J., Jagodnik, K. M., Terryn, R., Forlin, M., Chung, C., Torre, D., Ayad, N., Medvedovic, M., Ma'Ayan, A., Pillai, A. & Schuerer, S. C., Jun 19 2018, In : Scientific data. 5, 180117.

Research output: Contribution to journalArticle

6 Scopus citations

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

Keenan, A. B., Jenkins, S. L., Jagodnik, K. M., Koplev, S., He, E., Torre, D., Wang, Z., Dohlman, A. B., Silverstein, M. C., Lachmann, A., Kuleshov, M. V., Ma'ayan, A., Stathias, V., Terryn, R., Cooper, D., Forlin, M., Koleti, A., Vidovic, D., Chung, C., Schuerer, S. C. & 87 others, Vasiliauskas, J., Pilarczyk, M., Shamsaei, B., Fazel, M., Ren, Y., Niu, W., Clark, N. A., White, S., Mahi, N., Zhang, L., Kouril, M., Reichard, J. F., Sivaganesan, S., Medvedovic, M., Meller, J., Koch, R. J., Birtwistle, M. R., Iyengar, R., Sobie, E. A., Azeloglu, E. U., Kaye, J., Osterloh, J., Haston, K., Kalra, J., Finkbiener, S., Li, J., Milani, P., Adam, M., Escalante-Chong, R., Sachs, K., Lenail, A., Ramamoorthy, D., Fraenkel, E., Daigle, G., Hussain, U., Coye, A., Rothstein, J., Sareen, D., Ornelas, L., Banuelos, M., Mandefro, B., Ho, R., Svendsen, C. N., Lim, R. G., Stocksdale, J., Casale, M. S., Thompson, T. G., Wu, J., Thompson, L. M., Dardov, V., Venkatraman, V., Matlock, A., Van Eyk, J. E., Jaffe, J. D., Papanastasiou, M., Subramanian, A., Golub, T. R., Erickson, S. D., Fallahi-Sichani, M., Hafner, M., Gray, N. S., Lin, J. R., Mills, C. E., Muhlich, J. L., Niepel, M., Shamu, C. E., Williams, E. H., Wrobel, D., Sorger, P. K., Heiser, L. M., Gray, J. W., Korkola, J. E., Mills, G. B., LaBarge, M., Feiler, H. S., Dane, M. A., Bucher, E., Nederlof, M., Sudar, D., Gross, S., Kilburn, D. F., Smith, R., Devlin, K., Margolis, R., Derr, L., Lee, A. & Pillai, A., Jan 24 2018, In : Cell Systems. 6, 1, p. 13-24 12 p.

Research output: Contribution to journalReview article

74 Scopus citations

Unexplored therapeutic opportunities in the human genome

Oprea, T. I., Bologa, C. G., Brunak, S., Campbell, A., Gan, G. N., Gaulton, A., Gomez, S. M., Guha, R., Hersey, A., Holmes, J., Jadhav, A., Jensen, L. J., Johnson, G. L., Karlson, A., Leach, A. R., Ma'ayan, A., Malovannaya, A., Mani, S., Mathias, S. L., McManus, M. T. & 21 others, Meehan, T. F., Von Mering, C., Muthas, D., Nguyen, D. T., Overington, J. P., Papadatos, G., Qin, J., Reich, C., Roth, B. L., Schürer, S. C., Simeonov, A., Sklar, L. A., Southall, N., Tomita, S., Tudose, I., Ursu, O., Vidović, D., Waller, A., Westergaard, D., Yang, J. J. & Zahoránszky-Köhalmi, G., Apr 27 2018, In : Nature Reviews Drug Discovery. 17, 5, p. 317-332 16 p.

Research output: Contribution to journalReview article

59 Scopus citations
2017

Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop

Jagodnik, K. M., Koplev, S., Jenkins, S. L., Ohno-Machado, L., Paten, B., Schurer, S. C., Dumontier, M., Verborgh, R., Bui, A., Ping, P., McKenna, N. J., Madduri, R., Pillai, A. & Ma'ayan, A., Jul 2017, In : Journal of biomedical informatics. 71, p. 49-57 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Drug target ontology to classify and integrate drug discovery data

Lin, Y., Mehta, S., Küçük-McGinty, H., Turner, J. P., Vidovic, D., Forlin, M., Koleti, A., Nguyen, D. T., Jensen, L. J., Guha, R., Mathias, S. L., Ursu, O., Stathias, V., Duan, J., Nabizadeh, N., Chung, C., Mader, C., Visser, U., Yang, J. J., Bologa, C. G. & 2 others, Oprea, T. I. & Schürer, S. C., Nov 9 2017, In : Journal of Biomedical Semantics. 8, 1, 50.

Research output: Contribution to journalArticle

9 Scopus citations

From flamingo dance to (desirable) drug discovery: A nature-inspired approach

Sánchez-Rodríguez, A., Pérez-Castillo, Y., Schuerer, S. C., Nicolotti, O., Mangiatordi, G. F., Borges, F., Cordeiro, M. N. D. S., Tejera, E., Medina-Franco, J. L. & Cruz-Monteagudo, M., 2017, (Accepted/In press) In : Drug Discovery Today.

