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Shaun P Brothers

Associate Professor

  • 2057 Citations
19972021
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  • 6 Similar Profiles
LHRH Receptors Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Cell Membrane Medicine & Life Sciences
Proteins Medicine & Life Sciences
G-Protein-Coupled Receptors Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Cell membranes Chemical Compounds
Neuropeptide Y Receptors Medicine & Life Sciences

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Projects 2016 2021

Development of Nociceptin Receptor Agonists for Post-Traumatic Stress Disorder

Brothers, S. P.

National Institutes of Health

7/21/16 → 4/30/20

Project: Research project

Post-Traumatic Stress Disorders
Fear
mu Opioid Receptor
Opioid Receptors
Amygdala

Upregulation of Iduronidase Enzyme in MPSI Disease

Brothers, S. P.

National Institutes of Health

4/1/16 → 3/31/21

Project: Research project

Iduronidase
Enzyme Replacement Therapy
Up-Regulation
Glycosaminoglycans
Mucopolysaccharidosis I

Research Output 1997 2019

  • 2057 Citations
  • 47 Article
  • 3 Review article

HDAC Inhibitors Induce BDNF Expression and Promote Neurite Outgrowth in Human Neural Progenitor Cells-Derived Neurons

Bagheri, A., Habibzadeh, P., Razavipour, S. F., Volmar, C. H., Chee, N. T., Brothers, S. P., Wahlestedt, C. R., Mowla, S. J. & Faghihi, M. A., Mar 5 2019, In : International journal of molecular sciences. 20, 5

Research output: Contribution to journal › Article

Open Access
Histone Deacetylase Inhibitors
Brain-Derived Neurotrophic Factor
neurons
inhibitors
Neurons
1 Citation (Scopus)

MRNA-to-protein translation in hypoxia

Chee, N. T., Lohse, I. & Brothers, S. P., Mar 30 2019, In : Molecular Cancer. 18, 1, 49.

Research output: Contribution to journal › Review article

Open Access
Protein Biosynthesis
Proteins
Adenosine Triphosphate
Hypoxia
Cell Hypoxia

Ovarian cancer treatment stratification using ex vivo drug sensitivity testing

Lohse, I., Azzam, D. J., Al-Ali, H., Volmar, C. H., Brothers, S. P., Ince, T. A. & Wahlestedt, C., Jan 1 2019, In : Anticancer research. 39, 8, p. 4023-4030 8 p.

Research output: Contribution to journal › Article

Open Access
Ovarian Neoplasms
Pharmaceutical Preparations
Platinum
Therapeutics
Drug Therapy
2 Citations (Scopus)

Vitamin C supplementation expands the therapeutic window of BETi for triple negative breast cancer

Mustafi, S., Camarena, V., Qureshi, R., Yoon, H., Volmar, C. H., Huff, T. C., Sant, D. W., Zheng, L., Brothers, S. P., Wahlestedt, C., Slingerland, J. & Wang, G., Jan 1 2019, In : EBioMedicine.

Research output: Contribution to journal › Article

Open Access
Triple Negative Breast Neoplasms
Ascorbic Acid
Therapeutics
Screening
Histone Deacetylase 1
2 Citations (Scopus)

BET Bromodomain Inhibitors Which Permit Treg Function Enable a Combinatorial Strategy to Suppress GVHD in Pre-clinical Allogeneic HSCT

Copsel, S. N., Lightbourn, C. O., Barreras, H., Lohse, I., Wolf, D., Bader, C. S., Manov, J., Kale, B. J., Shah, D., Brothers, S. P., Perez, V. L., Komanduri, K. V., Wahlestedt, C. R. & Levy, R. B., Jan 1 2018, In : Frontiers in immunology. 9, 1 p.

Research output: Contribution to journal › Article

Open Access
Graft vs Host Disease
Hematopoietic Stem Cell Transplantation
Interleukin-2
Regulatory T-Lymphocytes
Phenotype