Scott Welford

Associate Professor

  • 4087 Citations
1987 …2020

Research output per year

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Research Output

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Article
2019

Early Cellular Responses of Prostate Carcinoma Cells to Sepantronium Bromide (YM155) Involve Suppression of mTORC1 by AMPK

Danielpour, D., Gao, Z., Zmina, P. M., Shankar, E., Shultes, B. C., Jobava, R., Welford, S. & Hatzoglou, M., Dec 1 2019, In : Scientific reports. 9, 1, 11541.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Mlh1 deficiency increases the risk of hematopoietic malignancy after simulated space radiation exposure

Patel, R., Zhang, L., Desai, A., Hoenerhoff, M. J., Kennedy, L. H., Radivoyevitch, T., Ban, Y., Chen, X. S., Gerson, S. L. & Welford, S. M., May 1 2019, In : Leukemia. 33, 5, p. 1135-1147 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Spermidine/spermine N1-acetyltransferase 1 is a gene-specific transcriptional regulator that drives brain tumor aggressiveness

Thakur, V. S., Aguila, B., Brett-Morris, A., Creighton, C. J. & Welford, S., Jan 1 2019, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

1 Scopus citations

The Ig superfamily protein PTGFRN coordinates survival signaling in glioblastoma multiforme

Aguila, B., Morris, A. B., Spina, R., Bar, E., Schraner, J., Vinkler, R., Sohn, J. W. & Welford, S. M., Oct 10 2019, In : Cancer letters. 462, p. 33-42 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

The membrane tethered matrix metalloproteinase MT1-MMP triggers an outside-in DNA damage response that impacts chemo- and radiotherapy responses of breast cancer

Thakur, V., Zhang, K., Savadelis, A., Zmina, P., Aguila, B., Welford, S. M., Abdul-Karim, F., Bonk, K. W., Keri, R. A. & Bedogni, B., Feb 28 2019, In : Cancer letters. 443, p. 115-124 10 p.

Research output: Contribution to journalArticle

3 Scopus citations
2018

MMR Deficiency Does Not Sensitize or Compromise the Function of Hematopoietic Stem Cells to Low and High LET Radiation

Patel, R., Qing, Y., Kennedy, L., Yan, Y., Pink, J., Aguila, B., Desai, A., Gerson, S. L. & Welford, S. M., Jan 1 2018, (Accepted/In press) In : Stem Cells Translational Medicine.

Research output: Contribution to journalArticle

2 Scopus citations
2017

Development and Validation of a Small Animal Immobilizer and Positioning System for the Study of Delivery of Intracranial and Extracranial Radiotherapy Using the Gamma Knife System

Awan, M. J., Dorth, J., Mani, A., Kim, H., Zheng, Y., Mislmani, M., Welford, S., Yuan, J., Wessels, B. W., Lo, S. S., Letterio, J., Machtay, M., Sloan, A. & Sohn, J. W., Apr 1 2017, In : Technology in Cancer Research and Treatment. 16, 2, p. 203-210 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism

Du, W., Zhang, L., Brett-Morris, A., Aguila, B., Kerner, J., Hoppel, C. L., Puchowicz, M., Serra, D., Herrero, L., Rini, B. I., Campbell, S. & Welford, S. M., Dec 1 2017, In : Nature communications. 8, 1, 1769.

Research output: Contribution to journalArticle

54 Scopus citations

Long-Term Deficits in Behavior Performances Caused by Low- and High-Linear Energy Transfer Radiation

Patel, R., Arakawa, H., Radivoyevitch, T., Gerson, S. L. & Welford, S. M., Dec 2017, In : Radiation research. 188, 6, p. 672-680 9 p.

Research output: Contribution to journalArticle

4 Scopus citations
2016

Effect of protein tyrosine phosphatase non-receptor type 12 (PTPN12) downregulation on the radiosensitivity of non-small cell lung cancer

Hu, W., Liu, Z., Zhang, W., Welford, S. & Su, J., Jan 1 2016, In : Chinese Journal of Clinical Oncology. 43, 7, p. 285-290 6 p.