Research output: Contribution to journalArticle

6 Scopus citations

Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations

Allen, B. K., Mehta, S., Ember, S. W. J., Zhu, J. Y., Schönbrunn, E., Ayad, N. & Schuerer, S. C., Jan 1 2017, In : ACS Omega. 2, 8, p. 4760-4771 12 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Learning reference-enriched approach towards large scale active ontology alignment and integration

Cheng, Q., Ursu, O., Oprea, T. I. & Schuerer, S. C., Dec 15 2017, Proceedings - 2017 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2017. Institute of Electrical and Electronics Engineers Inc., Vol. 2017-January. p. 1658-1663 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Ontological representation, integration, and analysis of LINCS cell line cells and their cellular responses

Ong, E., Xie, J., Ni, Z., Liu, Q., Sarntivijai, S., Lin, Y., Cooper, D., Terryn, R., Stathias, V., Chung, C., Schuerer, S. C. & He, Y., Dec 21 2017, In : BMC Bioinformatics. 18, 556.

Research output: Contribution to journalArticle

5 Scopus citations

Pharos: Collating protein information to shed light on the druggable genome

Nguyen, D. T., Mathias, S., Bologa, C., Brunak, S., Fernandez, N., Gaulton, A., Hersey, A., Holmes, J., Jensen, L. J., Karlsson, A., Liu, G., Ma'ayan, A., Mandava, G., Mani, S., Mehta, S., Overington, J., Patel, J., Rouillard, A. D., Schürer, S., Sheils, T. & 10 others, Simeonov, A., Sklar, L. A., Southall, N., Ursu, O., Vidovic, D., Waller, A., Yang, J., Jadhav, A., Oprea, T. I. & Guha, R., Jan 1 2017, In : Nucleic acids research. 45, D1, p. D995-D1002

Research output: Contribution to journalArticle

54 Scopus citations

Systemic QSAR and phenotypic virtual screening: chasing butterflies in drug discovery

Cruz-Monteagudo, M., Schürer, S., Tejera, E., Pérez-Castillo, Y., Medina-Franco, J. L., Sánchez-Rodríguez, A. & Borges, F., Jul 2017, In : Drug Discovery Today. 22, 7, p. 994-1007 14 p.

Research output: Contribution to journalReview article

12 Scopus citations

The ontology reference model for visual selectivity analysis in drug-target interactions

Cheng, Q., Lopez, F. A., Duran, C., Camarillo, C., Oprea, T. I. & Schuerer, S. C., Dec 15 2017, Proceedings - 2017 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2017. Institute of Electrical and Electronics Engineers Inc., Vol. 2017-January. p. 2091-2097 7 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

TIN-X: target importance and novelty explorer

Cannon, D. C., Yang, J. J., Mathias, S. L., Ursu, O., Mani, S., Waller, A., Schuerer, S. C., Jensen, L. J., Sklar, L. A., Bologa, C. G. & Oprea, T. I., Aug 15 2017, In : Bioinformatics (Oxford, England). 33, 16, p. 2601-2603 3 p.

Research output: Contribution to journalArticle

6 Scopus citations
2016

Building concordant ontologies for drug discovery

Küçük-McGinty, H., Mehta, S., Lin, Y., Nabizadeh, N., Stathias, V., Vidovic, D., Koleti, A., Mader, C., Duan, J., Visser, U. E. & Schuerer, S. C., 2016, In : CEUR Workshop Proceedings. 1747

Research output: Contribution to journalArticle

High quality, small molecule-activity datasets for kinase research [version 1; referees: 2 approved]

Sharma, R., Schuerer, S. C. & Muskal, S. M., 2016, In : F1000Research. 5, 1366.

Research output: Contribution to journalArticle

High quality, small molecule-activity datasets for kinase research [version 2; referees: 2 approved]

Sharma, R., Schuerer, S. C. & Muskal, S. M., 2016, In : F1000Research. 5, 1366.

Research output: Contribution to journalArticle

3 Scopus citations

The Cell Line Ontology integration and analysis of the knowledge of LINCS cell lines

Ong, E., Xie, J., Ni, Z., Liu, Q., Lin, Y., Stathias, V., Chung, C., Schuerer, S. C. & He, Y., 2016, In : CEUR Workshop Proceedings. 1747

Research output: Contribution to journalArticle

2015

BioAssay Research Database (BARD): Chemical biology and probe-development enabled by structured metadata and result types

Howe, E. A., De Souza, A., Lahr, D. L., Chatwin, S., Montgomery, P., Alexander, B. R., Nguyen, D. T., Cruz, Y., Stonich, D. A., Walzer, G., Rose, J. T., Picard, S. C., Liu, Z., Rose, J. N., Xiang, X., Asiedu, J., Durkin, D., Levine, J., Yang, J. J., Schuerer, S. C. & 10 others, Braisted, J. C., Southall, N., Southern, M. R., Chung, T. D. Y., Brudz, S., Tanega, C., Schreiber, S. L., Bittker, J. A., Guha, R. & Clemons, P. A., Jan 28 2015, In : Nucleic Acids Research. 43, D1, p. D1163-D1170

