Projects per year
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- 6 Similar Profiles
LHRH Receptors
Medicine & Life Sciences
Epigenomics
Medicine & Life Sciences
Cell Membrane
Medicine & Life Sciences
G-Protein-Coupled Receptors
Medicine & Life Sciences
Proteins
Medicine & Life Sciences
Cell membranes
Chemical Compounds
Neuropeptide Y Receptors
Medicine & Life Sciences
Gonadotropin-Releasing Hormone
Medicine & Life Sciences
Network
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Projects 2016 2021
- 2 Active
Development of Nociceptin Receptor Agonists for Post-Traumatic Stress Disorder
7/21/16 → 4/30/20
Project: Research project › Research Project
Post-Traumatic Stress Disorders
Fear
mu Opioid Receptor
Opioid Receptors
Amygdala
Upregulation of Iduronidase Enzyme in MPSI Disease
4/1/16 → 3/31/21
Project: Research project › Research Project
Iduronidase
Enzyme Replacement Therapy
Up-Regulation
Glycosaminoglycans
Mucopolysaccharidosis I
Research Output 1997 2018
Ex vivo drug sensitivity testing as a means for drug repurposing in esophageal adenocarcinoma
Lohse, I., Al-Ali, H., Volmar, C. H., Alvarez Trotta, A. D., Brothers, S. P., Capobianco, A. J. & Wahlestedt, C. R., Sep 1 2018, In : PloS one. 13, 9, e0203173.Research output: Contribution to journal › Article
Drug Repositioning
esophageal neoplasms
adenocarcinoma
Adenocarcinoma
Cells
4
Citations
Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study
Swords, R. T., Azzam, D., Al-Ali, H., Lohse, I., Volmar, C. H., Watts, J., Perez, A., Rodriguez, A., Vargas, F., Elias, R., Vega, F., Zelent, A. Z., Brothers, S. P., Abbasi, T., Trent, J., Rangwala, S., Deutsch, Y., Conneally, E., Drusbosky, L., Cogle, C. R. & 1 others, Jan 1 2018, In : Leukemia Research. 64, p. 34-41 8 p.Research output: Contribution to journal › Article
Acute Myeloid Leukemia
Pharmaceutical Preparations
Precision Medicine
Therapeutics
Physicians
EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia
Johnstone, A. L., O'Reilly, J. J., Patel, A. J., Guo, Z., Andrade, N. S., Magistri, M., Nathanson, L., Esanov, R., Miller, B. H., Turecki, G., Brothers, S. P., Zeier, Z. R. & Wahlestedt, C. R., Nov 1 2018, In : Neurobiology of Disease. 119, p. 149-158 10 p.Research output: Contribution to journal › Article
MicroRNAs
Epigenomics
Antipsychotic Agents
Schizophrenia
Prefrontal Cortex
2
Citations
Inhibition of HDAC3 reverses Alzheimer’s disease-related pathologies in vitro and in the 3xTg-AD mouse model
Janczura, K. J., Volmar, C. H., Sartor, G., Rao, S. J., Ricciardi, N. R., Lambert, G., Brothers, S. P. & Wahlestedt, C. R., Nov 20 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 47, p. E11148-E11157Research output: Contribution to journal › Article
Alzheimer Disease
Pathology
Acetylation
Amyloid beta-Protein Precursor
Phosphorylation
Naturally occurring compounds as pancreatic cancer therapeutics
Lohse, I., Wildermuth, E. & Brothers, S. P., Oct 1 2018, In : Oncotarget. 9, 83, p. 35448-35457 10 p.Research output: Contribution to journal › Review article
Pancreatic Neoplasms
Curcumin
Cannabinoids
Neoplasms
Drug Therapy