Research output: Contribution to journalArticle

Macrophage migration inhibitory factor secretion is induced by ionizing radiation and oxidative stress in cancer cells

Gupta, Y., Pasupuleti, V., Du, W. & Welford, S. M., Jan 7 2016, In : PloS one. 11, 1, e0146482.

Research output: Contribution to journalArticle

11 Scopus citations
2015

Phase i dose-escalation study of stereotactic body radiotherapy (SBRT) for poor surgical candidates with localized renal cell carcinoma

Ponsky, L., Lo, S. S., Zhang, Y., Schluchter, M., Liu, Y., Patel, R., Abouassaly, R., Welford, S., Gulani, V., Haaga, J. R., Machtay, M. & Ellis, R. J., Oct 1 2015, In : Radiotherapy and Oncology. 117, 1, p. 183-187 5 p.

Research output: Contribution to journalArticle

36 Scopus citations

SAT1 and glioblastoma multiforme: Disarming the resistance

Brett-Morris, A., Mislmani, M. & Welford, S., Jul 3 2015, In : Molecular and Cellular Oncology. 2, 3, e983393.

Research output: Contribution to journalArticle

1 Scopus citations
2014

Dysregulated D-dopachrome Tautomerase, a Hypoxiainducible Factor-dependent Gene, cooperates with Macrophage migration inhibitory factor in Renal Tumorigenesis

Pasupuleti, V., Du, W., Gupta, Y., Yeh, I. J., Montano, M., Magi-Galuzzi, C. & Welford, S. M., Feb 7 2014, In : Journal of Biological Chemistry. 289, 6, p. 3713-3723 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Establishing a process of irradiating small animal brain using a CyberKnife and a microCT scanner

Kim, H., Fabien, J., Zheng, Y., Yuan, J., Brindle, J., Sloan, A., Yao, M., Lo, S., Wessels, B., Machtay, M., Welford, S. & Sohn, J. W., Feb 2014, In : Medical physics. 41, 2, 021715.

Research output: Contribution to journalArticle

7 Scopus citations

Expression of glutamine transporter Slc38a3 (SNAT3) during acidosis is mediated by a different mechanism than tissue-specific expression

Balkrishna, S., Bröer, A., Welford, S. M., Hatzoglou, M. & Bröer, S., May 2014, In : Cellular Physiology and Biochemistry. 33, 5, p. 1591-1606 16 p.

Research output: Contribution to journalArticle

8 Scopus citations

Ionizing radiation causes increased tau phosphorylation in primary neurons

Li, L., Wang, W., Welford, S., Zhang, T., Wang, X. & Zhu, X., Jan 1 2014, In : Journal of Neurochemistry. 131, 1, p. 86-93 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

The polyamine catabolic enzyme sat1 modulates tumorigenesis and radiation response in gbm

Brett-Morris, A., Wright, B. M., Seo, Y., Pasupuleti, V., Zhang, J., Lu, J., Spina, R., Bar, E. E., Gujrati, M., Schur, R., Lu, Z. R. & Welford, S. M., Dec 1 2014, In : Cancer Research. 74, 23, p. 6925-6934 10 p.

Research output: Contribution to journalArticle

20 Scopus citations
2013

HEXIM1 down-regulates hypoxia-inducible factor-1α protein stability

Yeh, I. J., Ogba, N., Bensigner, H., Welford, S. M. & Montano, M. M., Dec 1 2013, In : Biochemical Journal. 456, 2, p. 195-204 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Tumor-derived macrophage migration inhibitory factor promotes an autocrine loop that enhances renal cell carcinoma

Du, W., Wright, B. M., Li, X., Finke, J., Rini, B. I., Zhou, M., He, H., Lal, P. & Welford, S. M., Mar 14 2013, In : Oncogene. 32, 11, p. 1469-1474 6 p.

Research output: Contribution to journalArticle

22 Scopus citations
2010

Renal oxygenation suppresses VHL loss-induced senescence that is caused by increased sensitivity to oxidative stress

Welford, S. M., Dorie, M. J., Li, X., Haase, V. H. & Giaccia, A. J., Oct 1 2010, In : Molecular and cellular biology. 30, 19, p. 4595-4603 9 p.