Research output: Contribution to journalArticle

14 Scopus citations

Editor's Choice: Epigenetic Pathways and Glioblastoma Treatment: Insights from Signaling Cascades

Allen, B. K., Stathias, V., Maloof, M. E., Vidovic, D., Winterbottom, E. F., Capobianco, A. J., Clarke, J., Schuerer, S. C., Robbins, D. J. & Ayad, N., Mar 1 2015, In : Journal of Cellular Biochemistry. 116, 3, p. iii

Research output: Contribution to journalArticle

Epigenetic Pathways and Glioblastoma Treatment: Insights from Signaling Cascades

Allen, B. K., Stathias, V., Maloof, M. E., Vidovic, D., Winterbottom, E. F., Capobianco, A. J., Clarke, J., Schuerer, S. C., Robbins, D. J. & Ayad, N., Mar 1 2015, In : Journal of Cellular Biochemistry. 116, 3, p. 351-363 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

GSK3 inhibitors stabilize Wee1 and reduce cerebellar granule cell progenitor proliferation

Penas, C., Mishra, J. K., Wood, S. D., Schuerer, S. C., Roush, W. R. & Ayad, N., Feb 1 2015, In : Cell Cycle. 14, 3, p. 417-424 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Large-Scale Computational Screening Identifies First in Class Multitarget Inhibitor of EGFR Kinase and BRD4

Allen, B. K., Mehta, S., Ember, S. W. J., Schonbrunn, E., Ayad, N. & Schuerer, S. C., Nov 24 2015, In : Scientific Reports. 5, 16924.

Research output: Contribution to journalArticle

29 Scopus citations

Noribogaine is a G-protein biased κ-opioid receptor agonist

Maillet, E. L., Milon, N., Heghinian, M. D., Fishback, J., Schuerer, S. C., Garamszegi, N. & Mash, D. C., Dec 1 2015, In : Neuropharmacology. 99, p. 675-688 14 p.

Research output: Contribution to journalArticle

22 Scopus citations

Screening of cell cycle fusion proteins to identify kinase signaling networks

Trojanowsky, M., Vidovic, D., Simanski, S., Penas, C., Schuerer, S. C. & Ayad, N., Apr 15 2015, In : Cell Cycle. 14, 8, p. 1274-1281 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Selective Targeting of Extracellular Insulin-Degrading Enzyme by Quasi-Irreversible Thiol-Modifying Inhibitors

Abdul-Hay, S. O., Bannister, T. D., Wang, H., Cameron, M. D., Caulfield, T. R., Masson, A., Bertrand, J., Howard, E. A., McGuire, M. P., Crisafulli, U., Rosenberry, T. R., Topper, C. L., Thompson, C. R., Schuerer, S. C., Madoux, F., Hodder, P. & Leissring, M. A., Dec 18 2015, In : ACS Chemical Biology. 10, 12, p. 2716-2724 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Using the BioAssay Ontology for analyzing high-throughput screening data

Zander Balderud, L., Murray, D., Larsson, N., Vempati, U., Schuerer, S. C., Bjäreland, M. & Engkvist, O., Mar 25 2015, In : Journal of Biomolecular Screening. 20, 3, p. 402-415 14 p.

Research output: Contribution to journalArticle

12 Scopus citations
2014

Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress

Ghosh, R., Wang, L., Wang, E. S., Perera, B. G. K., Igbaria, A., Morita, S., Prado, K., Thamsen, M., Caswell, D., Macias, H., Weiberth, K. F., Gliedt, M. J., Alavi, M. V., Hari, S. B., Mitra, A. K., Bhhatarai, B., Schürer, S. C., Snapp, E. L., Gould, D. B., German, M. S. & 4 others, Backes, B. J., Maly, D. J., Oakes, S. A. & Papa, F. R., Jul 31 2014, In : Cell. 158, 3, p. 534-548 15 p.

Research output: Contribution to journalArticle

189 Scopus citations

An overview of the challenges in designing, integrating, and delivering BARD: A public chemical-biology resource and query portal for multiple organizations, locations, and disciplines

De Souza, A., Bittker, J. A., Lahr, D. L., Brudz, S., Chatwin, S., Oprea, T. I., Waller, A., Yang, J. J., Southall, N., Guha, R., Schürer, S. C., Vempati, U. D., Southern, M. R., Dawson, E. S., Clemons, P. A. & Chung, T. D. Y., Jun 2014, In : Journal of Biomolecular Screening. 19, 5, p. 614-627 14 p.

Research output: Contribution to journalReview article

19 Scopus citations

Casein kinase 1-dependent wee1 protein degradation

Penas, L., Ramachandran, V., Simanski, S., Lee, C., Madoux, F., Rahaim, R. J., Chauhan, R., Barnaby, O., Schurer, S., Hodder, P., Steen, J., Roush, W. R. & Ayad, N. G., Jul 4 2014, In : Journal of Biological Chemistry. 289, 27, p. 18893-18903 11 p.

Research output: Contribution to journalArticle

15 Scopus citations