Shaun P Brothers

Associate Professor

  • 1827 Citations
19972021
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Projects 2016 2021

Post-Traumatic Stress Disorders
Fear
mu Opioid Receptor
Opioid Receptors
Amygdala

Upregulation of Iduronidase Enzyme in MPSI Disease

Brothers, S. P.

National Institutes of Health

4/1/163/31/21

Project: Research projectResearch Project

Iduronidase
Enzyme Replacement Therapy
Up-Regulation
Glycosaminoglycans
Mucopolysaccharidosis I

Research Output 1997 2018

  • 1827 Citations
  • 43 Article
  • 1 Review article

Ex vivo drug sensitivity testing as a means for drug repurposing in esophageal adenocarcinoma

Lohse, I., Al-Ali, H., Volmar, C. H., Alvarez Trotta, A. D., Brothers, S. P., Capobianco, A. J. & Wahlestedt, C. R., Sep 1 2018, In : PloS one. 13, 9, e0203173.

Research output: Contribution to journalArticle

Drug Repositioning
esophageal neoplasms
adenocarcinoma
Adenocarcinoma
Cells
4 Citations

Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study

Swords, R. T., Azzam, D., Al-Ali, H., Lohse, I., Volmar, C. H., Watts, J., Perez, A., Rodriguez, A., Vargas, F., Elias, R., Vega, F., Zelent, A. Z., Brothers, S. P., Abbasi, T., Trent, J., Rangwala, S., Deutsch, Y., Conneally, E., Drusbosky, L., Cogle, C. R. & 1 othersWahlestedt, C. R., Jan 1 2018, In : Leukemia Research. 64, p. 34-41 8 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Pharmaceutical Preparations
Precision Medicine
Therapeutics
Physicians

EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia

Johnstone, A. L., O'Reilly, J. J., Patel, A. J., Guo, Z., Andrade, N. S., Magistri, M., Nathanson, L., Esanov, R., Miller, B. H., Turecki, G., Brothers, S. P., Zeier, Z. R. & Wahlestedt, C. R., Nov 1 2018, In : Neurobiology of Disease. 119, p. 149-158 10 p.

Research output: Contribution to journalArticle

MicroRNAs
Epigenomics
Antipsychotic Agents
Schizophrenia
Prefrontal Cortex
2 Citations

Inhibition of HDAC3 reverses Alzheimer’s disease-related pathologies in vitro and in the 3xTg-AD mouse model

Janczura, K. J., Volmar, C. H., Sartor, G., Rao, S. J., Ricciardi, N. R., Lambert, G., Brothers, S. P. & Wahlestedt, C. R., Nov 20 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 47, p. E11148-E11157

Research output: Contribution to journalArticle

Alzheimer Disease
Pathology
Acetylation
Amyloid beta-Protein Precursor
Phosphorylation

Naturally occurring compounds as pancreatic cancer therapeutics

Lohse, I., Wildermuth, E. & Brothers, S. P., Oct 1 2018, In : Oncotarget. 9, 83, p. 35448-35457 10 p.

Research output: Contribution to journalReview article

Pancreatic Neoplasms
Curcumin
Cannabinoids
Neoplasms
Drug Therapy