Research output: Contribution to journalArticle

31 Scopus citations
2009

Hypoxia-Inducible mir-210 Regulates Normoxic Gene Expression Involved in Tumor Initiation

Huang, X., Ding, L., Bennewith, K. L., Tong, R. T., Welford, S. M., Ang, K. K., Story, M., Le, Q. T. & Giaccia, A. J., Sep 24 2009, In : Molecular Cell. 35, 6, p. 856-867 12 p.

Research output: Contribution to journalArticle

420 Scopus citations
2006

DNA damage during reoxygenation elicits a Chk2-dependent checkpoint response

Freiberg, R. A., Hammond, E. M., Dorie, M. J., Welford, S. M. & Giaccia, A. J., Mar 1 2006, In : Molecular and cellular biology. 26, 5, p. 1598-1609 12 p.

Research output: Contribution to journalArticle

46 Scopus citations

HIF1α delays premature senescence through the activation of MIF

Welford, S. M., Bedogni, B., Gradin, K., Poellinger, L., Powell, M. B. & Giaccia, A. J., Dec 15 2006, In : Genes and Development. 20, 24, p. 3366-3371 6 p.

Research output: Contribution to journalArticle

115 Scopus citations
51 Scopus citations
2005

The hypoxic microenvironment of the skin contributes to Akt-mediated melanocyte transformation

Bedogni, B., Welford, S. M., Cassarino, D. S., Nickoloff, B. J., Giaccia, A. J. & Powell, M. B., Dec 1 2005, In : Cancer Cell. 8, 6, p. 443-454 12 p.

Research output: Contribution to journalArticle

125 Scopus citations
2004
74 Scopus citations
2003

PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteins

Deneen, B., Welford, S. M., Ho, T., Hernandez, F., Kurland, I. & Denny, C. T., Jun 1 2003, In : Molecular and cellular biology. 23, 11, p. 3897-3908 12 p.

Research output: Contribution to journalArticle

65 Scopus citations
2001

DNA Binding Domain-independent Pathways Are Involved in EWS/FLI1-mediated Oncogenesis

Welford, S. M., Hebert, S. P., Deneen, B., Arvand, A. & Denny, C. T., Nov 9 2001, In : Journal of Biological Chemistry. 276, 45, p. 41977-41984 8 p.

Research output: Contribution to journalArticle

53 Scopus citations

The cooh-terminal domain of FLI-1 is necessary for full tumorigenesis and transcriptional modulation by EWS/FLI-11,2

Arvand, A., Teitell, M. A., Welford, S. M., Teitell, M. A., Denny, C. T., Teitell, M. A., Denny, C. T. & Denny, C. T., Jul 1 2001, In : Cancer Research. 61, 13, p. 5311-5317 7 p.

Research output: Contribution to journalArticle

42 Scopus citations
2000

EWS-FLI1, EWS-ERG, and EWS-ETV1 oncoproteins of Ewing tumor family all suppress transcription of transforming growth factor β type II receptor gene

Im, Y. H., Kim, H. T., Lee, C., Poulin, D., Welford, S., Sorensen, P. H. B., Denny, C. T. & Kim, S. J., Mar 15 2000, In : Cancer Research. 60, 6, p. 1536-1540 5 p.

Research output: Contribution to journalArticle

88 Scopus citations
1998

Detection of differentially expressed genes in primary tumor tissues using representational differences analysis coupled to microarray hybridization

Welford, S. M., Gregg, J., Chen, E., Garrison, D., Sorensen, P. H., Denny, C. T. & Nelson, S. F., Jun 15 1998, In : Nucleic acids research. 26, 12, p. 3059-3065 7 p.

Research output: Contribution to journalArticle

151 Scopus citations

EWS/FLI1 up regulates mE2-C, a cyclin-selective ubiquitin conjugating enzyme involved in cyclin B destruction

Arvand, A., Bastians, H., Welford, S. M., Thompson, A. D., Ruderman, J. V. & Denny, C. T., Oct 22 1998, In : Oncogene. 17, 16, p. 2039-2045 7 p.

Research output: Contribution to journalArticle

77 Scopus citations